Mitochondrial haplotype and phenotype of 13 Chinese families may suggest multi-original evolution of mitochondrial C1494T mutation

Mitochondrion

Volumn 9, Issue 6, 2009, Pages 418-428

  Zhu, Yuhua ^a   Li, Qi ^a,b   Chen, Zhengyi ^c   Kun, Yao ^d   Liu, Lijia ^e   Liu, Xin ^a   Yuan, Huijun ^a   Zhai, Suoqiang ^a   Han, Dongyi ^a   Dai, Pu ^a  

^a CHINESE PLA GENERAL HOSPITAL   (China)

^b CHILDREN S HOSPITAL OF NANJING MEDICAL UNIVERSITY   (China)

^c MASSACHUSETTS EYE AND EAR INFIRMARY   (United States)

^d Fuyang People's Hospital   (China)

^e Mudanjiang First Hospital   (China)

Author keywords

12S rRNA mutation; Aminoglycosides; Haplotype; Hearing loss; Mitochondrial DNA; Penetrance

Indexed keywords

ALANINE TRANSFER RNA; AMINOGLYCOSIDE ANTIBIOTIC AGENT; MITOCHONDRIAL DNA; RNA 12S; TYROSINE TRANSFER RNA;

ARTICLE; AUDIOMETRY; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; DNA FRAGMENTATION; DNA POLYMORPHISM; DNA SEQUENCE; FEMALE; GENE; GENE EXPRESSION; GENE LOCATION; GJB2 GENE; HAPLOTYPE; HEARING LOSS; HUMAN; MALE; MITOCHONDRIAL GENOME; MOLECULAR EVOLUTION; MUTATIONAL ANALYSIS; NUCLEOTIDE SEQUENCE; ONSET AGE; PEDIGREE; PENETRANCE; PHENOTYPE; PRIORITY JOURNAL; SEQUENCE ANALYSIS;

AGE FACTORS; AMINOGLYCOSIDES; ANTI-BACTERIAL AGENTS; ASIAN CONTINENTAL ANCESTRY GROUP; CHINA; DNA, MITOCHONDRIAL; DNA, RIBOSOMAL; FEMALE; HAPLOTYPES; HEARING LOSS, SENSORINEURAL; HEREDITY; HUMANS; MALE; PHENOTYPE; POINT MUTATION; POLYMORPHISM, GENETIC; SEQUENCE ANALYSIS, DNA; SEVERITY OF ILLNESS INDEX;

EID: 70449109181     PISSN: 15677249     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mito.2009.07.006     Document Type: Article

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