Antenatal steroids and antioxidant enzyme activity in preterm infants: Influence of gender and timing

Antioxidants and Redox Signaling

Volumn 11, Issue 12, 2009, Pages 2945-2955

  Vento, Máximo ^a   Aguar, Marta ^a   Escobar, Javier ^b   Arduini, Alessandro ^b   Escrig, Raquel ^a   Brugada, María ^a   Izquierdo, Isabel ^a   Asensi, Miguel Angel ^b   Sastre, Juan ^b   Saenz, Pilar ^a   Gimeno, Ana ^a  

^a HOSPITAL UNIVERSITARIO LA FE   (Spain)

^b UNIVERSITY OF VALENCIA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; BETAMETHASONE; GLUTATHIONE;

ADULT; ANTIOXIDANT ACTIVITY; ARTICLE; ARTIFICIAL VENTILATION; BRAIN HEMORRHAGE; CLINICAL TRIAL; COHORT ANALYSIS; CONTROLLED STUDY; CORTICOSTEROID THERAPY; ENZYME ACTIVITY; FEMALE; GESTATIONAL AGE; HUMAN; INFANT; LUNG DYSPLASIA; MALE; NEONATAL RESPIRATORY DISTRESS SYNDROME; NEWBORN; OUTCOME ASSESSMENT; OXIDATIVE STRESS; OXYGEN THERAPY; PREMATURITY; PRENATAL PERIOD; PRIORITY JOURNAL; PROSPECTIVE STUDY; RETROLENTAL FIBROPLASIA; SEX DIFFERENCE; UMBILICAL CORD BLOOD;

ADOLESCENT; ADRENAL CORTEX HORMONES; ADULT; ANTIOXIDANTS; CATALASE; FEMALE; HUMANS; INFANT, NEWBORN; INFANT, PREMATURE; MALE; OXIDATIVE STRESS; PREGNANCY; PROSPECTIVE STUDIES; SEX FACTORS; SUPEROXIDE DISMUTASE; YOUNG ADULT;

EID: 70449127252     PISSN: 15230864     EISSN: None     Source Type: Journal    
DOI: 10.1089/ars.2009.2671     Document Type: Article

References (52)

1. Akerboom TPM and Sies H. Glutathione reductase assay. Methods Enzymol 77: 373-382, 1981.
2. Allen RG and Balin AK. Oxidative influence on development and differentiation: an overview of a free radical theory of development. Free Radic Biol Med 6: 631-661, 1989.
3. Andersson S, Kheiter A, and Merritt TA. Oxidative inacti-vation of surfactants. Lung 177: 179-189, 1999
4. NIH consensus statement online. Antenatal corticosteroids revisited: repeat courses. August 17-18. NIH consensus statement online 17: 1-10, 2000.
5. Arima M, Kumai T, Asoh K, Takeba Y, Murano K, Goto K, Tsuzuki Y, Mizuno M, Kojima T, Kobayashi S, and Koita-bashi Y. Effects of antenatal dexamethasone on antioxidant enzymes and nitric oxide synthase in the rat lung. J Pharmacol Sci 106: 242-248, 2008
6. Asensi M, Sastre J, Pallardó FV, Garćia de la Asunción J, Estrela JM, and Viña JA. High-performance liquid chroma-tography method for measurement of oxidized glutathione in biological samples. Ann Biochem 217: 323-338, 1994.
7. Asensi M, Sastre J, Pallardó FV, Lloret A, Lehner M, Garcia-de-la-Asunción J, and Viña J. Ratio of reduced to oxidized glutathione as indicator of oxidative stress status and DNA damage. Methods Enzymol 299: 267-276, 1999.
8. Asikainen TM and White CW. Pulmonary antioxidant defenses in the preterm newborn with respiratory distress and bronchopulmonary dysplasia in evolution: implications for antioxidant therapy. Antioxid Redox Signal 6: 155-167, 2004.
9. Bunt JE, Carnielli VP, Darcos Wattimena JL, Hop WC, Sauer PJ, and Zimmerman LJ. The effect in premature infants of prenatal corticosteroids on endogenous surfactant synthesis as measured with stable isotopes. Am J Respir Crit Care Med 162: 844-849, 2000.
10. Comporti M, Signorini C, Leoncini S, Buonocore G, Rossi V, and Ciccoli L. Plasma F2-isoprostanes are elevated in new-borns and inversely correlated to gestational age. Free Radic Biol Med 37: 724-732, 2004.
11. Crowley P. Prophylactic corticosteroids for preterm birth. Cochrane Database Systematic Rev 1: CD000065, 1996.
12. Crowther CA, Doyle LW, Haslam RR, Hiller JE, Harding JE, Robinson JS, and for the ACTORDS Study Group. Outcomes at 2 years of age after repeated doses of antenatal cortico-steroids. N Engl J Med 357: 1179-1189, 2007.
13. Deulofeut R, Dudell G, and Sola A. Treatment-by-gender effect when aiming to avoid hyperoxia in preterm infants in the NICU. Acta Paediatr 96: 990-994, 2007.
14. Flohé L and Otting F. Superoxide dismutase assays. Methods Enzymol 105: 93-104, 1984.
15. Flohé L and Güzzler WA. Assays on glutathione peroxidase. Methods Enzymol 105: 114-121, 1984.
16. Forman HJ, Fukuto JM, Miller T, Zhang H, Rinna A, and Levy S. The chemistry of cell signaling by reactive oxygen species and nitrogen species and 4-hydroxynonenal. Arch Biochem Biophys 477: 183-195, 2008.
17. Frank L and Sosenko IRS. Prenatal development of lung antioxidant enzymes in four species. J Pediatr 110: 106-110, 1987.
18. Friel JK, Friesen RW, Harding SV, and Roberts LJ. Evidence of oxidative stress in full-term healthy infants. Pediatr Res 56: 878-882, 2004.
19. Garbrecht MR, Klein JM, Schmidt TJ, and Snyder JM. Glu-cocorticoid metabolism in the human fetal lung: implications for lung development and the pulmonary surfactant system. Biol Neonate 89: 109-119, 2006.
20. Giaccia AJ, Simon MC, and Johnson R. The biology of hypoxia: the role of oxygen sensing in development, normal function and disease. Genes Dev 18: 2138-2194, 2004.
21. Grier DG and Halliday HL. Effects of glucocorticoids on fetal and neonatal lung development. Am J Respir Med 3: 1-9, 2004.
22. Habig WH, Pabst MJ, and Jakoby WB. Glutathione S-transferases: the first enzymatic step in mercapturic acid formation. J Biol Chem 249: 7130-7139, 1974.
23. Halliday H. Surfactant, past, present and future. J Perinatol 28(suppl 1): S47-S56, 2008.
24. Hitchler MJ and Domann FE. An epigenetic perspective on the free radical theory of development. Free Radic Biol Med 43: 1023-1036, 2007.
25. House JT, Schultetus RR, and Gravenstein N. Continuous neonatal evaluation in the delivery room by pulse oximetry. J Clin Monit 3: 96-100, 1987.
26. International Committee for the Classification of Retino-pathy of Prematurity. The International Classification of Retinopathy of Prematurity revisited. Arch Ophthalmol 123: 991-999, 2005.
27. Jobe AH and Bancalari E. Bronchopulmonary dysplasia. Am J Respir Crit Care Med 163: 1723-1729, 2001.
28. Jobe AH. Prenatal corticosteroids: a neonatologist's perspective. NeoReviews 7: e1-e9, 2006.
29. Jobe AH, Hillman N, Polglase G, Kramer BW, Kallapur S, and Pillow J. Injury and inflammation from resuscitation of the preterm infant. Neonatology 94: 190-196, 2008.
30. Liggins GC. Premature parturition after infusion of cortico-trophin or cortisol into foetal lambs. J Endocrinol 42: 323-329, 1968.
31. Liggins GC and Howie RN. A controlled trial of antepartum glucocorticoid treatment for prevention of the respiratory distress syndrome in premature infants. Pediatrics 50: 515-525, 1972.
32. Ledo A, Arduini A, Asensi MA, Sastre J, Escrig R, Brugada M, Aguar M, Saenz P, and Vento M. Human milk enhances antioxidant defenses against hydroxyl radical aggression in preterm infants. Am J Clin Nutr 89: 210-215, 2009.
33. Maltepe E and Saugstad OD. Oxygen in health and disease: regulation of oxygen homeostasis-clinical implications. Pe-diatr Res 65: 261-268, 2009.
34. Marklund SL. Extracellular superoxide dismutase and other superoxide dismutases isoenzymes in tissues from nine mammalian species. Biochem J 222: 649-1255, 1984.
35. Martin JA, Pereda J, Martinez-Lopez I, Escrig R, Miralles V, Pallardo FV, Vina JR, Vento M, Vina J, and Sastre J. Oxidative stress as a signal to up-regulate gamma cystathionase in the fetal-to-neonatal transition in rats. Cell Mol Biol (Noisy-le-grand) 53(suppl): OL1010-OL1017, 2007.
36. McEvoy C, Schilling D, Spitale P, Peters D, O'Malley J, and Durand M. Decreased respiratory compliance in infants 7 days after antenatal steroid therapy. Pediatrics 121: e1032-e1038, 2008.
37. Newnham JP and Jobe AH. Should we be prescribing repeated courses of antenatal corticosteroids? Semin Fetal Neonatal Med 14: 157-163, 2000.
38. Ogueh O and Johnson MR. The metabolic effect of antenatal corticosteroid therapy. Hum Reprod Update 6: 169-176, 2000.
39. Papile LA, Munsick-Bruno G, and Schaefer A. Relationship of cerebral intraventricular hemorrhage and early childhood neurologic handicaps. J Pediatr 103: 273-277, 1983.
40. Pitkanen OM and Hallman M. Evidence for increased oxidative stress in preterm infants eventually developing chronic lung disease. Semin Fetal Neonatal Med 3: 199-205, 1998.
41. Riffenburgh RH. Statistics in medicine. 2nd ed. New York: Academic Press, 2005.
42. Ring AM, Garland JS, Stafeil BR, Carr MH, Peckman GS, and Pircon RA. The effect of a prolonged time interval between antenatal corticosteroid administration and delivery on outcomes in preterm neonates: a cohort study. Am J Obstet Gynecol 196: 457, 2007.
43. Simhan HN and Caritis SN. Prevention of preterm delivery. N Engl J Med 357: 477-487, 2007.
44. Solberg R, Andresen JH, Escrig R, Vento M, and Saugstad OD. Resuscitation of hypoxic newborn piglets with oxygen induces a dose-dependent increase in markers of oxidation. Pediatr Res 62: 559-563, 2007.
45. Tang L, Carey LC, Bi J, Valego N, Sun X, Deibel P, Perrott J, Figueroa JP, Chappell MC, and Rose JC. Gender differences in the effects of antenatal betamethasone exposure on renal function in adult sheep. Am J Physiol Regul Integr Comp Physiol 296: R309-R317, 2009.
46. Tiina MA, Kari OR, Mika S, and Vuokko LK. Expression and development profile of antioxidant enzymes in human lung and liver. Am J Respir Cell Mol Biol 19: 942-949, 1998.
47. Vento M, Asensi M, Sastre J, Garcia-Sala F, Pallardo FV, and Vina J. Resuscitation with room air instead of 100% oxygen prevents oxidative stress in moderately asphyxiated term neonates. Pediatrics 107: 642-647, 2001.
48. Vento M, Asensi M, Sastre J, Lloret A, Garćia-Sala F, Miñana JB, and Vina J. Hyperoxemia caused by resuscitation with pure oxygen may alter intracellular redox status by increasing oxidized glutathione in asphyxiated newly born infants. Semin Perinatol 26: 406-410, 2002.
49. Vento M, Cheung PY, and Aguar M. The first golden minutes of the extremely low gestational age neonate: a gentle approach. Neonatology 95: 286-298, 2008.
50. Vento M, Sastre J, Asensi MA, and Vina J. Room-air resuscitation causes less damage to heart and kidney than 100% oxygen. Am J Respir Crit Care Med 172: 1393-1398, 2005.
51. Vina J, Vento M, Garćia-Sala F, Puertes IR, Gasco E, Sastre J, Asensi M, and Pallardo FV. L-Cysteine and glutathione metabolism are impaired in premature infants due to cystathionase deficiency. Am J Clin Nutr 61: 1067-1069, 1995.
52. Walther FJ, Jobe AH, and Ikegami M. Repetitive prenatal glucocorticoid therapy reduces oxidative stress in the lungs of preterm lambs. J Appl Physiol 85: 273-278, 1998.