SdrX, a serine-aspartate repeat protein expressed by Staphylococcus capitis with collagen VI binding activity

Infection and Immunity

Volumn 72, Issue 11, 2004, Pages 6237-6244

  Liu, Yule ^a   Ames, Brenda ^a   Gorovits, Elena ^a   Prater, Bradley D ^a   Syribeys, Peter ^a   Vernachio, John H ^a   Patti, Joseph M ^a  

^a Inhibitex Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTIC ACID; BACTERIAL PROTEIN; COLLAGEN TYPE 6; METHIONYLSERYLCYSTEINYLARGINYLALANYLMETHIONYLMETHIONINE; PROTEIN SDRX; RECOMBINANT PROTEIN; SERINE; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL GENE; BACTERIAL GENOME; BINDING AFFINITY; FLOW CYTOMETRY; GENE EXPRESSION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; SDRX GENE; SOUTHERN BLOTTING; STAPHYLOCOCCUS; STAPHYLOCOCCUS CAPITIS; STAPHYLOCOCCUS INFECTION; VERY LOW BIRTH WEIGHT; WESTERN BLOTTING;

ADHESINS, BACTERIAL; AMINO ACID SEQUENCE; ASPARTIC ACID; BACTERIAL PROTEINS; CLONING, MOLECULAR; COLLAGEN; HUMANS; INFANT, NEWBORN; MEMBRANE PROTEINS; MOLECULAR SEQUENCE DATA; SERINE; STAPHYLOCOCCUS;

EID: 7044274379     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.72.11.6237-6244.2004     Document Type: Article

References (32)

1. Allignet, J., S. Aubert, K. G. Dyke, and N. El Solh. 2001. Staphylococcus caprae strains carry determinants known to be involved in pathogenicity: a gene encoding an autolysin-binding fibronectin and the ica operon involved in biofilm formation. Infect. Immun. 69:712-718.
2. Bidanset, D. J., C. Guidry, L. C. Rosenberg, H. U. Choi, R. Timpl, and M. Hook. 1992. Binding of the proteoglycan decorin to collagen type VI. J. Biol. Chem. 267:5250-5256.
3. Bonaldo, P., V. Russo, F. Bucclotti, R. Doliana, and A. Colombatti. 1990. Structural and functional features of the alpha 3 chain indicate a bridging role for chicken collagen VI in connective tissues. Biochemistry 29:1245-1254.
4. Burg, M. A., E. Tillet, R. Timpl, and W. B. Stallcup. 1996. Binding of the NG2 proteoglycan to type VI collagen and other extracellular matrix molecules. J. Biol. Chem. 271:26110-26116.
5. Engel, J., H. Furthmayr, E. Odermatt, H. von der Mark, M. Aumailley, R. Fleischmajer, and R. Timpl. 1985. Structure and macromolecular organization of type VI collagen. Ann. N. Y. Acad. Sci. 460:25-37.
6. Furthmayr, H., H. Wiedemann, R. Timpl, E. Odermatt, and J. Engel. 1983. Electron-microscopical approach to a structural model of intima collagen. Biochem. J. 211:303-311.
7. Hall, A. E., P. J. Domanski, P. R. Patel, J. H. Vernachio, P. J. Syribeys, E. L. Gorovits, M. A. Johnson, J. M. Ross, J. T. Hutchins, and J. M. Patti. 2003. Characterization of a protective monoclonal antibody recognizing Staphylococcus aureus MSCRAMM protein clumping factor A. Infect. Immun. 71:6864-6870.
8. Hartford, O., L. O'Brien, K. Schofield, J. Wells, and T. J. Foster. 2001. The Fbe (SdrG) protein of Staphylococcus epidermidis HB promotes bacterial adherence to fibrinogen. Microbiology 147:2545-2552.
9. Hartford, O., P. Francois, P. Vaudaux, and T. J. Foster. 1997. The dipeptide repeat region of the fibrinogen-binding protein (clumping factor) is required for functional expression of the fibrinogen-binding domain on the Staphylococcus aureus cell surface. Mol. Microbiol. 25:1065-1076.
10. Hell, W., H. G. Meyer, and S. G. Gatermann. 1998. Cloning of aas, a gene encoding a Staphylococcus saprophyticus surface protein with adhesive and autolytic properties. Mol. Microbiol. 29:871-881.
11. Jobsis, G. J., H. Keizers, J. P. Vreijling, M. de Visser, M. C. Speer, R. A. Wolterman, F. Baas, and P. A. Bolhuis. 1996. Type VI collagen mutations in Bethlem myopathy, an autosomal dominant myopathy with contractures. Nat. Genet. 14:113-115.
12. Josefsson, E., K. W. McCrea, D. Ni Eidhin, D. O'Connell, J. Cox, M. Hook, and T. J. Foster. 1998. Three new members of the serine-aspartate repeat protein multigene family of Staphylococcus aureus. Microbiology 144(Pt. 12):3387-3395.
13. Josefsson, E., O. Hartford, L. O'Brien, J. M. Patti, and T. Foster. 2001. Protection against experimental Staphylococcus aureus arthritis by vaccination with clumping factor A, a novel virulence determinant. J. Infect. Dis. 184:1572-1580.
14. Keene, D. R., E. Engvall, and R. W. Glanville. 1995. Ultrastructure of type VI collagen in human skin and cartilage suggests an anchoring function for this filamentous network. J. Cell Biol. 107:1995-2006.
15. Kuo, H.-J. C. L. Maslen, D. R. Keene, and R. W. Glanville. 1997. Type VI collagen anchors endothelial basement membranes by interacting with type IV collagen. J. Biol. Chem. 272:26522-26529.
16. Lamande, S. R., J. F. Bateman, W. Hutchison, R. J. M. Gardner, S. P. Bower, E. Byrne, and H.-H. M. Dahl. 1998. Reduced collagen VI causes Bethlem myopathy: a heterozygous COL6A1 nonsense mutation results in mRNA decay and functional haploinsufficiency. Hum. Mol. Genet. 7:981-989.
17. Mazmanian, S. K., G. Liu, H. Ton-That, and O. Schneewind. 1999. Staphylococcus aureus sortase, an enzyme that anchors surface proteins to the cell wall. Science 285:760-763.
18. McCrea, K. W., O. Hartford, S. Davis, D. N. Eidhin, G. Lina, P. Speziale, T. J. Foster, and M. Hook. 2000. The serine-aspartate repeat (Sdr) protein family in Staphylococcus epidermidis. Microbiology 146:1535-1546.
19. McDevitt, D., P. Francois, P. Vaudaux, and T. J. Foster. 1994. Molecular characterization of the clumping factor (fibrinogen receptor) of Staphylococcus aureus. Mol. Microbiol. 11:237-248.
20. McDevitt, D., P. Vaudaux, and T. J. Foster. 1992. Genetic evidence that bound coagulase of Staphylococcus aureus is not clumping factor. Infect. Immun. 60:1514-1523.
21. Ni Eidhin, D., S. Perkins, P. Francois, P. Vaudaux, M. Hook, and T. J. Foster. 1998. Clumping factor B (ClfB), a new surface-located fibrinogen-binding adhesin of Staphylococcus aureus. Mol. Microbiol. 30:245-257.
22. 2+-dependent inhibitory site. J. Biol. Chem. 273:6821-6829.
23. Pan, T.-C., R.-Z. Zhang, M. A. Pericak-Vance, R. Tandan, T. Fries, J. Stajich, K. Viles, J. M. Vance, M.-L. Chu, and M. C. Speer. 1998. Missense mutation in a von Willebrand factor type A domain of the α3(VI) collagen gene (COL6A3) in a family with Bethlem myopathy. Hum. Mol. Genet. 7:807-812.
24. Patti, J. M., and M. Hook. 1994. Microbial adhesins recognizing extracellular matrix macromolecules. Curr. Opin. Cell Biol. 6:752-758.
25. Patti, J. M., B. A. Aleen, M. J. McGavin, and M. Hook. 1994. MSCRAMM-mediated adherence of microorganisms to host tissues. Annu. Rev. Microbiol. 45:585-617.
26. Pfaff, M., M. Aumailley, U. Specks, J. Knolle, H. G. Zerwes, and R. Timpl. 1993. Integrin and Arg-Gly-Asp dependence of cell adhesion to the native and unfolded triple helix of collagen type VI. Exp. Cell Res. 206:167-176.
27. Savolainen, K., L. Paulin, B. Westerlund-Wikström, T. J. Foster, T. K. Korhonen, and P. Kuusela. 2001. Expression of pls, a gene closely associated with the mecA gene of methicillin-resistant Staphylococcus aureus, prevents bacterial adhesion in vitro. Infect. Immun. 69:3013-3020.
28. Schneewind, O., D. Mihaylova-Petkov, and P. Model. 1993. Cell wall sorting signals in surface proteins of gram-positive bacteria. EMBO J. 12:4803-4811.
29. Schneewind, O., A. Fowler, and K. F. Faull. 1995. Structure of the cell wall anchor of surface proteins in Staphylococcus aureus. Science 268:103-106.
30. Stoll, B. J., N. Hansen, A. A. Fanaroff, L. L. Wright, W. A. Carlo, R. A. Ehrenkranz, J. A. Lemons, E. F. Donovan, A. R. Stark, J. E. Tyson, W. Oh, C. R. Bauer, S. B. Korones, S. Shankaran, A. R. Laptook, D. K. Stevenson, L. A. Papile, and W. K. Poole. 2002. Late-onset sepsis in very low birth weight neonates: the experience of the NICHD Neonatal Research Network. Pediatrics 110:285-291.
31. Van Der Zwet, W. C., Y. J. Debets-Ossenkopp, E. Reinders, M. Kapi, P. H. M. Savelkoul, R. M. Van Elburg, K. Hiramatsu, and C. M. J. E. Vandenbroucke-Grauls. 2002. Nosocomial spread of a Staphylococcus capitis strain with heteroresistance to vancomycin in a neonatal intensive care unit. J. Clin. Microbiol. 40:2520-2525.
32. Vernachio, J., A. S. Bayer, T. Le, Y.-L. Chai, B. Prater, A. Scnhneider, B. Ames, P. Syribeys, J. Robbins, and J. M. Patti. 2003. Anti-clumping factor A immunoglobulin reduces the duration of methicillin-resistant Staphylococcus aureus bacteremia in an experimental model of infective endocarditis. Antimicrob. Agents Chemother. 47:3400-3406.