Nuclear location of minor capsid protein L2 is required for expression of a reporter plasmid packaged in HPV51 pseudovirions

Virology

Volumn 394, Issue 2, 2009, Pages 259-265

  Kondo, Kazunari ^a,b   Ishii, Yoshiyuki ^a   Mori, Seiichiro ^a   Shimabukuro, Shiho ^a   Yoshikawa, Hiroyuki ^b   Kanda, Tadahito ^a  

^a NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

^b UNIVERSITY OF TSUKUBA   (Japan)

Author keywords

HPV51; L2 function; Pseudovirion

Indexed keywords

CAPSID PROTEIN; CAPSID PROTEIN L1; CAPSID PROTEIN L2; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL STRAIN HEK293; CELLULAR DISTRIBUTION; CONTROLLED STUDY; GENE SEQUENCE; HUMAN; HUMAN CELL; HUMAN PAPILLOMAVIRUS 51; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; NUCLEOTIDE SEQUENCE; PLASMID; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PSEUDOVIRION; VIRION; VIRUS ISOLATION; VIRUS MORPHOLOGY; VIRUS STRAIN; WART VIRUS;

AMINO ACID SEQUENCE; CAPSID PROTEINS; CELL LINE; CELL NUCLEUS; CYTOPLASM; GENE EXPRESSION; GENES, REPORTER; GENES, VIRAL; HUMANS; MOLECULAR SEQUENCE DATA; NUCLEAR LOCALIZATION SIGNALS; ONCOGENE PROTEINS, VIRAL; PAPILLOMAVIRIDAE; PLASMIDS; SEQUENCE HOMOLOGY, AMINO ACID; SPECIES SPECIFICITY; VIRION; VIRUS ASSEMBLY;

MIRIDAE;

EID: 70449109171     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2009.08.034     Document Type: Article

References (18)

1. Buck C.B., Pastrana D.V., Lowy D.R., and Schiller J.T. Efficient intracellular assembly of papillomaviral vectors. J. Virol. 78 (2004) 751-757
2. Buck C.B., Pastrana D.V., Lowy D.R., and Schiller J.T. Generation of HPV pseudovirions using transfection and their use in neutralization assays. Methods Mol. Med. 119 (2005) 445-462
3. Collier B., Öberg D., Zhao X., and Schwartz S. Specific inactivation of inhibitory sequences in the 5′ end of the human papillomavirus type 16 L1 open reading frame results in production of high levels of L1 protein in human epithelial cells. J. Virol. 76 (2002) 2739-2752
4. Darshan M.S., Lucchi J., Harding E., and Moroianu J. The L2 minor capsid protein of human papillomavirus type 16 interacts with a network of nuclear import receptors. J. Virol. 78 (2004) 12179-12188
5. Day P.M., Baker C.C., Lowy D.R., and Schiller J.T. Establishment of papillomavirus infection is enhanced by promyelocytic leukemia protein (PML) expression. Proc. Natl. Acad. Sci. U. S. A. 101 (2004) 14252-14257
6. Finnen R.L., Erickson K.D., Chen X.S., and Garcea R. Interaction between papillomavirus L1 and L2 capsid proteins. J.Virol. 77 (2003) 4818-4826
7. Howley P.M., and Lowy D.R. Papillomaviruses and their replication. In: Lnipe D.M., and Howley P.M. (Eds). Fields Virology. 4th ed Vol. 2 (2001), Lippincott, Williams and Wilkins, Philadelphia 2197-2229
8. Kondo K., Ishii Y., Ochi H., Matsumoto T., Yoshikawa H., and Kanda T. Neutralization of HPV16, 18, 31, and 58 pseudovirions with antisera induced by immunizing rabbits with synthetic peptides representing segments of the HPV16 minor capsid protein L2 surface region. Virology 358 (2007) 266-272
9. Lungu O., Nuovo G.J., Crum C.P., and Silverstein S.J. Biologic properties and nucleotides sequence analysis of human papillomavirus type 51. J. Virol. 65 (1991) 4216-4225
10. Matsukura T., and Sugase M. Identification of genital human papillomavirus in cervical biopsy specimens: segregation of specific virus types in specific clinicopathologic legions. Int. J. Cancer 61 (1995) 13-22
11. Nuovo G.J., Crum C.P., De Villiers E.M., Levine R.U., and Silverstein S.J. Isolation of a novel human papillomavirus (type 51) from a cervical condyloma. J. Virol 62 (1988) 1452-1455
12. Pereira R., Hitzeroth I.I., and Rybicki E.P. Insights into the role and function of L2, the minor capsid protein of papillomaviruses. Arch. Virol. 154 (2009) 187-197
13. Sapp M., and Selinka H.C. Pseudovirions as specific tools for investigation of virus interactions with cells. Methods Mol. Biol. 292 (2005) 197-212
14. Sokolowski M., Tan W., Jellne M., and Schwartz S. mRNA instability elements in the human papillomavirus type 16 L2 coding region. J. Virol. 72 (1998) 1504-1515
15. Stauffer Y., Raj K., Masternak K., and Beard P. Infectious human papillomavirus type18 pseudovirions. J. Mol. Biol. 283 (1998) 529-536
16. Sun X.Y., Frazer I., Müller M., Gissmann L., and Zhou J. Sequences required for the nuclear targeting and accumulation of human papillomavirus type 6B L2 protein. Virology 213 (1995) 321-327
17. Unckell F., Streeck R.E., and Sapp M. Generation and neutralization of pseudovirions of human papillomavirus type33. J. Virol. 71 (1997) 2934-2939
18. Zhou J., Doorbar J., Sun X.Y., Crawford L.V., McLean C.S., and Frazer I.H. Identification of the nuclear localization signal of human papillomavirus type 16 L1 protein. Virology 185 (1991) 625-632