The anti-inflammatory effect of tussilagone, from Tussilago farfara, is mediated by the induction of heme oxygenase-1 in murine macrophages

International Immunopharmacology

Volumn 9, Issue 13-14, 2009, Pages 1578-1584

  Hwangbo, Cheol ^a   Lee, Hyun Sun ^b   Park, Juhee ^a   Choe, Jongseon ^a   Lee, Jeong Hyung ^a  

^a Kangwon National University   (South Korea)

^b Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

Author keywords

Anti inflammatory effects; Heme oxygenase 1; Macrophages; Tussilagone

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; CYCLOHEXIMIDE; CYCLOOXYGENASE 2; DACTINOMYCIN; HEME OXYGENASE 1; INDUCIBLE NITRIC OXIDE SYNTHASE; LIPOPOLYSACCHARIDE; MESSENGER RNA; NITRIC OXIDE; PROSTAGLANDIN E; PROTOPORPHYRIN ZINC; SESQUITERPENOID; TUMOR NECROSIS FACTOR ALPHA; TUSSILAGONE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; ENZYME INHIBITION; GENE EXPRESSION; MACROPHAGE; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS INHIBITION; PROTEIN EXPRESSION; PROTEIN SYNTHESIS INHIBITION; TIME; TUSSILAGO; TUSSILAGO FARFARA; UPREGULATION;

ANIMALS; CELL LINE; CYCLOHEXIMIDE; DACTINOMYCIN; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FEMALE; HEME OXYGENASE-1; MACROPHAGE ACTIVATION; MACROPHAGES, PERITONEAL; MICE; MICE, INBRED BALB C; NUCLEIC ACID SYNTHESIS INHIBITORS; PROTEIN KINASE INHIBITORS; PROTEIN SYNTHESIS INHIBITORS; PROTOPORPHYRINS; RNA, MESSENGER; SESQUITERPENES; TUSSILAGO;

EID: 70350568184     PISSN: 15675769     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.intimp.2009.09.016     Document Type: Article

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