Elevated expression of catechol-O-methyltransferase is associated with labor and increased prostaglandin E2 production by human fetal membranes

American Journal of Obstetrics and Gynecology

Volumn 201, Issue 5, 2009, Pages 496.e1-496.e7

  Harirah, Hassan ^a   Thota, Chandrasekhar ^c   Wentz, Melissa J ^b   Zaman, Wahiduz ^a   Al Hendy, Ayman ^c  

^a University of Texas Medical Branch School of Medicine   (United States)

^b Texas Nerve and Paralysis Institute   (United States)

^c MEHARRY MEDICAL COLLEGE   (United States)

Author keywords

catechol O methyltrasferase; fetal membranes; term labor

Indexed keywords

2' FLUORO 3,4 DIHYDROXY 5 NITROBENZOPHENONE; CATECHOL METHYLTRANSFERASE; CATECHOL METHYLTRANSFERASE INHIBITOR; PROSTAGLANDIN E2; RNA;

AMNION; ARTICLE; CESAREAN SECTION; CHORION; CONTROLLED STUDY; DECIDUA; DISEASE ASSOCIATION; ELECTIVE SURGERY; ENZYME INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME MECHANISM; EXPLANT; FEMALE; FETUS; FETUS MEMBRANE; GESTATIONAL AGE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOLOCALIZATION; IN VITRO STUDY; LABOR; PRIORITY JOURNAL; PROSTAGLANDIN RELEASE; PROSTAGLANDIN SYNTHESIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; REAL TIME POLYMERASE CHAIN REACTION; RNA EXTRACTION; VAGINAL DELIVERY; WESTERN BLOTTING;

CATECHOL O-METHYLTRANSFERASE; DINOPROSTONE; EXTRAEMBRYONIC MEMBRANES; FEMALE; HUMANS; LABOR, OBSTETRIC; PREGNANCY;

EID: 70350575756     PISSN: 00029378     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ajog.2009.05.041     Document Type: Article

References (30)

1. Challis J.R.G., and Mitchell B.F. Steroid production by the fetal membranes in relation to the onset of parturition. In: McNillis D., Challis J.R.G., McDonald P.C., Nathanielsz P.W., and Roberts J.M. (Eds). The onset of labour: cellular and integrative mechanisms (1988), Perinatology Press, Ithaca, NY 233-253
2. Boroditsky R.S., Reyes F.I., Winter J.S.D., and Faiman C. Maternal serum estrogen and progesterone concentrations preceding normal labor. Obstet Gynecol 51 (1978) 686-691
3. Mitchell B.F., Challis J.R.G., and Lukash L. Progesterone synthesis by human amnion, chorion, and deciduas at term. Am J Obstet Gynecol 157 (1987) 349-353
4. Strickler R.C., and Tobias B. Estradiol 17 beta-dehydrogenase and 20 alpha-hydroxysteroid dehydrogenase from human placental cytosol: one enzyme with two activities?. Steroids 36 (1980) 243-253
5. Romano W.M., Lukash L.A., Challis J.R.G., and Mitchell B.F. Substrate utilization for estrogen synthesis by human fetal membranes and deciduas. Am J Obstet Gynecol 155 (1986) 1170-1175
6. Dong Y.L., and Yallampalli C. Pregnancy and exogenous steroid treatments modulate the expression of relaxant EP2 and contractile FP receptors in the rat uterus. Biol Reprod 62 (2000) 533-539
7. Fang X., Wong S., and Mitchell B.F. Relationships among sex steroids, oxytocin, and their receptors in the rat uterus during late gestation and parturition. Endocrinology 137 (1996) 3213-3219
8. Challis J.R.G., Matthews S.G., Gibb W., and Lye S.J. Endocrine and paracrine regulation of birth at term and preterm. Endocrine Rev 21 (2000) 514-550
9. Zhu B.T., and Conney A.H. Functional role of estrogen metabolism in target cells: review and perspectives. Carcinogenesis 19 (1998) 1-27
10. Männistö P.T., and Kaakkola S. Catechol-o-methyltransferase (COMT): biochemistry, molecular biology, pharmacology, and clinical efficacy of the new selective COMT inhibitors. Pharmacol Rev 51 (1999) 593-628
11. Lachman H.M., Papolos D.F., Saito T., Yu Y.M., Szumlanski C.L., and Weinshilboum R.M. Human catechol-O-methyltransferase pharmacogenetics: description of a functional polymorphism and its potential application to neuropsychiatric disorders. Pharmacogenetics 6 (1996) 243-250
12. Tekpetey F.R., and Armstrong D.T. Catecholestrogen modulation of steroid production by rat luteal cells: mechanism of action. Mol Cell Endocrinol 101 (1994) 49-57
13. Creveling C.R. The role of catechol-O-methyltransferase in the inactivation of catecholestrogen. Cell Mol Neurobiol 23 (2003) 289-291
14. Kanasaki K., Palmsten K., Sugimato H., et al. Defeciency in catechol-O-methyltransferase and 2-methoxyestradiol is associated with pre-eclampsia. Nature 453 (2008) 1117-1121
15. Wentz M.J., Jamaluddin M., Garfield R.E., and Al-Hendy A. Regulation of catechol-O-methyltransferase expression in human myometrial cells. Obstet Gynecol 108 (2006) 1439-1447
16. Schneider J., Huh M.M., Bradlow H.L., and Fishman J. Antiestrogen action of 2-hydrosyestrone on MCF-7 human breast cancer cells. J Biol Chem 259 (1984) 480-485
17. Wentz M., Shao-Qing S., Leili S., et al. Treatment with an inhibitor of catechol-O-methyltransferase activity reduces preterm birth and impedes cervical resistance to stretch in pregnant rats. Reproduction 134 (2007) 831-839
18. Salih S.M., Jamaluddin M., Salama S.A., Fadl A.A., Nagamani M., and Al-Hendy A. Regulation of catechol O-methyltransferase expression in granulosa cells: a potential role for follicular arrest in polycystic ovary syndrome. Fertil Steril 89 (2008) 1414-1421
19. Salih S.M., Salama S.A., Fadl A.A., Nagamani M., and Al-Hendy A. Expression and cyclic variations of catechol-O-methyl transferase in human endometrial stroma. Fertil Steril 90 (2008) 789-797
20. Casey M.L., and MacDonald P.C. Characterization of catechol-O-methyltransferase activity in human uterine decidua vera tissue. Am J Obstet Gynecol 145 (1983) 453-457
21. Barnea E.R., MacLusky N.J., DeCherney A.H., and Naftolin F. Catechol-O-methyl transferase activity in the human term placenta. Am J Perinatol 5 (1988) 121-127
22. Bradlow L.H. 2-Hydroxyesterone: the "good" estrogen. J Endocrinol 150 (1996) S259-S265
23. Vandewalle B. Opposite effects of estrogen and catecholestrogen on hormone-sensitive breast cancer cell growth and differentiation. Mol Cell Endocrionol 61 (1989) 239-246
24. Sutherland T.E., Schuliga M., Harris T., et al. 2-methoxyestradiol is an estrogen receptor agonist that supports tumor growth in murine xenograft models of breast cancer. Clin Cancer Res 11 (2005) 1722-1732
25. Castren O., and Saarikoski S. The simultaneous function of catechol-O-methyltransferase and monoamine oxidase in human placenta. Acta Obstet Gynecol Scand 53 (1974) 41-47
26. Hirst J.J., Teixeira F.J., Zakar T., and Olson D.M. Prostaglandin H synthase-2 expression increases in human gestational tissues with spontaneous labour onset. Reprod Fertil Dev 7 (1995) 633-637
27. Gibb W., and Sun M. Localization of prostaglandin H synthase type 2 protein and mRNA in term human fetal membranes and decidua. J Endocrinol 50 (1996) 497-503
28. Olson D.M., Smieja Z., Zakar T., MacLeod E.A., Walton J., and Milne K. Regulation of prostaglandin synthesis in the human amnion. Reprod Fertil Dev 3 (1991) 413-419
29. Thota C., Pullman S., and Al-Hendy A. Catechol-O-Methyltransferase regulates the expression of contractile associated proteins in term human myometrial cells (2008) Presented at: 11th RCMI International Symposium on Health Disparities; Honolulu, HI; Dec. 1-4
30. Barchiesi F., Jackson E.K., Fingerle J., Gillespie D.G., Odermatt B., and Dubey R.K. 2-Methoxyestradiol, an estradiol metabolite, inhibits neointima formation and smooth muscle cell growth via double blockade of the cell cycle. Circ Res 99; (2006) 266-274