RGD-mutants of B-lymphotropic polyomavirus capsids specifically bind to αvβ3 integrin

Archives of Virology

Volumn 149, Issue 10, 2004, Pages 1877-1896

  Langner, J ^a   Neumann, B ^a   Goodman, S L ^b   Pawlita, M ^a  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^b MERCK KGAA   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHAVBETA5 INTEGRIN; ARGINYL-GLYCYL-ASPARTIC ACID; ARGINYLGLYCYLASPARTIC ACID; CAPSID PROTEIN; FIBRINOGEN RECEPTOR; INTEGRIN; OLIGOPEPTIDE; VIRUS RECEPTOR; VITRONECTIN RECEPTOR; VP1 PROTEIN, POLYOMAVIRUS;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; METABOLISM; MISSENSE MUTATION; MOLECULAR GENETICS; POLYOMA VIRUS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN MOTIF; SIMIAN VIRUS 40; VIRUS ASSEMBLY;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; CAPSID PROTEINS; INTEGRIN ALPHAVBETA3; INTEGRINS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION, MISSENSE; OLIGOPEPTIDES; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; POLYOMAVIRUS; PROTEIN BINDING; PROTEIN CONFORMATION; RECEPTORS, VIRUS; RECEPTORS, VITRONECTIN; SIMIAN VIRUS 40; VIRUS ASSEMBLY;

AFRICAN GREEN MONKEY POLYOMAVIRUS; INSECTA; POLYOMAVIRUS; UNIDENTIFIED BACULOVIRUS;

EID: 7044272540     PISSN: 03048608     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00705-004-0374-z     Document Type: Article

References (55)

1. Barouch DH, Harrison SC (1994) Interactions among the major and minor coat proteins of polyomavirus. J Virol 68: 3982-3989
2. Baxt B, Becker Y (1990) The effect of peptides containing the arginine-glycine-aspartic acid sequence on the adsorption of foot-and-mouth disease virus to tissue culture cells. Virus Genes 4: 73-83
3. Chambers MA, Dougan G, Newman J, Brown F, Crowther J, Mould AP, Humphries MJ, Francis MJ, Clarke B, Brown AL, Rowlands D (1996) Chimeric hepatitis B virus core particles as probes for studying peptide-integrin interactions. J Virol 70: 4045-4052
4. Chang KH, Day C, Walker J, Hyypia T, Stanway G (1992) The nucleotide sequences of wild-type coxsackievirus A9 strains imply that an RGD motif in VP1 is functionally significant. J Gen Virol 73: 621-626
5. Chen XS, Stehle T, Harrison SC (1998) Interaction of polyomavirus internal protein VP2 with the major capsid protein VP1 and implications for participation of VP2 in viral entry. EMBO J 17: 3233-3240
6. Coppolino MG, Dedhar S (2000) Bi-directional signal transduction by integrin receptors. Int J Biochem Cell Biol 32: 171-188
7. Cripe TP, Dunphy EJ, Holub AD, Saini A, Vasi NH, Mahller YY, Collins MH, Snyder JD, Krasnykh V, Curiel DT, Wickham TJ, DeGregori J, Bergelson JM, Currier MA (2001) Cancer Res 61: 2953-2960
8. Curley GP, Blum H, Humphries MJ (1999) Integrin antagonists. Cell Mol Life Sci 56: 427-441
9. Dechantsreiter MA, Planker E, Matha B, Lohof E, Holzemann G, Jonczyk A, Goodman SL, Kessler H (1999) N-Methylated cyclic RGD peptides as highly active and selective alpha(V)beta(3) integrin antagonists. J Med Chem 42: 3033-3040
10. DeNardo SJ, Burke PA, Leigh BR, O'Donnell RT, Miers LA, Kroger LA, Goodman SL, Matzku S, Jonczyk A, Lamborn KR, DeNardo GL (2000) Neovascular targeting with cyclic RGD peptide (cRGDf-ACHA) to enhance delivery of radioimmunotherapy. Cancer Biother Radiopharm 15: 71-79
11. Dmitriev I, Krasnykh V, Miller CR, Wang M, Kashentseva E, Mikheeva G, Belousova N, Curiel DT (1998) An adenovirus vector with genetically modified fibers demonstrates expanded tropism via utilization of a coxsackievirus and adenovirus receptor-independent cell entry mechanism. J Virol 72: 9706-9713
12. Forstova J, Krauzewicz N, Wallace S, Street AJ, Dilworth SM, Beard S, Griffin BE (1993) Cooperation of structural proteins during late events in the life cycle of polyomavirus. J Virol 67: 1405-1413
13. Fox G, Parry NR, Barnett PV, McGinn B, Rowlands DJ, Brown F (1989) The cell attachment site on foot-and-mouth disease virus includes the amino acid sequence RGD (arginine-glycine-aspartic acid). J Gen Virol 70: 625-637
14. Franke WW, Luder MR, Kartenbeck J, Zerban H, Keenan TW (1976) Involvement of vesicle coat material in casein secretion and surface regeneration. J Cell Biol 69: 173-195
15. Garcia MI, Perez M, Caruso M, Sthandier O, Ferreira R, Cermola M, Macchia C, Amati P (2000) A mutation in the DE loop of the VP1 protein that prevents polyomavirus transcription and replication. Virology 272: 293-301
16. Girod A, Ried M, Wobus C, Lahm H, Leike K, Kleinschmidt J, Deleage G, Hallek M (1999) Genetic capsid modifications allow efficient re-targeting of adeno-associated virus type 2. Nat Med 5: 1052-1056
17. Goldmann C, Petry H, Frye S, Ast O, Ebitsch S, Jentsch KD, Kaup FJ, Weber F, Trebst C, Nisslein T, Hunsmann G, Weber T, Luke W (1999) Molecular cloning and expression of major structural protein VP1 of the human polyomavirus JC virus: formation of virus-like particles useful for immunological and therapeutic studies. J Virol 73: 4465-4469
18. Haun G, Keppler OT, Bock CT, Herrmann M, Zentgraf H, Pawlita M (1993) The cell surface receptor is a major determinant restricting the host range of the B-lymphotropic papovavirus. J Virol 67: 7482-7492
19. Herrmann M, Oppenlander M, Pawlita M (1995) Fast and high-affinity binding of B-lymphotropic papovavirus to human B-lymphoma cell lines. J Virol 69: 6797-6804
20. Higgins DG, Sharp PM (1989) Fast and sensitive multiple sequence alignments on a microcomputer. Comput Appl Biosci 5: 151-153
21. Keppler OT, Moldenhauer G, Oppenlander M, Schwartz-Albiez R, Berger EG, Funderud S, Pawlita M (1992) Human Golgi beta-galactoside alpha-2,6- sialyltransferase generates a group of sialylated B lymphocyte differentiation antigens. Eur J Immunol 22: 2777-2781
22. Keppler OT, Herrmann M, Oppenlander M, Meschede W, Pawlita M (1994) Regulation of susceptibility and cell surface receptor for the B-lymphotropic papovavirus by N glycosylation. J Virol 68: 6933-6939
23. Keppler OT, Stehling P, Herrmann M, Kayser H, Grunow D, Reutter W, Pawlita M (1995) Biosynthetic modulation of sialic acid-dependent virus-receptor interactions of two primate polyoma viruses. J Biol Chem 270: 1308-1314
24. Keppler OT, Hinderlich S, Langner J, Schwartz-Albiez R, Reutter W, Pawlita M (1999) UDP-GlcNAc 2-epimerase: a regulator of cell surface sialylation. Science 284: 1372-1376
25. Keppler OT, Peter ME, Hinderlich S, Moldenhauer G, Stehling P, Schmitz I, Schwartz-Albiez R, Reutter W, Pawlita M (1999) Differential sialylation of cell surface glycoconjugates in a human B lymphoma cell line regulates susceptibility for CD95 (APO-1/Fas)-mediated apoptosis and for infection by a lymphotropic virus. Glycobiology 9: 557-569
26. Koizumi N, Mizuguchi H, Hosono T, Ishii-Watabe A, Uchida E, Utoguchi N, Watanabe Y, Hayakawa T (2001) Efficient gene transfer by fiber-mutant adenoviral vectors containing RGD peptide. Biochim Biophys Acta 1568: 13-20
27. Kosukegawa A, Arisaka F, Takayama M, Yajima H, Kaidow A, Handa H (1996) Purification and characterization of virus-like particles and pentamers produced by the expression of SV40 capsid proteins in insect cells. Biochim Biophys Acta 1290: 37-45
28. Kraft S, Diefenbach B, Mehta R, Jonczyk A, Luckenbach GA, Goodman SL (1999) Definition of an unexpected ligand recognition motif for alphav beta6 integrin. J Biol Chem 274: 1979-1985
29. Kyhse-Andersen J (1984) Electroblotting of multiple gels: a simple apparatus without buffer tank for rapid transfer of proteins from polyacrylamide to nitrocellulose. J Biochem Biophys Methods 10: 203-209
30. Leahy DJ, Aukhil I, Erickson HP (1996) 2.0 A crystal structure of a four-domain segment of human fibronectin encompassing the RGD loop and synergy region. Cell 84: 155-164
31. Liddington RC, Yan Y, Moulai J, Sahli R, Benjamin TL, Harrison SC (1991) Structure of simian virus 40 at 3.8-A resolution. Nature 354: 278-284
32. Mathias P, Wickham T, Moore M, Nemerow G (1994) Multiple adenovirus serotypes use alpha v integrins for infection. J Virol 68: 6811-6814
33. Mehta RJ, Diefenbach B, Brown A, Cullen E, Jonczyk A, Gussow D, Luckenbach GA, Goodman SL (1998) Transmembrane-truncated alphavbeta3 integrin retains high affinity for ligand binding: evidence for an 'inside-out' suppressor? Biochem J 330: 861-869
34. Menezes J, Leibold W, Klein G, Clements G (1975) Establishment and characterization of an Epstein-Barr virus (EBC)-negative lymphoblastoid B cell line (BJA-B) from an exceptional, EBV-genome-negative African Burkitt's lymphoma. Biomedicine 22: 276-284
35. Montross L, Watkins S, Moreland RB, Mamon H, Caspar DL, Garcea RL (1991) Nuclear assembly of polyomavirus capsids in insect cells expressing the major capsid protein VP1. J Virol 65: 4991-4998
36. Nakamura Y, Wada K, Wada Y, Doi H, Kanaya S, Gojobori T, Ikemura T (1996) Codon usage tabulated from the international DNA sequence databases. Nucleic Acids Res 24: 214-215
37. Pawlita M, Clad A, zur Hausen H (1985) Complete DNA sequence of lymphotropic papovavirus: prototype of a new species of the polyomavirus genus. Virology 143: 196-211
38. Pawlita M, Muller M, Oppenlander M, Zentgraf H, Herrmann M (1996) DNA encapsidation by viruslike particles assembled in insect cells from the major capsid protein VP1 of B-lymphotropic papovavirus. J Virol 70: 7517-7526
39. Rickwood D, Birnie GD (1975) Metrizamide, a new density-gradient medium. FEBS Lett 50: 102-110
40. Roivainen M, Hyypia T, Piirainen L, Kalkkinen N, Stanway G, Hovi T (1991) RGD-dependent entry of coxsackievirus A9 into host cells and its bypass after cleavage of VP1 protein by intestinal proteases. J Virol 65: 4735-4740
41. Roivainen M, Piirainen L, Hovi T, Virtanen I, Riikonen T, Heino J, Hyypia T(1994) Entry of coxsackievirus A9 into host cells: specific interactions with alpha v beta 3 integrin, the vitronectin receptor. Virology 203: 357-365
42. Sanchez R, Sali A (2000) Comparative protein structure modeling. Introduction and practical examples with modeller. Methods Mol Biol 143: 97-129
43. Sandalon Z, Oppenheim A (1997) Self-assembly and protein-protein interactions between the SV40 capsid proteins produced in insect cells. Virology 237: 414-421
44. Sharma A, Rao Z, Fry E, Booth T, Jones EY, Rowlands DJ, Simmons DL, Stuart DI (1997) Specific interactions between human integrin alpha v beta 3 and chimeric hepatitis B virus core particles bearing the receptor-binding epitope of foot-and-mouth disease virus. Virology 239: 150-157
45. Stanway G, Kalkkinen N, Roivainen M, Ghazi F, Khan M, Smyth M, Meurman O, Hyypia T (1994) Molecular and biological characteristics of echovirus 22, a representative of a new picornavirus group. J Virol 68: 8232-8238
46. Stehle T, Gamblin SJ, Yan Y, Harrison SC (1996) The structure of simian virus 40 refined at 3.1 A resolution. Structure 4: 165-182
47. Stehle T, Harrison SC (1996) Crystal structures of murine polyomavirus in complex with straight-chain and branched-chain sialyloligosaccharide receptor fragments. Structure 4: 183-194
48. Stehle T, Harrison SC (1997) High-resolution structure of a polyomavirus VP1-oligosaccharide complex: implications for assembly and receptor binding. EMBO J 16: 5139-5148
49. Stehle T, Yan Y, Benjamin TL, Harrison SC (1994) Structure of murine polyomavirus complexed with an oligosaccharide receptor fragment. Nature 369: 160-163
50. Stubenrauch K, Bachmann A, Rudolph R, Lilie H (2000) Purification of a viral coat protein by an engineered polyionic sequence. J Chromatogr B Biomed Sci Appl 737: 77-84
51. Valsesia-Wittmann S, Drynda A, Deleage G, Aumailley M, Heard JM, Danos O, Verdier G, Cosset FL (1994) Fiber knob modifications overcome low, heterogeneous expression of the coxsackievirus-adenovirus receptor that limits adenovirus gene transfer and oncolysis for human rhabdomyosarcoma cells. J Virol 68: 4609-4619
52. Verdaguer N, Mateu MG, Bravo J, Domingo E, Fita I (1996) Induced pocket to accommodate the cell attachment Arg-Gly-Asp motif in a neutralizing antibody against foot-and-mouth-disease virus. J Mol Biol 256: 364-376
53. Wickham TJ, Mathias P, Cheresh DA, Nemerow GR (1993) Integrins alpha v beta 3 and alpha v beta 5 promote adenovirus internalization but not virus attachment. Cell 73: 309-319
54. Xiong JP, Stehle T, Zhang R, Joachimiak A, Frech M, Goodman SL, Arnaout MA (2002) Crystal structure of the extracellular segment of integrin alpha Vbeta3 in complex with an Arg-Gly-Asp ligand. Science 296: 151-155
55. zur Hausen H, Gissmann L, Mincheva A, Boecker JF (1980) in Viruses in naturally occuring cancers. 365-373, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York