Linkage analysis of candidate genes in families with vesicoureteral reflux

Journal of Urology

Volumn 182, Issue 4 SUPPL., 2009, Pages 1669-1672

  Kelly, Helena ^a   Barton, David ^a   Molony, Cliona ^d   Puri, Prem ^a,b,c  

^a OUR LADY S CHILDREN S HOSPITAL   (Ireland)

^b ADELAIDE AND MEATH HOSPITAL   (Ireland)

^c UNIVERSITY COLLEGE DUBLIN   (Ireland)

^d ROSETTA INPHARMATICS   (United States)

Author keywords

Linkage (genetics); Siblings; Ureter; Urinary bladder; Vesico ureteral reflux

Indexed keywords

ARTICLE; GENETIC LINKAGE; GENETICS; HUMAN; VESICOURETERAL REFLUX;

HUMANS; LINKAGE (GENETICS); VESICO-URETERAL REFLUX;

EID: 70350519356     PISSN: 00225347     EISSN: 15273792     Source Type: Journal    
DOI: 10.1016/j.juro.2009.03.013     Document Type: Conference Paper

References (20)

1. Smellie JM, Barratt TM, Chantler C et al: Medical versus surgical treatment in children with severe bilateral vesicoureteric reflux and bilateral nephropathy: a randomised trial. Lancet 2001; 357: 1329.
2. Hoberman A, Charron M, Hickey RW et al: Imaging studies after a first febrile urinary tract infection in young children. N Engl J Med 2003; 348: 195.
3. Marra G, Oppezo C, Ardission G et al: Severe vesicoureteral reflux and chronic renal failure: a condition peculiar to male gender? Data from the Italkid Project J Pediatr 2004; 144: 677.
4. Noe HN: The long-term results of prospective sibling reflux screening. J Urol 1992; 148: 1739.
5. Parekh DJ, Pope JCT, Adams MC et al: Outcome of sibling vesicoureteral reflux. J Urol 2002; 167: 283.
6. Chertin B and Puri P: Familial vesicoureteral reflux. J Urol 2003; 169: 1804.
7. Hu P, Deng FM, Liang FX et al: Ablation of uroplakin III gene results in small urothelial plaques, urothelial leakage, and vesicoureteral reflux. J Cell Biol 2000; 151: 961.
8. Lu W, van Eerde AM, Fan X et al: Disruption of ROBO2 is associated with urinary tract anomalies and confers risk of vesicoureteral reflux. Am J Hum Genet 2007; 80: 616.
9. Koolen DA, Herbergs J, Veltman JA et al: Holoprosencephaly and preaxial polydactyly associated with a 1.24 Mb duplication encompassing FBXW11 at 5q35.1. J Hum Genet 2006; 51: 721.
10. Ogata T, Muroya K, Sasagawa I et al: Genetic evidence for a novel gene(s) involved in urogenital development on 10q26. Kidney Int 2000; 58: 2281.
11. Feather SA, Malcolm S, Woolf AS et al: Primary, nonsyndromic vesicoureteric reflux and its nephropathy is genetically heterogeneous, with a locus on chromosome 1. Am J Hum Genet 2000; 66: 1420.
12. Kelly H, Molony CM, Darlow JM et al: A genomewide scan for genes involved in primary vesi-coureteric reflux. J Med Genet 2007; 44: 710.
13. Conte ML, Bertoli-Avella AM, de Graaf BM et al: A genome search for primary vesicoureteral reflux shows further evidence for genetic heterogeneity. Pediatr Nephrol 2008; 23: 587.
14. Pirker ME, Mohanan N, Colhoun E et al: Familial vesicoureteral reflux: influence of sex on prevalence and expression. J Urol 2006; 176: 1776.
15. Kruglyak L, Daly MJ, Reeve-Daly MP et al: Parametric and nonparametric linkage analysis: a unified multipoint approach. Am J Hum Genet 1996; 58: 1347.
16. Chapman CJ, Bailey RR, Janus ED et al: Vesi-coureteric reflux: segregation analysis. Am J Med Genet 1985; 20: 577.
17. Kelly H, Ennis S, Yoneda A et al: Uroplakin III is not a major candidate gene for primary vesi-coureteral reflux. Eur J Hum Genet 2005; 13: 500.
18. Giltay JC, van de Meerakker J, van Amstel HK et al: No pathogenic mutations in the uroplakin III gene of 25 patients with primary vesicoureteral reflux. J Urol 2004; 171: 931.
19. Jiang S, Gitlin J, Deng FM et al: Lack of major involvement of human uroplakin genes in vesi-coureteral reflux: implications for disease heterogeneity. Kidney Int 2004; 66: 10.
20. Yoneda A, Cascio S, Green A et al: Angiotensin II type 2 receptor gene is not responsible for familial vesicoureteral reflux. J Urol 2002; 168: 1138.