Susceptibility to Crohn's disease is mediated by KIR2DL2/KIR2DL3 heterozygosity and the HLA-C ligand

Immunogenetics

Volumn 61, Issue 10, 2009, Pages 663-671

  Hollenbach, Jill A ^a   Ladner, Martha B ^a   Saeteurn, Koy ^a   Taylor, Kent D ^b   Mei, Ling ^b   Haritunians, Talin ^b   McGovern, Dermot P B ^b   Erlich, Henry A ^c   Rotter, Jerome I ^b   Trachtenberg, Elizabeth A ^a  

^a CHILDREN S HOSPITAL OAKLAND RESEARCH INSTITUTE   (United States)

^b CEDARS SINAI MEDICAL CENTER   (United States)

^c ROCHE MOLECULAR SYSTEMS   (United States)

Author keywords

Crohn's disease; Heterozygosity; HLA; KIR; Ligand

Indexed keywords

HLA ANTIGEN CLASS 1; HLA C ANTIGEN; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR 2DL1; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR 2DL2; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR 2DL3;

ARTICLE; CONTROLLED STUDY; CROHN DISEASE; DISEASE PREDISPOSITION; GENE FREQUENCY; GENE INTERACTION; GENE LOCUS; GENETIC SUSCEPTIBILITY; GENOTYPE; HETEROZYGOSITY; HOMOZYGOSITY; HUMAN; MAJOR CLINICAL STUDY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; PRIORITY JOURNAL; SEQUENCE ANALYSIS;

ADULT; ALLELES; CALIFORNIA; CASE-CONTROL STUDIES; COHORT STUDIES; CROHN DISEASE; EUROPEAN CONTINENTAL ANCESTRY GROUP; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HETEROZYGOTE; HLA-C ANTIGENS; HUMANS; JEWS; LIGANDS; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTORS, KIR2DL2; RECEPTORS, KIR2DL3; SINGLE-BLIND METHOD; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

EID: 70350542586     PISSN: 00937711     EISSN: 14321211     Source Type: Journal    
DOI: 10.1007/s00251-009-0396-5     Document Type: Article

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