Characterization of the herpes simplex virus (HSV)-1 tegument protein VP1-2 during infection with the HSV temperature-sensitive mutant tsB7

Journal of General Virology

Volumn 90, Issue 10, 2009, Pages 2353-2363

  Abaitua, F ^a   Souto, R N ^b,c   Browne, H ^b   Daikoku, T ^a,d   O'Hare, P ^a  

^a MARIE CURIE RESEARCH INSTITUTE   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c UNIVERSITY OF PORTO   (Portugal)

^d UNIVERSITY OF TOYAMA   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

GREEN FLUORESCENT PROTEIN; PROTEIN VP1; PROTEIN VP16; PROTEIN VP2; RECOMBINANT PROTEIN; VIRUS PROTEIN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOSOL; ELECTRON MICROSCOPY; GENE CLUSTER; HERPES SIMPLEX; HERPES SIMPLEX VIRUS 1; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN LOCALIZATION; TEMPERATURE SENSITIVITY; UBIQUITINATION; VIRION; VIRUS MUTANT; VIRUS REPLICATION; ANIMAL; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MUTATION; PHYSIOLOGY; PROTEIN TRANSPORT; TEMPERATURE; TUMOR CELL LINE;

HERPESVIRIDAE; HUMAN HERPESVIRUS 1; MIRIDAE; SIMPLEXVIRUS;

ANIMALS; CELL LINE, TUMOR; GENE EXPRESSION REGULATION, VIRAL; GREEN FLUORESCENT PROTEINS; HERPESVIRUS 1, HUMAN; HUMANS; MUTATION; PROTEIN TRANSPORT; RECOMBINANT PROTEINS; TEMPERATURE; VIRAL PROTEINS;

EID: 70350516473     PISSN: 00221317     EISSN: 14652099     Source Type: Journal    
DOI: 10.1099/vir.0.012492-0     Document Type: Article

References (37)

1. Abaitua, F. & O'Hare, P. (2008). Identification of a highly conserved, functional nuclear localization signal within the N-terminal region of herpes simplex virus type 1 VP1-2 tegument protein. J Virol 82, 5234-5244.
2. Batterson, W. & Roizman, B. (1983). Characterization of the herpes simplex virion-associated factor responsible for the induction of alpha genes. J Virol 46, 371-377.
3. Batterson, W., Furlong, D. & Roizman, B. (1983). Molecular genetics of herpes simplex virus. VIII. Further characterization of a temperature-sensitive mutant defective in release of viral DNA and in other stages of the viral reproductive cycle. J Virol 45, 397-407.
4. Bottcher, S., Maresch, C., Granzow, H., Klupp, B. G., Teifke, J. P. & Mettenleiter, T. C. (2008). Mutagenesis of the active-site cysteine in the ubiquitin-specific protease contained in large tegument protein pUL36 of pseudorabies virus impairs viral replication in vitro and neuroinvasion in vivo. J Virol 82, 6009-6016.
5. Bucks, M. A., O'Regan, K. J., Murphy, M. A., Wills, J. W. & Courtney, R. J. (2007). Herpes simplex virus type 1 tegument proteins VP1/2 and UL37 are associated with intranuclear capsids. Virology 361, 316-324.
6. Burch, A. D. & Weller, S. K. (2004). Nuclear sequestration of cellular chaperone and proteasomal machinery during herpes simplex virus type 1 infection. J Virol 78, 7175-7185.
7. Calistri, A., Sette, P., Salata, C., Cancellotti, E., Forghieri, C., Comin, A., Gottlinger, H., Campadelli-Fiume, G., Palu, G. & Parolin, C. (2007). Intracellular trafficking and maturation of herpes simplex virus type 1 gB and virus egress require functional biogenesis of multivesicular bodies. J Virol 81, 11468-11478.
8. Crump, C. M., Yates, C. & Minson, T. (2007). Herpes simplex virus type 1 cytoplasmic envelopment requires functional Vps4. J Virol 81, 7380-7387.
9. Desai, P. J. (2000). A null mutation in the UL36 gene of herpes simplex virus type 1 results in accumulation of unenveloped DNA-filled capsids in the cytoplasm of infected cells. J Virol 74, 11608-11618.
10. Desai, P., Sexton, G. L., McCaffery, J. M. & Person, S. (2001). A null mutation in the gene encoding the herpes simplex virus type 1 UL37 polypeptide abrogates virus maturation. J Virol 75, 10259-10271.
11. Fuchs, W., Klupp, B. G., Granzow, H. & Mettenleiter, T. C. (2004). Essential function of the pseudorabies virus UL36 gene product is independent of its interaction with the UL37 protein. J Virol 78, 11879-11889.
12. Fujimuro, M., Sawada, H. & Yokosawa, H. (1994). Production and characterization of monoclonal antibodies specific to multi-ubiquitin chains of polyubiquitinated proteins. FEBS Lett 349, 173-180.
13. Gibson, W. & Roizman, B. (1972). Proteins specified by herpes simplex virus. VIII. Characterization and composition of multiple capsid forms of subtypes 1 and 2. J Virol 10, 1044-1052.
14. Granzow, H., Klupp, B. G. & Mettenleiter, T. C. (2005). Entry of pseudorabies virus: an immunogold-labeling study. J Virol 79, 3200-3205.
15. Heine, J. W., Honess, R. W., Cassai, E. & Roizman, B. (1974). Proteins specified by herpes simplex virus. XII. The virion polypeptides of type 1 strains. J Virol 14, 640-651.
16. Jarosinski, K., Kattenhorn, L., Kaufer, B., Ploegh, H. & Osterrieder, N. (2007). A herpesvirus ubiquitin-specific protease is critical for efficient T cell lymphoma formation. Proc Natl Acad Sci U S A 104, 20025-20030.
17. Jovasevic, V., Liang, L. & Roizman, B. (2008). Proteolytic cleavage of VP1-2 is required for release of herpes simplex virus 1 DNA into the nucleus. J Virol 82, 3311-3319.
18. Klupp, B. G., Granzow, H., Mundt, E. & Mettenleiter, T. C. (2001). Pseudorabies virus UL37 gene product is involved in secondary envelopment. J Virol 75, 8927-8936.
19. Klupp, B. G., Fuchs, W., Granzow, H., Nixdorf, R. & Mettenleiter, T. C. (2002). Pseudorabies virus UL36 tegument protein physically interacts with the UL37 protein. J Virol 76, 3065-3071.
20. Knipe, D. M., Batterson, W., Nosal, C., Roizman, B. & Buchan, A. (1981). Molecular genetics of herpes simplex virus. VI. Characterization of a temperature-sensitive mutant defective in the expression of all early viral gene products. J Virol 38, 539-547.
21. La Boissiere, S., Izeta, A., Malcomber, S. & O'Hare, P. (2004). Compartmentalization of VP16 in cells infected with recombinant herpes simplex virus expressing VP16-green fluorescent protein fusion proteins. J Virol 78, 8002-8014.
22. Lee, J. I., Luxton, G. W. & Smith, G. A. (2006). Identification of an essential domain in the herpesvirus VP1/2 tegument protein: the carboxy terminus directs incorporation into capsid assemblons. J Virol 80, 12086-12094.
23. Leege, T., Granzow, H., Fuchs, W., Klupp, B. & Mettenleiter, T. C. (2009). Phenotypic similarities and differences between UL37-deleted pseudorabies virus and herpes simplex virus type 1. J Gen Virol 90, 1560-1568.
24. Luxton, G. W., Haverlock, S., Coller, K. E., Antinone, S. E., Pincetic, A. & Smith, G. A. (2005). Targeting of herpesvirus capsid transport in axons is coupled to association with specific sets of tegument proteins. Proc Natl Acad Sci U S A 102, 5832-5837.
25. Luxton, G. W., Lee, J. I., Haverlock-Moyns, S., Schober, J. M. & Smith, G. A. (2006). The pseudorabies virus VP1/2 tegument protein is required for intracellular capsid transport. J Virol 80, 201-209.
26. McLean, C., Buckmaster, A., Hancock, D., Buchan, A., Fuller, A. & Minson, T. (1982). Monoclonal antibodies to three nonglycosylated antigens of herpes simplex virus type 2. J Gen Virol 63, 297-305.
27. McNabb, D. S. & Courtney, R. J. (1992a). Analysis of the UL36 open reading frame encoding the large tegument protein (ICP1/2) of herpes simplex virus type 1. J Virol 66, 7581-7584.
28. McNabb, D. S. & Courtney, R. J. (1992b). Characterization of the large tegument protein (ICP1/2) of herpes simplex virus type 1. Virology 190, 221-232.
29. Mettenleiter, T. C. (2002). Herpesvirus assembly and egress. J Virol 76, 1537-1547.
30. Michael, K., Klupp, B. G., Mettenleiter, T. C. & Karger, A. (2006). Composition of pseudorabies virus particles lacking tegument protein US3, UL47, or UL49 or envelope glycoprotein E. J Virol 80, 1332-1339.
31. Rixon, F. (1993). Stucture and assembly of herpesviruses. Semin Virol 4, 135-144.
32. Roberts, A. P., Abaitua, F., O'Hare, P., McNab, D., Rixon, F. J. & Pasdeloup, D. (2009). Differing roles of inner tegument proteins pUL36 and pUL37 during entry of herpes simplex virus type 1 (HSV-1). J Virol 83, 105-116.
33. Skepper, J. N., Whiteley, A., Browne, H. & Minson, A. (2001). Herpes simplex virus nucleocapsids mature to progeny virions by an envelopment → deenvelopment → reenvelopment pathway. J Virol 75, 5697-5702.
34. Trus, B. L., Newcomb, W. W., Cheng, N., Cardone, G., Marekov, L., Homa, F. L., Brown, J. C. & Steven, A. C. (2007). Allosteric signaling and a nuclear exit strategy: binding of UL25/UL17 heterodimers to DNA-filled HSV-1 capsids. Mol Cell 26, 479-489.
35. Wang, J., Loveland, A. N., Kattenhorn, L. M., Ploegh, H. L. & Gibson, W. (2006). High-molecular-weight protein (pUL48) of human cytomegalovirus is a competent deubiquitinating protease: mutant viruses altered in its active-site cysteine or histidine are viable. J Virol 80, 6003-6012.
36. - mutants of herpes simplex virus 1. Virology 241, 189-199.
37. Zhou, Z.-H., Chen, D. H., Jakana, J., Rixon, F. J. & Chiu, W. (1999). Visualization of tegument-capsid interactions and DNA in intact herpes simplex virus type 1 virions. J Virol 73, 3210-3218.