Evaluation of cytogenetic effects of deltamethrin in root meristem cells of Allium sativum and Allium cepa: A possible mechanism of chromosome damage

Toxicological and Environmental Chemistry

Volumn 91, Issue 3, 2009, Pages 577-594

  Saxena, P N ^a   Murthy, R C ^a   Gupta, S K ^a  

^a CSIR INDIAN INSTITUTE OF TOXICOLOGY RESEARCH   (India)

Author keywords

Allium sativum and Allium cepa; Chromosome breaks; Deltamethrin; Deltamethrin DNA interactions; FTIR and UV spectrum; Molecular orbital calculations

Indexed keywords

ALLIUM SATIVUM AND ALLIUM CEPA; DELTAMETHRIN; DELTAMETHRIN-DNA INTERACTIONS; FTIR AND UV SPECTRUM; MOLECULAR ORBITAL CALCULATIONS;

ABERRATIONS; ATOMIC SPECTROSCOPY; DNA; FOURIER TRANSFORM INFRARED SPECTROSCOPY; GENES; LIGHT ABSORPTION; MOLECULAR MODELING; MOLECULAR ORBITALS; NUCLEIC ACIDS; SOIL POLLUTION; SOILS; SPECTROSCOPIC ANALYSIS; TESTING; ULTRAVIOLET SPECTROSCOPY;

SOIL TESTING;

CHROMOSOME; CYTOGENETICS; DELTAMETHRIN; ENVIRONMENTAL MONITORING; FTIR SPECTROSCOPY; GENOTOXICITY; MONOCOTYLEDON; ROOT SYSTEM; SOIL POLLUTION; TOXICITY TEST;

ALLIUM CEPA; ALLIUM SATIVUM;

EID: 70449371834     PISSN: 02772248     EISSN: 10290486     Source Type: Journal    
DOI: 10.1080/02772240802268965     Document Type: Article

References (41)

1. Amer, S.M., and E.I. Aboul-Ela. 1985. Cytogenetic effects of pesticides: Induction of micronuclei in mouse bone marrow by the insecticides cypermethrin and rotenone. Mutation Research 155: 135-42.
2. Amer, S.M., A.A. Ibrahim, and K.M. El-Sherbeny. 1993. Induction of chromosomal aberrations and sister chromatid exchanges in vivo and in vitro by the insecticide cypermethrin. Journal of Applied Toxicology: JAT 13: 341-5.
3. Bellamy, L.J. 1975. The infrared spectra of complex molecules. London: Chapman and Hall.
4. Bhuniya, S.P., and P.C. Pati. 1988. Genotoxic effects of the synthetic pyrethroids insecticides cypermethrin in mice in vivo. Toxicology Letters 41: 223-30.
5. Celik, A., B. Mazmanci, Y. Camlica, A. Askin, and U. Comelekoglu. 2003. Cytogenetic effects of lambda-cyhalothrin on Wistar rat bone marrow. Mutation Research 539: 91-7.
6. Celik, A., B. Mazmanci, Y. Camlica, U. Comelekoglu, and A. Askin. 2005. Evaluation of cytogenetic effects of lambda-cyhalothrin on Wistar rat bone marrow by gavage administration. Ecotoxicology and Environmental Safety 61: 128-33.
7. Chauhan, L.K.S., T.S.S. Dikshith, and V. Sundararaman. 1986. Effect of Deltamethrin on plant cells I. Cytological effects of Deltamethrin on the root meristem cells of Allium cepa. Mutation Research 171: 25-30.
8. Chauhan, L.K.S., P.N. Saxena, and S.K. Gupta. 1999a. Cytogenetic effects of cypermethrin and fenvalerate on the root meristem cells of Allium cepa. Environmental and Experimental Botany 42: 181-9.
9. Chauhan, L.K.S., P.N. Saxena, and S.K. Gupta. 1999b. Effect of deltamethrin on the ultrastructures of the root meristem cells of Allium cepa. Pesticide Biochemistry and Physiology 64: 135-47.
10. Dash, S., K.K. Panda, and B.B. Panda. 1988. Biomonitoring of low levels of mercurial derivatives in water and soil by Allium micronucleus assay. Mutation Research 203: 11-21.
11. El-Khatib, E.N., M.A. Mona Abd El-Aziz, Y. Badr, and N. Kamal. 2006. In vivo genotoxicity of the synthetic pyrethroid pesticide "cypermethrin" in rat liver cells by Comet assay. Toxicology Letters 164, no. Suppl. 1: S289.
12. Fiskesjo, G. 1985. The Allium test as a standard in environmental monitoring. Heriditas 102: 99-102.
13. Giray, B., A. Gurbay, and F. Hincal. 2001. Cypermethrin-induced oxidative stress in rat brain and liver is prevented by vitamin E or allopurinol. Toxicology Letters 118: 139-46.
14. Grant, W.F. 1978. Chromosome aberrations in plants as a monitoring system. Environmental Health Perspectives 27: 37-43.
15. Hassal, K.A. 1982. The chemistry of pesticides, their metabolism, mode of action and uses in crop protection. 67-96. London and Bansignstoke: The Macmillan Press Ltd.
16. Kuriyama, R., and H. Sakai. 1974. Role of tubulin-SH group in polymerization to microtubules. Journal of Biochemistry 76: 651-4.
17. Leahey, J.P. 1985. The pyrethroids insecticides. London: Taylor and Francis.
18. Lewis, D.F.V., C. Loannides, and D.V. Parke. 1989. Prediction of chemical carcinogenicity from their molecular and electronic structure. Toxicology Letters 45: 1-13.
19. Lewis, D.F.V., C. Loannides, and D.V. Parke. 1998. Further evaluation of COMPACT, the molecular orbital approach for the prospective safety evaluation of chemicals. Mutation Research 412: 41-54.
20. Liu, X.M., S. Sonar, C.P. Lee, M. Coleman, U.L. Rajbhandary, and K.J. Rothschild. 1995. Site directed isotope labellling and FTIR spectroscopy: Assignment of tyrosine bands in the bR-M difference spectroscopy of bacteriorhodopsin. Biophysical Chemistry 56: 63-70.
21. Luo, L.Z., K.M. Werner, S.M. Gollin, and W.S. Saunders. 2004. Cigarette smoke induces anaphase bridges and genomic imbalances in normal cells. Mutation Research 554: 375-85.
22. McGill, M., P. Sen, and T.C. Hsu. 1974. Effect of ethidium bromide on mitosis and chromosomes. A possible material basis for chromosome stickiness. Chromosoma 47: 157-67.
23. Onozato, M., and S. Ohshima. 2006. Analysis of mutagenicity of nitrobenzanthrones by molecular orbital calculations. Polycyclic Aromatic Compounds 26: 93-101.
24. Owen, J.D. 1975. Absolute configuration of the most potent isomer of the pyrethroid insecticide -cyano-3-phenoxybenzyl cis-3-(2,2-dibromovinyl)-2,2-dimethyl-cyclopropane-carboxylate by crystal structure analysis. Journal of the Chemical Society. Perkin Transactions 1: 1865-8.
25. Pati, P.C., and S.P. Bhuniya. 1989. Cytogenetic effects of fenvalerate in mammalians in vivo test system. Mutation Research 222: 149-54.
26. Pluijmen, M., C. Devron, R. Montesano, C. Malaveille, A. Hautefeuille, and H. Bartsch. 1984. Lack of mutagenicity of synthetic pyrethroids in Salmonella typhemurium strains and V79 Chinese hamster cells. Mutation Research 137: 7-15.
27. Polokova, H., and M. Vargova. 1983. Evaluation of the mutagenic effects of deltamethrin: cytogenetic analysis of bone marrow. Mutation Research 120: 167-71.
28. Rank, J., and M.H. Nielson. 1997. Allium cepa anaphase-telophase root tip chromosome aberration assay on N-methyl-N-nitrosourea, malic hydrazide, sodium azide, ethyl methyl sulfonate. Mutation Research 390: 121-7.
29. Saha, S., and A. Kaviraj. 2008. Acute toxicity of the synthetic pyrethroids cypermehtrin to some freshwater organisms. Bulletin of Environmental Contamination and Toxicology 80: 49-52.
30. Saxena, P.N., L.K.S. Chauhan, S. Chandra, and S.K. Gupta. 2004. Genotoxic effects of diuron contaminated soil on the root meristem cells of Allium sativum: A Possible mechanism of chromosome damage. Toxicology Mechanisms and Methods 14: 281-6.
31. Saxena, P.N., L.K.S. Chauhan, and S.K. Gupta. 2005. Cytogenetic effects of commercial formulation of cypermethrin in root meristem cells of Allium sativum: Spectroscopic basis of chromosome damage. Toxicology 216: 244-52.
32. Saxena, P.N., and V.D. Gupta. 1994. Normal vibrations and valence charge distribution in relation to bioactivity of gammexene. Indian Journal of Biochemistry and Biophysics 31: 198-202.
33. Saxena, P.N., and V.D. Gupta. 2005. Role of molecular geometry, valence charge distribution and vibrational modes in the bioactivity of cyclodiene insecticides. Journal of Applied Toxicology: JAT 25: 39-46.
34. Seiler, J.P. 1979. Herbicidal phenylalkylureas as possible mutagens. II. Chemical basis of mutagenic activity. Pesticide Biochemistry and Physiology 12: 183-90.
35. Soderlund, D.M., J.M. Clark, L.P. Sheets, L.S. Mullin, V.J. Piccirillo, D. Sargent, J.T. Stevens, and M.L. Weiner. 2002. Mechanism of pyrethroid neurotoxicity: implication for cumulative risk assessment. Toxicology 171: 3-59.
36. Srivastava, R.C., J. Froehlich, and G.L. Eichhorn. 1978. The effect of platinum binding on the structure of DNA and its function in RNA synthesis. Biochimie 60: 879-91.
37. Surrales, J., N. Xamena, A. Creus, J. Catalan, H. Norppa, and R. Marcos. 1995. Induction of micronucleus by five pyrethroids insecticides in whole blood and isolated human lymphocytes cultures. Mutation Research 341: 169-84.
38. Tokiwa, H., N. Sera, K. Fukuhara, H. Utsumi, S. Sasaki, and N. Miyata. 2003. Structure activity relationship between Salmonella-mutagenicity and nitro-orientation of nitroazaphenanthrenes. Chemico-Biological Interactions 146: 19-25.
39. World Health Organisation. 1985. Guide to short term tests for detecting mutagenic and carcinogenic chemicals. Environmental Health Criteria 51, 208 (Geneva).
40. Xu, W., B. Tong, and O. Huang. 2001. Chemical assessment of mutagenicity of halocarbons: FTIR, UV spectrum characteristics of guanine-halohydrocarbon adducts. Huan jing ke xue1/4Huanjing kexue/[bian ji, Zhongguo ke xue yuan huan jing ke xue wei yuan hui "Huan jing ke xue" bian ji wei yuan hui.] 22, 67-70.
41. Zhang, M., H.Y.N. Holman, M. Ferrari, and J.C. Hunter-Cevera. 1999. Synchroton infrared microspectroscopy for assessment of mutagenicity of metal implants. Biomedical materials-drug delivery, implants and tissue engineering. MRS Symposium Series: 163-9.