Pilot study evaluating a progesterone vaginal ring for luteal-phase replacement in donor oocyte recipients

Fertility and Sterility

Volumn 92, Issue 5, 2009, Pages 1600-1605

  Stadtmauer, Laurel ^a   Harrison, Diane D ^b   Boyd, Jeannine ^a   Bocca, Silvina ^a   Oehninger, Sergio ^a  

^a EASTERN VIRGINIA MEDICAL SCHOOL   (United States)

^b Duramed Research Inc   (United States)

Author keywords

Donor eggs; endometrial biopsy; pregnancy; progesterone; ring; vaginal

Indexed keywords

ESTRADIOL; LEUPRORELIN; PROGESTERONE;

ABDOMINAL PAIN; ADULT; ARTICLE; CELL CYCLE PROGRESSION; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG DOSAGE FORM COMPARISON; DRUG INDUCED HEADACHE; DRUG SAFETY; DRUG TOLERABILITY; DYSMENORRHEA; DYSPEPSIA; ENDOMETRIUM; ENDOMETRIUM BIOPSY; FEMALE; GEL; HUMAN; HUMAN TISSUE; IMPLANTABLE PORT SYSTEM; LIVE BIRTH; LUTEAL PHASE; MENSTRUAL CYCLE; METRORRHAGIA; NAUSEA; OOCYTE DONATION; OOCYTE RETRIEVAL; PELVIS PAIN SYNDROME; PHASE 2 CLINICAL TRIAL; PREGNANCY RATE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RECIPIENT; SINGLE DRUG DOSE; TREATMENT DURATION; UPPER RESPIRATORY TRACT INFECTION; UTERINE CERVIX DISEASE; VAGINA RING;

ADMINISTRATION, INTRAVAGINAL; ADULT; CONTRACEPTIVE DEVICES, FEMALE; EMBRYO TRANSFER; FEMALE; FERTILITY AGENTS, FEMALE; HORMONE REPLACEMENT THERAPY; HUMANS; INFERTILITY; LUTEAL PHASE; MIDDLE AGED; OOCYTE DONATION; PILOT PROJECTS; PREGNANCY; PREGNANCY RATE; PROGESTERONE; TRANSPLANTATION;

EID: 70350573608     PISSN: 00150282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2008.08.085     Document Type: Article

References (20)

1. Centers for Disease Control and Prevention. 2005 assisted reproductive technology success rates, national summary and fertility clinic reports. Available at: http://www.cdc.gov/reproductivehealth/ART01/index.htm. Accessed 1 June 2008.
2. Klein J., and Sauer M.V. Oocyte donation. Best Pract Res Clin Obstet Gynaecol 16 (2002) 277-291
3. Penzias A.S. Luteal phase support. Fertil Steril 77 (2002) 318-323
4. Yanushpolsky E., Hurwitz S., Greenberg L., Racowsky C., and Hornstein M.D. Comparison of Crinone 8% intravaginal gel and intramuscular progesterone supplementation for in vitro fertilization/embryo transfer in women under age 40: interim analysis of a prospective randomized trial. Fertil Steril 89 (2008) 485-487
5. Gibbons W.I., Toner J.P., Hamacher P., and Kolm P. Experience with a novel vaginal progesterone preparation in a donor oocyte program. Fertil Steril 69 (1998) 96-101
6. Levine H. Luteal support in IVF using the novel vaginal progesterone gel Crinone 8%: results of an open-label trial in 1184 women from 16 US centers. Fertil Steril 74 (2000) 836-837
7. Miles R.A., Paulson R.J., Lobo R.A., Press M.F., Dahmoush L., and Sauer M.V. Pharmacokinetics and endometrial tissue levels of progesterone after administration by intramuscular and vaginal routes: a comparative study. Fertil Steril 62 (1994) 485-490
8. Bulletti C., de Ziegler D., Flamigni C., Giacomucci E., Polli V., Bolelli G., et al. Targeted drug delivery in gynaecology: the first uterine pass effect. Hum Reprod 12 (1997) 1073-1079
9. Toner J.P. Vaginal delivery of progesterone in donor oocyte therapy. Hum Reprod 15 Suppl 1 (2000) 166-171
10. Columbia Laboratories. Crinone US prescribing information (2006), Columbia Laboratories, Livingston, NJ
11. Ferring Pharmaceuticals. Endometrin US prescribing information (2007), Ferring Pharmaceuticals, Parsippany, NJ
12. Solvay Pharmaceuticals. Prometrium US prescribing information (2008), Solvay Pharmaceuticals, Marietta, GA
13. Zegers-Hochschild F., Balmaceda J.P., Fabres C., Alam V., Mackenna A., Fernandez E., et al. Prospective randomized trial to evaluate the efficacy of a vaginal ring releasing progesterone for IVF and oocyte donation. Hum Reprod 15 (2000) 2093-2097
14. Dragonas C., Maltaris T., Binder H., Mueller A., Cupsti S., Hoffmann I., et al. Progesterone bioavailability with a progesteron-releasing silicone vaginal ring in IVF candidates. Eur J Med Res 12 (2007) 264-267
15. Noyes R.W., Hertig A.T., and Rock J. Dating the endometrial biopsy. Fertil Steril 1 (1950) 3-25
16. Pritts E.A., and Atwood A.K. Luteal phase support in infertility treatment: a meta-analysis of the randomized trials. Hum Reprod 17 (2002) 2287-2299
17. Soliman S., Daya S., Collins J., and Hughes E.O. The role of luteal phase support in infertility treatment: a meta-analysis of randomized trials. Fertil Steril 61 (1994) 1068-1076
18. Damario M.A., Goudas V.T., Session D.R., Hammitt D.G., and Dumesic D.A. Crinone 8% vaginal progesterone gel results in lower embryonic implantation efficiency after in vitro fertilization-embryo transfer. Fertil Steril 72 (1999) 830-836
19. Doody KJ, Schnell VL, Foulk R, Miller CE, Kolb BA, Blake EJ, et al. Endometrin for luteal phase support in a randomized, controlled, open-label, prospective in-vitro fertilization trial using a combination of Menopur and Bravelle for controlled ovarian hyperstimulation. Fertil Steril; Published online 25 March, 2008 [Epub ahead of print].
20. Khan N, Ricker KS, Newsome TL, Blake EJ, Yankno VI. Matched-samples comparison of intramuscular versus vaginal progesterone for luteal phase support after in vitro fertilization and embryo transfer. Fertil Steril. Published online 13 June 2008 [Epub ahead of print].