Metabolic effects of fructose 1,6-bisphosphate in normoxic and hypoxic states of MG63 osteosarcoma cells

Biomedical Sciences Instrumentation

Volumn 42, Issue , 2006, Pages 120-125

  Adah, Ameze ^a   Benghuzzi, Hamed ^a   Tucci, Michelle ^a   Huang, Derek ^a   Franklin, Laura ^a   Adah, Felix ^a  

^a NONE

Author keywords

Fructose 1,6 bisphosphate; Glycolysis; Hypoxia; MG63 cells; Normoxia

Indexed keywords

BIOASSAY; CELL CULTURE; CYTOLOGY; METABOLISM; OXYGEN; SYNTHESIS (CHEMICAL); ALDEHYDES; FRUCTOSE; INSTRUMENTS; LANDFORMS; OSTEOBLASTS; PATHOLOGY;

FRUCTOSE 1,6-BISPHOSPHATE; HYPOXIA; MG63 CELLS; NORMOXIA;

FRUCTOSE; CELL CULTURE;

FRUCTOSE 1,6 BISPHOSPHATE; GLUTATHIONE; MALONALDEHYDE; OXYGEN;

BONE METABOLISM; CANCER CELL CULTURE; CELL COUNT; CELL DAMAGE; CELL HYPOXIA; CELL PROTECTION; CELL STRAIN MG63; CELL STRUCTURE; CONFERENCE PAPER; CONTROLLED STUDY; CYTOPLASM; DOSE RESPONSE; GLYCOLYSIS; HUMAN; HUMAN CELL; NUCLEOLUS; OSTEOBLAST; OSTEOSARCOMA CELL;

APOPTOSIS; CELL HYPOXIA; CELL LINE; CELL PROLIFERATION; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; FRUCTOSEDIPHOSPHATES; GLYCOLYSIS; HUMANS; OSTEOBLASTS; OXYGEN;

6-BISPHOSPHATE; GLYCOLYSIS; HYPOXIA; MG63 CELLS; NORMOXIA;

EID: 70449112396     PISSN: 00678856     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (13)

1. Ablove RH, Moy OJ, Peimer CA, Severin CM, Sherwin FM (1996). Effect of high-energy phosphates and fee radical scavengers on replant survival in an ishemic extremity model. Microsurgery, 17 (9):481-6.
2. Adah F, (2004). Effect of dual delivery of statin and vancomycin on traumatic bone injury using tracalcium phosphate lysine ceramic in an animal model. Doctoral Dissertation, pages 56-57.
3. Ehrigner WD, Chiang B, Chien S (2001). The uptake and metabolism of fructose-1,6-diphosphate in rat cardiomyocytes. Mol Cell Biochem, 221 91-2): 33-40.
4. Espanol MT, Litt L, Hasegawa K, Chang LH, Macdonald JM, Gregory G, James TL, Chan PH. Fructose-1,6-bisphosphate preserves adenosine troposphere but not intracellular pH during hyposia in respiring neonatal rat brain slices. Anesthesiology, 88 (2):461-72.
5. Gregory GA, Yu AC, Chan PH (1989). Fructose-1,6-bisphosphate protects astrocyte. J Cereb Blood Flow Metab., 9(1): 29-34.
6. Hardin CD, Roberts TM (1994). Metabolism of exogenously applied fructose bisphosphate in hypoxic vascular smooth muscle. Am J Physiol., 267 (6 Pt 2): H2325-32.
7. Juergens TM, Hardin CD (1996). Fructose-1,6-bisphosphate as a metabolic substrate hog ileum smooth muscle during hypoxia. Mol Cell Biochem., 154 (1): 83-93.
8. Long J, Zhang Z, Li X (2002). The protective mechanism of fructose-1,6-diphoischemic brain injury. Zhonghua Yi Zue Za Zhi., 82 (4): 232-5.
9. Sano W, Watanabe F, Tamai H, Furuya E, Mino M (1995). Beneficial effect of fructose-1,6-bisphosphae on mitochondria function during ischemia-reperfusion of rat liver. Gastroenterology. 108 (6): 1785-92.
10. Sola A, Berrios M, Sheldon RA, Ferriero DM, Gregory GA (1996). Fructose-1,6-bisphosphate after hypoxic ischemic injury is protective to the neonatal rat brain. Brain Res., 741 (1-2): 294-9.
11. Sud V, Lindley SG, McDaniel O, Freland AE, Zhang F, Dorsette-Martin W, Bigler SA, Lineaweaver W (2005). Evaluation of fructose 1,6 diphosphate for salvage of ischemic gracilis flaps in rats. J Reconstr Microsurg., 21 (3): 191-6.
12. Webb WR. Metabolic effects of fructose diphosphate in hyposic and ischemic states (1984). J Thorac Cardiovasc Surg., 88 (5 Pt 2):863-6.
13. Wheeler TJ, McCurdy JM, denDekker A, Chien S (2004). Permeability of fructose-1,6-bisphosphate in liposomes and cardiac myocytes. Mol Cell Biochem., 259 (1-2): 105-14.