Potential use of microarray technology at the U.S. environmental protection agency

Genomics: Fundamentals and Applications

Volumn , Issue , 2008, Pages 379-398

  Haymes, Kenneth M ^a   Hester, Susan D ^b   Benson, William H ^b   McClintock, J Thomas ^c  

^a U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^b U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^c and Toxic Substances   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 70350468112     PISSN: None     EISSN: None     Source Type: Book    
DOI: None     Document Type: Chapter

References (30)

1. US Environmental Protection Agency, Science Policy Council. Interim Policy on Genomics. 2002. http://www.epa.gov/osa/spc/genomics.htm.
2. US Environmental Protection Agency, Science Policy Council. Potential Implications of Genomics for Regulatory and Risk Assessment Applications at EPA. EPA 100/B-04/002, 2004. http://www.epa.gov/osa/genomics.htm.
3. US Environmental Protection Agency, Science Policy Council. External review draft of Interim Guidance for Microarray-Based Assays: Data Submission, Quality, Analysis, Management, and Training Considerations. EPA 100/B-06/003, 2006. htttp://www/epa.gov/OSA/spc/pdfs/epa_ interim_guidance:for_microarray-based_assays-external-review_draft.pdf.
4. Benson WH, Gallagher K, McClintock JT. US Environmental Protection Agency’s Activities to Prepare for Regulatory and Risk Assessment Applications of Genomics Information. Environ Mol Mutagen 2007; 48: 359-362.
5. US Environmental Protection Agency, Guidelines for Carcinogen Risk Assessment. EPA/630/P-03/001F, 2005. http://cfpub.epa.gov/ncea/cfm/recordisplay.cfm?deid-116283.
6. de Longueville F, Surry D, Meneses-Lorente G, et al. Gene expression profiling of drug metabolism and toxicology markers using a low-density DNA microarray. Biochem Pharmacol 2002; 64: 137-149.
7. Huang Q, Jin X, Gaillard ET, et al. Gene expression profiling reveals multiple toxicity endpoints induced by hepatotoxicants. Mutat Res 2004; 549: 147-167.
8. Kier LD, Neft R, Tang L, et al. Applications of microarrays with toxicologically relevant genes (tox genes) for the evaluation of chemical toxicants in Sprague Dawley rats in vivo and human hepatocytes in vitro. Mutat Res 2004; 549: 101-113.
9. McMillian M, Nie AY, Parker JB, et al. A gene expression signature for oxidant stress/reactive metabolites in rat liver. Biochem Pharmacol 2004; 68: 2249-2261.
10. Meneses-Lorente G, de Longueville F, Dos Santos-Mendes S, et al. An evaluation of a low-density DNA microarray using cytochrome P450 inducers. Chem Res Toxicol 2003; 16: 1070-1077.
11. Waring JF, Jolly RA, Ciurlionis R, et al. Clustering of hepatotoxins based on mechanism of toxicity using gene expression profiles. Toxicol Appl Pharmacol 2001; 175: 28-42.
12. Glatt CM, Ouyang M, Welsh W, et al. Molecular characterization of thyroid toxicity: anchoring gene expression profiles to biochemical and pathologic end points. Environ Health Perspect 2005; 113: 1354-1361.
13. Shih CH, Chen SL, Yen CC, et al. Thyroid hormone receptor-dependent transcriptional regulation of fibrinogen and coagulation proteins. Endocrinology 2004; 145: 2804-2814.
14. Hill RN, Crisp TM, Hurley PM, et al. Risk assessment of thyroid follicular cell tumors. Environ Health Perspect 1998; 106: 447-457.
15. Hurley PM. Mode of carcinogenic action of pesticides inducing thyroid follicular cell tumors in rodents. Environ Health Perspect 1998; 106: 437-445.
16. Hester SD, Nesnow S. Transcriptional responses in thyroid tissues from rats treated with a tumorigenic and a non-tumorigenic triazole conazole fungicide. Toxicol Appl Pharmacol 2008; 227: 357-369.
17. Cohen SM, Arnold LL, Uzvolgyi E, et al. Possible role of dimethylarsinous acid in dimethylarsinic acid-induced urothelial toxicity and regeneration in the rat. Chem Res Toxicol 2002; 15: 1150-1157.
18. Cohen SM, Yamamoto S, Cano M, et al. Urothelial cytotoxicity and regeneration induced by dimethylarsinic acid in rats. Toxicol Sci 2001; 59: 68-74.
19. Cohen SM, Ohnishi T, Arnold LL, et al. Arsenic-induced bladder cancer in an animal model. Toxicol Appl Pharmacol 2007; 222: 258-263.
20. Brauer M, Hoek G, van Vliet P, et al. Estimating long-term average particulate air pollution concentrations: application of traffic indicators and geographic information systems. Epidemiology 2003; 14: 228-239.
21. Hwang BF, Lee YL, Lin YC, et al. Traffic related air pollution as a determinant of asthma among Taiwanese school children. Thorax 2005; 60: 467-473.
22. Matsumoto A, Hiramatsu K, Li Y, et al. Repeated exposure to low-dose diesel exhaust after allergen challenge exaggerates asthmatic responses in mice. Clin Immunol 2006; 121: 227-235.
23. Steerenberg PA, Withagen CE, Dormans JA, et al. Adjuvant activity of various diesel exhaust and ambient particles in two allergic models. J Toxicol Environ Health A 2003; 66: 1421-1439.
24. Hiura TS, Kaszubowski MP, Li N, et al. Chemicals in diesel exhaust particles generate reactive oxygen radicals and induce apoptosis in macrophages. J Immunol 1999; 163: 5582-5591.
25. Li N, Venkatesan MI, Miguel A, et al. Induction of heme oxygenase-1 expression in macrophages by diesel exhaust particle chemicals and quinones via the antioxidant-responsive element. J Immunol 2000; 165: 3393-3401.
26. Li N, Wang M, Oberley TD, et al. Comparison of the pro-oxidative and proinflammatory effects of organic diesel exhaust particle chemicals in bronchial epithelial cells and macrophages. J Immunol 2002; 169: 4531-4541.
27. Fujimaki H, Kurokawa Y. Diesel exhaust-associated gas components enhance chemokine production by cervical lymph-node cells from mice immunized with sugi basic proteins. Inhal Toxicol 2004; 16: 61-65.
28. Gilmour MI, Selgrade MJ. A model of immune-mediated lung disease in rats sensitized to house dust mite and upregulation of immunity following exposure to nitrogen dioxide. Chest 1996; 109: 69S.
29. Stevens T, Krantz QT, Linak WP, et al. Increased transcription of immune and metabolic pathways in naïve and allergic mice exposed to diesel exhaust. Toxicol Sci 2008; 102: 359-370.
30. Li N, Hao M, Phalen RF, et al. Particulate air pollutants and asthma: a paradigm for the role of oxidative stress in PM-induced adverse health effects. Clin Immunol 2003; 109: 250-265.