Molecular dynamics simulations of the conformational changes in signal transducers and activators of transcription, Stat1 and Stat3

Journal of Molecular Graphics and Modelling

Volumn 28, Issue 4, 2009, Pages 347-356

  Lin, Jianping ^a   Buettner, Ralf ^a   Yuan, Yate Ching ^a   Yip, Richard ^a   Horne, David ^a   Jove, Richard ^a   Vaidehi, Nagarajan ^a  

^a CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

Author keywords

Clustering; Correlation map; Domain motion; Druggable pocket; Molecular dynamics; Signal transducers and activators of transcription

Indexed keywords

CLUSTERING; CORRELATION MAP; DOMAIN MOTION; DRUGGABLE POCKET; SIGNAL TRANSDUCERS AND ACTIVATORS OF TRANSCRIPTION;

BIOACTIVITY; CONFORMATIONS; DYNAMICS; MOLECULAR DYNAMICS; MONOMERS; NUCLEIC ACIDS; PIEZOELECTRIC TRANSDUCERS; POLYPEPTIDES; SIMULATORS; TRANSCRIPTION FACTORS;

TRANSCRIPTION;

DNA; HOMODIMER; MONOMER; PROTEIN SH2; STAT1 PROTEIN; STAT3 PROTEIN; WATER;

ARTICLE; CONFORMATIONAL TRANSITION; DIFFUSION; DRUG STRUCTURE; GENE EXPRESSION REGULATION; MODEL; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN DOMAIN; PROTEIN FAMILY; SIGNAL TRANSDUCTION; SIMULATION;

CARBON; COMPUTER SIMULATION; DIFFUSION; DNA; HUMANS; MOLECULAR DYNAMICS SIMULATION; PLIABILITY; PRINCIPAL COMPONENT ANALYSIS; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; SOLVENTS; STAT1 TRANSCRIPTION FACTOR; STAT2 TRANSCRIPTION FACTOR; THERMODYNAMICS; TIME FACTORS;

EID: 70350776501     PISSN: 10933263     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmgm.2009.08.013     Document Type: Article

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