Intrahepatic long-term persistence of parvovirus B19 and its role in chronic viral hepatitis

Journal of Medical Virology

Volumn 81, Issue 12, 2009, Pages 2079-2088

  Wang, Chun ^a,b   Heim, Albert ^a   Schlaphoff, Verena ^a   Suneetha, P V ^a   Stegmann, Kerstin A ^a   Jiang, Hong ^a   Krueger, Martin ^a   Fytili, Paraskevi ^a   Schulz, Thomas ^a   Cornberg, Markus ^a   Kandolf, Reinhard ^c   Manns, Michael P ^a   Bock, C Thomas ^c   Wedemeyer, Heiner ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b TONGJI UNIVERSITY   (China)

^c UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

Author keywords

Cellular immunity; Chronic hepatitis C; Intrahepatic persistence; Parvovirus B19

Indexed keywords

RECOMBINANT ALPHA2B INTERFERON; RIBAVIRIN;

ADULT; AGED; ARTICLE; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; ERYTHEMA INFECTIOSUM; FEMALE; GENE AMPLIFICATION; HEPATITIS B; HEPATITIS C; HUMAN; HUMAN TISSUE; LIVER BIOPSY; MAJOR CLINICAL STUDY; MALE; PARVOVIRUS; PREVALENCE; VIRUS HEPATITIS;

ADULT; AGED; ANTIBODIES, VIRAL; CD4-POSITIVE T-LYMPHOCYTES; DISEASE PROGRESSION; DNA, VIRAL; FEMALE; GERMANY; HEPATITIS B, CHRONIC; HEPATITIS C, CHRONIC; HUMANS; LIVER; MALE; MIDDLE AGED; PARVOVIRIDAE INFECTIONS; PARVOVIRUS B19, HUMAN; TIME FACTORS;

HEPATITIS B VIRUS; HEPATITIS C VIRUS; PARVOVIRUS;

EID: 70350576838     PISSN: 01466615     EISSN: 10969071     Source Type: Journal    
DOI: 10.1002/jmv.21638     Document Type: Article

References (46)

1. Abe K, Kiuchi T, Tanaka K, Edamoto Y, Aiba N, Sata T. 2007. Characterization of erythrovirus B19 genomes isolated in liver tissues from patients with fulminant hepatitis and biliary atresia who underwent liver transplantation. Int J Med Sci 4:105-109. (Pubitemid 46557523)
2. Aberle JH, Perstinger G, Weseslindtner L, Sinzinger U, Gurguta C, Steindl-Munda P, Kundi M, Popow-Kraupp T, Ferenci P, Holzmann H. 2007. CD4+ T cell responses in patients with chronic hepatitis C undergoing peginterferon/ribavirin therapy correlate with faster, but not sustained, viral clearance. J Infect Dis 195:1315-1319. (Pubitemid 46649617)
3. Anderson MJ, Jones SE, Fisher-Hoch SP, Lewis E, Hall SM, Bartlett CL, Cohen BJ, Mortimer PP, Pereira MS. 1983. Human parvovirus, the cause of erythema infectiosum (fifth disease)? Lancet 1:1378.
4. Anderson MJ, Higgins PG, Davis LR, Willman JS, Jones SE, Kidd IM, Pattison JR, Tyrrell DA. 1985. Experimental parvoviral infection in humans. J Infect Dis 152:257-265.
5. Bain C, Fatmi A, Zoulim F, Zarski JP, Trepo C, Inchauspe G. 2001. Impaired allostimulatory function of dendritic cells in chronic hepatitis C infection. Gastroenterology 120:512-524. (Pubitemid 32147649)
6. Cassinotti P, Burtonboy G, Fopp M, Siegl G. 1997. Evidence for persistence of human parvovirus B19 DNA in bone marrow. J Med Virol 53:229-232. (Pubitemid 28201830)
7. Chevrel G, Calvet A, Belin V, Miossec P. 2000. Dermatomyositis associated with the presence of parvovirus B19 DNA in muscle. Rheumatology (Oxford) 39:1037-1039.
8. Cossart YE, Field AM, Cant B, Widdows D. 1975. Parvovirus-like particles in human sera. Lancet 1:72-73.
9. Crawford MP, Yan SX, Ortega SB, Mehta RS, Hewitt RE, Price DA, Stastny P, Douek DC, Koup RA, Racke MK, Karandikar NJ. 2004. High prevalence of autoreactive, neuroantigen-specific CD8+ T cells in multiple sclerosis revealed by novel flow cytometric assay. Blood 103:4222-4231. (Pubitemid 38685367)
10. Drago F, Semino M, Rampini P, Rebora A. 1999. Parvovirus B19 infection associated with acute hepatitis and a purpuric exanthem. Br J Dermatol 141:160-161. (Pubitemid 29333716)
11. Eis-Hubinger AM, Reber U, Abdul-Nour T, Glatzel U, Lauschke H, Putz U. 2001. Evidence for persistence of parvovirus B19 DNA in livers of adults. J Med Virol 65:395-401.
12. Franssila R, Hokynar K, Hedman K. 2001. T helper cell-mediated in vitro responses of recently and remotely infected subjects to a candidate recombinant vaccine for human parvovirus b19. J Infect Dis 183:805-809. (Pubitemid 32171756)
13. Gan YJ, Razzouk BI, Su T, Sixbey JW. 2002. A defective, rearranged Epstein-Barr virus genome in EBER-negative and EBER-positive Hodgkin's disease. Am J Pathol 160:781-786. (Pubitemid 34224567)
14. He Z, Zhuang H, Wang X, Song S, Dong Q, Yan J, Buehring GC, Luo G. 2003. Retrospective analysis of non-A-E hepatitis: Possible role of hepatitis B and C virus infection. J Med Virol 69:59-65. (Pubitemid 35403654)
15. Heegaard ED, Petersen BL, Heilmann CJ, Hornsleth A. 2002. Prevalence of parvovirus B19 and parvovirus V9 DNA and antibodies in paired bone marrow and serum samples from healthy individuals. J Clin Microbiol 40:933-936. (Pubitemid 34208648)
16. Hillingso JG, Jensen IP, Tom-Petersen L. 1998. Parvovirus B19 and acute hepatitis in adults. Lancet 351:955-956. (Pubitemid 28138472)
17. Hsu TC, Chen TY, Lin MC, Tzang BS, Tsay GJ. 2005. Human parvovirus B19 infection in patients with chronic hepatitis B or hepatitis C infection. J Gastroenterol Hepatol 20:733-738. (Pubitemid 40733368)
18. Karetnyi YV, Beck PR, Markin RS, Langnas AN, Naides SJ. 1999. Human parvovirus B19 infection in acute fulminant liver failure. Arch Virol 144:1713-1724. (Pubitemid 29490033)
19. Kasprowicz V, Isa A, Tolfvenstam T, Jeffery K, Bowness P, Klenerman P. 2006. Tracking of peptide-specific CD4+ T-cell responses after an acute resolving viral infection: A study of parvovirus B19. J Virol 80:11209-11217. (Pubitemid 44706560)
20. Kuhl U. 2005. Antiviral treatment of myocarditis and acute dilated cardiomyopathy. Heart Fail Clin 1:467-474.
21. Langnas AN, Markin RS, Cattral MS, Naides SJ. 1995. Parvovirus B19 as a possible causative agent of fulminant liver failure and associated aplastic anemia. Hepatology 22:1661-1665.
22. Lehmann U, Wingen LU, Brakensiek K, Wedemeyer H, Becker T, Heim A, Metzig K, Hasemeier B, Kreipe H, Flemming P. 2007. Epigenetic defects of hepatocellular carcinoma are already found in non-neoplastic liver cells from patients with hereditary haemochromatosis. Hum Mol Genet 16:1335-1342. (Pubitemid 47055129)
23. Lindblom A, Isa A, Norbeck O, Wolf S, Johansson B, Broliden K, Tolfvenstam T. 2005. Slow clearance of human parvovirus B19 viremia following acute infection. Clin Infect Dis 41:1201-1203. (Pubitemid 41429486)
24. Lundqvist A, Tolfvenstam T, Bostic J, Soderlund M, Broliden K. 1999a. Clinical and laboratory findings in immunocompetent patients with persistent parvovirus B19 DNA in bone marrow. Scand J Infect Dis 31:11-16. (Pubitemid 29253571)
25. Lundqvist A, Tolfvenstam T, Brytting M, Stolt CM, Hedman K, Broliden K. 1999b. Prevalence of parvovirus B19 DNA in bone marrow of patients with haematological disorders. Scand J Infect Dis 31:119-122. (Pubitemid 29355516)
26. Manns MP, Wedemeyer H, Cornberg M. 2006. Treating viral hepatitis C: Efficacy, side effects, and complications. Gut 55:1350-1359. (Pubitemid 44277369)
27. Meyer MF, Lehmann M, Cornberg M, Wiegand J, Manns MP, Klade C, Wedemeyer H. 2007. Clearance of low levels of HCV viremia in the absence of a strong adaptive immune response. Virol J 4:58. (Pubitemid 47055862)
28. Mitchell LA, Leong R, Rosenke KA. 2001. Lymphocyte recognition of human parvovirus B19 non-structural (NS1) protein: Associations with occurrence of acute and chronic arthropathy? J Med Microbiol 50:627-635.
29. Nikkari S, Roivainen A, Hannonen P, Mottonen T, Luukkainen R, Yli-Jama T, Toivanen P. 1995. Persistence of parvovirus B19 in synovial fluid and bone marrow. Ann Rheum Dis 54:597-600.
30. Norja P, Eis-Hubinger AM, Soderlund-Venermo M, Hedman K, Simmonds P. 2008. Rapid sequence change and geographical spread of human parvovirus B19: Comparison of B19 virus evolution in acute and persistent infections. J Virol 82:6427-6433. (Pubitemid 351875120)
31. Rehermann B, Nascimbeni M. 2005. Immunology of hepatitis B virus and hepatitis C virus infection. Nat Rev Immunol 5:215-229.
32. Semmo N, Krashias G, Willberg C, Klenerman P. 2007. Analysis of the relationship between cytokine secretion and proliferative capacity in hepatitis C virus infection. J Viral Hepat 14:492-502. (Pubitemid 46944474)
33. So K, Macquillan G, Garas G, Delriviere L, Mitchell A, Speers D, Mews C, Augustson B, de Boer WB, Baker D, Jeffrey GP. 2007. Urgent liver transplantation for acute liver failure due to parvovirus B19 infection complicated by primary Epstein-Barr virus and cytomegalovirus infections and aplastic anaemia. Intern Med J 37:192-195. (Pubitemid 46256032)
34. Sokal EM, Melchior M, Cornu C, Vandenbroucke AT, Buts JP, Cohen BJ, Burtonboy G. 1998. Acute parvovirus B19 infection associated with fulminant hepatitis of favourable prognosis in young children. Lancet 352:1739-1741. (Pubitemid 28534956)
35. Suneetha PV, Schlaphoff V, Wang C, Stegmann KA, Fytili P, Sarin SK, Manns MP, Cornberg M, Wedemeyer H. 2009. Effect of peptide pools on effector functions of antigen-specific CD8+ T cells. J Immunol Methods 342:33-48.
36. Toan NL, Song le H, Kremsner PG, Duy DN, Binh VQ, Duechting A, Kaiser H, Torresi J, Kandolf R, Bock CT. 2006. Co-infection of human parvovirus B19 in Vietnamese patients with hepatitis B virus infection. J Hepatol 45:361-369. (Pubitemid 44160629)
37. Urbani S, Amadei B, Fisicaro P, Pilli M, Missale G, Bertoletti A, Ferrari C. 2005. Heterologous T cell immunity in severe hepatitis C virus infection. J Exp Med 201:675-680. (Pubitemid 40395112)
38. von Poblotzki A, Gerdes C, Reischl U, Wolf H, Modrow S. 1996. Lymphoproliferative responses after infection with human parvovirus B19. J Virol 70:7327-7330. (Pubitemid 26307462)
39. Vuorinen T, Lammintausta K, Kotilainen P, Nikkari S. 2002. Presence of parvovirus B19 DNA in chronic urticaric and healthy human skin. J Clin Virol 25:217-221. (Pubitemid 35287247)
40. Wandinger K, Jabs W, Siekhaus A, Bubel S, Trillenberg P, Wagner H, Wessel K, Kirchner H, Hennig H. 2000. Association between clinical disease activity and Epstein-Barr virus reactivation in MS. Neurology 55:178-184. (Pubitemid 30604615)
41. Wedemeyer H, Mizukoshi E, Davis AR, Bennink JR, Rehermann B. 2001. Cross-reactivity between hepatitis C virus and influenza A virus determinant-specific cytotoxic T cells. J Virol 75:11392-11400. (Pubitemid 33063230)
42. Wedemeyer H, He XS, Nascimbeni M, Davis AR, Greenberg HB, Hoofnagle JH, Liang TJ, Alter H, Rehermann B. 2002. Impaired effector function of hepatitis C virus-specific CD8+ T cells in chronic hepatitis C virus infection. J Immunol 169:3447-3458. (Pubitemid 35013196)
43. Welsh RM, Kim SK, Cornberg M, Clute SC, Selin LK, Naumov YN. 2006. The privacy of T cell memory to viruses. Curr Top Microbiol Immunol 311:117-153.
44. Wong S, Young NS, Brown KE. 2003. Prevalence of parvovirus B19 in liver tissue: No association with fulminant hepatitis or hepatitis-associated aplastic anemia. J Infect Dis 187:1581-1586.
45. Yoto Y, Kudoh T, Haseyama K, Suzuki N, Chiba S. 1996. Human parvovirus B19 infection associated with acute hepatitis. Lancet 347:868-869. (Pubitemid 26099540)
46. Young NS, Brown KE. 2004. Parvovirus B19. N Engl J Med 350:586-597.