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7044244490
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note
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3)
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14
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0030607141
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15
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7044258561
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note
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Borohydride, polymer supported (on Amberlite® IRA-400), supplier: Aldrich Chemical Company, Inc
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16
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7044255759
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note
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4-Benzyloxybenzaldehyde polystyrene HL (200-400 mesh), 2% DVB, supplier Novabiochem
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17
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7044278662
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note
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Methylisothiocyanate polystyrene HL (200-400 mesh), 2% DVB, supplier Novabiochem
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18
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7044282226
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note
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Compounds 7a-n: 50 μmol of aldehyde 5 was added to a mixture of amine 6 (60 μmol, 1.2 equiv) and triethylamine (66 μmol, 1.3 equiv), in anhydrous methanol (1 mL) and the resulting mixture was stirred at room temperature for 18 h. Borohydride (100 μmol, 2 equiv) supported on resin were then added and stirring was maintained for 2 additional hours. Compounds 7a-l: 60 μmol (1.2 equiv) of 4-benzyloxybenzaldehyde polystyrene resin was added and the mixture stirred for 18 h at room temperature. Compounds 7m and 7n: 60 μmol (1.2 equiv) of methylisothiocyanate polystyrene resin was added and the mixture stirred for 18 h at room temperature. In both cases, the resins were filtered and washed with MeOH. The solvent was evaporated and compounds 7a-n were obtained as yellow oils
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19
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7044279330
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note
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Mass spectra were acquired on a single quadrupole electrospray mass spectrometer (Micromass, Platform model) and HPLC retention times were acquired on an HPLC system (HP 1100) equipped with a photodiode array UV detector
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20
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2342455204
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M.-C. Brezak, M. Quaranta, O. Mondésert, M.-O. Galcera, O. Lavergne, F. Alby, M. Cazales, V. Baldin, C. Thurieau, J. Harnett, C. Lanco, P.G. Kasprzyk, G.P. Prevost, and B. Ducommun Cancer Res. 64 2004 3320 3325
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Brezak, M.-C.1
Quaranta, M.2
Mondésert, O.3
Galcera, M.-O.4
Lavergne, O.5
Alby, F.6
Cazales, M.7
Baldin, V.8
Thurieau, C.9
Harnett, J.10
Lanco, C.11
Kasprzyk, P.G.12
Prevost, G.P.13
Ducommun, B.14
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