Taurolidine is effective in the treatment of central venous catheter-related bloodstream infections in cancer patients

International Journal of Antimicrobial Agents

Volumn 24, Issue 5, 2004, Pages 491-495

  Koldehoff, M ^a   Zakrzewski , J L ^b  

^a UNIVERSITY HOSPITAL ESSEN   (Germany)

^b CITY UNIVERSITY OF NEW YORK   (United States)

Author keywords

Antimicrobial lock solution; Bloodstream infections; Taurolidine; Totally implantable intravascular devices; Treatment

Indexed keywords

ANTIINFECTIVE AGENT; CEFAZOLIN; CEFTAZIDIME; CEFTRIAXONE; CIPROFLOXACIN; GENTAMICIN; IMIPENEM; METRONIDAZOLE; PIPERACILLIN; SULTAMICILLIN; TAUROLIDINE; TAZOBACTAM; VANCOMYCIN;

ACINETOBACTER BAUMANNII; ADULT; AGED; ANTIBIOTIC THERAPY; ARTICLE; BLOOD TOXICITY; CANCER PATIENT; CATHETER RELATED BLOODSTREAM INFECTION; CLINICAL ARTICLE; CLINICAL TRIAL; DRUG EFFICACY; ESCHERICHIA COLI; HUMAN; HYPERTENSION; INFECTION; INTRAVENOUS CATHETER; OPEN STUDY; PRIORITY JOURNAL; PSEUDOMONAS; PSEUDOMONAS AERUGINOSA; RECURRENT INFECTION; STAPHYLOCOCCUS; STAPHYLOCOCCUS AUREUS; STENOTROPHOMONAS MALTOPHILIA; TREATMENT OUTCOME;

ADULT; ANTI-INFECTIVE AGENTS; BACTEREMIA; CATHETERIZATION, CENTRAL VENOUS; FEMALE; HUMANS; MALE; NEOPLASMS; PILOT PROJECTS; PROSTHESIS-RELATED INFECTIONS; SOLUTIONS; TAURINE; THIADIAZINES; TREATMENT OUTCOME;

EID: 7044235802     PISSN: 09248579     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijantimicag.2004.06.006     Document Type: Article

References (32)

1. J.S. Groeger, A.B. Lucas, and H.T. Thaler Infectious morbidity associated with long-term use of venous access devices in patients with cancer Ann. Intern. Med. 119 1993 1168 1174
2. C.H. Barrios, J.E. Zuke, B. Blaes, J.D. Hirsch, and A.P. Lyss Evaluation of an implantable venous access system in a general oncology population Oncology 49 1992 474 478
3. R. Fuchs, L. Leimer, G. Koch, and M. Westerhausen Klinische Erfahrungen mit bakteriell kontaminierten Port-a-Cath Systemen bei Tumorpatienten Dtsch. Med. Wochenschr. 112 1987 1615 1618
4. J.R. Gowardman, C. Montgomery, and S. Thirlwell Central venous catheter-related bloodstream infections: an analysis of incidence and risk factors in a cohort of 400 patients Intensive Care Med. 24 1998 1034 1039
5. J.F. Timsit, J.C.H. Farkas, and J.M. Boyer Central vein catheter-related thrombosis in intensive care patients: incidence, risk factors, and relationship with catheter-related sepsis Chest 114 1998 207 213
6. F.D. Daschner The transmission of infection in hospitals by staff carriers, methods of prevention and control Infect. Control 6 1985 97 98
7. R.O. Darouiche, I.I. Raad, S.O. Heard Catheter Study Group A comparison of two antimicrobial-impregnated central venous catheters N. Engl. J. Med. 340 1999 1 8
8. F. Erb, M. Imbenotte, and J. Huveene Structural investigation of a new organic antimicrobial: taurolidine analytical study and application to identification and quantitation in biological fluids. Eur. J. Drug Metab. Pharmacokinet. 8 1983 163 173
9. ®, a novel antimicrobial agent J. Appl. Bacteriol. 62 1987 315 320
10. J.R. Monson, P.S. Ramsey, and J.H. Donohue Taurolidine inhibits tumour necrosis factor (TNF) toxicity - new evidence of TNF and endotoxin synergy Eur. J. Surg. Oncol. 19 1993 226 231
11. M.L. Leithauser, P.M. Rob, and K. Sack Pentoxifylline, cyclosporine A and taurolidine inhibit endotoxin-stimulated tumour necrosis factor-alpha production in rat mesangial cell cultures Exp. Nephrol. 5 1997 100 104
12. P. Calabresi, F.A. Goulette, and J.W. Darnowski Taurolidine: cytotoxic and mechanistic evaluation of a novel antineoplastic agent Cancer Res. 61 2001 6816 6821
13. ® W.L. Bruckner R.W.P. Pfirrman Proceedings of the International Taurolin Symposium Switzerland: Urban and Schwarzenberg 1985
14. M.K. Browne, G.B. Leslie, and R.W. Pfirrmann Taurolin, a new chemotherapeutic agent J. Appl. Bacteriol. 41 1976 363 368
15. C.B. Shah, M.W. Mittelman, and J.W. Costerton Antimicrobial activity of a novel catheter lock solution Antimicrob. Agents Chemother. 46 2002 1674 1679
16. J.I. Blenkharn In vitro antibacterial activity of noxythiolin and taurolidine J. Pharm. Pharmacol. 42 1990 589 590
17. A.C. McCartney, and M.K. Browne Clinical studies on administration of taurolin in severe sepsis: a preliminary study Prog. Clin. Biol. Res. 272 1988 361 371
18. M.K. Browne, G.B. Leslie, R.W. Pfirrmann, and H. Brodhage The in vitro and in vivo activity of Taurolin against anaerobic pathogenic organisms Surg. Gynecol. Obstet. 145 1977 842 846
19. W.H. Traub, B. Leonhard, and D. Bauer Taurolidine: in vitro activity against multiple-antibiotic-resistant, nosocomially significant clinical isolates of Staphylococcus aureus, Enterococcus faecium, and diverse Enterobacteriaceae Chemotherapy 39 1993 322 330
20. D.A. Reeves, and F.A.W. Schwertzer Experimental studies with an antimicrobial substance, Taurolin Proceedings of the 8th International Congress of Chemotherapy Athens: Helenic Society for Chemotherapy 1974
21. K. Sodemann, H.D. Polaschegg, and B. Feldmer Two years' experience with Dialock and CLS (a new antimicrobial lock solution) Blood Purif. 19 2001 251 254
22. F. Quarello, and G. Forneris Prevention of haemodialysis catheter-related bloodstream infection using an antimicrobial lock Blood Purif 20 2002 87 92
23. B. Jurewitsch, T. Lee, J. Park, and K. Jeejeebhoy Taurolidine 2% as an antimicrobial lock solution for prevention of recurrent catheter-related bloodstream infections J. Parenter. Enteral. Nutr. 22 1998 242 244
24. I. Raad, R. Darouich, J. Dupuis The Texas Medical Center Catheter Study Group Central venous catheters coated with minocycline and rifampicin for the prevention of catheter-related colonisation and bloodstream infections: a randomised, double-blind trial Ann. Intern. Med. 127 1997 267 274
25. D.G. Maki, S.M. Stolz, S. Wheeler, and L.A. Mermel Prevention of central venous catheter-related bloodstream infection by use of an antiseptic- impregnated catheter: a randomised, controlled trial Ann. Intern. Med. 127 1997 257 266
26. I. Raad Vascular catheters impregnated with antimicrobial agents: present knowledge and future direction Infect. Control. Hosp. Epidemiol. 18 1997 227 229
27. P. Longuet, M. Douard, and C. Maslo Limited efficacy of antibiotic-lock technique (ALT) in catheter-related bacteremia of totally implanted port (TIP) in HIV infected and oncologic patients Proceedings of the Program and Abstracts of the 35th Interscience Conference on Antimicrobial Agents and Chemotherapy of the American Society for Microbiology Washington, DC: American Society for Microbiology 1995
28. ® in peritonitis Br. J. Clin. Pharmacol. 12 1981 695 699
29. ® in established bacterial peritonitis Surg. Gynecol. Obstet. 146 1978 721 724
30. Sodemann K, Feldmer B, Polaschegg H, et al. A new anti-infective lock solution applied together with a subcutaneous port system. Angioaccess for Haemodialysis, Abstract 208; 1999.
31. ® - a possible additive for parenteral nutrition solutions Clin. Nutr. 6 1987 35 38
32. B. Messing, S. Peitra-Cohen, A. Debure, M. Beliah, and J.J. Bernier Antibiotic-lock technique: a new approach to optimal therapy for catheter-related sepsis in home-parenteral nutrition patients J. Parenter Enteral. Nutr. 12 1988 185 189