Capturing complex protein gradients on biomimetic hydrogels for cell-based assays

Advanced Functional Materials

Volumn 19, Issue 21, 2009, Pages 3411-3419

  Cosson, Steffen ^a   Kobel, Stefan A ^a   Lutolf, Matthias P ^a  

^a EPFL   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

BIOMIMETIC HYDROGELS; CELL CULTURE SUBSTRATE; CELL MIGRATION; CELL TYPES; CELL-BASED ASSAYS; COMPLEX GRADIENT; CONCENTRATION OF; EXTRACELLULAR MATRICES; FIBRONECTIN FRAGMENTS; FUSION PROTEINS; HUMAN FIBROBLAST; HYDROGEL SURFACES; MICROFLUIDIC CHIP; MIGRATION RATES; NEUTRAVIDIN; ORTHOGONALITY; TIME-LAPSE MICROSCOPY;

ANIMAL CELL CULTURE; BIOCHIPS; BIOMIMETIC MATERIALS; BIOMIMETICS; ETHYLENE; ETHYLENE GLYCOL; FLUIDIC DEVICES; HYDROGELS; MICROFLUIDICS; POLYETHYLENE GLYCOLS; POLYETHYLENE OXIDES; PROTEINS;

CELL CULTURE;

EID: 70449107589     PISSN: 1616301X     EISSN: 16163028     Source Type: Journal    
DOI: 10.1002/adfm.200900968     Document Type: Article

References (39)

1. P. P. L. Tam, D. A. F. Loebel, Nat. Rev. Genet. 2007, 8, 368.
2. C. E. Murry, G. Keller, Cell 2008, 132, 661.
3. F. Ramirez, D. B. Rifkin, Matrix Biol. 2003, 22, 101.
4. T. M. Keenan, A. Folch, Lab Chip 2008, 8, 34.
5. S. Boyden, J. Exp. Med. 1962, 115, 453.
6. E. Delamarche, A. Bernard, H. Schmid, A. Bietsch, B. Michel, H. Biebuyck, J. Am. Chem. Soc. 1998, 120, 500.
7. K. A. Fosser, R. G. Nuzzo, Anal. Chem. 2003, 75, 5775.
8. W. Georgescu, J. Jourquin, L. Estrada, A. R. A. Anderson, V. Quaranta, J. P. Wikswo, Lab Chip 2008, 8, 238.
9. R. C. Gunawan, E. R. Choban, J. E. Conour, J. Silvestre, L. B. Schook, H. R. Gaskins, D. E. Leckband, P. J. A. Kenis, Langmuir 2005, 21, 3061.
10. A. C. Von Philipsborn, S. Lang, A. Bernard, J. Loeschinger, C. David, D. Lehnert, M. Bastmeyer, F. Bonhoeffer, Nat. Protoc. 2006, 1, 1322.
11. C. J. Wang, X. Li, B. Lin, S. Shim, G. L. Ming, A. Levchenko, Lab Chip 2008, 8, 227.
12. J. Genzer, R. R. Bhat, Langmuir 2008, 24, 2294.
13. D. E. Discher, P. Janmey, Y. L. Wang, Science 2005, 310, 1139.
14. J. L. Drury, D. J. Mooney, Biomaterials 2003, 24, 4337.
15. J. A. Burdick, A. Khademhosseini, R. Langer, Langmuir 2004, 20, 5153.
16. J. Kopecek, J. Y. Yang, Polym. Int. 2007, 56, 1078.
17. J. A. Hubbell, M. P. Lutolf, Nat. Biotechnol. 2005, 23, 47.
18. M. P. Lutolf, J. A. Hubbell, Biomacromolecules 2003, 4, 713.
19. V. Trujillo, J. Kim, R. C. Hayward, Soft Matter 2008, 4, 564.
20. M. Cordey, M. Limacher, S. Kobel, V. Taylor, M. P. Lutolf, Stem Cells 2008, 26, 2586.
21. S. Kobel, M. Limacher, S. Gobaa, T. Laroche, M. P. Lutolf, Langmuir 2009, 25, 8774.
22. S. K. W. Dertinger, D. T. Chiu, N. L Jeon, G. M. Whitesides, Anal. Chem. 2001, 73, 1240.
23. N. L. Jeon, S. K. W. Dertinger, D. T. Chiu, I. S. Choi, A. D. Stroock, G. M. Whitesides, Langmuir 2000, 16, 8311.
24. T. Braschler, L. Metref, R. Zvitov-Marabi, H. van Lintel, N. Demierre, J. Theytaz, P. Renaud, Lab Chip 2007, 7, 420.
25. I. Meyvantsson, D. J. Beebe, Annu. Rev. Anal. Chem. 2008, 1, 423.
26. G. M. Walker, H. C. Zeringue, D. J. Beebe, Lab Chip 2004, 4, 91.
27. P. Y. Andrew Evan Kamholz, Biophys. J. 2001, 80, 155.
28. G. M. Walker, J. Q. Sai, A. Richmond, M. Stremler, C. Y. Chung, J. P. Wikswo, Lab Chip 2005, 5, 611.
29. M. M. Martino, M. Mochizuki, D. A. Rothenfluh, S. A. Rempel, J. A. Hubbell, T. H. Barker, Biomaterials 2009, 30, 1089.
30. P. A. Dimilla, J. A. Stone, J. A. Quinn, S. M. Albelda, D. A. Lauffenburger, J. Cell Biol. 1993, 122, 729.
31. S. P. Palecek, J. C. Loftus, M. H. Ginsberg, D. A. Lauffenburger, A. F. Horwitz, Nature 1997, 385, 537.
32. G. P. Raeber, M. P. Lutolf, J. A. Hubbell, Biophys J. 2005, 89, 1374.
33. R. C. Gunawan, J. Silvestre, H. R. Gaskins, P. J. A. Kenis, D. E. Leckband, Langmuir 2006, 22, 4250.
34. L. G. Griffith, M. A. Swartz, Nat. Rev. Mol. Cell Bio. 2006, 7, 211.
35. S. A. DeLong, J. J. Moon, J. L. West, Biomaterials 2005, 26, 3227.
36. S. Morgenthaler, C. Zink, N. D. Spencer, Soft Matter 2008, 4, 419.
37. D. B. Hibbert, J. J. Gooding, P. Erokhin, Langmuir 2002, 18, 1770.
38. J. Crank, The Mathematics of Diffusion, 2nd ed. Oxford University Press, New York, 1975.
39. L. Huang, P. K. Nair, M. T. S. Nair, R. A. Zingaro, E. A. Meyers, Thin Solid Films 1995, 268, 49.