Fabrication of electrical cell chip for the detection of anticancer drugs and environmental toxicants effect

Biochip Journal

Volumn 3, Issue 2, 2009, Pages 105-112

  El Said, Waleed Ahmed ^a   Yea, Cheol Heon ^a   Kwon, Il Keun ^b   Choi, Jeong Woo ^a  

^a Sogang University   (South Korea)

^b Kyung Hee University   (South Korea)

Author keywords

Anticancer drugs effect; Cell chip; Cyclic voltammetry; HepG2 cell; Potentiometric stripping analysis

Indexed keywords

EID: 70449111259     PISSN: 19760280     EISSN: 20927843     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. Choi, J.W., Park, K.W., Lee, D.B., Lee, W. & Lee, W.H. Cell immobilization using self-assembled synthetic oligopeptide and its application to biological toxicity detection using surface plasmon resonance. Biosens. Bioelectron. 20, 2300-2305 (2005).
2. Brogan, K.L. & Walt D.R. Optical fiber-based sensors: application to chemical biology. Curr. Opin. Chem. Biol. 9, 494-500 (2005).
3. May, K.M., Wang, Y., Bachas, L.G. & Anderson, K.W. Development of a whole-cell-based biosensor for detecting histamine as a model toxin. Anal. Chem. 76, 4156-4161 (2004).
4. Thiébaud, P., Lauer, L., Knoll, W. & Offenhäusser, A. PDMS device for patterned application of microfluids to neuronal cells arranged by microcontact printing. Biosens. Bioelectron. 17, 87-93 (2002).
5. Huang, Y., Sekhon, N.S., Borninski, J., Chen, N. & Rubinsky, B. Instantaneous, quantitative single-cell viability assessment by electrical evaluation of cell membrane integrity with microfabricated devices. Sens. Actuators A 105, 31-39 (2003).
6. Choi, J.W. Cell-based biochip to analyze the effect of anticancer drug. Biotechnol. Bioprocess. Eng. 9, 12-20 (2005).
7. Yea, C.H., Min, J. & Choi, J.W. The fabrication of cell chip for use as bio-sensors. Biochip J. 1, 219-227 (2007).
8. Choi, J.W., Nam, Y.S. & Fujihira, M. Nanoscale fabrication of biomolecular layer and its application to biodevices. Biotechnol. Bioprocess. Eng. 9, 76-85 (2004).
9. Blau, H.M. & Baltimore, D.J. Differentiation requires continuous regulation. J. Cell Biol. 112, 781-783 (1991).
10. Ruoslahti, E. & Obrink, B. Common principles in cell adhesion. Exp. Cell Res. 227, 1-11 (1996).
11. Woolley, D.E., Tetlow, L.C., Adlam, D.J., Gearey, D. & Eden, R.D. Electrochemical monitoring of cell behaviour in vitro: A new technology. Biotechnol. Bioeng. 77, 725-733 (2002).
12. Burlage, R. & Kuo, C.T. Living biosensors for the management and manipulation of microbial consortia. Ann. Rev. Microbiol. 48, 291-309 (1994).
13. Bery, M.N. & Grivell, M.B. An electrochemical description of metabolism. In: Walz, D., Berry, H. & Mi- lazzo, G. Editors, Bioelectrochemistry of cells and tissues, Birkhauser, Basel, Verlag, pp. 134-158 (1995).
14. Thomas, C.A., Jr., Springer, P.A., Loeb, G.E., Berwald-Netter, Y. & Okun, L.M. A miniature microelec- trode array to monitor the bioelectric activity of cultured cells. Exp. Cell Res. 74, 61-66 (1972).
15. Jagner, D. & Graneli, A. Potentiometric stripping analysis. Anal. Chim. Acta 83, 19-26 (1976).
16. Wang, J. et al. Remote electrochemical sensor for trace metal contaminants. Anal. Chem. 67, 1481-1485 (1995).
17. Hatse, S., De Clercq, E. & Balzarini, J. Role of antimetabolites of purine and pyrimidine nucleotide metabolism in tumor cell differentiation. Biochem. Pharmacol. 58, 539-555 (1999).
18. Ji, Y.W., Greg, P. & William, P.V. Cytotoxicity, DNA cross-linking, and DNA single-strand breaks induced by cyclophosphamide in a rat leukemia in vivo. Cancer Chemother. Pharmacol. 31, 381-386 (1993).
19. Ren, S., Kalhorn, T.F. & Slattery, J.T. Inhibition of human aldehyde dehydrogenase 1 by the 4-hydroxy-cyclophosphamide degradation product acrolein. Drug Metab. Dispos. 27, 133-137 (1999).
20. Ru, Q.H., Luo, G.A., Liao, J.J. & Liu, Y. Capillary electrophoretic determination of apoptosis of HeLa cells induced by trichosanthin. J. Chromatogr. A 894, 165-170 (2000).
21. Poirier, M.C., DeCicco, B.T. & Lieberman, M.W. Nonspecific inhibition of DNA repair synthesis by tumor promoters in human diploid fibroblasts damaged with N-acetoxy-2-acetylaminofluorene. Cancer Res. 35,1392-1397 (1975).
22. Freshney, R. Culture of Animal Cells: A Manual of Basic Technique, p. 117, Alan R. Liss, Inc., New York (1987).