Genetic stability, active constituent, and pharmacoactivity of Salvia miltiorrhiza hairy roots and wild plant

Zeitschrift fur Naturforschung - Section C Journal of Biosciences

Volumn 64, Issue 7-8, 2009, Pages 557-563

  Yuan, Yuan ^a   Liu, Yunjun ^b   Lu, Dongmei ^a   Huang, Luqi ^a   Liang, Rixin ^a   Yang, Zhaochun ^a   Chen, Shunqin ^a  

^a INSTITUTE OF CHINESE MATERIA MEDICA   (China)

^b INSTITUTE OF PLANT PROTECTION   (China)

Author keywords

Genetic stability; Hairy roots; Pharmacoactivity; Salvia miltiorrhiza

Indexed keywords

RATTUS; SALVIA MILTIORRHIZA;

BACTERIAL DNA; HERBACEOUS AGENT; PHENANTHRENE DERIVATIVE; PLANT DNA; PLANT EXTRACT; PRIMER DNA; T DNA; T-DNA; TANSHINONE;

ANIMAL; ARTICLE; ASIA; CELL CULTURE; CHEMISTRY; DRUG EFFECT; GENETICS; HEART; HEART MUSCLE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOLATION AND PURIFICATION; METABOLISM; PLANT GENOME; PLANT ROOT; POLYMERASE CHAIN REACTION; RAT; SALVIA MILTIORRHIZA;

ANIMALS; ASIA; CELLS, CULTURED; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DNA PRIMERS; DNA, BACTERIAL; DNA, PLANT; DRUGS, CHINESE HERBAL; GENOME, PLANT; HEART; MYOCARDIUM; PHENANTHRENES; PLANT EXTRACTS; PLANT ROOTS; POLYMERASE CHAIN REACTION; RATS; SALVIA MILTIORRHIZA;

EID: 70350613078     PISSN: 09395075     EISSN: None     Source Type: Journal    
DOI: 10.1515/znc-2009-7-815     Document Type: Article

References (14)

1. Alan A. R., Zeng H., Assani A., Shi W. L., McRae H. E., and Murch S. J. (2007), Assessment of genetic stability of the germplasm lines of medicinal plant Scutellaria baicalensis Georgi (Huang-qin) in long-term, in vitro maintained cultures. Plant Cell Rep. 26, 1345-1355.
2. Baiza A., Quiroz-Moreno A., Ruiz J., and Loyola-Vargas V. (1999), Genetic stability of hairy root cultures of Datura stramonium. Plant Cell Tiss. Org. Cult. 59, 9-17.
3. Bonhomme V., Laurain-Mattar D., and Fliniaux M. A. (2000), Effects of the rol C gene on hairy root: induction development and tropane alkaloid production by Atropa belladonna. J. Nat. Prod. 63, 1249-1252.
4. Dolezel J. and Bartos J. (2005), Plant DNA flow cytometry and estimation of nuclear genome size. Ann. Bot. (London) 95, 99-110.
5. Dolezel J., Bartos J., Voglmayr H., and Greilhuber J. (2003), Nuclear DNA content and genome size of trout and human. Cytometry A 51, 127-128.
6. Fu C. X., Xu Y. J., Zhao D. X., and Ma F. S. (2006), A comparison between hairy root cultures and wild plants of Saussurea involucrata in phenylpropanoids production. Plant Cell Rep. 24, 750-754.
7. Lin L. Z., Wu C. L., Lu Z., Huang Y. R., Zhuang J. G., and Zhou Z. N. (2000), The studies on protective effects of SM against myocardial hypoxia/reoxygenation injury. Zhongguo Ying Yong Sheng Li Xue Za Zhi 16, 324-326.
8. Peebles C. A., Gibson S. I., Shanks J. V., and San K. Y. (2007), Long-term maintenance of a transgenic Catharanthus roseus hairy root line. Biotechnol. Prog. 23, 1517-1518.
9. Walker D. J., Monino I., and Correal E. (2006), Genome size in Bituminaria bituminosa (L.) C. H. Stirton (Fabaceae) populations: separation of "true" differences from environmental effects on DNA determination. Environ. Exp. Bot. 55, 258-265.
10. Wei L., Jianhua L., Mala A., Rongqian W., Dazhi C., and Lihong Y. (2007), A cardiovascular drug rescues mice from lethal sepsis by selectively attenuating a late-acting proinflammatory mediator, high mobility group box 1. J. Immunol. 178, 3856-3864.
11. Wu Y. Q., Taliaferro C. M., Bai G. H., Martin D. L., Anderson J. A., and Anderson M. P. (2006), Genetic analyses of Chinese cynodon accessions by flow cytometry and AFLP markers. Crop Sci. 46, 917-926.
12. Yuan Y., Yang Z. C., Lu D. M., Chen M., and Huang L. Q. (2008), Measurement of Salvia miltiorrhiza hairy root nuclear DNA content with flow cytometry method. Chin. J. Exp. Trad. Med. Form. 12, 24-25.
13. Zeng L., Liang H., Chen Y., Liang H., and Pan Y. (2006), Primary study on the distribution of tanshinone IIA and salvianolic acid B in radix Salvia miltiorrhiza. Res. Pract. Chin. Med. 20, 7-9.
14. Zhang Y. L., Song J. Y., Liu G. L., and Liu H. L., (1995), Establishment of hairy root culture and production of tanshinone in Salvia miltiorrhiza, China. J. Chin. Material Med. 20, 269-271.