-
1
-
-
0027475568
-
Interstitial-lymphatic mechanisms in the control of extracellular fluid volume
-
Aukland K, Reed RK. Interstitial-lymphatic mechanisms in the control of extracellular fluid volume. Physiol Rev 1993;73:1-78.
-
(1993)
Physiol Rev
, vol.73
, pp. 1-78
-
-
Aukland, K.1
Reed, R.K.2
-
2
-
-
33344463349
-
Discovery of vascular permeability factor (VPF)
-
Dvorak HF. Discovery of vascular permeability factor (VPF). Exp Cell Res 2006;312:522-526.
-
(2006)
Exp Cell Res
, vol.312
, pp. 522-526
-
-
Dvorak, H.F.1
-
4
-
-
25644449640
-
Pathophysiological consequences of VEGF-induced vascular permeability
-
Weis SM, Cheresh DA. Pathophysiological consequences of VEGF-induced vascular permeability. Nature 2005;437:497-504.
-
(2005)
Nature
, vol.437
, pp. 497-504
-
-
Weis, S.M.1
Cheresh, D.A.2
-
5
-
-
0001612420
-
Molecular recognition of the extracellular matrix by cell surface receptors
-
Comper WD, ed, Reading, UK: Harwood Academic Publishers
-
Rubin K, Gullberg D, Tomasini-Johansson B, Reed RK, Rydén C, Borg TK. Molecular recognition of the extracellular matrix by cell surface receptors. In: Comper WD, ed. Extracellular Matrix, Vol. 2, Molecular Components and Interactions. Reading, UK: Harwood Academic Publishers, 1996:262-309.
-
(1996)
Extracellular Matrix, Vol. 2, Molecular Components and Interactions
, pp. 262-309
-
-
Rubin, K.1
Gullberg, D.2
Tomasini-Johansson, B.3
Reed, R.K.4
Rydén, C.5
Borg, T.K.6
-
6
-
-
0035033319
-
Control of interstitial fluid pressure: Role of β1-integrins
-
Reed RK, Berg A, Gjerde EA, Rubin K. Control of interstitial fluid pressure: role of β1-integrins. Semin Nephrol 2001;21:222-230.
-
(2001)
Semin Nephrol
, vol.21
, pp. 222-230
-
-
Reed, R.K.1
Berg, A.2
Gjerde, E.A.3
Rubin, K.4
-
7
-
-
12244298243
-
New and active role of the interstitium in control of interstitial fluid pressure: Potential therapeutic consequences
-
Wiig H, Rubin K, Reed RK. New and active role of the interstitium in control of interstitial fluid pressure: potential therapeutic consequences. Acta Anaesthesiol Scand 2003;47:111-121.
-
(2003)
Acta Anaesthesiol Scand
, vol.47
, pp. 111-121
-
-
Wiig, H.1
Rubin, K.2
Reed, R.K.3
-
8
-
-
0020694681
-
Macromolecular basis of globular protein exclusion and of swelling pressure in loose connective tissue (umbilical cord)
-
Meyer FA. Macromolecular basis of globular protein exclusion and of swelling pressure in loose connective tissue (umbilical cord). Biochem Biophys Acta 1983;755:388-399.
-
(1983)
Biochem Biophys Acta
, vol.755
, pp. 388-399
-
-
Meyer, F.A.1
-
9
-
-
0032754561
-
Effect of tumor necrosis factor-α, IL-1β, and IL-6 on interstitial fluid pressure in rat skin
-
Nedrebø T, Berg A, Reed RK. Effect of tumor necrosis factor-α, IL-1β, and IL-6 on interstitial fluid pressure in rat skin. Am J Physiol 1999;277:H1857-1862.
-
(1999)
Am J Physiol
, vol.277
-
-
Nedrebø, T.1
Berg, A.2
Reed, R.K.3
-
10
-
-
0031990585
-
Effect of PGE1, PGI2, and PGF2a analogs on collagen gel compaction in vitro and interstitial pressure in vivo
-
Berg A, Ekwall, AK, Rubin K, Stjernschantz J, Reed RK. Effect of PGE1, PGI2, and PGF2a analogs on collagen gel compaction in vitro and interstitial pressure in vivo. Am J Physiol 1998;274:H663-671.
-
(1998)
Am J Physiol
, vol.274
-
-
Berg, A.1
Ekwall, A.K.2
Rubin, K.3
Stjernschantz, J.4
Reed, R.K.5
-
11
-
-
0028171308
-
The anti-inflammatory agent a-trinositol exerts its edema-preventing effects through modulation of β1 integrin function
-
Rodt SÅ, Reed RK, Ljungström M, Gustafsson TO, Rubin K. The anti-inflammatory agent a-trinositol exerts its edema-preventing effects through modulation of β1 integrin function. Circ Res 1994;75:942-948.
-
(1994)
Circ Res
, vol.75
, pp. 942-948
-
-
Rodt, S.Å.1
Reed, R.K.2
Ljungström, M.3
Gustafsson, T.O.4
Rubin, K.5
-
13
-
-
0029824569
-
A novel physiological function for platelet-derived growth factor-BB in rat dermis
-
Rodt SÅ, Åhlen K, Berg A, Rubin K, Reed RK. A novel physiological function for platelet-derived growth factor-BB in rat dermis. J Physiol (London) 1996;495:193-200.
-
(1996)
J Physiol (London)
, vol.495
, pp. 193-200
-
-
Rodt, S.Å.1
Åhlen, K.2
Berg, A.3
Rubin, K.4
Reed, R.K.5
-
14
-
-
0033613119
-
Platelet-derived growth factor beta receptor regulates interstitial fluid homeostasis through phosphatidylinositol-3' kinase signaling
-
Heuchel R, Berg A, Tallquist M, et al. Platelet-derived growth factor beta receptor regulates interstitial fluid homeostasis through phosphatidylinositol-3' kinase signaling. Proc Natl Acad Sci USA 1999;96:11410-11415.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 11410-11415
-
-
Heuchel, R.1
Berg, A.2
Tallquist, M.3
-
15
-
-
2942676788
-
The PDGF family: Four gene products form five dimeric isoforms
-
Fredriksson L, Li H, Eriksson U. The PDGF family: four gene products form five dimeric isoforms. Cytokine Growth Factor Rev 2004;15:197-204.
-
(2004)
Cytokine Growth Factor Rev
, vol.15
, pp. 197-204
-
-
Fredriksson, L.1
Li, H.2
Eriksson, U.3
-
17
-
-
0031740739
-
Cell interactions with collagen matrices in vivo and in vitro depend on phosphatidylinositol 3-kinase and free cytoplasmic calcium
-
Åhlen K, Berg A, Stiger F, et al. Cell interactions with collagen matrices in vivo and in vitro depend on phosphatidylinositol 3-kinase and free cytoplasmic calcium. Cell Adhes Commun 1998;5:461-473.
-
(1998)
Cell Adhes Commun
, vol.5
, pp. 461-473
-
-
Åhlen, K.1
Berg, A.2
Stiger, F.3
-
18
-
-
0026802361
-
Blockade of β1-integrins in skin causes edema through lowering of interstitial fluid pressure
-
Reed RK, Rubin K, Wiig H, Rodt SÅ. Blockade of β1-integrins in skin causes edema through lowering of interstitial fluid pressure. Circ Res 1992;71:978-983.
-
(1992)
Circ Res
, vol.71
, pp. 978-983
-
-
Reed, R.K.1
Rubin, K.2
Wiig, H.3
Robt, S.Å.4
-
19
-
-
0037145037
-
Integrins: Bidirectional, allosteric signaling machines
-
Hynes RO. Integrins: bidirectional, allosteric signaling machines. Cell 2002;110:673-687.
-
(2002)
Cell
, vol.110
, pp. 673-687
-
-
Hynes, R.O.1
-
20
-
-
0036222549
-
Sensing the environment: A historical perspective on integrin signal transduction
-
Miranti CK, Brugge JS. Sensing the environment: a historical perspective on integrin signal transduction. Nat Cell Biol 2002;4:E83-90.
-
(2002)
Nat Cell Biol
, vol.4
-
-
Miranti, C.K.1
Brugge, J.S.2
-
21
-
-
0028335948
-
Anchorage dependence, integrins, and apoptosis
-
Ruoslahti E, Reed JC. Anchorage dependence, integrins, and apoptosis. Cell 1994;77:477-478.
-
(1994)
Cell
, vol.77
, pp. 477-478
-
-
Ruoslahti, E.1
Reed, J.C.2
-
23
-
-
0036229694
-
Networks and crosstalk: Integrin signalling spreads
-
Schwartz MA, Ginsberg MH. Networks and crosstalk: integrin signalling spreads. Nat Cell Biol 2002;4:E65-68.
-
(2002)
Nat Cell Biol
, vol.4
-
-
Schwartz, M.A.1
Ginsberg, M.H.2
-
24
-
-
33645296886
-
Platelet-derived growth factor BB-mediated normalization of dermal interstitial fluid pressure after mast cell degranulation depends on β3 but not β1 integrins
-
Liden Å, Berg A, Nedrebø T, Reed RK, Rubin K. Platelet-derived growth factor BB-mediated normalization of dermal interstitial fluid pressure after mast cell degranulation depends on β3 but not β1 integrins. Circ Res 2006;98:635-641.
-
(2006)
Circ Res
, vol.98
, pp. 635-641
-
-
Å, L.1
Berg, A.2
Nedrebø, T.3
Reed, R.K.4
Rubin, K.5
-
25
-
-
0038738331
-
Fibroblast biology in three-dimensional collagen matrices
-
Grinnell F. Fibroblast biology in three-dimensional collagen matrices. Trends Cell Biol 2003;13:264-269.
-
(2003)
Trends Cell Biol
, vol.13
, pp. 264-269
-
-
Grinnell, F.1
-
26
-
-
0019459687
-
Fibroblast traction as a mechanism for collagen morphogenesis
-
Harris AK, Stopak D, Wild P. Fibroblast traction as a mechanism for collagen morphogenesis. Nature 1981;290:249-251.
-
(1981)
Nature
, vol.290
, pp. 249-251
-
-
Harris, A.K.1
Stopak, D.2
Wild, P.3
-
27
-
-
0035002155
-
Force and focal adhesion assembly: A close relationship studied using elastic micropatterned substrates
-
Balaban NQ, Schwarz US, Riveline D, et al. Force and focal adhesion assembly: a close relationship studied using elastic micropatterned substrates. Nat Cell Biol 2001;3:466-472.
-
(2001)
Nat Cell Biol
, vol.3
, pp. 466-472
-
-
Balaban, N.Q.1
Schwarz, U.S.2
Riveline, D.3
-
28
-
-
0033527692
-
Focal adhesion motility revealed in stationary fibroblasts
-
Smilenov LB, Mikhailov A, Pelham RJ, Marcantonio EE, Gundersen GG. Focal adhesion motility revealed in stationary fibroblasts. Science 1999;286:1172-1174.
-
(1999)
Science
, vol.286
, pp. 1172-1174
-
-
Smilenov, L.B.1
Mikhailov, A.2
Pelham, R.J.3
Marcantonio, E.E.4
Gundersen, G.G.5
-
29
-
-
0025178575
-
β1 Integrin-mediated collagen gel contraction is stimulated by PDGF
-
Gullberg D, Tingström A, Thuresson AC, et al. β1 Integrin-mediated collagen gel contraction is stimulated by PDGF. Exp Cell Res 1990;186:264-272.
-
(1990)
Exp Cell Res
, vol.186
, pp. 264-272
-
-
Gullberg, D.1
Tingström, A.2
Thuresson, A.C.3
-
31
-
-
0033864576
-
Contraction of collagen matrices mediated by α2β1A and αVβ3 integrins
-
Cooke ME, Sakai T, Mosher DF. Contraction of collagen matrices mediated by α2β1A and αVβ3 integrins. J Cell Sci 2000;113:2375-2383.
-
(2000)
J Cell Sci
, vol.113
, pp. 2375-2383
-
-
Cooke, M.E.1
Sakai, T.2
Mosher, D.F.3
-
32
-
-
0344010157
-
Integrin aVb3 mediates plateletderived growth factor-BB-stimulated collagen gel contraction in cells expressing signaling deficient integrin α2β1
-
Grundström G, Mosher DF, Sakai T, Rubin K. Integrin aVb3 mediates plateletderived growth factor-BB-stimulated collagen gel contraction in cells expressing signaling deficient integrin α2β1. Exp Cell Res 2003;291:463-473.
-
(2003)
Exp Cell Res
, vol.291
, pp. 463-473
-
-
Grundström, G.1
Mosher, D.F.2
Sakai, T.3
Rubin, K.4
-
33
-
-
0024450186
-
Platelet isoforms of platelet-derived growth factor stimulate fibroblasts to contract collagen matrices
-
Clark RA, Folkvord JM, Hart CE, Murray MJ, McPherson JM. Platelet isoforms of platelet-derived growth factor stimulate fibroblasts to contract collagen matrices. J Clin Invest 1989;84:1036-1040.
-
(1989)
J Clin Invest
, vol.84
, pp. 1036-1040
-
-
Clark, R.A.1
Folkvord, J.M.2
Hart, C.E.3
Murray, M.J.4
McPherson, J.M.5
-
34
-
-
0026664282
-
Regulation of fibroblast-mediated collagen gel contraction by platelet-derived growth factor, interleukin-1a and transforming growth factor-β1
-
Tingström A, Heldin C-H, Rubin K. Regulation of fibroblast-mediated collagen gel contraction by platelet-derived growth factor, interleukin-1a and transforming growth factor-β1. J Cell Sci 1992;102:315-322.
-
(1992)
J Cell Sci
, vol.102
, pp. 315-322
-
-
Tingström, A.1
Heldin, C.-H.2
Rubin, K.3
-
35
-
-
0022891340
-
Tumors: Wounds that do not heal. Similarities between tumor stroma generation and wound healing
-
Dvorak HF. Tumors: wounds that do not heal. Similarities between tumor stroma generation and wound healing. N Engl J Med 1986;315:1650-1659.
-
(1986)
N Engl J Med
, vol.315
, pp. 1650-1659
-
-
Dvorak, H.F.1
-
36
-
-
0347123433
-
Tumour-educated macrophages promote tumour progression and metastasis
-
Pollard JW. Tumour-educated macrophages promote tumour progression and metastasis. Nat Rev Cancer 2004;4:71-78.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 71-78
-
-
Pollard, J.W.1
-
37
-
-
9244227134
-
Stromal fibroblasts in cancer initiation and progression
-
Bhowmick NA, Neilson EG, Moses HL. Stromal fibroblasts in cancer initiation and progression. Nature 2004;432:332-337.
-
(2004)
Nature
, vol.432
, pp. 332-337
-
-
Bhowmick, N.A.1
Neilson, E.G.2
Moses, H.L.3
-
38
-
-
0346365485
-
Natural mechanisms protecting against cancer
-
Jakobisiak M, Lasek W, Golab J. Natural mechanisms protecting against cancer. Immunol Lett 2003;90:103-122.
-
(2003)
Immunol Lett
, vol.90
, pp. 103-122
-
-
Jakobisiak, M.1
Lasek, W.2
Golab, J.3
-
39
-
-
0036187615
-
The role of tumour-associated macrophages in tumour progression: Implications for new anticancer therapies
-
Bingle L, Brown NJ, Lewis CE. The role of tumour-associated macrophages in tumour progression: implications for new anticancer therapies. J Pathol 2002;196:254-265.
-
(2002)
J Pathol
, vol.196
, pp. 254-265
-
-
Bingle, L.1
Brown, N.J.2
Lewis, C.E.3
-
40
-
-
0037418208
-
IL-1 is required for tumor invasiveness and angiogenesis
-
Voronov E, Shouval DS, Krelin Y, et al. IL-1 is required for tumor invasiveness and angiogenesis. Proc Natl Acad Sci USA 2003;100:2645-2650.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 2645-2650
-
-
Voronov, E.1
Shouval, D.S.2
Krelin, Y.3
-
41
-
-
0028470454
-
Barriers to drug delivery in solid tumors
-
Jain RK. Barriers to drug delivery in solid tumors. Sci Am 1994;271:58-65.
-
(1994)
Sci Am
, vol.271
, pp. 58-65
-
-
Jain, R.K.1
-
42
-
-
0026650318
-
Interstitial hypertension in head and neck tumors in patients: Correlation with tumor size
-
Gutmann R, Leunig M, Feyh J, et al. Interstitial hypertension in head and neck tumors in patients: correlation with tumor size. Cancer Res 1992;52:1993-1995.
-
(1992)
Cancer Res
, vol.52
, pp. 1993-1995
-
-
Gutmann, R.1
Leunig, M.2
Feyh, J.3
-
43
-
-
0033635842
-
Hyaluronidaseinduced periodic modulation of the interstitial fluid pressure increases selective antibody uptake in human osteosarcoma xenografts
-
Brekken C, Hjelstuen MH, Bruland OS, deLange Davies C. Hyaluronidaseinduced periodic modulation of the interstitial fluid pressure increases selective antibody uptake in human osteosarcoma xenografts. Anticancer Res 2000;20:3513-3519.
-
(2000)
Anticancer Res
, vol.20
, pp. 3513-3519
-
-
Brekken, C.1
Hjelstuen, M.H.2
Bruland, O.S.3
Davies, C.D.4
-
44
-
-
0023219734
-
Transport of molecules in the tumor interstitium: A review
-
Jain RK. Transport of molecules in the tumor interstitium: a review. Cancer Res 1987;47:3039-3051.
-
(1987)
Cancer Res
, vol.47
, pp. 3039-3051
-
-
Jain, R.K.1
-
45
-
-
0034662608
-
Absence of functional lymphatics within a murine sarcoma: A molecular and functional evaluation
-
Leu AJ, Berk DA, Lymboussaki A, Alitalo K, Jain RK. Absence of functional lymphatics within a murine sarcoma: a molecular and functional evaluation. Cancer Res 2000;60:4324-4327.
-
(2000)
Cancer Res
, vol.60
, pp. 4324-4327
-
-
Leu, A.J.1
Berk, D.A.2
Lymboussaki, A.3
Alitalo, K.4
Jain, R.K.5
-
46
-
-
0034648765
-
Angiogenesis in cancer and other diseases
-
Carmeliet P, Jain RK. Angiogenesis in cancer and other diseases. Nature 2000;407:249-257.
-
(2000)
Nature
, vol.407
, pp. 249-257
-
-
Carmeliet, P.1
Jain, R.K.2
-
47
-
-
0035689646
-
Tumor physiology and drug resistance
-
Tannock IF. Tumor physiology and drug resistance. Cancer Metastasis Rev 2001;20:123-132.
-
(2001)
Cancer Metastasis Rev
, vol.20
, pp. 123-132
-
-
Tannock, I.F.1
-
48
-
-
0034059160
-
Lowering of tumoral interstitial fluid pressure by prostaglandin E1 is paralleled by an increased uptake of 51Cr-EDTA
-
Rubin K, Sjöquist M, Gustafsson AM, Isaksson B, Salvessen G, Reed RK. Lowering of tumoral interstitial fluid pressure by prostaglandin E1 is paralleled by an increased uptake of 51Cr-EDTA. Int J Cancer 2000;86:636-643.
-
(2000)
Int J Cancer
, vol.86
, pp. 636-643
-
-
Rubin, K.1
Sjöquist, M.2
Gustafsson, A.M.3
Isaksson, B.4
Salvessen, G.5
Reed, R.K.6
-
49
-
-
0035141292
-
Bradykinin modulation of tumor vasculature: I. Activation of B2 receptors increases delivery of chemotherapeutic agents into solid peripheral tumors, enhancing their efficacy
-
Emerich, DF, Snodgrass P, Dean RL, et al. Bradykinin modulation of tumor vasculature: I. Activation of B2 receptors increases delivery of chemotherapeutic agents into solid peripheral tumors, enhancing their efficacy. J Pharmacol Exp Ther 2001;296:623-631.
-
(2001)
J Pharmacol Exp Ther
, vol.296
, pp. 623-631
-
-
Emerich, D.F.1
Snodgrass, P.2
Dean, R.L.3
-
50
-
-
0035297541
-
Inhibition of platelet-derived growth factor receptors reduces interstitial hypertension and increases transcapillary transport in tumors
-
Pietras K, Östman A, Sjöquist M, et al. Inhibition of platelet-derived growth factor receptors reduces interstitial hypertension and increases transcapillary transport in tumors. Cancer Res 2001;61:2929-2934.
-
(2001)
Cancer Res
, vol.61
, pp. 2929-2934
-
-
Pietras, K.1
Östman, A.2
Sjöquist, M.3
-
51
-
-
0037058575
-
Interference with TGF-κ1 and -β3 in tumor stroma lowers tumor interstitial fluid pressure independently of growth in experimental carcinoma
-
Lammerts E, Roswall P, Sundberg C, et al. Interference with TGF-κ1 and -β3 in tumor stroma lowers tumor interstitial fluid pressure independently of growth in experimental carcinoma. Int J Cancer 2002;102:453.462.
-
(2002)
Int J Cancer
, vol.102
, pp. 453462
-
-
Lammerts, E.1
Roswall, P.2
Sundberg, C.3
-
52
-
-
0034306974
-
Anti-vascular endothelial growth factor treatment augments tumor radiation response under normoxic or hypoxic conditions
-
Lee CG, Heijn M, diTomaso E, et al. Anti-vascular endothelial growth factor treatment augments tumor radiation response under normoxic or hypoxic conditions. Cancer Res 2000;60:5565.5570.
-
(2000)
Cancer Res
, vol.60
, pp. 55655570
-
-
Lee, C.G.1
Heijn, M.2
DiTomaso, E.3
-
53
-
-
0027429968
-
Dexamethasone reduces the interstitial fluid pressure in a human colon adenocarcinoma xenograft
-
Kristjansen PE, Boucher Y, Jain RK. Dexamethasone reduces the interstitial fluid pressure in a human colon adenocarcinoma xenograft. Cancer Res 1993;53:4764-4766.
-
(1993)
Cancer Res
, vol.53
, pp. 4764-4766
-
-
Kristjansen, P.E.1
Boucher, Y.2
Jain, R.K.3
-
54
-
-
0141706804
-
Lowering of tumor interstitial fluid pressure specifically augments efficacy of chemotherapy
-
Salnikov AV, Iversen VV, Koisti M, et al. Lowering of tumor interstitial fluid pressure specifically augments efficacy of chemotherapy. FASEB J 2003;17:1756.1758.
-
(2003)
FASEB J
, vol.17
, pp. 17561758
-
-
Salnikov, A.V.1
Iversen, V.V.2
Koisti, M.3
-
55
-
-
0036790060
-
Inhibition of PDGF receptor signaling in tumor stroma enhances antitumor effect of chemotherapy
-
Pietras K, Rubin K, Sjoblom T, et al. Inhibition of PDGF receptor signaling in tumor stroma enhances antitumor effect of chemotherapy. Cancer Res 2002;62:5476. 5484.
-
(2002)
Cancer Res
, vol.62
, pp. 5476-5484
-
-
Pietras, K.1
Rubin, K.2
Sjoblom, T.3
-
56
-
-
11144354392
-
Direct evidence that the VEGF-specific antibody bevacizumab has antivascular effects in human rectal cancer
-
Willett CG. Boucher Y, DiTomaso E, et al. Direct evidence that the VEGF-specific antibody bevacizumab has antivascular effects in human rectal cancer. Nat Med 2004;10:145.147.
-
(2004)
Nat Med
, vol.10
, pp. 145147
-
-
Willett, C.G.1
Boucher, Y.2
DiTomaso, E.3
-
57
-
-
17144428081
-
Inhibition of TGF-β modulates macrophages and vessel maturation in parallel to a lowering of interstitial fluid pressure in experimental carcinoma
-
Salnikov AV, Roswall P, Sundberg C, Gardner H, Heldin N-E, Rubin K. Inhibition of TGF-β modulates macrophages and vessel maturation in parallel to a lowering of interstitial fluid pressure in experimental carcinoma. Lab Invest 2005;85:512. 521.
-
(2005)
Lab Invest
, vol.85
, pp. 512-521
-
-
Salnikov, A.V.1
Roswall, P.2
Sundberg, C.3
Gardner, H.4
Heldin, N.-E.5
Rubin, K.6
|