Peripheral effects of serotonin on the contractile responses of rat seminal vesicles and vasa deferentia

Journal of Andrology

Volumn 25, Issue 6, 2004, Pages 893-899

  Kim, Soo Woong ^a   Paick, Jae Seung ^a  

^a Seoul National University College of Medicine   (South Korea)

Author keywords

5 hydroxytryptamine; Ejaculation; Seminal tract

Indexed keywords

CLOMIPRAMINE; FLUOXETINE; MESSENGER RNA; SEROTONIN; SEROTONIN 1A RECEPTOR; SEROTONIN 1B RECEPTOR; SEROTONIN 2C RECEPTOR; SEROTONIN AGONIST;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; EJACULATION; GENE EXPRESSION; HYPOGASTRIC NERVE; IN VITRO STUDY; IN VIVO STUDY; MALE; MUSCLE CONTRACTION; NERVE STIMULATION; NEUROTRANSMISSION; NONHUMAN; PRESSURE MEASUREMENT; PRIORITY JOURNAL; RAT; REGULATORY MECHANISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEMINAL VESICLE; SEROTONINERGIC SYSTEM; VAS DEFERENS;

EID: 7044241357     PISSN: 01963635     EISSN: None     Source Type: Journal    
DOI: 10.1002/j.1939-4640.2004.tb03159.x     Document Type: Article

References (19)

1. Ahlenius S, Larsson K. Evidence for an involvement of 5-HT1B receptors in the inhibition of male rat ejaculatory behavior produced by 5-HTP. Psychopharmacology (Berl). 1998;137:374-382.
2. Ahlenius S, Larsson K. Synergistic actions of the 5-HT1A receptor antagonist WAY-100635 and citalopram on male rat ejaculatory behavior. Eur J Pharmacol. 1999;379:1-6.
3. Ahlenius S, Larsson K, Svensson L. Further evidence for an inhibitory role of central 5-HT in male rat sexual behavior. Psychopharmacology (Berl). 1980;68:217-220.
4. Berendsen HHG, Broekkamp CLE. Comparison of stimulus properties of fluoxetine and 5-HT receptor agonists in a conditioned taste aversion procedure. Eur J Pharmacol. 1994;253:83-89.
5. Erspamer V. 5-Hydroxytryptamine and related indolealkylamines. In: Erspamer V, ed. Handbook of Experimental Pharmacology. New York: Springer-Verlag; 1966:132-181.
6. Farthing MJG. 5-Hydroxytryptamine and 5-hydroxytryptamine-3 receptor antagonists. Scand J Gastroenterol. 1991;26:92-100.
7. Gonzales G, Mendoza L, Ruiz J, Torrejon J. A demonstration that 5-hydroxytryptamine administered peripherally can affect sexual behavior in male rats. Life Sci. 1982;31:2775-2781.
8. Grahame-Smith DG. Serotonin (5-hydroxytryptamine, 5-HT). Q J Med. 1988;67:459-466.
9. Hillegaart V, Ahlenius S. Facilitation and inhibition of male rat ejaculatory behaviour by the respective 5-HT1A and 5-HT1B receptor agonist 8-OH-DPAT and anpirtoline, as evidenced by use of the corresponding new and selective receptor antagonists NAD-299 and NAS-181. Br J Pharmacol. 1998;125:1733-1743.
10. Hsieh JT, Chang HC, Law HS, Hsieh CH, Cheng JT. In vivo evaluation of serotonergic agents and alpha-adrenergic blockers on premature ejaculation by inhibiting the seminal vesicle pressure response to electrical nerve stimulation. Br J Urol. 1998;82:237-240.
11. Kihara K, de Groat W. Sympathetic efferent pathways projecting bilaterally to the vas deferens in the rat. Anat Res. 1997;248:291-299.
12. Kim SC, Seo KK. Efficacy and safety of fluoxetine, sertraline and clomipramine in patients with premature ejaculation: a double-blind, placebo controlled study. J Urol. 1998;159:425-427.
13. Kim SC, Seo KK, Han JH, Lee MY. Inhibitory effect of serotonergic drugs on contractile response of the rat vas deferens to electrical nerve stimulation: in vivo study. J Urol. 2000;163:1988-1991.
14. Kim SW, Paick JS. Short-term analysis of the effects of as needed use of sertraline at 5 PM for the treatment of premature ejaculation. Urology. 1999;54:544-547.
15. Learmonth JR. A contribution to the neurophysiology of the urinary bladder in man. Brain. 1931;54:147-176.
16. Mclntosh TK, Barfied RJ. Brain monoaminergic control of male reproduction behavior. I. Serotonin and the post-ejaculatory refractory period. Behav Brain Res. 1984;12:255-265.
17. Palvimaki EP, Roth BL, Majasuo H, Laakso A, Kuoppamaki M, Syvalahti E, Hietala J. Interactions of selective Serotonin reuptake inhibitors with the serotonin 5-HT2c receptor. Psychopharmacology (Berl). 1996;126:234-240.
18. Waldinger MD, Berendsen HH, Blok BF, Olivier B, Holstege G. Premature ejaculation and serotonergic antidepressants-induced delayed ejaculation: the involvement of the serotoninergic system. Behav Br Res. 1998a;92:111-118.
19. Waldinger MD, Hengeveld MW, Zwinderman AH, Olivier B. Effect of SSRI antidepressants on ejaculation: a double-blind, randomized, placebo-controlled study with fluoxetine, fluvoxamine, paroxetine, and sertraline. J Clin Psychopharmacol. 1998b;18:274-281.