Hydrophilic and lipophilic moisturizers have similar penetration profiles but different effects on SC water distribution in vivo

Experimental Dermatology

Volumn 18, Issue 11, 2009, Pages 954-961

  Caussin, Julia ^a   Rozema, Evelien ^a   Gooris, Gert S ^a   Wiechers, Johann W ^b   Pavel, Stan ^c   Bouwstra, Joke A ^a  

^a LEIDEN UNIVERSITY   (Netherlands)

^b Uniqema   (Netherlands)

^c LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Attenuated total reflectance Fourier transform infrared; Moisturization; Natural moisturizing factor; Stratum corneum; Tape stripping

Indexed keywords

DERMATOLOGICAL AGENT; GLUCOSE; GLYCEROL; GLYCEROL MONOISOSTEARATE; GLYCEROL STEARATE; ISOPROPYLISOSTEARATE; ISOSTEARYLISOSTEARATE; UNCLASSIFIED DRUG; WATER;

ADULT; ARTICLE; CONTROLLED STUDY; DRUG PENETRATION; FEMALE; HUMAN; HUMAN EXPERIMENT; HYDRATION; HYDROPHILICITY; IN VIVO STUDY; INFRARED SPECTROSCOPY; LIPOPHILICITY; MALE; NORMAL HUMAN; SKIN PENETRATION; STRATUM CORNEUM; TEST STRIP; WATER RETENTION;

ADMINISTRATION, CUTANEOUS; ADULT; BODY WATER; DRUG DESIGN; EMOLLIENTS; FEMALE; HUMANS; MALE; PERMEABILITY; SKIN; SKIN ABSORPTION; SOLUBILITY; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; TIME FACTORS; WATER;

EID: 70350786869     PISSN: 09066705     EISSN: 16000625     Source Type: Journal    
DOI: 10.1111/j.1600-0625.2009.00881.x     Document Type: Article

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