메뉴 건너뛰기




Volumn 75, Issue 10, 2009, Pages 1152-1156

Cytotoxic phenanthroindolizidine alkaloids from the roots of ficus septica

Author keywords

Cytotoxicity; Ficus septica; Ficuseptine; Moraceae; Phenanthroindolizidines

Indexed keywords

ALKALOID DERIVATIVE; ANTOFINE; DEHYDROTYLOPHORINE; FICUS SEPTICA EXTRACT; FICUSEPTINE A; FICUSEPTINE B; FICUSEPTINE E; FICUSEPTINE F; FICUSEPTINE G; FICUSEPTINE H; FICUSEPTINE I; FICUSEPTINE J; FICUSEPTINE K; FICUSEPTINE L; FICUSEPTINE M; FICUSEPTINE N; ISOTYLOCREBRINE; ISOTYLOCREBRINE N OXIDE; PHENANTHROINDOLIZIDINE DERIVATIVE; PLANT EXTRACT; TYLOCREBRINE; TYLOCREBRINE N OXIDE; TYLOPHORINE; TYLOPHORINE N OXIDE; UNCLASSIFIED DRUG; ALKALOID; ANTINEOPLASTIC AGENT;

EID: 70350784073     PISSN: 00320943     EISSN: 14390221     Source Type: Journal    
DOI: 10.1055/s-0029-1185483     Document Type: Article
Times cited : (32)

References (28)
  • 1
    • 0000766485 scopus 로고
    • The chemical examination of Tylophora asthmatica and isolation of the alkaloids tylophorine and tylophorinine
    • Ratnagiriswaran AN, Venkatachalam K. The chemical examination of Tylophora asthmatica and isolation of the alkaloids tylophorine and tylophorinine. Indian J Med Res 1935; 22: 433-441
    • (1935) Indian J Med Res , vol.22 , pp. 433-441
    • Ratnagiriswaran, A.N.1    Venkatachalam, K.2
  • 2
    • 0035210509 scopus 로고    scopus 로고
    • Isolation, total synthesis and biological activity of phenanthroindolizidine and phenanthroquinolizidine alkaloids
    • Li Z, Jin Z, Huang R. Isolation, total synthesis and biological activity of phenanthroindolizidine and phenanthroquinolizidine alkaloids. Synthesis 2001: 2365-2378
    • (2001) Synthesis , pp. 2365-2378
    • Li, Z.1    Jin, Z.2    Huang, R.3
  • 3
    • 33845762339 scopus 로고    scopus 로고
    • Synthesis and structure- activity studies of antofine analogues as potential anticancer agents
    • Fu Y, Lee SK, Min HY, Lee T, Lee J, Cheng M, Kima S. Synthesis and structure- activity studies of antofine analogues as potential anticancer agents. Bioorg Med Chem Lett 2007; 17: 97-100
    • (2007) Bioorg Med Chem Lett , vol.17 , pp. 97-100
    • Fu, Y.1    Lee, S.K.2    Min, H.Y.3    Lee, T.4    Lee, J.5    Cheng, M.6    Kima, S.7
  • 4
    • 0010584413 scopus 로고
    • Anticancer agents based on natural product models
    • Cassady JM, Douros JD, editors. London: Academic Press
    • Suffness M, Douros J. Anticancer agents based on natural product models. In: Cassady JM, Douros JD, editors. Medicinal chemistry, Vol.16. London: Academic Press; 1980: 465-487
    • (1980) Medicinal Chemistry , vol.16 , pp. 465-487
    • Suffness, M.1    Douros, J.2
  • 5
    • 0001375348 scopus 로고
    • (-)-Antofine: A phenanthroindolizidine from Vincetoxicum nigrum
    • Capo M, Saa JM. (-)-Antofine: a phenanthroindolizidine from Vincetoxicum nigrum. J Nat Prod 1989; 52: 389-390
    • (1989) J Nat Prod , vol.52 , pp. 389-390
    • Capo, M.1    Saa, J.M.2
  • 8
    • 0022886244 scopus 로고
    • Traditional medicinal plants of Morobe province, Papua New Guinea
    • Holdsworth D, Damas K. Traditional medicinal plants of Morobe province, Papua New Guinea. Int J Crude Drug Res 1986; 24: 217-225
    • (1986) Int J Crude Drug Res , vol.24 , pp. 217-225
    • Holdsworth, D.1    Damas, K.2
  • 9
    • 0028971416 scopus 로고
    • Comparison of [3H]thymidine incorporation with MTT- and MTS-based bioassays for human and murine IL-2 and IL-4 analysis. Tetrazolium assays provide markedly enhanced sensitivity
    • Gieni RS, Hayglass KT. Comparison of [3H]thymidine incorporation with MTT- and MTS-based bioassays for human and murine IL-2 and IL-4 analysis. Tetrazolium assays provide markedly enhanced sensitivity. J Immunol Methods 1995; 187: 85-93
    • (1995) J Immunol Methods , vol.187 , pp. 85-93
    • Gieni, R.S.1    Hayglass, K.T.2
  • 10
    • 0031593138 scopus 로고    scopus 로고
    • The sensitivity and specificity of the MTS tetrazolium assay for detecting the in vitro cytotoxicity of 20 chemicals using human cell lines
    • Malich G, Markovic B, Winder C. The sensitivity and specificity of the MTS tetrazolium assay for detecting the in vitro cytotoxicity of 20 chemicals using human cell lines. Toxicology 1997; 124: 179-192
    • (1997) Toxicology , vol.124 , pp. 179-192
    • Malich, G.1    Markovic, B.2    Winder, C.3
  • 11
    • 7444239691 scopus 로고    scopus 로고
    • Antitumor agents 239. Isolation, structure elucidation, total synthesis, and anti-breast cancer activity of neo-tanshinlactone from Salvia miltiorrhiza
    • Wang X, Bastow KF, Sun CM, Lin YL, Yu HJ, Don MJ, Wu TS, Nakamura S, Lee KH. Antitumor agents 239. Isolation, structure elucidation, total synthesis, and anti-breast cancer activity of neo-tanshinlactone from Salvia miltiorrhiza. J Med Chem 2004; 47: 5816-5819
    • (2004) J Med Chem , vol.47 , pp. 5816-5819
    • Wang, X.1    Bastow, K.F.2    Sun, C.M.3    Lin, Y.L.4    Yu, H.J.5    Don, M.J.6    Wu, T.S.7    Nakamura, S.8    Lee, K.H.9
  • 13
    • 0000318316 scopus 로고
    • Alkaloids of Ficus species Occurrence of indolizidine alkaloids in Ficus septica
    • Russel JH. Alkaloids of Ficus species. Occurrence of indolizidine alkaloids in Ficus septica. Naturwissenschaften 1963; 50: 443-444
    • (1963) Naturwissenschaften , vol.50 , pp. 443-444
    • Russel, J.H.1
  • 15
    • 0036899636 scopus 로고    scopus 로고
    • Phenanthroindolizidine alkaloids and their cytotoxicity from the leaves of Ficus septica
    • Wu PL, Rao KV, Su CH, Kuoh CS, Wu TS. Phenanthroindolizidine alkaloids and their cytotoxicity from the leaves of Ficus septica. Heterocycles 2002; 57: 2401-2408
    • (2002) Heterocycles , vol.57 , pp. 2401-2408
    • Wu, P.L.1    Rao, K.V.2    Su, C.H.3    Kuoh, C.S.4    Wu, T.S.5
  • 18
    • 0742323464 scopus 로고    scopus 로고
    • On-line identification of phenanthroindolizidine alkaloids in a crude extract from Tylophora atrofolliculata by liquid chromatography combined with tandem mass spectrometry
    • Cui L, Abliz Z, Xia M, Zhao L, Gao S, He W, Xiang Y, Liang F, Yu SS. On-line identification of phenanthroindolizidine alkaloids in a crude extract from Tylophora atrofolliculata by liquid chromatography combined with tandem mass spectrometry. Rapid Commun Mass Spectrom 2004; 18: 184-190
    • (2004) Rapid Commun Mass Spectrom , vol.18 , pp. 184-190
    • Cui, L.1    Abliz, Z.2    Xia, M.3    Zhao, L.4    Gao, S.5    He, W.6    Xiang, Y.7    Liang, F.8    Yu, S.S.9
  • 19
    • 0036023999 scopus 로고    scopus 로고
    • Study of structural characteristic features of phenanthroindolizidine alkaloids by fast atom bombardment with tandemmass spectrometry
    • Xiang Y, Abliz Z, Li LJ, Huang XS, Yu SS. Study of structural characteristic features of phenanthroindolizidine alkaloids by fast atom bombardment with tandemmass spectrometry. Rapid CommunMass Spectrom 2002; 16: 1668-1674
    • (2002) Rapid CommunMass Spectrom , vol.16 , pp. 1668-1674
    • Xiang, Y.1    Abliz, Z.2    Li, L.J.3    Huang, X.S.4    Yu, S.S.5
  • 21
    • 0026676055 scopus 로고
    • The application of circular dichroism on the structure analysis of natural products - Diterpenoid dilactones and tylophorines
    • Mi JF, Fang SD, Chen Y, Xu YM, Zhang R. The application of circular dichroism on the structure analysis of natural products - diterpenoid dilactones and tylophorines. Acta Pharm Sin 1992; 27: 197-203
    • (1992) Acta Pharm Sin , vol.27 , pp. 197-203
    • Mi, J.F.1    Fang, S.D.2    Chen, Y.3    Xu, Y.M.4    Zhang, R.5
  • 23
    • 0028245591 scopus 로고
    • New phenanthroindolizidine N-oxides alkaloids isolated from Vincetoxicum hirudinaria Medic
    • Lavault M, Richomme P, Bruneton J. New phenanthroindolizidine N-oxides alkaloids isolated from Vincetoxicum hirudinaria Medic. Pharm Acta Helv 1994; 68: 225-227
    • (1994) Pharm Acta Helv , vol.68 , pp. 225-227
    • Lavault, M.1    Richomme, P.2    Bruneton, J.3
  • 24
    • 17544380761 scopus 로고    scopus 로고
    • Cytotoxicity activity of some phenanthroindolizidine N-oxide alkaloids from Cynanchum vincetoxicum
    • Stærk D, Christensen J, Lemmich E, Duus JØ, Olsen CE, Jaroszewski JW. Cytotoxicity activity of some phenanthroindolizidine N-oxide alkaloids from Cynanchum vincetoxicum. J Nat Prod 2000; 63: 1584-1586
    • (2000) J Nat Prod , vol.63 , pp. 1584-1586
    • Stærk, D.1    Christensen, J.2    Lemmich, E.3    Duus J.Ø4    Olsen, C.E.5    Jaroszewski, J.W.6
  • 25
    • 0021053335 scopus 로고
    • Amino acids as chiral educts for asymmetric products. Chirally specific syntheses of tylophorine and cryptopleurine
    • Buckley FT, Rapoport H. Amino acids as chiral educts for asymmetric products. Chirally specific syntheses of tylophorine and cryptopleurine. J Org Chem 1983; 48: 4222-4232
    • (1983) J Org Chem , vol.48 , pp. 4222-4232
    • Buckley, F.T.1    Rapoport, H.2
  • 27
    • 2642573409 scopus 로고    scopus 로고
    • Cytotoxic alkaloids from the roots of Tylophora atrofolliculata
    • Huang X, Gao S, Fan L, Yu S, Liang X. Cytotoxic alkaloids from the roots of Tylophora atrofolliculata. Planta Med 2004; 70: 441-445
    • (2004) Planta Med , vol.70 , pp. 441-445
    • Huang, X.1    Gao, S.2    Fan, L.3    Yu, S.4    Liang, X.5
  • 28
    • 0018823130 scopus 로고
    • Structural determinants responsible for the biological activity of (-)-emetine, (-)-cryptopleurine, and (-)-tylocrebrine: Structure-activity relationship among related compounds
    • Gupta RS, Krepinsky JJ, Siminovitch I. Structural determinants responsible for the biological activity of (-)-emetine, (-)-cryptopleurine, and (-)-tylocrebrine: structure-activity relationship among related compounds. Mol Pharmacol 1980; 18: 136-143
    • (1980) Mol Pharmacol , vol.18 , pp. 136-143
    • Gupta, R.S.1    Krepinsky, J.J.2    Siminovitch, I.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.