Association of programmed cell death factor 4 (PDCD4) with hepatocellular carcinoma and smoking in a Chinese male population

Journal of International Medical Research

Volumn 37, Issue 4, 2009, Pages 1179-1183

  Jiang, Y ^a   Zhang, S H H ^a   Han, G Q ^a   Qin, Cheng Yong ^a  

^a SHANDONG UNIVERSITY   (China)

Author keywords

Hepatocellular carcinoma; Programmed cell death factor 4 (PDCD4); Tobacco smoking

Indexed keywords

PROGRAMMED CELL DEATH FACTOR 4; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG; APOPTOSIS REGULATORY PROTEIN; PDCD4 PROTEIN, HUMAN; RNA BINDING PROTEIN;

ADULT; AGED; ARTICLE; CHINESE; CONTROLLED STUDY; GENE EXPRESSION; GENE IDENTIFICATION; GENETIC ASSOCIATION; HOSPITAL BASED CASE CONTROL STUDY; HUMAN; HUMAN TISSUE; LIVER CELL CARCINOMA; MAJOR CLINICAL STUDY; MALE; SMOKING; TUMOR SUPPRESSOR GENE; WESTERN BLOTTING; CASE CONTROL STUDY; CHINA; LIVER TUMOR; METABOLISM; MIDDLE AGED; PATHOLOGY;

ADULT; AGED; APOPTOSIS REGULATORY PROTEINS; BLOTTING, WESTERN; CARCINOMA, HEPATOCELLULAR; CASE-CONTROL STUDIES; CHINA; HUMANS; LIVER NEOPLASMS; MALE; MIDDLE AGED; RNA-BINDING PROTEINS; SMOKING;

EID: 70350474965     PISSN: 03000605     EISSN: None     Source Type: Journal    
DOI: 10.1177/147323000903700424     Document Type: Article

References (15)

1. Mizoue T, Tokui N, Nishisaka K, et al: Prospective study on the relation of cigarette smoking with cancer of the liver and stomach in an endemic region. Int J Epidemiol 2000; 29: 232-237. (Pubitemid 30209812)
2. Mori Y, Koide A, Kobayashi Y, et al: Effects of cigarette smoke and a heterocyclic amine, MeIQx on cytochrome P-450, mutagenic activation of various carcinogens and glucuronidation in rat liver. Mutagenesis 2003; 18: 87-93. (Pubitemid 36113611)
3. Mitacek EJ, Brunnemann KD, Hoffmann D, et al: Volatile nitrosamines and tobacco-specific nitrosamines in the smoke of Thai cigarettes: a risk factor for lung cancer and a suspected risk factor for liver cancer in Thailand. Carcinogenesis 1999; 20: 133-137. (Pubitemid 29033855)
4. Karube T, Odagiri Y, Takemoto K, et al: Analyses of transplacentally induced sister chromatid exchanges and micronuclei in mouse fetal liver cells following maternal exposure to cigarette smoke. Cancer Res 1989; 49: 3550-3552. (Pubitemid 19178173)
5. Shibahara K, Asano M, Ishida Y, et al: Isolation of a novel mouse gene MA-3 that is induced upon programmed cell death. Gene 1995; 166: 297-301.
6. Cmarik JL, Min H, Hegamyer G, et al: Differentially expressed protein Pdcd4 inhibits tumor promoter-induced neoplastic transformation. Proc Natl Acad Sci USA 1999; 96: 14037-14042.
7. Jansen AP, Camalier CE, Colburn NH: Epidermal expression of the translation inhibitor programmed cell death 4 suppresses tumorigenesis. Cancer Res 2005; 65: 6034-6041.
8. Lin Y, Liu X, Cheng Y: Involvement of microRNAs in hydrogen peroxide-mediated gene regulation and cellular injury response in vascular smooth muscle cells. J Biol Chem 2009; 284: 7903-7913.
9. Frankel LB, Christoffersen NR, Jacobsen A, et al: Programmed cell death 4 (PDCD4) is an important functional target of the microRNA miR-21 in breast cancer cells. J Biol Chem 2008; 283: 1026-1033.
10. Schmid T, Jansen AP, Baker AR, et al: Translation inhibitor Pdcd4 is targeted for degradation during tumor promotion. Cancer Res 2008; 68: 1254-1260. (Pubitemid 351346830)
11. Yang HS, Jansen AP, Komar AA, et al: The transformation suppressor Pdcd4 is a novel eukaryotic translation initiation factor 4A binding protein that inhibits translation. Mol Cell Biol 2003; 23: 26-37.
12. Bitomsky N, Böhm M, Klempnauer KH: Transformation suppressor protein Pdcd4 interferes with JNK-mediated phosphorylation of c-Jun and recruitment of the coactivator p300 by c-Jun. Oncogene 2004; 23: 7484-7493. (Pubitemid 39389690)
13. Jansen AP, Camalier CE, Stark C, et al: Characterization of programmed cell death 4 in multiple human cancers reveals a novel enhancer of drug sensitivity. Mol Cancer Ther 2004; 3: 103-110. (Pubitemid 39193684)
14. Palamarchuk A, Efanov A, Maximov V, et al: Akt phosphorylates and regulates Pdcd4 tumor suppressor protein. Cancer Res 2005; 65: 11282-11286. (Pubitemid 41821683)
15. Dorrello NV, Peschiaroli A, Guardavaccaro D, et al: S6K1- and βTRCP-mediated degradation of PDCD4 promotes protein translation and cell growth. Science 2006; 314: 467-471. (Pubitemid 44628968)