Drug-induced increased mitochondrial biogenesis in a liver biopsy

Experimental and Molecular Pathology

Volumn 77, Issue 3, 2004, Pages 201-204

  Kamal, Mohammad A ^a,c   French, Samuel W ^b  

^a VA LONG BEACH HEALTHCARE SYSTEM   (United States)

^b HARBOR UCLA MEDICAL CENTER   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Biogenesis; Liver biopsy; Mitochondria

Indexed keywords

COTRIMOXAZOLE; LACTIC ACID; MITOCHONDRIAL PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE; PYRUVIC ACID; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; STAVUDINE;

ADULT; ARTICLE; BIOGENESIS; CASE REPORT; CITRIC ACID CYCLE; DRUG EFFECT; ELECTRON MICROSCOPY; ELECTRON TRANSPORT; FATTY ACID OXIDATION; FEMALE; HEPATITIS C; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HUMAN TISSUE; INTRAHEPATIC CHOLESTASIS; LACTIC ACIDOSIS; LIVER BIOPSY; LIVER MITOCHONDRION; LIVER TOXICITY; MITOCHONDRIAL DNA REPLICATION; MITOCHONDRIAL MEMBRANE; OXIDATIVE PHOSPHORYLATION; PROTEIN DEPLETION;

ADULT; ANTI-HIV AGENTS; ANTIRETROVIRAL THERAPY, HIGHLY ACTIVE; BIOPSY; CHOLESTASIS; DNA REPLICATION; DNA, MITOCHONDRIAL; FEMALE; HEPATOCYTES; HUMANS; MICROSCOPY, ELECTRON, TRANSMISSION; MITOCHONDRIA, LIVER; MITOCHONDRIAL PROTEINS; STAVUDINE; TRIMETHOPRIM-SULFAMETHOXAZOLE COMBINATION;

EID: 7044239103     PISSN: 00144800     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yexmp.2004.06.004     Document Type: Article

References (8)

1. Alberts, B., et al. Molecular Biology of the Cell. Second Edition. Garland Publishing, Inc. Chapter 7. The Genomes of Mitochondria and Chloroplasts.387.
2. K. Brinkman Hyperlactemia and hepatic steatosis as feature of mitochondrial toxicity of nucleoside analogue reverse trancriptase inhibitors Clin. Infect. Dis. 31 2000 167 169
3. S. Krähenbühl Mitochondria: important target for drug toxicity J. Hepatol. 34 34 2001 334 336
4. H. Mandel The hepatic mitochondrial DNA depletion syndrome: ultrastructural changes in liver biopsies Hepatology 34 4 2001 776 784
5. G. Moyle Toxicity of antiretroviral nucleoside and nucleotide analogues. Is mitochondrial toxicity the only mechanism? Drug Saf. 23 6 2000 467 481
6. B. Tandler Ultrastructure of oncocytoma of the parotid gland Lab. Invest. 23 4 1970 567 580
7. B. Tandler, and F.H. Shipkey Ultrastructure of Warthin's Tumor. I. Mitochondria J. Ultrastruct. Res. 11 1964 292
8. H. Wu Regulation of mitochondrial biogenesis in skeletal muscle by CaMK Science 296 2002 349 352