Regulation of low-density lipoprotein receptor and 3-hydroxy-3- methylglutaryl coenzyme a reductase gene expression by thymoquinone-rich fraction and thymoquinone in HepG2 cells

Journal of Nutrigenetics and Nutrigenomics

Volumn 2, Issue 4-5, 2010, Pages 163-172

  Al Naqeep, Ghanya ^a,b   Ismail, Maznah ^a,b   Allaudin, Zeenathul ^c  

^a Institute of Bioscience   (Malaysia)

^b Universiti Putra Malaysia   (Malaysia)

^c UNIVERSITY PUTRA MALAYSIA   (Malaysia)

Author keywords

25 Hydroxycholesterol; 3 Hydroxy 3 methyl glutaryl coenzyme A reductase; HepG2 cells; Low density lipoprotein receptor; Nigella sativa; Supercritical fluid extraction; Thymoquinone; Thymoquinone rich fraction

Indexed keywords

CHOLESTEROL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; LOW DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN RECEPTOR; MESSENGER RNA; THYMOQUINONE; THYMOQUINONE RICH FRACTION; UNCLASSIFIED DRUG;

ARTICLE; BLACK CUMIN; CELL STRAIN HEPG2; CHOLESTEROL METABOLISM; CHOLESTEROL SYNTHESIS; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; EXTRACTION; GENE EXPRESSION REGULATION; GENE REPRESSION; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; RECEPTOR DOWN REGULATION; RECEPTOR UPREGULATION;

BENZOQUINONES; CELL SURVIVAL; DNA, COMPLEMENTARY; DNA, NEOPLASM; FLOW CYTOMETRY; GENE EXPRESSION REGULATION, NEOPLASTIC; HEP G2 CELLS; HUMANS; HYDROXYMETHYLGLUTARYL COA REDUCTASES; NIGELLA SATIVA; POLYMERASE CHAIN REACTION; RECEPTORS, LDL; RNA, MESSENGER; RNA, NEOPLASM;

NIGELLA SATIVA;

EID: 70350553971     PISSN: 16616499     EISSN: 16616758     Source Type: Journal    
DOI: 10.1159/000227264     Document Type: Article

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