A novel injectable hydrogel in combination with a surgical sealant in a rat knee osteochondral defect model

Knee Surgery, Sports Traumatology, Arthroscopy

Volumn 17, Issue 11, 2009, Pages 1326-1331

  Miljkovic, Natasa D ^a   Lin, Yen Chih ^a   Cherubino, Mario ^a   Minteer, Danielle ^b   Marra, Kacey G ^a,b,c,d  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b University of Pittsburgh   (United States)

^c UNIVERSITY OF PITTSBURGH   (United States)

^d UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

Author keywords

Hydrogel; Osteochondral defect; Surgical sealant

Indexed keywords

BIOMATERIAL; TISSUE ADHESIVE;

ANIMAL; ARTICLE; ARTICULAR CARTILAGE; CHONDROPATHY; DISEASE MODEL; FEMALE; HYDROGEL; INJURY; INTRAARTICULAR DRUG ADMINISTRATION; KNEE; KNEE INJURY; RAT;

ANIMALS; BIOCOMPATIBLE MATERIALS; CARTILAGE DISEASES; CARTILAGE, ARTICULAR; DISEASE MODELS, ANIMAL; FEMALE; HYDROGEL; INJECTIONS, INTRA-ARTICULAR; KNEE INJURIES; KNEE JOINT; RATS; TISSUE ADHESIVES;

EID: 70350724693     PISSN: 09422056     EISSN: 14337347     Source Type: Journal    
DOI: 10.1007/s00167-009-0881-2     Document Type: Article

References (39)

1. Aaron R, Ciombor D, Wang S, Simon B (2006) Clinical biophysics: the promotion of skeletal repair by physical forces. Ann N Y Acad Sci 1068:513-531.
2. Arthritis: Centers for Disease Control and Prevention. Available at: http://www.cdc.gov.
3. Bryant S, Anseth K, Lee D, Bader D (2004) Crosslinking density influences the morphology of chondrocytes photoencapsulated in PEG hydrogels during the application of compressive strain. J Orthop Res 22:1143-1149.
4. Bryant S, Arthur J, Anseth K (2005) Incorporation of tissue-specific molecules alters chondrocyte metabolism and gene expression in photocrosslinked hydrogels. Acta Biomater 1:243-252.
5. Bryant S, Durand K, Anseth K (2003) Manipulations in hydrogel chemistry control photoencapsulated chondrocyte behavior and their extracellular matrix production. J Biomed Mater Res A 67:1430-1460.
6. Charlton D, Peterson M, Spiller K, Lowman A et al (2008) Semi-degradable scaffold for articular cartilage replacement. Tissue Eng Part A 14:207-213.
7. Cole J, Bondurant C (1964) Late thrombosis following the use of autogenous fascia and a cyanoacrylate (Eastman 910 monomer) for the wrapping of an intracranial aneurysm. J Neurosurg 21:884-886.
8. Dickhut A, Gottwald E, Steck E, Heisel C et al (2008) Chondrogenesis of mesenchymal stem cells in gel-like biomaterials in vitro and in vivo. Front Biosci 13:4517-4528.
9. Ferretti M, Marra KG, Kobayashi K, Defail AJ et al (2006) Controlled in vivo degradation of genipin crosslinked polyethylene glycol hydrogels within osteochondral defects. Tissue Eng 12(9):2657-2663.
10. Holland T, Bodde E, Baggett L, Tabata Y et al (2005) Osteochondral repair in the rabbit model utilizing bilayered, degradable oligo(poly(ethylene glycol)fumarate) hydrogel scaffolds. J Biomed Mater Res A 75:156-167.
11. Holland T, Tessmar J, Tabata Y, Mikos A (2004) Transforming growth factor-beta 1 release from oligo(poly(ethylene glycol) fumarate) hydrogels in conditions that model the cartilage wound healing environment. J Control Release 94:101-114.
12. Ishii I, Mizuta H, Sei A, Hirose J et al (2007) Healing of full-thickness defects of the articular cartilage in rabbits using fibroblast growth factor-2 and a fibrin sealant. J Bone Joint Surg Br 89:693-700.
13. Ishida K, Kuroda R, Miwa M, Tabata Y et al (2007) The regenerative effects of platelet-rich plasma on meniscal cells in vitro and its in vivo application with biodegradable gelatin hydrogel. Tissue Eng 13:1103-1112.
14. Issa J, Bentley M, Iyomasa M, Sebald W et al (2008) Sustained release carriers used to delivery bone morphogenetic proteins in the bone healing process. Anat Histol Embryol 37:181-187.
15. Ito Y, Ochi M, Adachi N, Sugawara K et al (2005) Repair of osteochondral defect with tissue-engineered chondral plug in a rabbit model. Arthroscopy 21:1155-1163.
16. Kim J, Lee K, Hefferan T, Currier B et al (2008) Synthesis and evaluation of novel biodegradable hydrogels based on poly(ethylene glycol) and sebacic acid as tissue engineering scaffolds. Biomacromolecules 9:149-157.
17. Koo H, Song Y, Kim H, Lee Y et al (2004) Anti-inflammatory effects of genipin, an active principle of gardenia. Eur J Pharmacol 495:201-208.
18. Kushibiki T, Matsuoka H, Tabata Y (2004) Synthesis and physical characterization of poly(ethylene glycol)-gelatin conjugates. Biomacromolecules 5:202-208.
19. Lenaerts V, Couvreur P, Christiaens-Leyh D, Joiris E et al (1984) Degradation of poly (isobutyl cyanoacrylate) nanoparticles. Biomaterials 5:65-68.
20. Liu Y, Shu X, Prestwich G (2006) Osteochondral defect repair with autologous bone marrow-derived mesenchymal stem cells in an injectable, in situ, cross-linked synthetic extracellular matrix. Tissue Eng 12:3405-3416.
21. Lu L, Zhu X, Valenzuela R, Currier B et al (2001) Biodegradable polymer scaffolds for cartilage tissue engineering. Clin Orthop Relat Res 391(Suppl):S251-S270.
22. Martens P, Bryant S, Anseth K (2003) Tailoring the degradation of hydrogels formed from multivinyl poly(ethylene glycol) and poly(vinyl alcohol) macromers for cartilage tissue engineering. Biomacromolecules 4:283-292.
23. Moffat L, Marra K (2004) Biodegradable poly(ethylene glycol) hydrogels crosslinked with genipin for tissue engineering applications. J Biomed Mater Res B Appl Biomater 71:181-187.
24. Nakayama J, Fujioka H, Nagura I, Kokubu T et al (2009) The effect of fibroblast growth factor-2 on autologous osteochondral transplantation. Int Orthop 33(1):275-280.
25. Nishida T, Kubota S, Kojima S, Kuboki T et al (2004) Regeneration of defects in articular cartilage in rat knee joints by CCN2 (connective tissue growth factor). J Bone Miner Res 19:1308-1319.
26. Papatheofanis F (1989) Surgical repair of rabbit tibia osteotomy using isobutyl-2-cyanoacrylate. Arch Orthop Trauma Surg 108:236-237.
27. Park Y, Lutolf M, Hubbell J, Hunziker E et al (2004) Bovine primary chondrocyte culture in synthetic matrix metalloproteinase-sensitive poly(ethylene glycol)-based hydrogels as a scaffold for cartilage repair. Tissue Eng 10:515-522.
28. Passl R, Plenk HJ (1989) Fibrin adhesion of cartilage surfaces. Beitr Orthop Traumatol 36:503-507.
29. Pérez M, Fernández I, Márquez D, Bretaña R (2000) Use of N-butyl-2-cyanoacrylate in oral surgery: biological and clinical evaluation. Artif Organs 24:241-243.
30. Schagemann JC, Erggelet C, Chung HW, Lahm A et al (2009) Cell-laden and cell-free biopolymer hydrogel for the treatment of osteochondral defects in a sheep model. Tissue Eng Part 15(1):75-82.
31. Schulz R, Bader A (2007) Cartilage tissue engineering and bioreactor systems for the cultivation and stimulation of chondrocytes. Eur Biophys J 36:539-568.
32. Setlik D, Seldomridge D, Adelman R, Semchyshyn T et al (2005) The effectiveness of isobutyl cyanoacrylate tissue adhesive for the treatment of corneal perforations. Am J Ophthalmol 140:920-921.
33. Sun G, Zhang X, Chu C (2008) Effect of the molecular weight of polyethylene glycol (PEG) on the properties of chitosan-PEG-poly(N-isopropylacrylamide) hydrogels. J Mater Sci: Mater Med 19:2865-2872.
34. Tam H, Srivastava A, Colwell CJ, D'Lima D (2007) In vitro model of full-thickness cartilage defect healing. J Orthop Res 25:1136-1144.
35. Toriumi D, Raslan W, Friedman M, Tardy M (1990) Histotoxicity of cyanoacrylate tissue adhesives. A comparative study. Arch Otolaryngol Head Neck Surg 116:546-550.
36. Toriumi D, Raslan W, Friedman M, Tardy MJ (1991) Variable histotoxicity of histoacryl when used in a subcutaneous site: an experimental study. Laryngoscope 101:339-343.
37. Varghese S, Hwang N, Canver A, Theprungsirikul P et al (2008) Chondroitin sulfate based niches for chondrogenic differentiation of mesenchymal stem cells. Matrix Biol 27:12-21.
38. Wilson D, Chenery D, Bowring H, Wilson K et al (2005) Physical and biological properties of a novel siloxane adhesive for soft tissue applications. J Biomater Sci Polym Ed 16:449-472.
39. Xian C, Foster B (2006) Repair of injured articular and growth plate cartilage using mesenchymal stem cells and chondrogenic gene therapy. Curr Stem Cell Res Ther 1:213-229.