Elovl4 5-bp deletion knock-in mouse model for Stargardt-like macular degeneration demonstrates accumulation of ELOVL4 and lipofuscin

Experimental Eye Research

Volumn 89, Issue 6, 2009, Pages 905-912

  Vasireddy, Vidyullatha ^a   Jablonski, Monica M ^b   Khan, Naheed W ^c   Wang, Xiao Fei ^b   Sahu, Priya ^b   Sparrow, Janet R ^d   Ayyagari, Radha ^a  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^c UNIVERSITY OF MICHIGAN   (United States)

^d Columbia University ^*  (United States)

Author keywords

ELOVL4; lipofuscin; protein accumulation; STGD3

Indexed keywords

ELONGATION OF VERY LONG FATTY ACIDS 4 PROTEIN; LIPOFUSCIN; PROTEIN ELOVL4; UBIQUITIN; UNCLASSIFIED DRUG;

AGE DETERMINATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GENE DELETION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HISTOPATHOLOGY; IMMUNOFLUORESCENCE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; QUANTITATIVE ANALYSIS; RETINA INNER PLEXIFORM LAYER; STARGARDT DISEASE; WILD TYPE;

ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DISEASE MODELS, ANIMAL; EYE PROTEINS; GENE KNOCK-IN TECHNIQUES; LIPOFUSCIN; MACULAR DEGENERATION; MEMBRANE PROTEINS; MICE; MICE, MUTANT STRAINS; RETINA; RETINAL PIGMENT EPITHELIUM; UBIQUITIN;

EID: 70350704682     PISSN: 00144835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exer.2009.07.021     Document Type: Article

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