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Volumn 48, Issue 10, 2009, Pages 1208-1212
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Sulfasalazine blocks the release of proteoglycan and collagen from cytokine stimulated cartilage and down-regulates metalloproteinases.
a
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Author keywords
[No Author keywords available]
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Indexed keywords
ANTIRHEUMATIC AGENT;
COLLAGEN;
INTERLEUKIN 1ALPHA;
METALLOPROTEINASE;
NONSTEROID ANTIINFLAMMATORY AGENT;
ONCOSTATIN M;
PROTEOGLYCAN;
SALAZOSULFAPYRIDINE;
ANIMAL;
ARTICLE;
ARTICULAR CARTILAGE;
BIOSYNTHESIS;
CATTLE;
CELL CULTURE;
CULTURE MEDIUM;
DOSE RESPONSE;
DOWN REGULATION;
DRUG ANTAGONISM;
DRUG EFFECT;
DRUG SCREENING;
GENE EXPRESSION REGULATION;
HUMAN;
HYALINE CARTILAGE;
KNEE OSTEOARTHRITIS;
METABOLISM;
METHODOLOGY;
NOSE CARTILAGE;
ANIMALS;
ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL;
ANTIRHEUMATIC AGENTS;
CARTILAGE, ARTICULAR;
CATTLE;
CELLS, CULTURED;
COLLAGEN;
CULTURE MEDIA, CONDITIONED;
DOSE-RESPONSE RELATIONSHIP, DRUG;
DOWN-REGULATION;
DRUG EVALUATION, PRECLINICAL;
GENE EXPRESSION REGULATION, ENZYMOLOGIC;
HUMANS;
HYALINE CARTILAGE;
INTERLEUKIN-1ALPHA;
METALLOPROTEASES;
NASAL CARTILAGES;
ONCOSTATIN M;
OSTEOARTHRITIS, KNEE;
PROTEOGLYCANS;
SULFASALAZINE;
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EID: 70350782465
PISSN: None
EISSN: 14620332
Source Type: Journal
DOI: 10.1093/rheumatology/kep236 Document Type: Article |
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Times cited : (15)
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References (0)
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