Elevated soluble cell adhesion molecules E-selectin and intercellular cell adhesion molecule-1 in type-2 diabetic patients with and without asymptomatic peripheral arterial disease

International Angiology

Volumn 23, Issue 2, 2004, Pages 128-133

  Elhadd, Tarik A ^a,b   Kennedy, G ^a   Robb, R ^a   McLaren, M ^a   Jung, R T ^a   Belch, J J F ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

^b KING FAISAL SPECIALIST HOSPITAL AND RESEARCH CENTER   (Saudi Arabia)

Author keywords

Cell adhesion molecules; Diabetes mellitus; E selectin; Endothelium vascular, physiology; Intercellular adhesion molecule 1

Indexed keywords

ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; HEMOGLOBIN A1C; INTERCELLULAR ADHESION MOLECULE 1;

ADULT; AGED; ARTICLE; ATHEROGENESIS; ATHEROSCLEROSIS; CARDIOVASCULAR DISEASE; CELL ACTIVATION; CEREBROVASCULAR DISEASE; CLINICAL ARTICLE; COHORT ANALYSIS; COMPARATIVE STUDY; CONTROLLED STUDY; CORRELATION ANALYSIS; CORRELATION COEFFICIENT; DISEASE COURSE; DISEASE DURATION; ENDOTHELIUM CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GLUCOSE BLOOD LEVEL; HUMAN; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; PERIPHERAL OCCLUSIVE ARTERY DISEASE; RANK SUM TEST; SYMPTOMATOLOGY; TEACHING HOSPITAL; UNITED KINGDOM;

ADULT; AGED; AGED, 80 AND OVER; ARTERIOSCLEROSIS; DIABETES MELLITUS, TYPE 2; DIABETIC ANGIOPATHIES; E-SELECTIN; FEMALE; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; MALE; MIDDLE AGED; PERIPHERAL VASCULAR DISEASES;

EID: 7044247959     PISSN: 03929590     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (34)

1. Fuller JH, Shipley MJ, Rose G, Jarrett RJ, Keen H. Mortality from coronary heart disease and stroke in relation to degree hyperglycaemia: The Whitehall Study Br Med J 1983;287:867-70.
2. Pirart J. Diabetes mellitus and its degenerative complications: A prospective study of 4,400 patients observed between 1947 and 1973. Diabetes Care 1978;1:168-88, 252-63.
3. Janka HU, Standle E, Mehnert H. Peripheral vascular disease in diabetes and its relation to cardiovascular risk factors: screening with the Doppler ultrasonic technique. Diabetes Care 1980;3:207-13.
4. Jensen T, Feldt-Rasmussen B, Bjerre-Knutsden J, Deckert T. Features of endothelial dysfunction in early diabetic nephropathy. Lancet 1989;1:461-3.
5. Gough SCL, Grant PJ. The fibrinolytic system in diabetes mellitus. Diabet Med 1991;8:898-905.
6. Jennings PE, McLaren M, Scott NA, Saniabadi AR, Belch JJF. The relationship of oxidative stress to the thrombotic tendency in type-1 diabetic patients with diabetic retinopathy. Diabet Med 1991;8:860-5.
7. Brownlee M, Vlassara H, Cerami A. Advanced glycosylation endproducts in tissues and the biochemical basis of diabetic complications. N Engl J Med 1988;318:1315-21.
8. Ross R. The pathogenesis of atherosclerosis: a prespective for the 1990s. Nature 1993;362:801-9.
9. Quinn MT, Parthasarathy S, Fong LG, Steinberg D. Oxidatively modified low density lipoproteins: A potential role in recruitment and retention of monocyte/macrophage during atherogenesis. Proc Natl Acad Sci U S A 1987;84:2995-8.
10. Lorenzi M. Glucose toxicity in the vascular complications of diabetes: the cellular prespective. Diabetes Metab Rev 1992;8:85-103.
11. Carter AM, Grant PJ. Vascular haemostasis, adhesion molecules and macrovascular disease in non-insulin dependent diabetes mellitus. Diabet Med 1997;14:423-32.
12. Blann AD, Lip GYH. Endothelial integrity, soluble adhesion molecules and platelets markers in Type-1 diabetes mellitus. Diabet Med 1998;15:634-44.
13. Elhadd TA, Jung RT, Stonebridge P, Newton RW, Belch JJF. Incidence of asymptomatic peripheral arterial disease in patients with diabetes mellitus, attending a hospital clinic. Adv Exp Med Biol 1997;428:45-8.
14. Maple C, Kirk G, McLaren M, Veale D, Belch JJF. Circadian variation exists for soluble ICAM-1 & E-selectin in healthy volunteers. Clin Sci 1998;94:537-40.
15. Smith CW. Potential significance of circulating E-selectin. Circulation 1997;95:1986-8.
16. Smith CW, Marlin SD, Rohlein R, Toman C, Anderson DC. Cooperative interaction of LFA and Mac-1 with intercellular adhesion molecule-1 in facilitating adherence and transendothelial migration of neutrophils in vitro. J Clin Invest 1989;83:2008-17.
17. Baumgartner-Prazer SM, Wagner L, Pettermann M, Gesse A, Waldhaus W. Modulation by high glucose of adhesion molecule expression in cultured endothelial cells. Diabetologia 1995;38:1367-70.
18. Vlassara H, Fuh H, Donnelly T, Cybulsky M. Advanced glycation endproducts promote adhesion molecules VCAM-1, ICAM-1 expression and atheroma formation in normal rabbits. Mol Med 1995;1:447-56.
19. Elhadd TA, Kennedy G, McLaren M, Newton RW, Greene SA, Belch JJF. Abnormal markers of endothelial cell activation and oxidative stress in children, adolescents and young adults with IDDM. Diabetes Metab Res Rev 1999;15:405-11.
20. Elhadd TA, Kennedy G, McLaren M, Stonebridge P, Belch JJF. Elevated levels of soluble E-selectin in diabetic patients with severe symptomatic peripheral arterial occlusive disease. Int Angiol 2000;19:171-5.
21. Witztum JL, Mahoney EM, Branks MJ, Fisher M, Elam R, Stenberg D. Non-enzymatic glycosylation of low-density lipoproteins alters its biological activity. Diabetes 1982;3:283-91.
22. Hickes M, Delbridge L, Yue DK, Reave TS. Catalysis of lipid peroxidation by glucose and glycosylated collagen. Bioch Biophys Res Comm 1988;151:649-55.
23. Goldstein JL, Ho YK, Basu SK, Brown MS. Binding sites on macrophages that mediates uptake and degradation of acetylated low density lipoproteins, producing massive cholesterol deposition. Proc Natl Acad Sci U S A. 1979;76:333-7.
24. Elhadd TA, Bancroft A, McLaren M, Newton RW, Belch JJF. Granulocyte aggregation in vitro in diabetes mellitus. Q J Med 1997;90:461-4.
25. Belch JJF, Shaw JW, Kirk G, Mclaren M, Robb R, Maple C et al.. The white blood cell adhesion molecule E-selectin predicts restenosis in patients with intermittent claudication undergoing percutaneous transluminal angioplasty. Circulation 1997;95:2027-31.
26. Olsen J, Whitelaw CM, McHardy KC, Pearson DW, Forrester JV. Soluble leucocyte adhesion molecules in diabetic retinopathy stimulate retinal capillary endothelial migration. Diabetologia 1997;40:1166-71.
27. Cominacini L, Fratta-Pacini A, Garbi U, Davoli A, De Santis A, Campgnola M et al. Elevated leves of soluble E-selectin in patients with IDDM and NIDDM: relation to metabolic control. Diabetologia 1995;38:1122-4.
28. Albertini JP, Valensi P, Lormeau B, Aurousseau MH, Ferriere F, Attali JR. Elevated concentration of soluble E-selectin and vascular cell adhesion molecule-1 in NIDDM: effect of intensified insulin treatment. Diabetes Care 1998;21:1008-13.
29. De Mattia G, Bravi MC, Laurenti O, Cassone-Faldetta Mm Proietti A, De Luca O et al. Reduction of oxidative stress by oral N-acetyl-L-cysteine treatment decreases plasma soluble vascular cell adhesion molecule-1 concentration in non-obese, non-dyslipidaemic normotensive patients with non-insulin dependent diabetes mellitus. Diabetologia 1998;41:1392-6.
30. Jennings PE, Scott NA, Saniabadi AR, Belch JJF. Effects of gliclizide on platelet reactivity and free radicals in Type-2 diabetic patients: clinical assessment. Metabolism 1992;41 Suppl 1:36-9.
31. Desfaits A-C, Serri O, Renier G. Normalisation of plasma lipid peroxides, monocyte adhesion and tumour necrosis factor-α production in NIDDM patients after gliclazide treatment. Diabetes Care 1998;21:487-93.
32. Elhadd TA, Jennings PE, Newton RW, Belch JJF. Anti-oxidant effects of gliclazide & soluble adhesion molecules in Type-2 (non-insulin dependent) diabetes mellitus. Diabetes Care 1999;22:528-30.
33. Mancini GBJ, Henry GC, Macaya C, O'Neill BJ, Pucillo AL, Carere RG et al. Angiotensin-converting enzyme inhibition with quinalapril improves endothelial vasomotor dysfunction in patients with coronary artery disease. The TREND Study. Circulation 1996;94:259-64.
34. Wu MS, Johnston P, Shen WH, Hollenbeck CB, Jeng CY, Goldfene ID et al. Effect of metformin on carbohydrate and lipoprotein metabolism in NDDM patients. Diabetes Care 1990;13:1-8.