-
1
-
-
34548310428
-
Sunitinib Malate for the Treatment of Metastatic Renal Cell Carcinoma and Gastrointestinal Stromal Tumors
-
DOI 10.1016/j.clinthera.2007.07.022, PII S0149291807002147
-
Adams VR, Leggas M: Sunitinib malate for the treatment of metastatic carcinoma and gastrointestinal stromal tumors. Clin Ther 29:1338-1353, 2007 (Pubitemid 47348120)
-
(2007)
Clinical Therapeutics
, vol.29
, Issue.7
, pp. 1338-1353
-
-
Adams, V.R.1
Leggas, M.2
-
2
-
-
34548278289
-
Influence of breast cancer resistance protein (Abcg2) and p-glycoprotein (Abcb1a) on the transport of imatinib mesylate (Gleevec) across the mouse blood-brain barrier
-
DOI 10.1111/j.1471-4159.2007.04808.x
-
Bihorel S, Camenisch G, Lemaire M, Scherrmann JM: Influence of breast cancer resistance protein (Abcg2) and pglycoprotein (Abcb1a) on the transport of imatinib mesylate (Gleevec) across the mouse blood-brain barrier. J Neurochem 102:1749-1757, 2007 (Pubitemid 47329285)
-
(2007)
Journal of Neurochemistry
, vol.102
, Issue.6
, pp. 1749-1757
-
-
Bihorel, S.1
Camenisch, G.2
Lemaire, M.3
Scherrmann, J.-M.4
-
3
-
-
38549160823
-
Cellular and in vivo activity of JNJ-28871063, a nonquinazoline pan-ErbB kinase inhibitor that crosses the blood-brain barrier and displays efficacy against intracranial tumors
-
DOI 10.1124/mol.107.041236
-
Emanuel SL, Hughes TV, Adams M, Rugg CA, Fuentes-Pesquera A, Connolly PJ, et al: Cellular and in vivo activity of JNJ-28871063, a nonquinazoline pan-ErbB kinase inhibitor that crosses the blood-brain barrier and displays efficacy against intracranial tumors. Mol Pharmacol 73:338-348, 2008 (Pubitemid 351159204)
-
(2008)
Molecular Pharmacology
, vol.73
, Issue.2
, pp. 338-348
-
-
Emanuel, S.L.1
Hughes, T.V.2
Adams, M.3
Rugg, C.A.4
Fuentes-Pesquera, A.5
Connolly, P.J.6
Pandey, N.7
Moreno-Mazza, S.8
Butler, J.9
Borowski, V.10
Middleton, S.A.11
Gruninger, R.H.12
Story, J.R.13
Napier, C.14
Hollister, B.15
Greenberger, L.M.16
-
4
-
-
33846148701
-
Sorafenib in advanced clear-cell renal-cell carcinoma
-
DOI 10.1056/NEJMoa060655
-
Escudier B, Eisen T, Stadler WM, Szczylik C, Oudard S, Siebels M, et al: Sorafenib in advanced clear-cell renal-cell carcinoma. N Engl J Med 356:125-134, 2007 (Pubitemid 46089673)
-
(2007)
New England Journal of Medicine
, vol.356
, Issue.2
, pp. 125-134
-
-
Escudier, B.1
Eisen, T.2
Stadler, W.M.3
Szczylik, C.4
Oudard, S.5
Siebels, M.6
Negrier, S.7
Chevreau, C.8
Solska, E.9
Desai, A.A.10
Rolland, F.11
Demkow, T.12
Hutson, T.E.13
Gore, M.14
Freeman, S.15
Schwartz, B.16
Shan, M.17
Simantov, R.18
Bukowski, R.M.19
-
5
-
-
33947423448
-
Approval summary: Sunitinib for the treatment of imatinib refractory or intolerant gastrointestinal stromal tumors and advanced renal cell carcinoma
-
DOI 10.1158/1078-0432.CCR-06-2328
-
Goodman VL, Rock EP, Dgher R, Ramchandani RP, Abraham S, Gobburur JV, et al: Approval summary: sunitinib for the treatment of imatinib refractory or intolerant gastrointestinal stromal tumors and advanced renal cell carcinoma. Clin Cancer Res 13:1367-1373, 2007 (Pubitemid 46450424)
-
(2007)
Clinical Cancer Research
, vol.13
, Issue.5
, pp. 1367-1373
-
-
Goodman, V.L.1
Rock, E.P.2
Dagher, R.3
Ramchandani, R.P.4
Abraham, S.5
Gobburu, J.V.S.6
Booth, B.P.7
Verbois, S.L.8
Morse, D.E.9
Liang, C.Y.10
Chidambaram, N.11
Jiang, J.X.12
Tang, S.13
Mahjoob, K.14
Justice, R.15
Pazdur, R.16
-
6
-
-
33750589845
-
Reversible posterior leukoencephalopathy syndrome induced by RAF kinase inhibitor BAY 43-9006
-
Govindarajan R, Adusumilli J, Baxter DL, El-Khoueiry A, Harik SI: Reversible posterior leukoencephalopathy syndrome induced by RAF kinase inhibitor BAY 43-9006. J Clin Oncol 24:e48, 2006
-
(2006)
J Clin Oncol
, vol.24
-
-
Govindarajan, R.1
Adusumilli, J.2
Baxter, D.L.3
El-Khoueiry, A.4
Harik, S.I.5
-
7
-
-
34547459725
-
Sorafenib and sunitinib: Novel targeted therapies for renal cell cancer
-
DOI 10.1592/phco.27.8.1125
-
Grandinetti CA, Goldspiel BR: Sorafenib and sunitinib: novel targeted therapies for renal cell cancer. Pharmacotherapy 27:1125-1144, 2007 (Pubitemid 47173659)
-
(2007)
Pharmacotherapy
, vol.27
, Issue.8
, pp. 1125-1144
-
-
Grandinetti, C.A.1
Goldspiel, B.R.2
-
8
-
-
0032780344
-
Clinical study of brain metastasis of renal cell carcinoma
-
DOI 10.1159/000068003
-
Harada Y, Nonomura N, Kondo M, Nishimura K, Takahara S, Miki T, et al: Clinical study of brain metastasis of renal cell carcinoma. Eur Urol 36:230-235, 1999 (Pubitemid 29381310)
-
(1999)
European Urology
, vol.36
, Issue.3
, pp. 230-235
-
-
Harada, Y.1
Nonomura, N.2
Kondo, M.3
Nishimura, K.4
Takahara, S.5
Miki, T.6
Okuyama, A.7
-
9
-
-
51649114000
-
Brain metastases in breast cancer: Prognostic factors and management
-
Lee SS, Ahn JH, Kim MK, Sym SJ, Gong G, Ahn SD, et al: Brain metastases in breast cancer: prognostic factors and management. Breast Cancer Res Treat 111:523-530, 2008
-
(2008)
Breast Cancer Res Treat
, vol.111
, pp. 523-530
-
-
Lee, S.S.1
Ahn, J.H.2
Kim, M.K.3
Sym, S.J.4
Gong, G.5
Ahn, S.D.6
-
10
-
-
34548169627
-
Reversible posterior leukoencephalopathy syndrome induced by sunitinib [10]
-
DOI 10.1200/JCO.2007.12.8710
-
Martín G, Bellido L, Cruz JJ: Reversible posterior leukoencephalopathy syndrome induced by sunitinib. J Clin Oncol 25:3559, 2007 (Letter) (Pubitemid 47310905)
-
(2007)
Journal of Clinical Oncology
, vol.25
, Issue.23
, pp. 3559
-
-
Martin, G.1
Bellido, L.2
Cruz, J.J.3
-
11
-
-
12244301581
-
In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: Determination of a pharmacokinetic/pharmacodynamic relationship
-
Mendel DB, Laird AD, Xin X, Louie SG, Christensen JG, Li G, et al: In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: determination of a pharmacokinetic/pharmacodynamic relationship. Clin Cancer Res 9:327-337, 2003 (Pubitemid 36109749)
-
(2003)
Clinical Cancer Research
, vol.9
, Issue.1 I
, pp. 327-337
-
-
Mendel, D.B.1
Douglas Laird, A.2
Xin, X.3
Louie, S.G.4
Christensen, J.G.5
Li, G.6
Schreck, R.E.7
Abrams, T.J.8
Ngai, T.J.9
Lee, L.B.10
Murray, L.J.11
Carver, J.12
Chan, E.13
Moss, K.G.14
Haznedar, J.O.15
Sukbuntherng, J.16
Blake, R.A.17
Sun, L.18
Tang, C.19
Miller, T.20
Shirazian, S.21
McMahon, G.22
Cherrington, J.M.23
more..
-
12
-
-
33846181370
-
Sunitinib versus interferon alfa in metastatic renal-cell carcinoma
-
DOI 10.1056/NEJMoa065044
-
Motzer RJ, Hutson TE, Tomczak P, Michaelson MD, Bukowski RM, Rixe O, et al: Sunitinib versus interferon alfa in metastatic renal-cell carcinoma. N Engl J Med 356:115-124, 2007 (Pubitemid 46089672)
-
(2007)
New England Journal of Medicine
, vol.356
, Issue.2
, pp. 115-124
-
-
Motzer, R.J.1
Hutson, T.E.2
Tomczak, P.3
Michaelson, D.4
Bukowski, R.M.5
Rixe, O.6
Oudard, S.7
Negrier, S.8
Szczylik, C.9
Kim, S.T.10
Chen, I.11
Bycott, P.W.12
Baum, C.M.13
Figlin, R.A.14
-
13
-
-
33744954585
-
Sunitinib in patients with metastatic renal cell carcinoma
-
DOI 10.1001/jama.295.21.2516
-
Motzer RJ, Rini BI, Bukowski RM, Curti BD, George DJ, Hudes GR, et al: Sunitinib in patients with metastatic renal cell carcinoma. JAMA 295:2516-2524, 2006 (Pubitemid 43854967)
-
(2006)
Journal of the American Medical Association
, vol.295
, Issue.21
, pp. 2516-2524
-
-
Motzer, R.J.1
Rini, B.I.2
Bukowski, R.M.3
Curti, B.D.4
George, D.J.5
Hudes, G.R.6
Redman, B.G.7
Margolin, K.A.8
Merchan, J.R.9
Wilding, G.10
Ginsberg, M.S.11
Bacik, J.12
Kim, S.T.13
Baum, C.M.14
Michaelson, M.D.15
-
14
-
-
33744984843
-
Phase II placebo-controlled randomized discontinuation trial of sorafenib in patients with metastatic renal cell carcinoma
-
DOI 10.1200/JCO.2005.03.6723
-
Ratain MJ, Eisen T, Stadler WM, Flaherty KT, Kaye SB, Rosner GL, et al: Phase II placebo-controlled randomized discontinuation trial of sorafenib in patients with metastatic renal cell carcinoma. J Clin Oncol 24:2505-2512, 2006 (Pubitemid 46630627)
-
(2006)
Journal of Clinical Oncology
, vol.24
, Issue.16
, pp. 2505-2512
-
-
Ratain, M.J.1
Eisen, T.2
Stadler, W.M.3
Flaherty, K.T.4
Kaye, S.B.5
Rosner, G.L.6
Gore, M.7
Desai, A.A.8
Patnaik, A.9
Xiong, H.Q.10
Rowinsky, E.11
Abbruzzese, J.L.12
Xia, C.13
Simantov, R.14
Schwartz, B.15
O'Dwyer, P.J.16
-
15
-
-
4944249117
-
BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis
-
DOI 10.1158/0008-5472.CAN-04-1443
-
Wilhelm SM, Carter C, Tang L, Wilkie D, McNabola A, Rong H, et al: BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis. Cancer Res 64:7099-7109, 2004 (Pubitemid 39331023)
-
(2004)
Cancer Research
, vol.64
, Issue.19
, pp. 7099-7109
-
-
Wilhelm, S.M.1
Carter, C.2
Tang, L.3
Wilkie, D.4
McNabola, A.5
Rong, H.6
Chen, C.7
Zhang, X.8
Vincent, P.9
McHugh, M.10
Cao, Y.11
Shujath, J.12
Gawlak, S.13
Eveleigh, D.14
Rowley, B.15
Liu, L.16
Adnane, L.17
Lynch, M.18
Auclair, D.19
Taylor, I.20
Gedrich, R.21
Voznesensky, A.22
Riedl, B.23
Post, L.E.24
Bollag, G.25
Trail, P.A.26
more..
|