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Volumn 5, Issue 9, 2009, Pages 480-482

Genetics: Mutations in the IL1RN locus lead to autoinflammation

Author keywords

[No Author keywords available]

Indexed keywords

IL1RN PROTEIN, HUMAN; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT;

EID: 70350512821     PISSN: 17594790     EISSN: 17594804     Source Type: Journal    
DOI: 10.1038/nrrheum.2009.177     Document Type: Article
Times cited : (11)

References (10)
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    • An autoinflammatory disease with deficiency of the interleukin-1-receptor antagonist
    • Aksentijevich, I. et al. An autoinflammatory disease with deficiency of the interleukin-1-receptor antagonist. N. Engl. J. Med. 360, 2426–2437 (2009).
    • (2009) N. Engl. J. Med. , vol.360 , pp. 2426-2437
    • Aksentijevich, I.1
  • 2
    • 66649113371 scopus 로고    scopus 로고
    • An autoinflammatory disease due to homozygous deletion of the IL1RN locus
    • Reddy, S. et al. An autoinflammatory disease due to homozygous deletion of the IL1RN locus. N. Engl. J. Med. 360, 2438–2444 (2009).
    • (2009) N. Engl. J. Med. , vol.360 , pp. 2438-2444
    • Reddy, S.1
  • 3
    • 0034677123 scopus 로고    scopus 로고
    • Development of chronic inflammatory arthropathy resembling rheumatoid arthritis in interleukin 1 receptor antagonist-deficient mice
    • Horai, R. et al. Development of chronic inflammatory arthropathy resembling rheumatoid arthritis in interleukin 1 receptor antagonist-deficient mice. J. Exp. Med. 191, 313–320 (2000).
    • (2000) J. Exp. Med. , vol.191 , pp. 313-320
    • Horai, R.1
  • 4
    • 0034677174 scopus 로고    scopus 로고
    • Arterial inflammation in mice lacking the interleukin 1 receptor antagonist gene
    • Nicklin, M. J., Hughes, D. E., Barton, J. L., Ure, J. M. & Duff, G. W. Arterial inflammation in mice lacking the interleukin 1 receptor antagonist gene. J. Exp. Med. 191, 303–312 (2000).
    • (2000) J. Exp. Med. , vol.191 , pp. 303-312
    • Nicklin, M.J.1    Hughes, D.E.2    Barton, J.L.3    Ure, J.M.4    Duff, G.W.5
  • 5
    • 34447545616 scopus 로고    scopus 로고
    • Type i iL-1 receptor mediates iL-1 and intracellular iL-1 receptor antagonist effects in skin inflammation
    • Palmer, G., Talabot-Ayer, D., Kaya, G. & Gabay, C. Type i iL-1 receptor mediates iL-1 and intracellular iL-1 receptor antagonist effects in skin inflammation. J. Invest. Dermatol. 127, 1938–1946 (2007).
    • (2007) J. Invest. Dermatol. , vol.127 , pp. 1938-1946
    • Palmer, G.1    Talabot-Ayer, D.2    Kaya, G.3    Gabay, C.4
  • 6
    • 38149048556 scopus 로고    scopus 로고
    • Stimulation of TLR2 and TLR4 differentially skews the balance of T cells in a mouse model of arthritis
    • Abdollahi-Roodsaz, S. et al. Stimulation of TLR2 and TLR4 differentially skews the balance of T cells in a mouse model of arthritis. J. Clin. Invest. 118, 205–216 (2008).
    • (2008) J. Clin. Invest. , vol.118 , pp. 205-216
    • Abdollahi-Roodsaz, S.1
  • 7
    • 84984761883 scopus 로고    scopus 로고
    • Myeloid-cell specific interleukin-1 receptor antagonist deficiency enhances TH1 and TH17 responses and the severity of arthritis
    • (in press)
    • Lamacchia, C., Palmer, G., Seemayer, C. A., Talabot-Ayer, D. & Gabay, C. Myeloid-cell specific interleukin-1 receptor antagonist deficiency enhances TH1 and TH17 responses and the severity of arthritis. Arthritis Rheum. (in press).
    • Arthritis Rheum
    • Lamacchia, C.1    Palmer, G.2    Seemayer, C.A.3    Talabot-Ayer, D.4    Gabay, C.5
  • 8
    • 2542457495 scopus 로고    scopus 로고
    • Inflammatory caspases: Linking an intracellular innate immune system to autoinflammatory diseases
    • Martinon, F. & Tschopp, J. Inflammatory caspases: linking an intracellular innate immune system to autoinflammatory diseases. Cell 117, 561–574 (2004).
    • (2004) Cell , vol.117 , pp. 561-574
    • Martinon, F.1    Tschopp, J.2
  • 9
    • 0037792866 scopus 로고    scopus 로고
    • F. Interleukin-1-receptor antagonist in the Muckle–well syndrome
    • Hawkins P. N., Lachmann, H. J. & McDermott, M. F. interleukin-1-receptor antagonist in the Muckle–well syndrome. N. Engl. J. Med. 348, 2583–2584 (2003).
    • (2003) N. Engl. J. Med. , vol.348 , pp. 2583-2584
    • Hawkins, P.N.1    Lachmann, H.J.2    McDermott, M.3
  • 10
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    • Use of canakinumab in the cryopyrin-associated periodic syndrome
    • Lachmann, H. J. et al. Use of canakinumab in the cryopyrin-associated periodic syndrome. N. Engl. J. Med. 360, 2416–2425 (2009).
    • (2009) N. Engl. J. Med. , vol.360 , pp. 2416-2425
    • Lachmann, H.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.