Assessment of intervertebral disc degeneration with magnetic resonance single-voxel spectroscopy

Magnetic Resonance in Medicine

Volumn 62, Issue 5, 2009, Pages 1140-1146

  Zuo, Jin ^a   Saadat, Ehsan ^a   Romero, Adan ^b   Loo, Kimberly ^c   Li, Xiaojuan ^a   Link, Thomas M ^a   Kurhanewicz, John ^a   Majumdar, Sharmila ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b CALIFORNIA STATE UNIVERSITY   (United States)

^c Piedmont Hills High School   (United States)

Author keywords

Glycosaminoglycan; Intervertebral disc degeneration; Metabolite quantitation; Pfirrmann grade; Single voxel MR spectroscopy

Indexed keywords

GRADING; IMPLANTS (SURGICAL); MAGNETIC RESONANCE SPECTROSCOPY; MAMMALS; METABOLITES; PAPAIN; PRESSES (MACHINE TOOLS); SCANNING;

CARBOHYDRATE REGIONS; GLYCOSAMINOGLYCANS; INTER-VERTEBRAL DISC DEGENERATION; INTERVERTEBRAL DISCS; MAGNETIC RESONANCE SCANNERS; MR SPECTROSCOPY; POINT RESOLVED SPECTROSCOPIES; SINGLE-VOXEL SPECTROSCOPIES;

MAGNETIC RESONANCE;

CARBOHYDRATE; CHOLINE; GLYCOSAMINOGLYCAN; LACTIC ACID; LIPID; PAPAIN;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DISEASE SEVERITY; HUMAN; HUMAN TISSUE; INTERVERTEBRAL DISK DEGENERATION; NON INVASIVE MEASUREMENT; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; QUANTITATIVE DIAGNOSIS; REPRODUCIBILITY; TISSUE METABOLISM;

EID: 70449371837     PISSN: 07403194     EISSN: 15222594     Source Type: Journal    
DOI: 10.1002/mrm.22093     Document Type: Article

References (36)

1. 1rho-weighted magnetic resonance imaging. Spine 2006;31:1253-1257.
2. Paajanen H, Erkintalo M, Parkkola R. Age-dependent correlation of low-back pain and lumbar disc degeneration. Arch Orthop Trauma Surg 1997;116:106-107. (Pubitemid 26421673)
3. Urban JP, McMullin JF. Swelling pressure of the lumbar intervertebral discs: influence of age, spinal level, composition, and degeneration. Spine 1988;13:179-187.
4. Antoniou J, Steffen T, Nelson F, Winterbottom N, Hollander AP, Poole RA, Aebi M, Alini M. The human lumbar intervertebral disc: evidence for changes in the biosynthesis and denaturation of the extracellular matrix with growth, maturation, ageing and degeneration. J Clin Invest 1996;98:996-1003. (Pubitemid 26293318)
5. Kirkaldy-Willis WH, Wedge JH, Young-Hing K, Reilly J. Pathology and pathogenesis of lumbar spondylosis and stenosis. Spine 1978;3:319-328.
6. Andersson GB. What are the age-related changes in the spine? Baillieres Clin Rheumatol 1998;12:161-173.
7. Kistler MW, Pribram HW. Epidural venography in the diagnosis of lumbar disc disease. Surg Neurol 1976;5:287-291.
8. Griebel R, Tchang S, Khan M, Varughese G. Correlation of computed tomography with surgical diagnosis in lumbar disc disease. Can J Neurol Sci 1983;10:248-251. (Pubitemid 14243109)
9. Finch P. Technology insight: imaging of low back pain. Nat Clin Pract Rheumatol 2006;2:554-561. (Pubitemid 44489959)
10. Collis JS Jr, Gardner WJ. Lumbar discography. Analysis of 600 degenerated disks and diagnosis of degenerated disk disease. JAMA 1961;178:67-70.
11. Modic MT, Ross JS. Magnetic resonance imaging in the evaluation of low back pain. Orthop Clin North Am 1991;22:283-301.
12. 2 study. Magn Reson Imaging 1989;7:17-23.
13. Pfirrmann CW, Metzdorf A, Zanetti M, Hodler J, Boos N. Magnetic resonance classification of lumbar intervertebral disc degeneration. Spine 2001:26:1873-1878. (Pubitemid 32844681)
14. 2) in the normal intervertebral disc and its relationship to water content. Spine 1993;18:2271-2275.
15. Chiu EJ, Newitt DC, Segal MR, Hu SS, Lotz JC, Majumdar S. Magnetic resonance imaging measurement of relaxation and water diffusion in the human lumbar intervertebral disc under compression in vitro. Spine 2001;26:437-444.
16. Weidenbaum M, Foster RJ, Best BA, Saed-Najad F, Nickoloff E, Newhouse J, Ratcliffe A, Mow VC. Correlating magnetic resonance imaging with the biochemical content of the normal human intervertebral disc. J Orthop Res 1992;10:552-561.
17. 1(rho)-weighted magnetic resonance imaging. Eur Spine J 2006;15(Suppl 3);S338-S344.
18. 1rho imaging of the intervertebral disc. Magn Reson Imaging 2006;24:1001-1007.
19. Antoniou J, Demers CN, Beaudoin G, Goswami T, Mwale F, Aebi M, Alini M. Apparent diffusion coefficient of intervertebral discs related to matrix composition and integrity. Magn Reson Imaging 2004;22:963-972. (Pubitemid 38993526)
20. 2 relaxation time measurements to evaluate disc degeneration. A quantitative MR study of young patients with previous vertebral fracture. Acta Radiol 2001;42:585-591.
21. Keshari KR, Zektzer AS, Swanson MG, Majumdar S, Lotz JC, Kurhanewicz J. Characterization of intervertebral disc degeneration by high-resolution magic angle spinning (HR-MAS) spectroscopy. Magn Reson Med 2005;53:519-527. (Pubitemid 40332271)
22. Keshari KR, Lotz JC, Kurhanewicz J, Majumdar S. Correlation of HR-MAS spectroscopy derived metabolite concentrations with collagen and proteoglycan levels and Thomson grade in the degenerative disc. Spine 2005;30:2683-2688. (Pubitemid 41780378)
23. Keshari KR, Lotz JC, Link TM, Hu S, Majumdar S, Kurhanewicz J. Lactic acid and proteoglycans as metabolic markers for discogenic back pain. Spine 2008;33:312-317. (Pubitemid 351322939)
24. Prichard JW. What the clinician can learn from MRS lactate measurements. NMR Biomed 1991;4:99-102.
25. Bradford DS, Oegema TR Jr, Cooper KM, Wakano K, Chao EY. Chymopapain, chemonucleolysis, and nucleus pulposus regeneration. A biochemical and biomechanical study. Spine 1984;9:135-147.
26. Roberts S, Menage J, Sivan S, Urban JPG. Bovine explant model of degeneration of the intervertebral disc. BMR Musculoskelet Disord 2008;9:24.
27. Hoemann CD. Molecular and biochemical assays of cartilage component. Methods Mol Med 2004;101:127-156.
28. Le Roux P, Gilles RJ, McKinnon GC, Carlier PG. Optimized outer volume suppression for single-shot fast spin-echo cardiac imaging. J Magn Reson Imaging 1998;8:1022-1032. (Pubitemid 28481786)
29. Bland JM, Altman DG. Statistical methods for assessing agreement between two methods of clinical measurement. Lancet 1986;1:307-310. (Pubitemid 16134762)
30. Nelson SJ. Analysis of volume MRI and MR spectroscopic imaging data for the evaluation of patients with brain tumors. Magn Reson Med 2001;46:228-239.
31. Li X, Nelson SJ. Reliable in vivo lactate and lipid estimation in glioma patients. In: Proceedings of the 25th Annual International Conference of the IEEE Engineering in Medicine and Biology Society; Cancun, Mexico, 2003;482-485.
32. 1H-MR spectroscopy of hippocampal structures in healthy adults at 1.5 Tesla - how reproducible are the results? NMR Biomed 2005;18:195-201.
33. Buirski G, Silberstein M. They symptomatic lumbar disc in patients with low-back pain. Magnetic resonance imaging appearances in both a symptomatic and control population. Spine 1993;18:1808-1811.
34. Frahm J, Bruhn H, Gyngell ML, Merboldt KD, Hanlcke W, Sauter R. Localized proton NMR spectroscopy in different regions of the human brain in vivo. Relaxation times and concentrations of cerebral metabolites. Magn Reson Med 1989;9:79-93.
35. Williams SR, Gadian DG, Proctor E. A method for lactate detection in vivo by spectral editing without the need for double irradiation. J Magn Reson 1986; 66: 562-567.
36. Sotak CH, Freeman DM, Hurd RE. The unequivocal determination of in vivo lactic acid using two dimensional double-quantum coherence-transfer spectroscopy. J Magn Reson 1988;78:382-388.