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Volumn 37, Issue 6, 2009, Pages 193-201
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The efficacy of new colchicine derivatives and viability of the T-Lymphoblastoid cells in three-dimensional culture using 19F MRI and HPLC-UV ex vivo
a,b
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Author keywords
19F Magnetic resonance imaging; Colchicine; High performance liquid chromatography coupled with Ultra Violet; Human T Lymphoblastoid; Three dimensional culture
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Indexed keywords
COLCHICINE DERIVATIVE;
FLUORINE DERIVATIVE;
N [(7) 1 (((METHYL)ETHYL)CARBONYLOXY) 2,3,10 TRIMETHOXY 9 OXO 5,6,7,9 TETRAHYDROBENZO[ALPHA]HEPTALEN 7 YL]ACETAMIDE;
N [(7) 1 (ETHOXY) 1 METHYL 2,3,10 TRIMETHOXY 9 OXO 5,6,7,9 TETRAHYDROBENZO[ALPHA]HEPTALEN 7 YL]ACETAMIDE;
N [(7) 1 (ETHOXY) 2,3,10 TRIMETHOXY 9 OXO 5,6,7,9 TETRAHYDROBENZO[ALPHA]HEPTALEN 7 YL]ACETAMIDE;
N [(7) 1 (ETHYL)CARBONYLOXY) 2,3,10 TRIMETHOXY 9 OXO 5,6,7,9 TETRAHYDROBENZO[ALPHA]HEPTALEN 7 YL]ACETAMIDE;
N [(7) 1 HYDROXY2,3,10 TRIMETHOXY 9 OXO 5,6,7,9 TETRAHYDROBENZO[ALPHA]HEPTALEN 7 YL]ACETAMIDE;
N [(7) 2,3,10 TRIMETHOXY 1 ((METHYL)CARBONYLOXY) 9 OXO 5,6,7,9 TETRAHYDROBENZO[A]HEPTALEN 7 YL]ACETAMIDE;
N [(7) 2,3,10 TRIMETHOXY 1 ((METHYL)CYCLOHEXANE) 9 OXO 5,6,7,9 TETRAHYDROBENZO[ALPHA]HEPTALEN 7 YL]ACETAMIDE;
N [(7) 2,3,10 TRIMETHOXY 9 OXO 1 (((3 METHOXY)PROPANE)OXY)(3 METHOXY) 5,6,7,9 TETRAHYDROBENZO[ALPHA]HEPTALEN 7 YL]ACETAMIDE;
N [(7) 2,3,10 TRIMETHOXY 9 OXO 1 (((PHENYL(4 CHLORO))METHOXY) 5,6,7,9 TETRAHYDROBENZO[A]HEPTALEN 7 YL]ACETAMIDE;
N [(7) 2,3,10 TRIMETHOXY 9 OXO 1 ((PHENYL 3 CHLORO))METHOXY) 5,6,7,9 TETRAHYDROBENZO[ALPHA]HEPTALEN 7 YL]ACETAMIDE;
N [(7) 2,3,10 TRIMETHOXY 9 OXO 1 ((PHENYL(2 CHLORO))METHOXY) 5,6,7,9 TETRAHYDROBENZO[ALPHA]HEPTALEN 7 YL]ACETAMIDE;
N [(7) 2,3,10 TRIMETHOXY 9 OXO 1 ((PHENYL)METHOXY) 5,6,7,9 TETRAHYDROBENZO[ALPHA]HEPTALEN 7 YL]ACETAMIDE;
N [(7) 2,3,10 TRIMETHOXY 9 OXO 1 ((PROP(2 EN)OXY) 5,6,7,9 TETRAHYDROBENZO[ALPHA]HEPTALEN 7 YL]ACETAMIDE;
N [(7) 2,3,10 TRIMETHOXY 9 OXO 1 ((PYRIDINE(3))YL) 5,6,7,9 TETRAHYDROBENZO[ALPHA]HEPTALEN 7 YL]ACETAMIDE;
N [(7) 2,3,10 TRIMETHOXY 9 OXO 1 (PROPANOXY) 5,6,7,9 TETRAHYDROBENZO[ALPHA]HEPTALEN 7 YL]ACETAMIDE;
UNCLASSIFIED DRUG;
ARTICLE;
BIOREACTOR;
CELL GROWTH;
CELL VIABILITY;
CONTROLLED STUDY;
DRUG EFFICACY;
DRUG STRUCTURE;
DRUG SYNTHESIS;
EX VIVO STUDY;
FLUORINE NUCLEAR MAGNETIC RESONANCE;
HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;
HUMAN;
HUMAN CELL;
LYMPHOBLASTOID CELL;
LYMPHOBLASTOID CELL LINE;
MONITORING;
PRIORITY JOURNAL;
PROTON NUCLEAR MAGNETIC RESONANCE;
SUBSTITUTION REACTION;
T LYMPHOBLAST;
THREE DIMENSIONAL IMAGING;
ULTRAVIOLET RADIATION;
BIOREACTORS;
CELL CULTURE TECHNIQUES;
CELL SURVIVAL;
CHROMATOGRAPHY, HIGH PRESSURE LIQUID;
COLCHICINE;
FLUORINE;
HUMANS;
MAGNETIC RESONANCE IMAGING;
SPECTROPHOTOMETRY, ULTRAVIOLET;
T-LYMPHOCYTES;
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EID: 70350570376
PISSN: 00452068
EISSN: 10902120
Source Type: Journal
DOI: 10.1016/j.bioorg.2009.07.007 Document Type: Article |
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Times cited : (12)
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References (14)
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