메뉴 건너뛰기




Volumn 61, Issue 8, 2009, Pages 846-852

Over-expression of pemt2 into rat hepatoma cells contributes to the mitochondrial apoptotic pathway

Author keywords

Apoptosis; Caspase; Cytochrome C; Mitochondria; Phosphatidylcholine (PC); Phosphatidylethanolamine (PE); Phosphatidylethanolamine N methyltransferase 2 (PEMT2)

Indexed keywords

CASPASE 3; CASPASE 9; CYTOCHROME C; PHOSPHATIDYLETHANOLAMINE METHYLTRANSFERASE; PHOSPHATIDYLETHANOLAMINE METHYLTRANSFERASE 2; UNCLASSIFIED DRUG; PHOSPHATIDYLCHOLINE;

EID: 70350717096     PISSN: 15216543     EISSN: 15216551     Source Type: Journal    
DOI: 10.1002/iub.222     Document Type: Article
Times cited : (3)

References (33)
  • 1
    • 0031553042 scopus 로고    scopus 로고
    • CTP: Phosphocholine cytidylyltransferase
    • Kent, C. (1997) CTP: phosphocholine cytidylyltransferase. Biochim. Biophys. Acta. 1348, 79-90.
    • (1997) Biochim. Biophys. Acta , vol.1348 , pp. 79-90
    • Kent, C.1
  • 2
    • 0027182769 scopus 로고
    • Cloning and expression of a novel phosphatidylethanolamine N-methyltransferase. A specific biochemical and cytological marker for a unique membrane fraction in rat liver
    • Cui, Z., Vance, J. E., Chen, M. H., Voelker, D. R., and Vance, D. E. (1993) Cloning and expression of a novel phosphatidylethanolamine N-methyltransferase. A specific biochemical and cytological marker for a unique membrane fraction in rat liver. J. Biol. Chem. 268, 16655-16663.
    • (1993) J. Biol. Chem. , vol.268 , pp. 16655-16663
    • Cui, Z.1    Vance, J.E.2    Chen, M.H.3    Voelker, D.R.4    Vance, D.E.5
  • 3
    • 0031576039 scopus 로고    scopus 로고
    • Inverse correlation between expression of phosphatidylethano-lamine N-methyltransferase-2 and growth rate of perinatal rat livers
    • Cui, Z., Shen, Y. J., and Vance, D. E. (1997) Inverse correlation between expression of phosphatidylethano-lamine N-methyltransferase-2 and growth rate of perinatal rat livers. Biochim. Biophys. Acta. 1346, 10-16.
    • (1997) Biochim. Biophys. Acta , vol.1346 , pp. 10-16
    • Cui, Z.1    Shen, Y.J.2    Vance, D.E.3
  • 4
    • 0031576034 scopus 로고    scopus 로고
    • Induction of hepatocyte proliferation after partial hepatectomy is accompanied by a markedly reduced expression of phosphatidylethanolamine N-methyltransferase 2
    • Honweling, M., Cui, Z., Tessitore, L., and Vance, D. E. 1997. Induction of hepatocyte proliferation after partial hepatectomy is accompanied by a markedly reduced expression of phosphatidylethanolamine N-methyltransferase 2. Biochim. Biophys. Acta. 1348, 1-9.
    • (1997) Biochim. Biophys. Acta , vol.1348 , pp. 1-9
    • Honweling, M.1    Cui, Z.2    Tessitore, L.3    Vance, D.E.4
  • 5
    • 0032960152 scopus 로고    scopus 로고
    • Diminished expression of phosphatidylethanolamine N-methyltransferase 2 during hepatocarcinogenesis
    • DOI 10.1042/0264-6021:3370023
    • Tessitore, L., Dianzani, I., Cui, Z., and Vance, D. E. (1999) Diminished expression of phosphatidylethanolamine N-methyltransferase 2 during hepatocarcinogenesis. Biochem. J. 337, 23-27. (Pubitemid 29039078)
    • (1999) Biochemical Journal , vol.337 , Issue.1 , pp. 23-27
    • Tessitore, L.1    Dianzani, I.2    Cui, Z.3    Vance, D.E.4
  • 6
    • 0037088228 scopus 로고    scopus 로고
    • Over-expression of PEMT2 downregulates the PI3K/Akt signaling pathway in rat hepatoma cells
    • Zou, W., Li, Z. Y., Li, Y. L., Ma, K. L., and Tsui, Z. C. (2002) Over-expression of PEMT2 downregulates the PI3K/Akt signaling pathway in rat hepatoma cells. Biochim. Biophys. Acta. 1581, 49-56.
    • (2002) Biochim. Biophys. Acta , vol.1581 , pp. 49-56
    • Zou, W.1    Li, Z.Y.2    Li, Y.L.3    Ma, K.L.4    Tsui, Z.C.5
  • 7
    • 0033065055 scopus 로고    scopus 로고
    • Expression of phosphatidylethanolamine N-methyltransferase in Yoshida ascites hepatoma cells and the livers of host rats
    • Tessitore, L., Sesca, E., Bosco, M., and Vance, D. E. (1999) Expression of phosphatidylethanolamine N-methyltransferase in Yoshida ascites hepatoma cells and the livers of host rats. Carcinogenesis 20, 561-567.
    • (1999) Carcinogenesis , vol.20 , pp. 561-567
    • Tessitore, L.1    Sesca, E.2    Bosco, M.3    Vance, D.E.4
  • 8
    • 2442418909 scopus 로고    scopus 로고
    • Transfection of pemt2-cDNA inhibits c-Met and Bcl-2 expression and induces apoptosis in rat CBRH-7919 hepatoma cells
    • Zou, W., Li, Z. Y., Li, Y. L., Ma, K. L., Xia, Q., and Tsui, Z. C. (2001) Transfection of pemt2-cDNA inhibits c-Met and Bcl-2 expression and induces apoptosis in rat CBRH-7919 hepatoma cells. Chinese J. Biochem. Mol. Biol. 17, 661-665.
    • (2001) Chinese J. Biochem. Mol. Biol. , vol.17 , pp. 661-665
    • Zou, W.1    Li, Z.Y.2    Li, Y.L.3    Ma, K.L.4    Xia, Q.5    Tsui, Z.C.6
  • 9
    • 0033569752 scopus 로고    scopus 로고
    • Molecular distinction of phosphatidylcholine synthesis between the CDP-choline pathway and phosphatidylethanolamine methylation pathway
    • Delong, C. J., Shen, Y. J., Thomas, M. J., and Cui, Z. (1999) Molecular distinction of phosphatidylcholine synthesis between the CDP-choline pathway and phosphatidylethanolamine methylation pathway. J. Biol. Chem. 274, 29683-29688.
    • (1999) J. Biol. Chem. , vol.274 , pp. 29683-29688
    • Delong, C.J.1    Shen, Y.J.2    Thomas, M.J.3    Cui, Z.4
  • 10
    • 0346034955 scopus 로고    scopus 로고
    • The two biosynthetic routes leading to phosphatidylcholine in yeast produce different sets of molecular species. Evidence for lipid remodeling
    • Boumann, H. A., Damen, M. J., Versluis, C., Heck, A. J., Kruijffde, B. D., and Kroon, A. I. (2003) The two biosynthetic routes leading to phosphatidylcholine in yeast produce different sets of molecular species. Evidence for lipid remodeling. Biochemistry 42, 3054-3059.
    • (2003) Biochemistry , vol.42 , pp. 3054-3059
    • Boumann, H.A.1    Damen, M.J.2    Versluis, C.3    Heck, A.J.4    Kruijffde, B.D.5    Kroon, A.I.6
  • 11
    • 7444256744 scopus 로고    scopus 로고
    • Contribution of different biosynthetic pathways to species selectivity of aminoglycerophospholipids assembled into mitochondrial membranes of the yeast Saccharomyces cerevisiae
    • Bürgermeister, M., Birner-Grünberger, R., Heyn, M., Daum, G. (2004) Contribution of different biosynthetic pathways to species selectivity of aminoglycerophospholipids assembled into mitochondrial membranes of the yeast Saccharomyces cerevisiae. Biochim. Biophys. Acta. 1686, 148-160.
    • (2004) Biochim. Biophys. Acta , vol.1686 , pp. 148-160
    • Bürgermeister, M.1    Birner-Grünberger, R.2    Heyn, M.3    Daum, G.4
  • 12
    • 0035896516 scopus 로고    scopus 로고
    • Highly saturated endonuclear phosphatidylcholine is synthesized in situ and colocated with CDP-choline pathway enzymes
    • Hunt, A. N., Clark, G. T., Attard, G. S., and Postle, A. D. (2001) Highly saturated endonuclear phosphatidylcholine is synthesized in situ and colocated with CDP-choline pathway enzymes. J. Biol. Chem. 276, 8492-8499.
    • (2001) J. Biol. Chem. , vol.276 , pp. 8492-8499
    • Hunt, A.N.1    Clark, G.T.2    Attard, G.S.3    Postle, A.D.4
  • 13
    • 7444237160 scopus 로고    scopus 로고
    • Contribution of different pathways to the supply of phosphatidylethanolamine and phosphatidylcholine to mitochondrial membranes of the yeast Saccharomyces cerevisiae
    • Bürgermeister, M., Birner-Grünberger, R., Nebauer, R., and Daum, G. (2004) Contribution of different pathways to the supply of phosphatidylethanolamine and phosphatidylcholine to mitochondrial membranes of the yeast Saccharomyces cerevisiae. Biochim. Biophys. Acta. 1686, 161-168.
    • (2004) Biochim. Biophys. Acta , vol.1686 , pp. 161-168
    • Bürgermeister, M.1    Birner-Grünberger, R.2    Nebauer, R.3    Daum, G.4
  • 14
    • 0033569752 scopus 로고    scopus 로고
    • Molecular distinction of phosphatidylcholine synthesis between the CDP-choline pathway and phosphatidylethanolamine methylation pathway
    • DeLong, C. J., Shen, Y. J., Thomas, M. J., and Cui, Z. (1999) Molecular distinction of phosphatidylcholine synthesis between the CDP-choline pathway and phosphatidylethanolamine methylation pathway. J. Biol. Chem. 274, 29683-29688.
    • (1999) J. Biol. Chem. , vol.274 , pp. 29683-29688
    • DeLong, C.J.1    Shen, Y.J.2    Thomas, M.J.3    Cui, Z.4
  • 15
    • 0008838054 scopus 로고    scopus 로고
    • Construction of pLNCX-pemt2 vector and expression of pemt2 gene in rat hepatoma CBRH-7919 cells
    • Zou, W., Li, C. L., Li, Z. Y., Li, Y. L., Ma, K. L., Xia, Q., and Tsui, Z. C. (2000) Construction of pLNCX-pemt2 vector and expression of pemt2 gene in rat hepatoma CBRH-7919 cells. Chinese J. Biochem. Mol. Biol. 16, 597-601.
    • (2000) Chinese J. Biochem. Mol. Biol. , vol.16 , pp. 597-601
    • Zou, W.1    Li, C.L.2    Li, Z.Y.3    Li, Y.L.4    Ma, K.L.5    Xia, Q.6    Tsui, Z.C.7
  • 16
    • 0016391512 scopus 로고
    • Preparation of methylesters from the saponifiable fatty acids in small biological specimens for gas-liquid chromatographic analysis
    • MacGee, J. and Allen, G. (1974) Preparation of methylesters from the saponifiable fatty acids in small biological specimens for gas-liquid chromatographic analysis. J. Chromatogr. 100, 35-42.
    • (1974) J. Chromatogr. , vol.100 , pp. 35-42
    • MacGee, J.1    Allen, G.2
  • 17
    • 0019316059 scopus 로고
    • Subcellular fractionation of isolated rat hepatocytes: A comparison with liver homogenate
    • Krack, G., Gravier, O., Roberfroi. M. D., and Mercier, M. (1980) Subcellular fractionation of isolated rat hepatocytes: a comparison with liver homogenate. Biochim. Biophys. Acta. 632, 619-629.
    • (1980) Biochim. Biophys. Acta , vol.632 , pp. 619-629
    • Krack, G.1    Gravier, O.2    Roberfroi, M.D.3    Mercier, M.4
  • 18
    • 0029155942 scopus 로고
    • A comparison of the fluorescence properties of TMA-DPH as a probe for plasma membrane and for endocytic membrane
    • Illinger, D., Duportail, G., Mely, Y., Poirel-Morales, N., Gerard, D., and Kuhry, J. G. (1995) A comparison of the fluorescence properties of TMA-DPH as a probe for plasma membrane and for endocytic membrane. Biochim. Biophys. Acta. 1239, 58-66.
    • (1995) Biochim. Biophys. Acta , vol.1239 , pp. 58-66
    • Illinger, D.1    Duportail, G.2    Mely, Y.3    Poirel-Morales, N.4    Gerard, D.5    Kuhry, J.G.6
  • 19
    • 0033869801 scopus 로고    scopus 로고
    • Preferential distribution of long chain polyunsaturated fatty acids in phosphatidylethano- Lamine fraction of guinea pig alveolar apical membranes
    • Mukhopadhyay, S., Muimo, R., Campbell, F. M., Gordon, M. J., Monaghan, A. S., and Dutta-Roy, A. K. (2000) Preferential distribution of long chain polyunsaturated fatty acids in phosphatidylethano- lamine fraction of guinea pig alveolar apical membranes. Prostaglandins Leukot. Essent. Fatty Acids 62, 341-348.
    • (2000) Prostaglandins Leukot. Essent. Fatty Acids , vol.62 , pp. 341-348
    • Mukhopadhyay, S.1    Muimo, R.2    Campbell, F.M.3    Gordon, M.J.4    Monaghan, A.S.5    Dutta-Roy, A.K.6
  • 20
    • 4644358597 scopus 로고    scopus 로고
    • The yeast phospholipid N-methyltransferases catalyzing the synthesis of phosphatidylcholine preferentially convert di- C16:1 substrates both in vivo and in vitro
    • Boumann, H. A., Chin, P. T., Heck, A. J., Kruijff, B. D., and De Kroon, A. I. (2004) The yeast phospholipid N-methyltransferases catalyzing the synthesis of phosphatidylcholine preferentially convert di- C16:1 substrates both in vivo and in vitro. J. Biol. Chem. 279, 40314-40319.
    • (2004) J. Biol. Chem. , vol.279 , pp. 40314-40319
    • Boumann, H.A.1    Chin, P.T.2    Heck, A.J.3    Kruijff, B.D.4    De Kroon, A.I.5
  • 21
    • 0023779362 scopus 로고
    • Specificity of rat hepatic hosphatidyletholamine N-methyltransferase for molecular species of diacyl phosphatidylethanolamine
    • Ridgway, N. D. and Vance, D. E. (1988) Specificity of rat hepatic hosphatidyletholamine N-methyltransferase for molecular species of diacyl phosphatidylethanolamine. J. Biol. Chem. 263, 16856-16863.
    • (1988) J. Biol. Chem. , vol.263 , pp. 16856-16863
    • Ridgway, N.D.1    Vance, D.E.2
  • 24
    • 34247506768 scopus 로고    scopus 로고
    • A tale of two mitochondrial channels, MAC and PTP, in apoptosis
    • Kinnally, K. W. and Antonsson, B. (2007) A tale of two mitochondrial channels, MAC and PTP, in apoptosis. Apoptosis 12, 857-868.
    • (2007) Apoptosis , vol.12 , pp. 857-868
    • Kinnally, K.W.1    Antonsson, B.2
  • 25
    • 26444524046 scopus 로고    scopus 로고
    • The role of the mitochondrial apoptosis induced channel MAC in cytochrome c release
    • Martinez-Caballero, S., Dejean, L. M., Jonas, E. A., Kinnally, and K. W. (2005) The role of the mitochondrial apoptosis induced channel MAC in cytochrome c release. J. Bioenerg. Biomembr. 37, 155-164.
    • (2005) J. Bioenerg. Biomembr. , vol.37 , pp. 155-164
    • Martinez-Caballero, S.1    Dejean, L.M.2    Jonas, E.A.3    Kinnally, K.W.4
  • 26
    • 34247540380 scopus 로고    scopus 로고
    • The permeability transition pore in cell death
    • Grimm, S. and Brdiczka, D. (2007) The permeability transition pore in cell death. Apoptosis 12, 841-855.
    • (2007) Apoptosis , vol.12 , pp. 841-855
    • Grimm, S.1    Brdiczka, D.2
  • 28
    • 33745591102 scopus 로고    scopus 로고
    • Multiple pathways of cytochrome c release from mitochondria in apoptosis
    • Gogvadze, V., Orrenius, S., and Zhivotovsky, B. (2000) Multiple pathways of cytochrome c release from mitochondria in apoptosis. Biochim. Biophys. Acta. 1757(5/6), 639-647.
    • (2000) Biochim. Biophys. Acta. , vol.1757 , Issue.5-6 , pp. 639-647
    • Gogvadze, V.1    Orrenius, S.2    Zhivotovsky, B.3
  • 29
    • 0037347309 scopus 로고    scopus 로고
    • Chenodeoxycholate induction of mitochondrial permeability transition pore is associated with increased membrane fluidity and cytochrome c release: Protective role of carvedilol
    • Rolo, A. P., Oliveira, P. J., Moreno, A. J., and Palmeira, C. M. (2003) Chenodeoxycholate induction of mitochondrial permeability transition pore is associated with increased membrane fluidity and cytochrome c release: protective role of carvedilol. Mitochondrion 2, 305-311.
    • (2003) Mitochondrion , vol.2 , pp. 305-311
    • Rolo, A.P.1    Oliveira, P.J.2    Moreno, A.J.3    Palmeira, C.M.4
  • 30
    • 22544450163 scopus 로고    scopus 로고
    • Agaric acid induces mitochondrial permeability transition through its interaction with the adenine nucleotide translocase. Its dependence on membrane fluidity
    • García, N., Zazueta, C., Pavón, N., and Chávez, E. (2005) Agaric acid induces mitochondrial permeability transition through its interaction with the adenine nucleotide translocase. Its dependence on membrane fluidity. Mitochondrion 5, 272-281.
    • (2005) Mitochondrion , vol.5 , pp. 272-281
    • García, N.1    Zazueta, C.2    Pavón, N.3    Chávez, E.4
  • 31
    • 0141483378 scopus 로고    scopus 로고
    • Cholesterol impairs the adenine nucleotide translocator-mediated mitochondrial permeability transition through altered membrane fluidity
    • Colell, A., García-Ruiz, C., Lluis, J. M., Coll, O., Mari, M., and Fernández-Checa, J. C. (2003) Cholesterol impairs the adenine nucleotide translocator-mediated mitochondrial permeability transition through altered membrane fluidity. J. Biol. Chem. 278, 33928-33935.
    • (2003) J. Biol. Chem. , vol.278 , pp. 33928-33935
    • Colell, A.1    García-Ruiz, C.2    Lluis, J.M.3    Coll, O.4    Mari, M.5    Fernández-Checa, J.C.6
  • 32
    • 0345369287 scopus 로고    scopus 로고
    • Carboxyatractyloside increases the effect of oleate on mitochondrial permeability transition
    • Chávez, E., Zazueta, C., and García, N. (1999) Carboxyatractyloside increases the effect of oleate on mitochondrial permeability transition. FEBS Lett 445, 189-191.
    • (1999) FEBS Lett , vol.445 , pp. 189-191
    • Chávez, E.1    Zazueta, C.2    García, N.3
  • 33
    • 0034602536 scopus 로고    scopus 로고
    • Long-chain fatty acids promote opening of the reconstituted mitochondrial permeability transition pore
    • Wieckowski, M. R., Brdiczka, D., and Wojtczak, L. (2000) Long-chain fatty acids promote opening of the reconstituted mitochondrial permeability transition pore. FEBS Lett. 484, 61-64.
    • (2000) FEBS Lett. , vol.484 , pp. 61-64
    • Wieckowski, M.R.1    Brdiczka, D.2    Wojtczak, L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.