Mechanism of cyclizing NAD to cyclic ADP-ribose by ADP-ribosyl cyclase and CD38

Journal of Biological Chemistry

Volumn 284, Issue 40, 2009, Pages 27629-27636

  Graeff, Richard ^a   Liu, Qun ^b   Kriksunov, Irina A ^b   Kotaka, Masayo ^c   Oppenheimer, Norman ^d   Hao, Quan ^b,c   Lee, Hon Cheung ^a,c  

^a UNIVERSITY OF MINNESOTA   (United States)

^b Cornell University ^*  (United States)

^c UNIVERSITY OF HONG KONG   (Hong Kong)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENINE RING; ADP-RIBOSE; APLYSIA; CATALYTIC RESIDUE; CELLULAR FUNCTION; CYCLASES; CYCLIC ADP-RIBOSE (CADPR); DINUCLEOTIDES; DOUBLE MUTATION; IN-VIVO; LINEAR SUBSTRATES; STABLE COMPLEXES;

AMIDES; BIOCHEMICAL ENGINEERING; BIOLOGICAL RADIATION EFFECTS; CALCIUM; CATALYSTS; CRYSTAL STRUCTURE; ENZYMES; MAMMALS;

SUBSTRATES;

ADENOSINE DIPHOSPHATE RIBOSYL CYCLASE; CD38 ANTIGEN; CYCLIC ADENOSINE DIPHOSPHATE RIBOSE; NICOTINAMIDE ADENINE DINUCLEOTIDE; CALCIUM;

AMINO ACID SUBSTITUTION; ARTICLE; CATALYSIS; COMPLEX FORMATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; CYCLIZATION; ENZYME SUBSTRATE; MUTATIONAL ANALYSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FOLDING; ANIMAL; BIOCATALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; ENZYME SPECIFICITY; GENETICS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METABOLISM; MUTATION; PROTEIN CONFORMATION; PROTEIN ENGINEERING; SITE DIRECTED MUTAGENESIS; X RAY CRYSTALLOGRAPHY;

APLYSIA; MAMMALIA;

ANIMALS; ANTIGENS, CD38; BIOCATALYSIS; CALCIUM; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CRYSTALLOGRAPHY, X-RAY; CYCLIC ADP-RIBOSE; CYCLIZATION; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; MUTATION; NAD; PROTEIN CONFORMATION; PROTEIN ENGINEERING; SUBSTRATE SPECIFICITY;

EID: 70350453607     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.030965     Document Type: Article

References (39)

1. Clapper, D. L., Walseth, T. F., Dargie, P. J., and Lee, H. C. (1987) J. Biol. Chem. 262, 9561-9568
2. Lee, H. C., Walseth, T. F., Bratt, G. T., Hayes, R. N., and Clapper, D. L. (1989) J. Biol. Chem. 264, 1608-1615
3. Lam, C. M., Yeung, P. K., Lee, H. C., and Wong, J. T. (2009) Cell Calcium 45, 346-357
4. Jin, D., Liu, H. X., Hirai, H., Torashima, T., Nagai, T., Lopatina, O., Shnayder, N. A., Yamada, K., Noda, M., Seike, T., Fujita, K., Takasawa, S., Yokoyama, S., Koizumi, K., Shiraishi, Y., Tanaka, S., Hashii, M., Yoshihara, T., Higashida, K., Islam, M. S., Yamada, N., Hayashi, K., Noguchi, N., Kato, I., Okamoto, H., Matsushima, A., Salmina, A., Munesue, T., Shimizu, N., Mochida, S., Asano, M., and Higashida, H. (2007) Nature 446, 41-45
5. Lee, H. C. (2002) Cyclic ADP-ribose and NAADP: Structures, Metabolism and Functions, Kluwer Academic Publishers, Dordrecht, The Netherlands
6. Lee, H. C. (2004) Curr. Mol. Med. 4, 227-237
7. Lee, H. C., and Aarhus, R. (1991) Cell Regul. 2, 203-209
8. Mothet, J. P., Fossier, P., Meunier, F. M., Stinnakre, J., Tauc, L., and Baux, G. (1998) J. Physiol. 507.2, 405-414
9. Bezin, S., Charpentier, G., Lee, H. C., Baux, G., Fossier, P., and Cancela, J. M. (2008) J. Biol. Chem. 283, 27859-27870
10. Kato, I., Yamamoto, Y., Fujimura, M., Noguchi, N., Takasawa, S., and Okamoto, H. (1999) J. Biol. Chem. 274, 1869-1872
11. Partida-Sánchez, S., Cockayne, D. A., Monard, S., Jacobson, E. L., Oppenheimer, N., Garvy, B., Kusser, K., Goodrich, S., Howard, M., Harmsen, A., Randall, T. D., and Lund, F. E. (2001) Nat. Med. 7, 1209-1216
12. Howard, M., Grimaldi, J. C., Bazan, J. F., Lund, F. E., Santos-Argumedo, L., Parkhouse, R. M., Walseth, T. F., and Lee, H. C. (1993) Science 262, 1056-1059
13. Kim, H., Jacobson, E. L., and Jacobson, M. K. (1993) Science 261, 1330-1333
14. Lee, H. C., Zocchi, E., Guida, L., Franco, L., Benatti, U., and De Flora, A. (1993) Biochem. Biophys. Res. Commun. 191, 639-645
15. Takasawa, S., Tohgo, A., Noguchi, N., Koguma, T., Nata, K., Sugimoto, T., Yonekura, H., and Okamoto, H. (1993) J. Biol. Chem. 268, 26052-26054
16. Aarhus, R., Graeff, R. M., Dickey, D. M., Walseth, T. F., and Lee, H. C. (1995) J. Biol. Chem. 270, 30327-30333
17. Lee, H. C., and Aarhus, R. (1995) J. Biol. Chem. 270, 2152-2157
18. Churchill, G. C., Okada, Y., Thomas, J. M., Genazzani, A. A., Patel, S., and Galione, A. (2002) Cell 111, 703-708
19. Galione, A. (2006) Biochem. Soc. Trans. 34, 922-926
20. Guse, A. H., and Lee, H. C. (2008) Sci. Signal. 1, re10
21. Munshi, C., Aarhus, R., Graeff, R., Walseth, T. F., Levitt, D., and Lee, H. C. (2000) J. Biol. Chem. 275, 21566-21571
22. Munshi, C., Thiel, D. J., Mathews, I. I., Aarhus, R., Walseth, T. F., and Lee, H. C. (1999) J. Biol. Chem. 274, 30770-30777
23. Bradford, M. M. (1976) Anal. Biochem. 72, 248-254
24. Sleath, P. R., Handlon, A. L., and Oppenheimer, N. J. (1991) J. Org. Chem. 56, 3608-3613
25. Otwinowski, Z., and Minor, W. (1997) Macromol. Crystallog., Pt. A. 276, 307-326
26. Jones, T. A., Zou, J. Y., Cowan, S. W., and Kjeldgaard, M. (1991) Acta Crystallogr. A 47, 110-119
27. Schüttelkopf, A. W., and van Aalten, D. M. F. (2004) Acta Crystallogr. D Biol. Crystallogr. 60, 1355-1363
28. Morris, R. J., Perrakis, A., and Lamzin, V. S. (2003) Macromol. Crystallog., Pt. D. 374, 229-244
29. Graeff, R. M., and Lee, H. C. (2003) Comb. Chem. High Throughput Screen 6, 367-379
30. Graeff, R., and Lee, H. C. (2002) Biochem. J. 361, 379-384
31. Love, M. L., Szebenyi, D. M., Kriksunov, I. A., Thiel, D. J., Munshi, C., Graeff, R., Lee, H. C., and Hao, Q. (2004) Structure 12, 477-486
32. Prasad, G. S., McRee, D. E., Stura, E. A., Levitt, D. G., Lee, H. C., and Stout, C. D. (1996) Nat. Struct. Biol. 3, 957-964
33. Sauve, A. A., Deng, H. T., Angeletti, R. H., and Schramm, V. L. (2000) J.Am Chem. Soc. 122, 7855-7859
34. Liu, Q., Kriksunov, I. A., Jiang, H., Graeff, R., Lin, H., Lee, H. C., and Hao, Q. (2008) Chem Biol 15, 1068-1078
35. Liu, Q., Graeff, R., Kriksunov, I. A., Jiang, H., Zhang, B., Potter, B. V. L., Oppenheimer, N., Lin, H., Lee, H. C., and Hao, Q. (2009) J. Biol. Chem. 284, 27637-27645
36. Liu, Q., Kriksunov, I. A., Graeff, R., Munshi, C., Lee, H. C., and Hao, Q. (2006) J. Biol. Chem. 281, 32861-32869
37. Graeff, R. M., Walseth, T. F., Fryxell, K., Branton, W. D., and Lee, H. C. (1994) J. Biol. Chem. 269, 30260-30267
38. Graeff, R. M., Walseth, T. F., Hill, H. K., and Lee, H. C. (1996) Biochemistry 35, 379-386
39. Graeff, R., Munshi, C., Aarhus, R., Johns, M., and Lee, H. C. (2001) J. Biol. Chem. 276, 12169-12173