Reduced hypothermic and hypnotic responses to ethanol in PACAP-deficient mice

Regulatory Peptides

Volumn 123, Issue 1-3 SPEC. ISS., 2004, Pages 95-98

  Tanaka, Kazuhiro ^a   Hashimoto, Hitoshi ^a   Shintani, Norihito ^a   Yamamoto, Akiko ^a   Baba, Akemichi ^a,b  

^a OSAKA UNIVERSITY   (Japan)

^b OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Alcoholism; Drosophila memory mutant amnesiac; Righting reflex; Sleep

Indexed keywords

ALCOHOL; HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE;

ALCOHOL BLOOD LEVEL; ALCOHOL METABOLISM; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; HYPNOSIS; HYPOTHERMIA; INTERMETHOD COMPARISON; LATENT PERIOD; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; PRIORITY JOURNAL; REDUCTION KINETICS; RIGHTING REFLEX; SENSITIVITY ANALYSIS; SLEEP TIME; STATISTICAL SIGNIFICANCE; WILD TYPE;

ANIMALS; DROSOPHILA; ETHANOL; HYPNOTICS AND SEDATIVES; HYPOTHERMIA; MALE; MICE; MICE, INBRED ICR; MICE, KNOCKOUT; NERVE GROWTH FACTORS; NEUROPEPTIDES; NEUROTRANSMITTER AGENTS; PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE; SLEEP;

MAMMALIA;

EID: 7044227724     PISSN: 01670115     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.regpep.2004.05.017     Document Type: Article

References (23)

1. Vaudry D., Gonzalez B.J., Basille M., Yon L., Fournier A., Vaudry H. Pituitary adenylate cyclase-activating polypeptide and its receptors: from structure to functions. Pharmacol. Rev. 52:2000;269-324
2. Hashimoto H., Shintani N., Baba A. Higher brain functions of PACAP and a homologous Drosophila memory gene amnesiac: insights from knockouts and mutants. Biochem. Biophys. Res. Commun. 297:2002;427-431
3. Feany M.B., Quinn W.G. A neuropeptide gene defined by the Drosophila memory mutant amnesiac. Science. 268:1995;869-873
4. Zhong Y. Mediation of PACAP-like neuropeptide transmission by coactivation of Ras/Raf and cAMP signal transduction pathways in Drosophila. Nature. 375:1995;588-592
5. Harmar A.J., Arimura A., Gozes I., Journot L., Laburthe M., Pisegna J.R., et al. International Union of Pharmacology: XVIII. Nomenclature of receptors for vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide. Pharmacol. Rev. 50:1998;265-270
6. Hashimoto H., Ishihara T., Shigemoto R., Mori K., Nagata S. Molecular cloning and tissue distribution of a receptor for pituitary adenylate cyclase-activating polypeptide. Neuron. 11:1993;333-342
7. Aino H., Hashimoto H., Ogawa N., Nishino A., Yamamoto K., Nogi H., et al. Structure of the gene encoding the mouse pituitary adenylate cyclase-activating polypeptide receptor. Gene. 164:1995;301-304
8. Hashimoto H., Nishino A., Shintani N., Hagihara N., Copeland N.G., Jenkins N.A., et al. Genomic organization and chromosomal location of the mouse vasoactive intestinal polypeptide 1 (VPAC1) receptor. Genomics. 58:1999;90-93
9. Yamamoto K., Hashimoto H., Hagihara N., Nishino A., Fujita T., Matsuda T., et al. Cloning and characterization of the mouse pituitary adenylate cyclase-activating polypeptide (PACAP) gene. Gene. 211:1998;63-69
10. Hashimoto H., Nogi H., Mori K., Ohishi H., Shigemoto R., Yamamoto K., et al. Distribution of the mRNA for a pituitary adenylate cyclase-activating polypeptide receptor in the rat brain: an in situ hybridization study. J. Comp. Neurol. 371:1996;567-577
11. Hashimoto H., Shintani N., Nishino A., Okabe M., Ikawa M., Matsuyama S., et al. Mice with markedly reduced PACAP (PAC1) receptor expression by targeted deletion of the signal peptide. J. Neurochem. 75:2000;1810-1817
12. Hashimoto H., Shintani N., Tanaka K., Mori W., Hirose M., Matsuda T., et al. Altered psychomotor behaviors in mice lacking pituitary adenylate cyclase-activating polypeptide (PACAP). Proc. Natl. Acad. Sci. U. S. A. 98:2001;13355-13360
13. Matsuyama S., Matsumoto A., Hashimoto H., Shintani N., Baba A. Impaired long-term potentiation in vivo in the dentate gyrus of pituitary adenylate cyclase-activating polypeptide (PACAP) or PACAP type 1 receptor-mutant mice. NeuroReport. 14:2003;2095-2098
14. Otto C., Kovalchuk Y., Wolfer D.P., Gass P., Martin M., Zuschratter W., et al. Impairment of mossy fiber long-term potentiation and associative learning in pituitary adenylate cyclase activating polypeptide type I receptor-deficient mice. J. Neurosci. 21:2001;5520-5527
15. Otto C., Martin M., Wolfer D.P., Lipp H.P., Maldonado R., Schutz G. Altered emotional behavior in PACAP-type-I-receptor-deficient mice. Brain Res. Mol. Brain Res. 92:2001;78-84
16. Marley R.J., Miner L.L., Wehner J.M., Collins A.C. Differential effects of central nervous system depressants in long-sleep and short-sleep mice. J. Pharmacol. Exp. Ther. 238:1986;1028-1033
17. Harris R.A., McQuilkin S.J., Paylor R., Abeliovich A., Tonegawa S., Wehner J.M. Mutant mice lacking the gamma isoform of protein kinase C show decreased behavioral actions of ethanol and altered function of γ-aminobutyrate type A receptors. Proc. Natl. Acad. Sci. U. S. A. 92:1995;3658-3662
18. 2+ elevation but not cyclic AMP in PACAP-induced p38 MAP kinase activation in PC12 cells. Regul. Pept. 109:2002;149-153
19. Thiele T.E., Willis B., Stadler J., Reynolds J.G., Bernstein I.L., McKnight G.S. High ethanol consumption and low sensitivity to ethanol-induced sedation in protein kinase A-mutant mice. J. Neurosci. 20:2000;RC75
20. Bellen H.J. The fruit fly: a model organism to study the genetics of alcohol abuse and addiction? Cell. 93:1998;909-912
21. Schuckit M.A. Low level of response to alcohol as a predictor of future alcoholism. Am. J. Psychiatry. 151:1994;184-189
22. Spanagel R., Siegmund S., Cowen M., Schroff K.C., Schumann G., Fiserova M., et al. The neuronal nitric oxide synthase gene is critically involved in neurobehavioral effects of alcohol. J. Neurosci. 22:2002;8676-8683
23. Thiele T.E., Marsh D.J., Ste-Marie L., Bernstein I.L., Palmiter R.D. Ethanol consumption and resistance are inversely related to neuropeptide Y levels. Nature. 396:1998;366-369