메뉴 건너뛰기




Volumn 351, Issue 1-2, 2009, Pages 41-45

Neutralizing antibodies against IFN beta in patients with multiple sclerosis: A comparative study of two cytopathic effect tests (CPE) for their detection

Author keywords

A549 EMCV; Bioassay; Cytopathic effect method (CPE); HEP2 VSV; Interferon beta treatment; Neutralizing antibodies (NABs)

Indexed keywords

BETA1A INTERFERON; INTERFERON BETA SERINE; NEUTRALIZING ANTIBODY;

EID: 70350616193     PISSN: 00221759     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jim.2009.09.005     Document Type: Article
Times cited : (10)

References (25)
  • 1
    • 0036975338 scopus 로고    scopus 로고
    • A comparison of the biologic activity of two recombinant IFN-beta preparations used in the treatment of relapsing-remitting multiple sclerosis
    • Dec
    • Antonetti F., Finocchiaro O., Mascia M., Terlizzese M.G., and Jaber A. A comparison of the biologic activity of two recombinant IFN-beta preparations used in the treatment of relapsing-remitting multiple sclerosis. J. Interferon Cytokine Res. 22 12 (2002) 1181 Dec
    • (2002) J. Interferon Cytokine Res. , vol.22 , Issue.12 , pp. 1181
    • Antonetti, F.1    Finocchiaro, O.2    Mascia, M.3    Terlizzese, M.G.4    Jaber, A.5
  • 2
    • 0037465461 scopus 로고    scopus 로고
    • Persistent neutralizing antibodies abolish the interferon beta bioavailability in MS patients
    • Bertolotto F., and Gilli. Persistent neutralizing antibodies abolish the interferon beta bioavailability in MS patients. Neurology 60 (2003) 634
    • (2003) Neurology , vol.60 , pp. 634
    • Bertolotto, F.1    Gilli2
  • 3
    • 0036329631 scopus 로고    scopus 로고
    • Differential effects of three interferon betas on neutralising antibodies in patients with multiple sclerosis: A follow up study in an independent laboratory
    • Aug
    • Bertolotto, A., Malucchi, S., Sala, A., Orefice, G., Carrieri, P.B., Capobianco, M., Milano, E., Melis, F., Giordana, M.T., 2002. Differential effects of three interferon betas on neutralising antibodies in patients with multiple sclerosis: a follow up study in an independent laboratory. J. Neurol. Neurosurg. Psychiatry 73 (2),148 Aug.
    • (2002) J. Neurol. Neurosurg. Psychiatry , vol.73 , Issue.2 , pp. 148
    • Bertolotto, A.1    Malucchi, S.2    Sala, A.3    Orefice, G.4    Carrieri, P.B.5    Capobianco, M.6    Milano, E.7    Melis, F.8    Giordana, M.T.9
  • 5
    • 0030857343 scopus 로고    scopus 로고
    • The expression of potency of neutralizing antibodies for interferons and other cytokines
    • Grossberg S.E., and Kawade Y. The expression of potency of neutralizing antibodies for interferons and other cytokines. Biotherapy 10 1 (1997) 93
    • (1997) Biotherapy , vol.10 , Issue.1 , pp. 93
    • Grossberg, S.E.1    Kawade, Y.2
  • 6
    • 0034796419 scopus 로고    scopus 로고
    • The neutralization of interferons by antibody. II. Neutralizing antibody unitage and its relationship to bioassay sensitivity: the tenfold reduction unit
    • Sep
    • Grossberg S.E., Kawade Y., Kohase M., and Klein J.P. The neutralization of interferons by antibody. II. Neutralizing antibody unitage and its relationship to bioassay sensitivity: the tenfold reduction unit. J. Interferon Cytokine Res. 21 9 (2001) 743 Sep
    • (2001) J. Interferon Cytokine Res. , vol.21 , Issue.9 , pp. 743
    • Grossberg, S.E.1    Kawade, Y.2    Kohase, M.3    Klein, J.P.4
  • 7
    • 34547092660 scopus 로고    scopus 로고
    • Using measurements of neutralizing antibodies: The challenge of IFN-beta therapy
    • Review, Aug
    • Hesse, D., Sørensen, P.S., 2007. Using measurements of neutralizing antibodies: the challenge of IFN-beta therapy. Eur. J. Neurol. 14 (8), 850 Aug. Review.
    • (2007) Eur. J. Neurol , vol.14 , Issue.8 , pp. 850
    • Hesse, D.1    Sørensen, P.S.2
  • 8
    • 0142071149 scopus 로고    scopus 로고
    • Neutralization of the biological activity of cytokines and other protein effectors by antibody: theoretical formulation of antibody titration curves in relation to antibody affinity
    • Jul
    • Kawade Y., Finter N., and Grossberg S.E. Neutralization of the biological activity of cytokines and other protein effectors by antibody: theoretical formulation of antibody titration curves in relation to antibody affinity. J. Immunol. Methods 278 1-2 (2003) 127 Jul
    • (2003) J. Immunol. Methods , vol.278 , Issue.1-2 , pp. 127
    • Kawade, Y.1    Finter, N.2    Grossberg, S.E.3
  • 9
    • 33845395910 scopus 로고    scopus 로고
    • Massart, C., Gibassier, J., Oger, J., Le Page, E., Edan, G., 2007. Neutralizing antibodies to interferon beta in multiple sclerosis: analytical evaluation for validation of a cytopathic effect assay. Clin. Chim. Acta. 377 (1-2) 185-91 Feb. Electronic publication ahead of print 2006 Sep 30. Erratum in: Clin. Chim. Acta. 380 (1-2), 255 May.
    • Massart, C., Gibassier, J., Oger, J., Le Page, E., Edan, G., 2007. Neutralizing antibodies to interferon beta in multiple sclerosis: analytical evaluation for validation of a cytopathic effect assay. Clin. Chim. Acta. 377 (1-2) 185-91 Feb. Electronic publication ahead of print 2006 Sep 30. Erratum in: Clin. Chim. Acta. 380 (1-2), 255 May.
  • 10
    • 33644863225 scopus 로고    scopus 로고
    • Analysis of neutralizing antibodies to therapeutic interferon-beta in multiple sclerosis patients: a comparison of three methods in a large Australasian cohort
    • Mar 20, Dec 20
    • McKay F., Schibeci S., Heard R., Stewart G., and Booth D. Analysis of neutralizing antibodies to therapeutic interferon-beta in multiple sclerosis patients: a comparison of three methods in a large Australasian cohort. J. Immunol. Methods 310 1-2 (2006) 20 Mar 20, Dec 20
    • (2006) J. Immunol. Methods , vol.310 , Issue.1-2 , pp. 20
    • McKay, F.1    Schibeci, S.2    Heard, R.3    Stewart, G.4    Booth, D.5
  • 11
    • 0242333124 scopus 로고    scopus 로고
    • MxA gene expression analysis as an interferon-beta bioactivity measurement in patients with multiple sclerosis and the identification of antibody-mediated decreased bioactivity
    • Pachner A., Narayan K., Price N., Hurd M., and Dail D. MxA gene expression analysis as an interferon-beta bioactivity measurement in patients with multiple sclerosis and the identification of antibody-mediated decreased bioactivity. Mol. Diagn. 7 1 (2003) 17
    • (2003) Mol. Diagn. , vol.7 , Issue.1 , pp. 17
    • Pachner, A.1    Narayan, K.2    Price, N.3    Hurd, M.4    Dail, D.5
  • 12
    • 0242404144 scopus 로고    scopus 로고
    • Measurement of MxA mRNA or protein as a biomarker of IFNbeta bioactivity: detection of antibody-mediated decreased bioactivity (ADB)
    • Nov 11
    • Pachner A.R., Bertolotto A., and Deisenhammer F. Measurement of MxA mRNA or protein as a biomarker of IFNbeta bioactivity: detection of antibody-mediated decreased bioactivity (ADB). Neurology 61 9 Suppl 5 (2003) S24 Nov 11
    • (2003) Neurology , vol.61 , Issue.9 SUPPL. 5
    • Pachner, A.R.1    Bertolotto, A.2    Deisenhammer, F.3
  • 13
    • 23144458935 scopus 로고    scopus 로고
    • The importance of measuring IFNβ bioactivity: monitoring in MS patients and the effect
    • Sep
    • Pachner A.R., Dail D., Pak E., and Narayan K. The importance of measuring IFNβ bioactivity: monitoring in MS patients and the effect. J. Neuroimmunol. 166 1-2 (2005) 180 Sep
    • (2005) J. Neuroimmunol. , vol.166 , Issue.1-2 , pp. 180
    • Pachner, A.R.1    Dail, D.2    Pak, E.3    Narayan, K.4
  • 14
    • 0037180479 scopus 로고    scopus 로고
    • Evidence of interferon dose-response: Europian North American Compartative Efficacy; University of British Columbia MS/MRI Research Group. Randomized, comparative study of interferon beta-1a treatment regimens in MS: the EVIDENCE trial
    • EVIDENCE Study Group Nov 26
    • Panitch H., Goodin D.S., Francis G., Chang P., Coyle P.K., O'Connor P., Monaghan E., Li D., Weinshenker B., and EVIDENCE Study Group. Evidence of interferon dose-response: Europian North American Compartative Efficacy; University of British Columbia MS/MRI Research Group. Randomized, comparative study of interferon beta-1a treatment regimens in MS: the EVIDENCE trial. Neurology 59 10 (2002) 1496 Nov 26
    • (2002) Neurology , vol.59 , Issue.10 , pp. 1496
    • Panitch, H.1    Goodin, D.S.2    Francis, G.3    Chang, P.4    Coyle, P.K.5    O'Connor, P.6    Monaghan, E.7    Li, D.8    Weinshenker, B.9
  • 15
    • 70350594763 scopus 로고    scopus 로고
    • Pharm Res. Apr;15(4):641-9.
    • Pharm Res. Apr;15(4):641-9.
  • 21
    • 20444490479 scopus 로고    scopus 로고
    • Appearance and disappearance of neutralizing antibodies during interferon-beta therapy
    • and the Danish Multiple Sclerosis Study Group
    • Sorensen P.S., Koch-Henriksen N., Ross C., Clemmesen K.M., Bendtzen K., and and the Danish Multiple Sclerosis Study Group. Appearance and disappearance of neutralizing antibodies during interferon-beta therapy. Neurology 65 (2005) 33
    • (2005) Neurology , vol.65 , pp. 33
    • Sorensen, P.S.1    Koch-Henriksen, N.2    Ross, C.3    Clemmesen, K.M.4    Bendtzen, K.5
  • 22
    • 33750990488 scopus 로고    scopus 로고
    • Neutralizing antibodies hamper IFNbeta bioactivity and treatment effect on MRI in patients with MS
    • 1681-3 Nov. 14
    • Sorensen P.S., Tscherning T., Mathiesen H.K., Langkilde A.R., Ross C., Ravnborg M., and Bendtzen K. Neutralizing antibodies hamper IFNbeta bioactivity and treatment effect on MRI in patients with MS. Neurology 67 9 (2006) 1681-3 Nov. 14
    • (2006) Neurology , vol.67 , Issue.9
    • Sorensen, P.S.1    Tscherning, T.2    Mathiesen, H.K.3    Langkilde, A.R.4    Ross, C.5    Ravnborg, M.6    Bendtzen, K.7
  • 23
    • 27744509228 scopus 로고    scopus 로고
    • EFNS Task Force on Anti-IFN-beta Antibodies in Multiple Sclerosis Guidelines on use of anti-IFN-beta antibody measurements in multiple sclerosis: report of an EFNS Task Force on IFN-beta antibodies in multiple sclerosis
    • Nov
    • Sørensen P.S., Deisenhammer F., Duda P., Hohlfeld R., Myhr K.M., Palace J., Polman C., Pozzilli C., and Ross C. EFNS Task Force on Anti-IFN-beta Antibodies in Multiple Sclerosis Guidelines on use of anti-IFN-beta antibody measurements in multiple sclerosis: report of an EFNS Task Force on IFN-beta antibodies in multiple sclerosis. Eur. J. Neurol. 12 11 (2005) 817 Nov
    • (2005) Eur. J. Neurol. , vol.12 , Issue.11 , pp. 817
    • Sørensen, P.S.1    Deisenhammer, F.2    Duda, P.3    Hohlfeld, R.4    Myhr, K.M.5    Palace, J.6    Polman, C.7    Pozzilli, C.8    Ross, C.9
  • 24
    • 0032576752 scopus 로고    scopus 로고
    • Axonal transection in the lesions of multiple sclerosis
    • Trapp B.D., Peterson J., Ransohoff R.M., et al. Axonal transection in the lesions of multiple sclerosis. New Engl. J. Med. 338 (1998) 278
    • (1998) New Engl. J. Med. , vol.338 , pp. 278
    • Trapp, B.D.1    Peterson, J.2    Ransohoff, R.M.3
  • 25
    • 0003686264 scopus 로고
    • WHO Expert Committee on Biological Standardisation. Thirty-Fifth Report, World Health Organization, Geneva
    • WHO Expert Committee on Biological Standardisation. Thirty-Fifth Report. WHO Technical Report Series vol. 725 (1985), World Health Organization, Geneva
    • (1985) WHO Technical Report Series , vol.725


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.