Montelukast and airway remodeling in children with chronic persistent asthma: An open study

Pediatric Allergy and Immunology

Volumn 15, Issue 5, 2004, Pages 472-473

  Pifferi, Massimo ^a   Caramella, Davide ^a   Ragazzo, Vincenzo ^a   De Marco, Emanuela ^a   Pietrobelli, Angelo ^b   Boner, Attilio L ^b  

^a UNIVERSITY OF PISA   (Italy)

^b UNIVERSITY OF VERONA   (Italy)

Author keywords

Children; Chronic asthma; Eosinophil cationic protein; High resolution computerized tomography; Residual volume

Indexed keywords

BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; CORTICOSTEROID; FLUTICASONE PROPIONATE; LEUKOTRIENE RECEPTOR BLOCKING AGENT; MONTELUKAST; SALMETEROL;

AIRWAY; ARTICLE; ASTHMA; CHILD; CHRONIC DISEASE; CLINICAL ARTICLE; CLINICAL TRIAL; FOLLOW UP; FORCED EXPIRATORY VOLUME; HIGH RESOLUTION COMPUTER TOMOGRAPHY; HUMAN; LUNG FUNCTION; OPEN STUDY; PRIORITY JOURNAL; SCORING SYSTEM; TREATMENT OUTCOME;

ACETATES; ALBUTEROL; ANDROSTADIENES; ANTI-ASTHMATIC AGENTS; ASTHMA; BRONCHODILATOR AGENTS; CHILD; CHRONIC DISEASE; DRUG THERAPY, COMBINATION; FOLLOW-UP STUDIES; HUMANS; LUNG; QUINOLINES; RESPIRATORY FUNCTION TESTS;

EID: 7044273936     PISSN: 09056157     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1399-3038.2004.00184.x     Document Type: Article

References (9)

1. PIFFERI M, CARAMELLA D, RAGAZZO V, PIETROBELLI A, BONER AL. Low-density areas on high-resolution computed tomograms in chronic pediatric asthma. J Pediatr 2002: 141: 104-8.
2. SKOLD CM, LIU XD, ZHU YK, et al. Glucocorticoids augment fibroblast-mediated contraction of collagen gels by inhibition of endogenous PGE production. Proc Assoc Am Phys 1999: 111: 249-58.
3. BOULET LP, TURCOTTE H, LAVIOLETTE M, et al. Airway hyperresponsiveness, inflammation, and subepithelial collagen deposition in recently diagnosed versus long-standing mild asthma. Influence of inhaled corticosteroids. Am J Respir Crit Care Med 2000: 162: 1308-13.
4. HENDERSON WR, TANG L-O, CHU S-J, et al. A role for cysteinyl leukotrienes in airway remodeling in a mouse asthma model. Am J Respir Crit Care Med 2002: 165: 108-16.
5. LEMANSKE RF. Origin and treatment of airway inflammation in childhood asthma. Pediatr Pulmonol 2001: S21: 17-25.
6. WILBORN J, BAILIE M, COFFEY M, BURDICK M, STRIETER R, PETERS-GOLDEN M. Constitutive activation of 5-lipoxygenase in the lungs of patients with idiopathic pulmonary fibrosis. J Clin Invest 1996: 97: 1827-36.
7. JEFFERY P. Inflammation and remodeling in the adult and child with asthma. Pediatr Pulmonol 2001: S21: 3-16.
8. PIACENTINI GL, PERONI DG, DEL GIUDICE MM, et al. Effect of montelukast on exhaled NO in asthmatic children exposed to relevant allergens. Pediatr Allergy Immunol 2002: 13: 137-9.
9. PERONI DG, PIACENTINI GL, RESS M, et al. Time efficacy of a single dose of montelukast on exercise-induced asthma in children. Pediatr Allergy Immunol 2002: 13: 434-7.