Levels of Circulating Pro-angiogenic Cells Predict Cardiovascular Outcomes in Patients With Chronic Heart Failure

Journal of Cardiac Failure

Volumn 15, Issue 9, 2009, Pages 747-755

  Balconi, Giovanna ^a   Lehmann, Ralf ^b   Fiordaliso, Fabio ^a   Assmus, Birgit ^b   Dimmeler, Stefanie ^b   Sarto, Patrizio ^c   Carbonieri, Emanuele ^c   Gualco, Alessandra ^d   Campana, Carlo ^e   Angelici, Laura ^a   Masson, Serge ^a   Mohammed, Salman Aa ^a   Dejana, Elisabetta ^a,f,g   Gorini, Marco ^h   Zeiher, Andreas M ^b   Latini, Roberto ^a,i  

^a MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

^b GOETHE UNIVERSITY   (Germany)

^c Ospedale Civile   (Italy)

^d IRCCS   (Italy)

^e FONDAZIONE IRCCS POLICLINICO SAN MATTEO   (Italy)

^f FIRC INSTITUTE OF MOLECULAR ONCOLOGY   (Italy)

^g UNIVERSITY OF MILAN   (Italy)

^h ANMCO RESEARCH CENTER   (Italy)

ⁱ NEW YORK MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CREATININE; CYANINE DYE; FLUORESCEIN ISOTHIOCYANATE; LOW DENSITY LIPOPROTEIN; NATRIURETIC FACTOR; TETRAMETHYLINDOCARBOCYANINE; UNCLASSIFIED DRUG;

ADULT; ARTICLE; BLOOD SAMPLING; CARDIOVASCULAR RISK; CELL COUNT; CELL CULTURE; CIRCULATION; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; HEART FAILURE; HOSPITALIZATION; HUMAN; MALE; MONONUCLEAR CELL; MORTALITY; OUTCOME ASSESSMENT; PRIORITY JOURNAL; SURVIVAL RATE;

ADULT; AGED; BIOLOGICAL MARKERS; CELLS, CULTURED; COCULTURE TECHNIQUES; ENDOTHELIUM, VASCULAR; FEMALE; HEART FAILURE; HUMANS; LEUKOCYTES, MONONUCLEAR; MALE; MIDDLE AGED; NEOVASCULARIZATION, PATHOLOGIC; PREDICTIVE VALUE OF TESTS; RISK FACTORS; TREATMENT OUTCOME;

EID: 70350754645     PISSN: 10719164     EISSN: 15328414     Source Type: Journal    
DOI: 10.1016/j.cardfail.2009.05.011     Document Type: Article

References (28)

1. Vasa M., Fichtlscherer S., Aicher A., et al. Number and migratory activity of circulating endothelial progenitor cells inversely correlate with risk factors for coronary artery disease. Circ Res 89 (2001) E1-E7
2. Loomans C.J., de Koning E.J., Staal F.J., et al. Endothelial progenitor cell dysfunction: a novel concept in the pathogenesis of vascular complications of type 1 diabetes. Diabetes 53 (2004) 195-199
3. Tepper O.M., Galiano R.D., Capla J.M., et al. Human endothelial progenitor cells from type II diabetics exhibit impaired proliferation, adhesion, and incorporation into vascular structures. Circulation 106 (2002) 2781-2786
4. Hill J.M., Zalos G., Halcox J.P., et al. Circulating endothelial progenitor cells, vascular function, and cardiovascular risk. N Engl J Med 348 (2003) 593-600
5. Schmidt-Lucke C., Rossig L., Fichtlscherer S., et al. Reduced number of circulating endothelial progenitor cells predicts future cardiovascular events: proof of concept for the clinical importance of endogenous vascular repair. Circulation 111 (2005) 2981-2987
6. Werner N., Kosiol S., Schiegl T., et al. Circulating endothelial progenitor cells and cardiovascular outcomes. N Engl J Med 353 (2005) 999-1007
7. Heeschen C., Aicher A., Lehmann R., et al. Erythropoietin is a potent physiologic stimulus for endothelial progenitor cell mobilization. Blood 102 (2003) 1340-1346
8. Landmesser U., Engberding N., Bahlmann F.H., et al. Statin-induced improvement of endothelial progenitor cell mobilization, myocardial neovascularization, left ventricular function, and survival after experimental myocardial infarction requires endothelial nitric oxide synthase. Circulation 110 (2004) 1933-1939
9. Valgimigli M., Rigolin G.M., Fucili A., et al. CD34+ and endothelial progenitor cells in patients with various degrees of congestive heart failure. Circulation 110 (2004) 1209-1212
10. Nonaka-Sarukawa M., Yamamoto K., Aoki H., et al. Circulating endothelial progenitor cells in congestive heart failure. Int J Cardiol 119 (2007) 344-348
11. Kissel C.K., Lehmann R., Assmus B., et al. Selective functional exhaustion of hematopoietic progenitor cells in the bone marrow of patients with postinfarction heart failure. J Am Coll Cardiol 49 (2007) 2341-2349
12. Michowitz Y., Goldstein E., Wexler D., Sheps D., Keren G., and George J. Circulating endothelial progenitor cells and clinical outcome in patients with congestive heart failure. Heart 93 (2007) 1046-1050
13. Latini R., Masson S., Anand I., et al. Effects of valsartan on circulating brain natriuretic peptide and norepinephrine in symptomatic chronic heart failure: the Valsartan Heart Failure Trial (Val-HeFT). Circulation 106 (2002) 2454-2458
14. Asahara T., Masuda H., Takahashi T., et al. Bone marrow origin of endothelial progenitor cells responsible for postnatal vasculogenesis in physiological and pathological neovascularization. Circ Res 85 (1999) 221-228
15. Carmeliet P. Mechanisms of angiogenesis and arteriogenesis. Nat Med 6 (2000) 389-395
16. Schmidt A., Brixius K., and Bloch W. Endothelial precursor cell migration during vasculogenesis. Circ Res 101 (2007) 125-136
17. Asahara T., Murohara T., Sullivan A., et al. Isolation of putative progenitor endothelial cells for angiogenesis. Science 275 (1997) 964-967
18. Rehman J., Li J., Orschell C.M., and March K.L. Peripheral blood "endothelial progenitor cells" are derived from monocyte/macrophages and secrete angiogenic growth factors. Circulation 107 (2003) 1164-1169
19. Dome B., Dobos J., Tovari J., et al. Circulating bone marrow-derived endothelial progenitor cells: characterization, mobilization, and therapeutic considerations in malignant disease. Cytometry A 73 (2008) 186-193
20. Yoder M.C., Mead L.E., Prater D., et al. Redefining endothelial progenitor cells via clonal analysis and hematopoietic stem/progenitor cell principals. Blood 109 (2007) 1801-1809
21. Urbich C., and Dimmeler S. Endothelial progenitor cells: characterization and role in vascular biology. Circ Res 95 (2004) 343-353
22. Shantsila E., Watson T., and Lip G.Y. Endothelial progenitor cells in cardiovascular disorders. J Am Coll Cardiol 49 (2007) 741-752
23. Aicher A., Heeschen C., Mildner-Rihm C., et al. Essential role of endothelial nitric oxide synthase for mobilization of stem and progenitor cells. Nat Med 9 (2003) 1370-1376
24. Leone A.M., Rutella S., Bonanno G., et al. Mobilization of bone marrow-derived stem cells after myocardial infarction and left ventricular function. Eur Heart J 26 (2005) 1196-1204
25. Thum T., Fraccarollo D., Schultheiss M., Froese S., Galuppo P., Widder J.D., Tsikas D., Ertl G., and Bauersachs J. Endothelial nitric oxide synthase uncoupling impairs endothelial progenitor cell mobilization and function in diabetes. Diabetes 56 (2007) 666-674
26. Sarto P., Balducci E., Balconi G., et al. Effects of exercise training on endothelial progenitor cells in patients with chronic heart failure. J Card Fail 13 (2007) 701-708
27. Laufs U., Werner N., Link A., et al. Physical training increases endothelial progenitor cells, inhibits neointima formation, and enhances angiogenesis. Circulation 109 (2004) 220-226
28. Rehman J., Li J., Parvathaneni L., et al. Exercise acutely increases circulating endothelial progenitor cells and monocyte-/macrophage-derived angiogenic cells. J Am Coll Cardiol 43 (2004) 2314-2318