Use of C-reactive protein to predict outcome in dogs with systemic inflammatory response syndrome or sepsis: Original Study

Journal of Veterinary Emergency and Critical Care

Volumn 19, Issue 5, 2009, Pages 450-458

  Gebhardt, Constance ^a,b,c   Hirschberger, Johannes ^a,b,c   Rau, Stefanie ^a,b,c   Arndt, Gisela ^a,b,c   Krainer, Karen ^a,b,c   Schweigert, Florian J ^a,b,c   Brunnberg, Leo ^a,b,c   Kaspers, Bernd ^a,b,c   Kohn, Barbara ^a,b,c  

^a FREIE UNIVERSITÄT BERLIN   (Germany)

^b UNIVERSITY OF MUNICH   (Germany)

^c UNIVERSITY OF POTSDAM   (Germany)

Author keywords

Acute phase proteins; CRP; Prognosis; Survival prediction; Systemic inflammation

Indexed keywords

C REACTIVE PROTEIN;

ANIMAL; ANIMAL DISEASE; ARTICLE; BLOOD; CRITICAL ILLNESS; DOG; DOG DISEASE; FEMALE; MALE; METABOLISM; MORTALITY; PROSPECTIVE STUDY; SEPSIS; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME;

ANIMALS; C-REACTIVE PROTEIN; CRITICAL ILLNESS; DOG DISEASES; DOGS; FEMALE; MALE; PROSPECTIVE STUDIES; SEPSIS; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME;

ANIMALIA; CANIS FAMILIARIS;

EID: 70350500447     PISSN: 14793261     EISSN: 14764431     Source Type: Journal    
DOI: 10.1111/j.1476-4431.2009.00462.x     Document Type: Article

References (37)

1. Angus DC, Linde-Zwirble WT, Lidicker J, et al. Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care. Crit Care Med 2001 29 (7) : 1303 1310.
2. Danai P, Martin GS. Epidemiology of sepsis: recent advances. Curr Infect Dis Rep 2005 7 (5) : 329 334.
3. Martin GS, Mannino DM, Eaton S, et al. The epidemiology of sepsis in the United States from 1979 through 2000. N Engl J Med 2003 348 (16) : 1546 1554.
4. Marx G, Schuerholz T, Reinhart K. New approaches to intensive care for sepsis. Der Chirurg 2005 76 (9) : 845 855.
5. de Laforcade AM, Freeman LM, Shaw SP, et al. Hemostatic changes in dogs with naturally occurring sepsis. J Vet Intern Med 2003 17 (5) : 674 679.
6. Greenfield CL, Walshaw R. Open peritoneal drainage in the treatment of contaminated peritoneal cavity and septic peritonitis in dogs and cats: 24 cases (1980-1986). J Am Vet Med Assoc 1987 191 (1) : 100 105.
7. King LG. Postoperative complications and prognostic indicators in dogs and cats with septic peritonitis: 23 cases (1989-1992). J Am Vet Med Assoc 1994 204 (3) : 407 414.
8. Otto CM. Sepsis, In : Wingfield WE. ed. The Veterinary ICU Book. Jackson Hole, WY : Teton NewMedia 2002, pp. 695 709.
9. American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference: definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Crit Care Med 1992 20 (6) : 864 874.
10. Hauptman JG, Walshaw R, Olivier NB. Evaluation of the sensitivity and specificity of diagnostic criteria for sepsis in dogs. Vet Surg 1997 26 (5) : 393 397.
11. Holm JL, Rozanski EA, Freeman LM, et al. C-reactive protein concentrations in canine acute pancreatitis. J Vet Emerg Crit Care 2004 14 (3) : 183 186.
12. Kent J. Acute phase proteins: their use in veterinary diagnosis. Br Vet J 1992 148 (4) : 279 281.
13. Ceron JJ, Eckersall PD, Martynez-Subiela S. Acute phase proteins in dogs and cats: current knowledge and future perspectives. Vet Clin Pathol 2005 34 (2) : 85 99.
14. Annane D, Bellissant E, Cavaillon JM. Septic shock. Lancet 2005 365 (9453) : 63 78.
15. Castelli GP, Pognani C, Meisner M, et al. Procalcitonin and C-reactive protein during systemic inflammatory response syndrome, sepsis and organ dysfunction. Crit Care 2004 8 (4) : R234 R242.
16. Jaswal RS, Kaushal RK, Goel A, et al. Role of C-reactive protein in deciding duration of antibiotic therapy in neonatal septicemia. Indian Pediatr 2003 40 (9) : 880 883.
17. Kolb-Bachofen V. A review on the biological properties of C-reactive protein. Immunobiology 1991 183 (1-2) : 133 145.
18. Póvoa P, Coelho L, Almeida E, et al. C-reactive protein as a marker of infection in critically ill patients. Clin Microbiol Infect 2005 11 (2) : 101 108.
19. Yamamoto S, Shida T, Miyaji S, et al. Changes in serum C-reactive protein levels in dogs with various disorders and surgical traumas. Vet Res Commun 1993 17 (2) : 85 93.
20. Yamamoto S, Shida T, Okimura T, et al. Determination of C-reactive protein in serum and plasma from healthy dogs and dogs with pneumonia by ELISA and slide reversed passive latex agglutination test. Vet Q 1994 16 (2) : 74 77.
21. Otabe K, Ito T, Sugimoto T, et al. C-reactive protein (CRP) measurement in canine serum following experimentally-induced acute gastric mucosal injury. Lab Anim 2000 34 (4) : 434 438.
22. Fransson BA, Karlstam E, Bergstrom A, et al. C-reactive protein in the differentiation of pyometra from cystic endometrial hyperplasia/ucometra in dogs. J Am Anim Hosp Assoc 2004 40 (5) : 391 399.
23. Martinez-Subiela S, Tecles F, Eckersall PD, et al. Serum concentrations of acute phase proteins in dogs with leishmaniasis. Vet Rec 2002 15 (8) : 241 244.
24. Rikihisa Y, Yamamoto S, Kwak I, et al. C-reactive protein and alpha 1-acid glycoprotein levels in dogs infected with ehrlichia canis. J Clin Microbiol 1994 3 (4) : 912 917.
25. Kjelgaard-Hansen M, Kristensen AT, Jensen AL. Evaluation of a commercially available enzyme-linked immunosorbent assay (ELISA) for the determination of C-reactive protein in canine serum. J Vet Med A Physiol Pathol Clin Med 2003 50 (3) : 164 168. (Pubitemid 41726282)
26. Aalto H, Takala A, Kautiainen H, et al. Laboratory markers of systemic inflammation as predictors of bloodstream infection in acutely ill patients admitted to hospital in medical emergency. Eur J Clin Microbiol Infect Dis 2004 23 (9) : 699 704.
27. Brady CA, Otto CM, Van Winkle TJ, et al. Severe sepsis in cats: 29 cases (1986-1998). J Am Vet Med Assoc 2000 217 (4) : 531 535.
28. Richards MJ, Edwards JR, Culver DH, et al. Nosocomial infections in medical intensive care units in the United States. National nosocomial infections surveillance system. Crit Care Med 1999 27 (5) : 887 892.
29. Aronson MD, Bor DH. Blood cultures. Ann Intern Med 1987 106 (2) : 246 253.
30. Caspi D, Snel FW, Batt RM, et al. C-reactive protein in dogs. Am J Vet Res 1987 48 (6) : 919 921.
31. Burton SA, Honor DJ, Mackenzie AL, et al. C-reactive protein concentration in dogs with inflammatory leukograms. Am J Vet Res 1994 55 (5) : 613 618.
32. Fransson BA, Lagerstedt AS, Bergstrom A, et al. C-reactive protein, tumor necrosis factor α, and interleukin-6 in dogs with pyometra and SIRS. J Vet Emerg Crit Care 2007 17 (4) : 373 381.
33. Yentis SM, Soni N, Sheldon J. C-reactive protein as an indicator of resolution of sepsis in the intensive care unit. Intensive Care Med 1995 21 (7) : 602 605.
34. Bomela HN, Ballot DE, Cory BJ, et al. Use of C-reactive protein to guide duration of empiric antibiotic therapy in suspected early neonatal sepsis. Pediatr Infect Dis J 2000 19 (6) : 531 535.
35. Vincent JL, de Mendonca A, Cantraine F, et al. Use of the SOFA score to assess the incidence of organ dysfunction/failure in intensive care units: results of a multicenter, prospective study. Working group on "sepsis-related problems" of the European Society of Intensive Care Medicine. Crit Care Med 1998 26 (11) : 1793 1800.
36. King LG, Stevens MT, Ostro ENS, et al. A model for prediction of survival in critically ill dogs. J Vet Emerg Crit Care 1994 4 (2) : 85 99.
37. King LG, Fordyce H, Campellone M, et al. Serial estimation of survival prediction indices does not improve outcome prediction in critically ill dogs with naturally occurring disease. J Vet Emerg Crit Care 2001 11 (3) : 183 189.