Selected polysaccharides at comparison for their mucoadhesiveness and effect on precorneal residence of different drugs in the rabbit model

Drug Development and Industrial Pharmacy

Volumn 35, Issue 8, 2009, Pages 941-949

  Di Colo, Giacomo ^a   Zambito, Ylenia ^a   Zaino, Chiara ^a   Sans, Marco ^b  

^a UNIVERSITY OF PISA   (Italy)

^b Farmigea SpA   (Italy)

Author keywords

Corneal contact time; Diclofenac; Eyedrops; Ketotifen; Mucoadhesive polysaccharide; Precorneal residence

Indexed keywords

ARABINOGALACTAN; DICLOFENAC; FIBERAID; HYALURONIC ACID; HYDROXYETHYLCELLULOSE; KETOFTIL; KETOTIFEN FUMARATE; MUCIN; POLYSACCHARIDE; UNCLASSIFIED DRUG;

ADHESION; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; CORNEA; DRUG FORMULATION; EXPERIMENTAL RABBIT; LACRIMAL FLUID; MALE; NONHUMAN; TAMARIND; VISCOSITY;

ADHESIVENESS; ANIMALS; ANTI-ALLERGIC AGENTS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CORNEA; DICLOFENAC; KETOTIFEN; MALE; OPHTHALMIC SOLUTIONS; POLYSACCHARIDES; RABBITS; SEEDS; TAMARINDUS; TEARS; TIME FACTORS; VISCOSITY;

EID: 70350690684     PISSN: 03639045     EISSN: 15205762     Source Type: Journal    
DOI: 10.1080/03639040802713460     Document Type: Article

References (23)

1. Chrai SS, Robinson JR. (1974). Ocular evaluation of methylcellulose vehicle in albino rabbits. J Pharm Sci, 63:1218-1223
2. Lee VHL, Robinson JR. (1986). Review: Topical ocular drug delivery: Recent developments and future challenges. J Ocul Pharmacol, 2:67-108.
3. Patton TF, Robinson JR. (1975). Ocular evaluation of polyvinylalcohol vehicle in rabbits. J Pharm Sci, 64:1312-1316
4. Saettone MF, Giannaccini B, Ravecca S, La Marca F, Tota G. (1984). Polymer effects on ocular bioavailability-the influence of different liquid vehicles on the mydriatic response of tropicamide in humans and rabbits. Int J Pharm, 20:187-202.
5. Saettone MF, Giannaccini B, Teneggi A, Savigni P, Tellini N. (1982). Vehicle effects on ophthalmic bioavailability: The influence of different polymers on the activity of pilocarpine in rabbit and man. J Pharm Pharmacol, 34:464-466
6. Trueblood JH, Rossomondo RM, Wilson LA, Carlton WH. (1975). Corneal contact times of ophthalmic vehicles. Evaluation by microscintigraphy. Arch Ophthalmol, 93:127-130
7. Hui H-W, Robinson JR. (1985). Ocular drug delivery of progesterone using a bioadhesive polymer. Int J Pharm, 26:203-213
8. Winfield AJ, Jessiman D, Williams A, Esakowitz L. (1990). A study of the causes of non-compliance by patients prescribed eyedrops. Br J Ophthalmol, 74:477-480
9. Burgalassi S, Nicosia N, Monti D, Falcone G, Boldrini E, Chetoni P. (2007). Larch arabinogalactan for dry eye protection and treatment of corneal lesions: Investigation in rabbits. J Ocul Pharmacol Ther, 23:541-549
10. Saettone MF, Burgalassi S, Boldrini P, Bianchini G. (1997). Ophthalmic solutions viscosified with tamarind seed polysaccharide. International patent application PCT/ IT97/00026, International Publication number WO 97/ 28787.
11. Gregory S, Kelly ND. (1999). Larch arabinogalactan: Clinical relevance of a novel immune-enhancing polysaccharide. Altern Med Rev, 4:96-103.
12. Lee JW, Park JH, Robinson JR. (2000). Bioadhesive-based dosage forms: The next generation. J Pharm Sci, 89:850-866
13. Mikos AG, Peppas NA. (1986). Systems for controlled release of drugs: V. Bioadhesive systems. S. T. P. Pharma Sci, 2:705-716
14. Hassan EE, Gallo JM. (1990). A simple rheological method for the in vitro assessment of mucin-polymer bioadhesive bond strength. Pharm Res, 7:491-495
15. Hägerström H, Edsman K. (2003). Limitations of the rheological mucoadhesion method: The effect of the choice of conditions and the rheological synergism parameter. Eur J Pharm Sci, 18:349-357
16. Bottari F, Di Colo G, Nannipieri E, Saettone MF, Serafini MF. (1975). Evaluation of a dynamic permeation technique for studying drug-macromolecule interaction. J Pharm Sci, 64:946-949
17. Greaves JL, Wilson CG. (1993). Treatment of diseases of the eye with mucoadhesive delivery systems. Adv Drug Deliv Rev, 11:349-383
18. Saettone MF, Giannaccini B, Barattini F, Tellini N. (1982). The validity of rabbits for investigations on ophthalmic vehicles: A comparison of four different vehicles containing tropicamide in humans and rabbits. Pharm Acta Helv, 57:47-55.
19. Zaki I, Fitzgerald P, Hardy JG, Wilson CG. (1986). A comparison of the effects of viscosity on the precorneal residence of solutions in rabbit and man. J Pharm Pharmacol, 38:463-466
20. Clausen AE, Bernkop-Schnürch A. (2000). In vitro evaluation of the permeation-enhancing effect of thiolated polycarbophil. J Pharm Sci, 89:1253-1261
21. Clausen AE, Bernkop-Schnürch A. (2001). Thiolated carboxymethylcellulose: In vitro evaluation of its permeation-enhancing effect on peptide drugs. Eur J Pharm Biopharm, 51:25-32.
22. Weast RC, ed. (1975). Handbook of chemistry and physics. 56th ed. Cleveland, (OH): CRC Press, F-49.
23. Uccello-Barretta G, Nazzi S, Balzano F, Di Colo G, Zambito Y, Zaino C, et al. (2008). Enhanced affinity of ketotifen toward tamarind seed polysaccharide in comparison with hydroxyethylcellulose and hyaluronic acid: A nuclear magnetic resonance investigation. Bioorg Med Chem, 16:7371-7376