The characterization and comparison of spray-dried mannitol samples characterization of spray-dried mannitol

Drug Development and Industrial Pharmacy

Volumn 35, Issue 6, 2009, Pages 712-718

  Hulse, Wendy L ^a   Forbes, Robert T ^a   Bonner, Michael C ^a   Getrost, Matthias ^b  

^a UNIVERSITY OF BRADFORD   (United Kingdom)

^b Merck Chemicals Ltd   (United Kingdom)

Author keywords

Thermal analysis

Indexed keywords

MANNITOL;

ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; DIFFERENTIAL SCANNING CALORIMETRY; DRUG CONFORMATION; DRUG FORMULATION; DRUG STORAGE; DRUG STRUCTURE; DRUG SYNTHESIS; FOURIER TRANSFORMATION; MICROCALORIMETRY; SCANNING ELECTRON MICROSCOPY; SPRAY DRYING; THERMAL ANALYSIS; THERMOGRAVIMETRY; X RAY POWDER DIFFRACTION;

CALORIMETRY; CALORIMETRY, DIFFERENTIAL SCANNING; CHEMISTRY, PHARMACEUTICAL; CRYSTALLIZATION; DRUG STORAGE; EXCIPIENTS; MANNITOL; POWDERS; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; THERMOGRAVIMETRY; X-RAY DIFFRACTION;

EID: 70350608409     PISSN: 03639045     EISSN: 15205762     Source Type: Journal    
DOI: 10.1080/03639040802516491     Document Type: Article

References (20)

1. Kibbe AE, ed. (2000). Handbook of pharmaceutical excipients. 3rd ed. London: Pharmaceutical Press.
2. Berman HM, Rosenstein GA. (1968). The crystal structures of the and forms of D-mannitol. Acta Crystallogr B, 24:442-449
3. Debord B, Lefebvre C, Guyot-Hermann AM. (1987). Study of the different crystalline forms of mannitol: Comparative behaviour under compression. Drug Dev Ind Pharm, 13:1533-1546
4. Giron D. (1990). Le polymorphisme des excipients. STP Pharma, 6:92-93
5. Grindley TB, McKinnon MS, Wasylishen RE. (1990). Towards understanding 13C-NMR chemical shifts of carbohydrates in the solid state, the spectra of D-mannitol polymorphs and DL-mannitol. Carbohydr Res, 197:41-52.
6. Jones FT, Lee KS. (1970). The optical and crystallographic properties of three phases of mannitol. Microscope, 18:279-285
7. Kim HS, Jeffrey GA, Rosenstein RD. (1986). The crystal structure of the K form of D-mannitol. Acta Crystallogr B, 24:1449-1455
8. Walter-Levy L. (1968). Cristallochimie. Sur les variétés cristallines du D-mannitol. C R Acad Sci Paris Ser C, 267:1779-1782
9. Haleblian J, McCrone W. (1969). Pharmaceutical applications of polymorphism. J Pharm Sci, 58:911-929
10. Brittain HG. (2001). X-ray diffraction III: Pharmaceutical applications of x-ray powder diffraction. Spectroscopy, 16:14.
11. Kim AI, Akers MJ, Nail SL. (1998). The physical state of mannitol after freeze drying: Effects of mannitol concentration, freezing rate, and a noncrystallizing cosolute. J Pharm Sci, 87:931-935
12. Roberts SNC, Williams AC, Grimsey IM, Booth SW. (2002). Quantitative analysis of mannitol polymorphs. FT-Raman spectroscopy. J Pharm Biomed Anal, 28:1135-1147
13. Burger A, Henck J, Hetz S, Rollinger JM, Weissnicht AA, Stottner H. (2000). Energy/temperature diagram and compression behaviour of the polymorphs of D-mannitol. J Pharm Sci, 89:457-468
14. Yoshinari T, Forbes RT, York P. (2002). Moisture induced polymorphic transition of mannitol and its morphological transformation. Int J Pharm, 247:69-77.
15. Pellow-Jarmen MV, Hendra PJ, Lehnert RJ. (1996). The dependence of Raman signal intensity on particle size for crystal powders. Vib Spectrosc, 12:257-261
16. Reis MM, Araujo PHH, Sayer C, Giudici R. (2003). Evidences of correlation between polymer particle size and Raman scattering. Polymer, 44:6123-6128
17. McCauley JA, Brittain HG. (1995). Thermal methods of analysis. In: Brittain HG, ed. Physical characterisation of pharmaceutical solids. New York: Marcel Dekker, 223.
18. Shekonov BY, York P. (2000). Crystallisation processes in pharmaceutical technology and drug delivery design. J Cryst Growth, 211:122-136
19. Gaisford S, Buckton G. (2001). Application of microcalorimetry for physical processes in pharmaceuticals. Thermochim Acta, 380:185-198
20. Yoshinari T, Forbes RT, York P, Kawashima Y. (2003). Crystallisation of amorphous mannitol is retarded using boric acid. Int J Pharm, 258:109-120