A novel mutated cell line with characteristics of dedifferentiated chondrosarcoma

International Journal of Molecular Medicine

Volumn 24, Issue 4, 2009, Pages 427-435

  Yang, Liye ^a,b   Chen, Qiang ^a,c   Zhang, Song ^a,b   Wang, Xianyao ^a,b   Li, Wenyu ^a,b   Wen, Jiancheng ^b   Huang, Xiaoping ^b   Zheng, Jiakun ^b   Huang, Ge ^a   Huang, Tianhua ^a   Ju, Guizhi ^c  

^a SHANTOU UNIVERSITY MEDICAL COLLEGE   (China)

^b Chaozhou Central Hospital Affiliated to Southern Medical University   (China)

^c JILIN UNIVERSITY   (China)

Author keywords

Chondrosarcoma; Dedifferentiated chondrosaroma; Fibrosarcoma; Malignant transformation; Muscle stem cell

Indexed keywords

ALCIAN BLUE; ALPHA ACTIN; COLLAGEN TYPE 2; DESMIN; PROTEIN P16; PROTEIN S 100; TOLONIUM CHLORIDE; VIMENTIN;

ADIPOCYTE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CELL CULTURE; CARCINOGENESIS; CELL DEDIFFERENTIATION; CELL GROWTH; CELL IMMORTALIZATION; CELL MUTANT; CHONDROSARCOMA; CHROMOSOME NUMBER; CONTROLLED STUDY; CYTOGENETICS; ELECTRON MICROSCOPY; EMBRYO; FIBROSARCOMA; GENE DELETION; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; KARYOTYPE; MALIGNANT TRANSFORMATION; MOUSE; MUSCLE CELL; NERVE CELL DIFFERENTIATION; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL;

ACTINS; ADIPOGENESIS; ANIMALS; CELL DIFFERENTIATION; CELL LINE, TUMOR; CHONDROSARCOMA; DESMIN; FEMALE; HUMANS; KARYOTYPING; MICE; MICE, NUDE; MICROSCOPY, ELECTRON, TRANSMISSION; MUTATION; POLYMERASE CHAIN REACTION; PREGNANCY; VIMENTIN;

EID: 70350752067     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm_00000249     Document Type: Article

References (29)

1. Berend KR, Toth AP, Harrelson JM, Layfield LJ, Hey LA and Scully SP: Association between ratio of matrix metalloproteinase-1 to tissue inhibitor of metalloproteinase-1 and local recurrence, metastasis, and survival in human chondrosarcoma. J Bone Joint Surg Am 80: 11-17, 1998.
2. Huvos AG: Chondrosarcoma including spindle-cell (dedifferentiated) and myxoid chondrosarcoma; mesenchymal chondrosarcoma. In: Bone Tumors. Huvos AG (ed). W.B. Saunders Company, Philadelphia, pp343-381, 1991.
3. Mirra JM and Marcove RC: Fibrosarcomatous dedifferentiation of primary and secondary chondrosarcoma. Review of five cases. J Bone Jt Surg Am 56: 285-296, 1974.
4. Unni KK: Chondrosarcoma. In: Dahlin's Bone Tumors. Unni KK (ed). Lippincott-Raven, Philadelphia, pp71-108, 1996.
5. Dahlin DC and Beabout JW: Dedifferentiation of low-grade chondrosarcomas. Cancer 28: 461-466, 1971.
6. Bruns J, Fiedler W, Werner M and Delling G: Dedifferentiated chondrosarcoma - a fatal disease. J Cancer Res Clin Oncol 131: 333-339, 2005.
7. Capanna R, Bertoni F, Bettelli G, Picci P, Bacchini P, Present D, Giunti A and Campanacci M: Dedifferentiated chondrosarcoma. J Bone Jt Surg Am 70: 60-69, 1988.
8. Staals EL, Bacchini P and Bertoni F: Dedifferentiated central chondrosarcoma. Cancer 106: 2682-2691, 2006.
9. Huvos AG: Chondrosarcoma including spindle-cell (dedifferentiated) and myxoid chondrosarcoma: mesenchymal chondrosarcoma. In: Bone Tumors: Diagnosis, Treatment, and Prognosis. Mitchell J (ed). 2nd Edition, W.B. Saunders Company, Philadelphia, pp343-393, 1991.
10. Frassica F, Unni K, Beabout J and Sim F: Dedifferentiated chondrosarcoma: a report of the clinicopathological features and treatment of seventy-eight cases. J Bone Joint Surg Am 68: 1197-1205, 1986.
11. Anract P, Tomeno B and Forest M: Dedifferentiated chondrosarcoma: a study of 13 clinical cases and review of the literature. Rev Chir Orthop Reparatrice Appar Mot 80: 669-680, 1994.
12. Mitchell AD, Ayoub K, Mangham DC, Grimer RJ, Carter SR and Tillman RM: Experience in the treatment of dedifferentiated chondrosarcoma. J Bone Joint Surg Br 82: 55-61, 2000.
13. Kudo N, Ogose A, Hotta T, Kawashima H, Gu W, Umezu H, Toyama T and Endo N: Establishment of novel human dedifferentiated chondrosarcoma cell line with osteoblastic differentiation. Virchows Arch 451: 691-699, 2007.
14. Seabright M: A rapid banding technique for human chromosomes. Lancet 2: 971-972, 1971.
15. Pittenger MF, Mackay AM, Beck SC, Jaiswal RK, Douglas R, Mosca JD, Moorman MA, Simonetti DW, Craig S and Marshak DR: Multilineage potential of adult human mesenchymal stem cells. Science 284: 143-147, 1999.
16. Yang LY, Huang TH and Ma L: Bone marrow stromal cells express neural phenotypes in vitro and migrate in brain after transplantation in vivo. Biomed Environ Sci 19: 329-335, 2006.
17. Kamb A, Gruis NA, Weaver-Feldhaus J, Liu Q, Harshman K, Tavtigian SV, Stockert E, Day RS 3rd, Johnson BE and Skolnick MH: A cell cycle regulator potentially involved in genesis of many tumor types. Science 264: 436-440, 1994.
18. Li HC, Stoicov C, Rogers AB and Houghton J: Stem cells and cancer: evidence for bone marrow stem cells in epithelial cancers. World J Gastroenterol 12: 363-371, 2006.
19. Bovee JV, Cleton-Jansen AM, Rosenberg C, Taminiau AH, Cornelisse CJ and Hogendoorn PC: Molecular genetic characterization of both components of a dedifferentiated chondrosarcoma, with implications for its histogenesis. J Pathol 189: 454-462, 1999.
20. Grote HJ, Schneider-Stock R, Neumann W and Roessner A: Mutation of p53 with loss of heterozygosity in the osteo-sarcomatous component of a dedifferentiated chondrosarcoma. Virchows Arch 436: 494-497, 2000.
21. Nawa G, Ueda T, Mori S, Yoshikawa H, Fukuda H, Ishiguro S, Funai H and Uchida A: Prognostic significance of Ki67 (MIB1) proliferation index and p53 over-expression in chondrosarcomas. Int J Cancer 69: 86-91, 1996.
22. Oshiro Y, Chaturvedi V, Hayden D, Nazeer T, Johnson M, Johnston DA, Ordonez NG, Ayala AG and Czerniak B: Altered p53 is associated with aggressive behavior of chondrosarcoma: a long term follow-up study. Cancer 83: 2324-2234, 1998.
23. Simms WW, Ordonez NG, Johnston D, Ayala AG and Czerniak B: p53 expression in dedifferentiated chondrosarcoma. Cancer 76: 223-227, 1995.
24. Campanacci M, Bertoni F and Capanna R: Dedifferentiated chondrosarcomas. Ital J Orthop Traumatol 5: 331-341, 1979.
25. Daly PJ, Sim FH and Wold LE: Dedifferentiated chondrosarcoma of bone. Orthopedics 12: 763-767, 1989.
26. Mercuri M, Picci P, Campanacci L and Rulli E: Dedifferentiated chondrosarcoma. Skeletal Radiol 24: 409-416, 1995.
27. Kudawara I, Araki N, Myoui A, Kato Y, Uchida A and Yoshikawa H: New cell lines with chondrocytic phenotypes from human chondrosarcoma. Virchows Arch 444: 577-586, 2004.
28. Kunisada T, Miyazaki M, Mihara K, Gao C, Kawai A, Inoue H and Namba M: A new human chondrosarcoma cell line (OUMS-27) that maintains chondrocytic differentiation. Int J Cancer 77: 854-859, 1998.
29. Yagami K, Uyama Y, Yoshizawa Y, Kakuta S, Yamaguchi A and Nagumo M: A human chondrogenic cell line retains multipotency that differentiates into osteoblasts and adipocytes. Bone 34: 648-655, 2004.