-
2
-
-
0141688377
-
Phase III trial of carboplatin and paclitaxel compared with cisplatin and paclitaxel in patients with optimally resected stage III ovarian cancer: a gynecologic oncology group study
-
Ozols R.F., Bundy B.N., Greer B.E., Fowler J.M., Clarke-Pearson D., Burger R.A., et al. Phase III trial of carboplatin and paclitaxel compared with cisplatin and paclitaxel in patients with optimally resected stage III ovarian cancer: a gynecologic oncology group study. J. Clin. Oncol. 21 17 (2003) 3194-3200
-
(2003)
J. Clin. Oncol.
, vol.21
, Issue.17
, pp. 3194-3200
-
-
Ozols, R.F.1
Bundy, B.N.2
Greer, B.E.3
Fowler, J.M.4
Clarke-Pearson, D.5
Burger, R.A.6
-
3
-
-
63049115790
-
Evaluation of new platinum-based treatment regimens in advanced-stage ovarian cancer: a phase III trial of the Gynecologic Cancer Intergroup
-
Bookman M.A., Brady M.F., McGuire W.P., Harper P.G., Alberts D.S., Friedlander M., et al. Evaluation of new platinum-based treatment regimens in advanced-stage ovarian cancer: a phase III trial of the Gynecologic Cancer Intergroup. J. Clin. Oncol. 27 9 (2009) 1355-1358
-
(2009)
J. Clin. Oncol.
, vol.27
, Issue.9
, pp. 1355-1358
-
-
Bookman, M.A.1
Brady, M.F.2
McGuire, W.P.3
Harper, P.G.4
Alberts, D.S.5
Friedlander, M.6
-
4
-
-
0027944206
-
p53 status and the efficacy of cancer therapy in vivo
-
Lowe S.W., Bodis S., McClatchey A., Remington L., Ruley H.E., Fisher D.E., et al. p53 status and the efficacy of cancer therapy in vivo. Science 266 (1994) 807-810
-
(1994)
Science
, vol.266
, pp. 807-810
-
-
Lowe, S.W.1
Bodis, S.2
McClatchey, A.3
Remington, L.4
Ruley, H.E.5
Fisher, D.E.6
-
5
-
-
8844263797
-
Targeting apoptosis pathways in cancer therapy
-
Fulda S., and Debatin K.M. Targeting apoptosis pathways in cancer therapy. Curr. Cancer Drug Targets 4 7 (2004 Nov) 569-576
-
(2004)
Curr. Cancer Drug Targets
, vol.4
, Issue.7
, pp. 569-576
-
-
Fulda, S.1
Debatin, K.M.2
-
6
-
-
33746886979
-
Extrinsic versus intrinsic apoptosis pathways in anticancer chemotherapy
-
Fulda S., and Debatin K.M. Extrinsic versus intrinsic apoptosis pathways in anticancer chemotherapy. Oncogene 25 34 (2006 Aug 7) 4798-4811
-
(2006)
Oncogene
, vol.25
, Issue.34
, pp. 4798-4811
-
-
Fulda, S.1
Debatin, K.M.2
-
7
-
-
0141431027
-
Tumour necrosis factor alpha: a potential target for the therapy of solid tumours
-
Szlosarek P.W., and Balkwill F.R. Tumour necrosis factor alpha: a potential target for the therapy of solid tumours. Lancet Oncol. 4 9 (2003 Sep) 565-573
-
(2003)
Lancet Oncol.
, vol.4
, Issue.9
, pp. 565-573
-
-
Szlosarek, P.W.1
Balkwill, F.R.2
-
8
-
-
0034896632
-
Role of tumor necrosis factor on toxicity and cytokine production after isolated hepatic perfusion1
-
Titia E., Lans D.L.B., Libutti S.K., Gnant M.F.X., Liewehr D.J., Venzon D.J., et al. Role of tumor necrosis factor on toxicity and cytokine production after isolated hepatic perfusion1. Clin. Cancer Res. 7 (2001, April) 784-790
-
(2001)
Clin. Cancer Res.
, vol.7
, pp. 784-790
-
-
Titia, E.1
Lans, D.L.B.2
Libutti, S.K.3
Gnant, M.F.X.4
Liewehr, D.J.5
Venzon, D.J.6
-
9
-
-
36048982462
-
Smac mimetics and TNFa: a dangerous liaison?
-
Hao Wu J.T., and Lin S.C. Smac mimetics and TNFa: a dangerous liaison?. Cell 131 (2007, November 16) 655-658
-
(2007)
Cell
, vol.131
, pp. 655-658
-
-
Hao Wu, J.T.1
Lin, S.C.2
-
10
-
-
0032713075
-
Safety and antitumor activity of recombinant soluble Apo2 ligand
-
Ashkenazi A., Pai R.C., Fong S., Leung S., Lawrence D.A., Marsters S.A., et al. Safety and antitumor activity of recombinant soluble Apo2 ligand. J. Clin. Invest. 104 (1999) 155-162
-
(1999)
J. Clin. Invest.
, vol.104
, pp. 155-162
-
-
Ashkenazi, A.1
Pai, R.C.2
Fong, S.3
Leung, S.4
Lawrence, D.A.5
Marsters, S.A.6
-
11
-
-
34249663310
-
Targeting death-inducing receptors in cancer therapy
-
Takeda K., Stagg J., Yagita H., Okumura K., and Smyth M.J. Targeting death-inducing receptors in cancer therapy. Oncogene 26 (2007) 3745-3757
-
(2007)
Oncogene
, vol.26
, pp. 3745-3757
-
-
Takeda, K.1
Stagg, J.2
Yagita, H.3
Okumura, K.4
Smyth, M.J.5
-
12
-
-
51449118394
-
Targeting TRAIL death receptors
-
Oldenhuis C.N.A.M., Stegehuis J.H., Walenkamp A.M.E., de Jong S., and de Vries E.G.E. Targeting TRAIL death receptors. Curr. Opin. Pharmacol. 8 4 (2008, Aug) 433-439
-
(2008)
Curr. Opin. Pharmacol.
, vol.8
, Issue.4
, pp. 433-439
-
-
Oldenhuis, C.N.A.M.1
Stegehuis, J.H.2
Walenkamp, A.M.E.3
de Jong, S.4
de Vries, E.G.E.5
-
13
-
-
52649109068
-
The TRAIL apoptotic pathway in cancer onset, progression and therapy
-
Johnstone R.W., Frew A.J., and Smyth M.J. The TRAIL apoptotic pathway in cancer onset, progression and therapy. Nat. Rev., Cancer 8 (2008) 782-798
-
(2008)
Nat. Rev., Cancer
, vol.8
, pp. 782-798
-
-
Johnstone, R.W.1
Frew, A.J.2
Smyth, M.J.3
-
14
-
-
37449023100
-
Death receptor expression is associated with poor response to chemotherapy and shorter survival in metastatic ovarian cancer
-
Dong H.P., Kleinberg L., Silins I., Florenes V.A., Trope C.G., Risberg B., et al. Death receptor expression is associated with poor response to chemotherapy and shorter survival in metastatic ovarian cancer. Cancer 112 (2008) 84-93
-
(2008)
Cancer
, vol.112
, pp. 84-93
-
-
Dong, H.P.1
Kleinberg, L.2
Silins, I.3
Florenes, V.A.4
Trope, C.G.5
Risberg, B.6
-
15
-
-
23844454988
-
Flexible heteroarotinoids (Flex-Hets) exhibit improved therapeutic ratios as anti-cancer agents over retinoic acid receptor antagonists
-
Benbrook D.M., Kamelle S.A., Guruswamy S.B., Lightfoot S.A., Hannafon B., Rutledge T.L., et al. Flexible heteroarotinoids (Flex-Hets) exhibit improved therapeutic ratios as anti-cancer agents over retinoic acid receptor antagonists. Inv. New Drugs 23 (2005) 417-428
-
(2005)
Inv. New Drugs
, vol.23
, pp. 417-428
-
-
Benbrook, D.M.1
Kamelle, S.A.2
Guruswamy, S.B.3
Lightfoot, S.A.4
Hannafon, B.5
Rutledge, T.L.6
-
16
-
-
66849092433
-
Gene expression analysis of biological systems driving an organotypic model of endometrial carcinogenesis and chemoprevention
-
Benbrook D.M., Lightfoot S., Ranger-Moore J., Liu T., Chengedza S., Berry W.L., et al. Gene expression analysis of biological systems driving an organotypic model of endometrial carcinogenesis and chemoprevention. Gene Regul. Syst. Biol. 2 (2008) 21-42
-
(2008)
Gene Regul. Syst. Biol.
, vol.2
, pp. 21-42
-
-
Benbrook, D.M.1
Lightfoot, S.2
Ranger-Moore, J.3
Liu, T.4
Chengedza, S.5
Berry, W.L.6
-
17
-
-
0035804648
-
Effects of retinoids on cancerous phenotype and apoptosis in organotypic culture of ovarian carcinoma
-
Guruswamy S., Lightfoot S., Gold M., Hassan R., Berlin K.D., Ivey R.T., et al. Effects of retinoids on cancerous phenotype and apoptosis in organotypic culture of ovarian carcinoma. J. Nat. Cancer Inst. 93 (2001) 516-525
-
(2001)
J. Nat. Cancer Inst.
, vol.93
, pp. 516-525
-
-
Guruswamy, S.1
Lightfoot, S.2
Gold, M.3
Hassan, R.4
Berlin, K.D.5
Ivey, R.T.6
-
18
-
-
67651181068
-
-
Myers T, Chengedza S, Lightfoot S, Pan Y, Dedmond D, Cole L, et al. Flexible Heteroarotinoid (Flex-Het) SHetA2 inhibits angiogenesis in vitro and in vivo. Investigational New Drugs. 2008: published online: 18 September.
-
Myers T, Chengedza S, Lightfoot S, Pan Y, Dedmond D, Cole L, et al. Flexible Heteroarotinoid (Flex-Het) SHetA2 inhibits angiogenesis in vitro and in vivo. Investigational New Drugs. 2008: published online: 18 September.
-
-
-
-
19
-
-
66849124550
-
Development of flexible-heteroarotinoids (Flex-Hets) for kidney cancer
-
Liu T., Masamha P., Chengedza S., Berlin K.D., Lightfoot S., He F., et al. Development of flexible-heteroarotinoids (Flex-Hets) for kidney cancer. Mol. Cancer Ther. 8 5 (2009) 1227-1238
-
(2009)
Mol. Cancer Ther.
, vol.8
, Issue.5
, pp. 1227-1238
-
-
Liu, T.1
Masamha, P.2
Chengedza, S.3
Berlin, K.D.4
Lightfoot, S.5
He, F.6
-
20
-
-
34250760931
-
Flex-Hets differentially induce apoptosis in cancer over normal cells by directly targeting mitochondria
-
Liu T.Z., Hannafon B., Gill L., Kelly B., and Benbrook D.M. Flex-Hets differentially induce apoptosis in cancer over normal cells by directly targeting mitochondria. Mol. Cancer Ther. 6 (2007) 1814-1822
-
(2007)
Mol. Cancer Ther.
, vol.6
, pp. 1814-1822
-
-
Liu, T.Z.1
Hannafon, B.2
Gill, L.3
Kelly, B.4
Benbrook, D.M.5
-
21
-
-
0842282737
-
Synthesis of flexible sulfur-containing heteroarotinoids that induce apoptosis and reactive oxygen species with discrimination between malignant and benign cells
-
Liu S., Brown C.W., Berlin K.D., Dhar A., Guruswamy S.B., Brown D., et al. Synthesis of flexible sulfur-containing heteroarotinoids that induce apoptosis and reactive oxygen species with discrimination between malignant and benign cells. J. Med. Chem. 47 (2004) 999-1007
-
(2004)
J. Med. Chem.
, vol.47
, pp. 999-1007
-
-
Liu, S.1
Brown, C.W.2
Berlin, K.D.3
Dhar, A.4
Guruswamy, S.B.5
Brown, D.6
-
22
-
-
0036733990
-
Retinoids and steroids regulate menstrual phase histologic features in human endometrial organotypic cultures
-
Kamelle S.A., Sienko A., and Benbrook D.M. Retinoids and steroids regulate menstrual phase histologic features in human endometrial organotypic cultures. Fertil. Steril. 78 3 (2002) 596-602
-
(2002)
Fertil. Steril.
, vol.78
, Issue.3
, pp. 596-602
-
-
Kamelle, S.A.1
Sienko, A.2
Benbrook, D.M.3
-
23
-
-
33746428587
-
Time sequence of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and cisplatin treatment is responsible for a complex pattern of synergistic cytotoxicity
-
Kim Y.H., and Lee Y.J. Time sequence of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and cisplatin treatment is responsible for a complex pattern of synergistic cytotoxicity. J. Cell. Biochem. 98 (2006) 1284-1295
-
(2006)
J. Cell. Biochem.
, vol.98
, pp. 1284-1295
-
-
Kim, Y.H.1
Lee, Y.J.2
-
24
-
-
42149095910
-
NF-kappaB inhibition reveals differential mechanisms of TNF versus TRAIL-induced apoptosis upstream or at the level of caspase-8 activation independent of cIAP2
-
Diessenbacher P., Hupe M., Sprick M.R., Kerstan A., Geserick P., Haas T.L., et al. NF-kappaB inhibition reveals differential mechanisms of TNF versus TRAIL-induced apoptosis upstream or at the level of caspase-8 activation independent of cIAP2. J. Invest. Dermatol. 128 5 (2008 May) 1134-1147
-
(2008)
J. Invest. Dermatol.
, vol.128
, Issue.5
, pp. 1134-1147
-
-
Diessenbacher, P.1
Hupe, M.2
Sprick, M.R.3
Kerstan, A.4
Geserick, P.5
Haas, T.L.6
-
25
-
-
85056040349
-
Heteroarotinoids with anti-cancer activity against ovarian cancer cells
-
Le T.C., Berlin K.D., Benson S.D., Eastman M.A., Bell-Eunice G., Nelson A.C., et al. Heteroarotinoids with anti-cancer activity against ovarian cancer cells. Open. Med. Chem. J. 1 (2007) 11-23
-
(2007)
Open. Med. Chem. J.
, vol.1
, pp. 11-23
-
-
Le, T.C.1
Berlin, K.D.2
Benson, S.D.3
Eastman, M.A.4
Bell-Eunice, G.5
Nelson, A.C.6
-
26
-
-
0037795409
-
Retinoid activation of retinoic acid receptor but not retinoid X receptor is sufficient to rescue lethal defect in retinoic acid synthesis
-
Mic F.A., Molotkov A., Benbrook D.M., and Duester G. Retinoid activation of retinoic acid receptor but not retinoid X receptor is sufficient to rescue lethal defect in retinoic acid synthesis. Proc. Natl. Acad. Sci. U. S. A. 100 (2003) 7135-7140
-
(2003)
Proc. Natl. Acad. Sci. U. S. A.
, vol.100
, pp. 7135-7140
-
-
Mic, F.A.1
Molotkov, A.2
Benbrook, D.M.3
Duester, G.4
-
27
-
-
43749109848
-
Cisplatin enhances the antitumor effect of tumor necrosis factor-related apoptosis-inducing ligand gene therapy via recruitment of the mitochondria-dependent death signaling pathway
-
Shamimi-Noori S., Yeow W.S., Ziauddin M.F., Xin H., Tran T.L.N., XIe J., et al. Cisplatin enhances the antitumor effect of tumor necrosis factor-related apoptosis-inducing ligand gene therapy via recruitment of the mitochondria-dependent death signaling pathway. Cancer Gene Ther. 15 (2008) 356-370
-
(2008)
Cancer Gene Ther.
, vol.15
, pp. 356-370
-
-
Shamimi-Noori, S.1
Yeow, W.S.2
Ziauddin, M.F.3
Xin, H.4
Tran, T.L.N.5
XIe, J.6
-
28
-
-
11844293509
-
Effects of sequential treatments with chemotherapeutic drugs followed by TRAIL on prostate cancer in vitro and in vivo
-
Shanhar S., Chen X., and Srivastava R.K. Effects of sequential treatments with chemotherapeutic drugs followed by TRAIL on prostate cancer in vitro and in vivo. Prostate 62 2 (2005) 165-186
-
(2005)
Prostate
, vol.62
, Issue.2
, pp. 165-186
-
-
Shanhar, S.1
Chen, X.2
Srivastava, R.K.3
-
29
-
-
0141705424
-
Synergistic interactions of chemotherapeutic drugs and tumor necrosis factor-related apoptosis-inducing ligand/Apo-2 ligand on apoptosis and on regression of breast carcinoma in vivo
-
Singh T.R., Shankar S., Chen X., Asim M., and Srivastava R.K. Synergistic interactions of chemotherapeutic drugs and tumor necrosis factor-related apoptosis-inducing ligand/Apo-2 ligand on apoptosis and on regression of breast carcinoma in vivo. Cancer Res. 63 17 (2003) 5390-5400
-
(2003)
Cancer Res.
, vol.63
, Issue.17
, pp. 5390-5400
-
-
Singh, T.R.1
Shankar, S.2
Chen, X.3
Asim, M.4
Srivastava, R.K.5
-
30
-
-
44849106825
-
TRAIL inactivates the mitotic checkpoint and potentiates death induced by microtubule-targeting agents in human cancer cells
-
Kim M., Liao J., Dowling M.L., Voong K.R., Parker S.E., Wang S., et al. TRAIL inactivates the mitotic checkpoint and potentiates death induced by microtubule-targeting agents in human cancer cells. Cancer Res. 68 9 (2008, May 1) 3440-3449
-
(2008)
Cancer Res.
, vol.68
, Issue.9
, pp. 3440-3449
-
-
Kim, M.1
Liao, J.2
Dowling, M.L.3
Voong, K.R.4
Parker, S.E.5
Wang, S.6
-
31
-
-
44849106825
-
TRAIL inactivates the mitotic checkpoint and potentiates death induced by microtubule-targeting agents in human cancer cells
-
Kim M., Liao J.D., Voong M.L., Parker K.R., Wang S.E., El-Deiry S., W.S, et al. TRAIL inactivates the mitotic checkpoint and potentiates death induced by microtubule-targeting agents in human cancer cells. Cancer Res 68 9 (2008) 3440-3449
-
(2008)
Cancer Res
, vol.68
, Issue.9
, pp. 3440-3449
-
-
Kim, M.1
Liao, J.D.2
Voong, M.L.3
Parker, K.R.4
Wang, S.E.5
El-Deiry, S.6
W.S7
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