-
2
-
-
0029854741
-
The combinatorial chemistry of nature
-
Verdine GL. The combinatorial chemistry of nature. Nature 1996;384:11-13.
-
(1996)
Nature
, vol.384
, pp. 11-13
-
-
Verdine, G.L.1
-
3
-
-
0028896147
-
The value of undiscovered pharmaceuticals in tropical forests
-
Mendelson R, Balick MJ. The value of undiscovered pharmaceuticals in tropical forests. Econ Bot 1995;49:223-228.
-
(1995)
Econ Bot
, vol.49
, pp. 223-228
-
-
Mendelson, R.1
Balick, M.J.2
-
4
-
-
19644393308
-
Bioactive microbial metabolites: A personal view
-
Berdy J. Bioactive microbial metabolites. A personal view. J Antibiot 2005;58:1-26. (Pubitemid 40299637)
-
(2005)
Journal of Antibiotics
, vol.58
, Issue.1
, pp. 1-26
-
-
Berdy, J.1
-
6
-
-
0033104653
-
Statistical investigation into the structural complementarity of natural products and synthetic compounds
-
DOI 10.1002/(SICI)1521-3773(19990301)38:5<643::AID-ANIE643>3.0. CO;2-G
-
Henkel T, Brunne RM, Müller H, Reichel F. Statistical investigation into the structural complementarity of natural products and synthetic compounds. Angew Chem Int Ed Engl 1999;38:643-647. (Pubitemid 29129819)
-
(1999)
Angewandte Chemie - International Edition
, vol.38
, Issue.5
, pp. 643-647
-
-
Henkel, T.1
Brunne, R.M.2
Muller, H.3
Reichel, F.4
-
7
-
-
0242575114
-
Diversifying microbial natural products for drug discovery
-
DOI 10.1007/s00253-003-1381-9
-
Knight V, Sanglier JJ, DiTullio D, et al. Diversifying microbial natural products for drug discovery. Appl Microbiol Biotechnol 2003;62:446-458. (Pubitemid 37372436)
-
(2003)
Applied Microbiology and Biotechnology
, vol.62
, Issue.5-6
, pp. 446-458
-
-
Knight, V.1
Sanglier, J.-J.2
Ditullio, D.3
Braccili, S.4
Bonner, P.5
Waters, J.6
Hughes, D.7
Zhang, L.8
-
10
-
-
0029840799
-
Genetically engineered synthesis of natural products: From alkaloids to corrins
-
Roessner CA, Scott AI. Genetically engineered synthesis of natural products: From alkaloids to corrins. Ann Rev Microbiol 1996;50:467-490.
-
(1996)
Ann Rev Microbiol
, vol.50
, pp. 467-490
-
-
Roessner, C.A.1
Scott, A.I.2
-
11
-
-
0042844744
-
Natural products as sources of new drugs over the period 1981-2002
-
Newman DJ, Cragg GM, Snader KM. Natural products as sources of new drugs over the period 1981-2002. J Nat Prods 2003;66:1022-1037.
-
(2003)
J Nat Prods
, vol.66
, pp. 1022-1037
-
-
Newman, D.J.1
Cragg, G.M.2
Snader, K.M.3
-
12
-
-
34247109045
-
Natural products as sources of new drugs over the last 25 years
-
Newman DJ, Cragg GM. Natural products as sources of new drugs over the last 25 years. J Nat Prods 2007;70:461-477.
-
(2007)
J Nat Prods
, vol.70
, pp. 461-477
-
-
Newman, D.J.1
Cragg, G.M.2
-
13
-
-
0031024602
-
Evidence for life on earth more than 3850 million years ago
-
Holland HD. Evidence for life on earth more than 3850 million years ago. Science 1998;275:38-39.
-
(1998)
Science
, vol.275
, pp. 38-39
-
-
Holland, H.D.1
-
14
-
-
0032775330
-
Metabolic engineering of plant secondary metabolite pathways for the production of fine chemicals
-
Verpoorte R, van der Heijden R, ten Hoopen HJG, Memelink J. Metabolic engineering of plant secondary metabolite pathways for the production of fine chemicals. Biotechnol Lett 1999;21:467-479.
-
(1999)
Biotechnol Lett
, vol.21
, pp. 467-479
-
-
Verpoorte, R.1
Van Der Heijden, R.2
Ten Hoopen, H.J.G.3
Memelink, J.4
-
15
-
-
0015241466
-
Angiotensin-converting enzyme inhibitors from the venom of Bothrops jaraca. Isolation, elucidation of structure, and synthesis
-
Ondetti MA, Williams NJ, Sabo EF, Pluscec J, Weaver ER, Kocy O. Angiotensin-converting enzyme inhibitors from the venom of Bothrops jaraca. Isolation, elucidation of structure, and synthesis. Biochemistry 1971;10:4033-4039.
-
(1971)
Biochemistry
, vol.10
, pp. 4033-4039
-
-
Ondetti, M.A.1
Williams, N.J.2
Sabo, E.F.3
Pluscec, J.4
Weaver, E.R.5
Kocy, O.6
-
16
-
-
0037137608
-
Alfred Burger award address in medicinal chemistry. Natural products and design: Interrelated approaches in drug discovery
-
Patchett AA. Alfred Burger award address in medicinal chemistry. Natural products and design: Interrelated approaches in drug discovery. J Med Chem 2002;45:5609-5616.
-
(2002)
J Med Chem
, vol.45
, pp. 5609-5616
-
-
Patchett, A.A.1
-
17
-
-
0007909124
-
Physicians, fads and pharmaceuticals: A history of aspirin
-
Andermann AAJ. Physicians, fads and pharmaceuticals: A history of aspirin. McGill J Med 1996;115-120.
-
(1996)
McGill J Med
, pp. 115-120
-
-
Andermann, A.A.J.1
-
18
-
-
0005632903
-
A century of pain relief
-
Kiefer DM. A century of pain relief. Todays Chem Work 1997;6:38-42.
-
(1997)
Todays Chem Work
, vol.6
, pp. 38-42
-
-
Kiefer, D.M.1
-
19
-
-
70350451130
-
Hoffmann or Eichengrin?
-
Jaffe EE. Hoffmann or Eichengrin? Chem Heritage 2003;21:4.
-
(2003)
Chem Heritage
, vol.21
, pp. 4
-
-
Jaffe, E.E.1
-
20
-
-
25144490320
-
Oceans: Medicine chests of the future?
-
Rayl AJS. Oceans: Medicine chests of the future? Scientist 1999;13:1,4.
-
(1999)
Scientist
, vol.13
, Issue.1
, pp. 4
-
-
Rayl, A.J.S.1
-
21
-
-
0035094686
-
Natural product-based anti-HIV drug discovery and development facilitated by the NCI development therapeutics program
-
Yang SS, Cragg GM, Newman DJ, Bader JP. Natural product-based anti-HIV drug discovery and development facilitated by the NCI development therapeutics program. J Nat Prods 2001;64:265-277.
-
(2001)
J Nat Prods
, vol.64
, pp. 265-277
-
-
Yang, S.S.1
Cragg, G.M.2
Newman, D.J.3
Bader, J.P.4
-
22
-
-
12844274375
-
Antibiotics: Where did we go wrong?
-
Overbye KM, Barrett J. Antibiotics: Where did we go wrong? Drug Disc Today 2005;10:45-52.
-
(2005)
Drug Disc Today
, vol.10
, pp. 45-52
-
-
Overbye, K.M.1
Barrett, J.2
-
23
-
-
0036816873
-
Natural and synthetic substances related to human health
-
Topliss JG, Clark AM, Ernst E, Hufford CD, Johnston GAR, Rimoldi JM, Weimann BJ. Natural and synthetic substances related to human health. Pure Appl Chem 2002;74:1957-1985.
-
(2002)
Pure Appl Chem
, vol.74
, pp. 1957-1985
-
-
Topliss, J.G.1
Clark, A.M.2
Ernst, E.3
Hufford, C.D.4
Johnston, G.A.R.5
Rimoldi, J.M.6
Weimann, B.J.7
-
24
-
-
0034108606
-
Pharmacognosy in the new millennium: Leadfinding and biotechnology
-
Verpoorte R. Pharmacognosy in the new millennium: Lead finding and biotechnology. J. Pharm Pharmacol 2000;52:253-262. (Pubitemid 30189379)
-
(2000)
Journal of Pharmacy and Pharmacology
, vol.52
, Issue.3
, pp. 253-262
-
-
Verpoorte, R.1
-
25
-
-
6444244303
-
Plants and human health in the twenty-first century
-
DOI 10.1016/S0167-7799(02)02080-2, PII S0167779902020802
-
Raskin I, et al. Plants and human health in the twentieth century. Trends Biotechnol 2002;20:522-531. (Pubitemid 35356407)
-
(2002)
Trends in Biotechnology
, vol.20
, Issue.12
, pp. 522-531
-
-
Raskin, I.1
Ribnicky, D.M.2
Komarnytsky, S.3
Ilic, N.4
Poulev, A.5
Borisjuk, N.6
Brinker, A.7
Moreno, D.A.8
Ripoll, C.9
Yakoby, N.10
O'Neal, J.M.11
Cornwell, T.12
Pastor, I.13
Fridlender, B.14
-
26
-
-
80053619289
-
Polyketides: Research increases on modular synthesis of these biomolecules by enzymes
-
Rawls RL. Polyketides: Research increases on modular synthesis of these biomolecules by enzymes. Chem Eng News 1998;76:29-30.
-
(1998)
Chem Eng News
, vol.76
, pp. 29-30
-
-
Rawls, R.L.1
-
27
-
-
0032738419
-
A multiplasmid approach to preparing large libraries of polyketides
-
DOI 10.1073/pnas.96.21.11740
-
Xue Q, Ashley G, Hutchinson CR, Santi DV. A multi-plasmid approach to preparing large libraries of polyketides. Proc Natl Acad Sci USA 1999;96:11740-11745. (Pubitemid 29502802)
-
(1999)
Proceedings of the National Academy of Sciences of the United States of America
, vol.96
, Issue.21
, pp. 11740-11745
-
-
Xue, Q.1
Ashley, G.2
Hutchinson, C.R.3
Santi, D.V.4
-
28
-
-
0028247097
-
The genetics of chemical diversity
-
Cerda-Olmedo E. The genetics of chemical diversity. Crit Revs Microbiol 1994;20:151-160.
-
(1994)
Crit Revs Microbiol
, vol.20
, pp. 151-160
-
-
Cerda-Olmedo, E.1
-
29
-
-
0002090744
-
Fungal gibberellin production
-
Vandamme EJ, editor. London, UK: Elsevier Applied Science
-
Brueckner B, Blechschmidt D, Sembdner G, Schneider G. Fungal gibberellin production. In: Vandamme EJ, editor. Biotechnology of vitamins, pigments and growth factors. London, UK: Elsevier Applied Science; 1989. pp 383-429.
-
(1989)
Biotechnology of Vitamins, Pigments and Growth Factors
, pp. 383-429
-
-
Brueckner, B.1
Blechschmidt, D.2
Sembdner, G.3
Schneider, G.4
-
30
-
-
0001387037
-
The chemistry of gibberellins, an overview
-
Mander LN. The chemistry of gibberellins, an overview. Chem Revs 1992;92:573-612.
-
(1992)
Chem Revs
, vol.92
, pp. 573-612
-
-
Mander, L.N.1
-
32
-
-
2342436107
-
Biotechnological advantages of laboratory-scale solid-state fermentation with fungi
-
DOI 10.1007/s00253-003-1504-3
-
Hölke U, Höfer M, Lenz J. Biotechnical advantages of laboratory-scale solid-state fermentation with fungi. Appl Microbiol Biotechnol 2004;64:175-186. (Pubitemid 38559067)
-
(2004)
Applied Microbiology and Biotechnology
, vol.64
, Issue.2
, pp. 175-186
-
-
Holker, U.1
Hofer, M.2
Lenz, J.3
-
34
-
-
6344275533
-
Recent progress in bioactive metabolites of marine microorganisms
-
Liu X-H, Zhao L-B, She Z-G, Lin YC. Recent progress in bioactive metabolites of marine microorganisms. Chi J Antibiot 2004;29:492-510. (Pubitemid 39390271)
-
(2004)
Chinese Journal of Antibiotics
, vol.29
, Issue.8
, pp. 492-510
-
-
Liu, X.-H.1
Zhao, L.-B.2
She, Z.-G.3
Lin, Y.-C.4
-
35
-
-
9244230571
-
Antitumor polyketide biosynthesis by an uncultivated bacterial symbiont of the marine sponge Theonella swinhoei
-
DOI 10.1073/pnas.0405976101
-
Piel J, Hui D, Wen G, Butzke D, Platzer M, Fusetani N, Matsunaga S. Antitumor polyketide biosynthesis by an uncultivated bacterial symbiont of the marine sponge Theonella swinhoei. Proc Natl Acad Sci USA 2004;101:16222-16227. (Pubitemid 39552826)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.46
, pp. 16222-16227
-
-
Piel, J.1
Hui, D.2
Wen, G.3
Butzke, D.4
Platzer, M.5
Fusetani, N.6
Matsunaga, S.7
-
36
-
-
0036902202
-
Big effects from small changes: Possible ways to explore nature's chemical diversity
-
DOI 10.1002/1439-7633(20020703)3:7<619::AID-CBIC619>3.0.CO;2-9
-
Bode HB, Bethe B, Hofs R, Zeeck A. Big effects from small changes: Possible ways to explore nature's chemical diversity. Chembiochem 2002;3:619-627. (Pubitemid 36004525)
-
(2002)
ChemBioChem
, vol.3
, Issue.7
, pp. 619-627
-
-
Bode, H.B.1
Bethe, B.2
Hofs, R.3
Zeeck, A.4
-
37
-
-
0032784938
-
Cineromycins, -butyrolactones and ansamycins by analysis of the secondary metabolite pattern created by a single strain of Streptomyces
-
Schiewe H-J, Zeeck A. Cineromycins: Butyrolactones and ansamycins of the secondary metabolite pattern created by a single strain of Streptomyces. J Antibiot 1999;52:635-642. (Pubitemid 29378221)
-
(1999)
Journal of Antibiotics
, vol.52
, Issue.7
, pp. 635-642
-
-
Schiewe, H.-J.1
Zeeck, A.2
-
38
-
-
0034903353
-
New natural epothilones from Sorangium cellulosum, strains so ce90/B2 and so ce90/D13: Isolation, structure elucidation, and SAR studies
-
DOI 10.1021/np000629f
-
Hardt IH, Steinmetz H, Gerth K, Sasse F, Reichenbach H, Höfle G. New natural epothilones from Sorangium cellulosum, Strains So ce90/B2 and So ce90/D13: Isolation, structural elucidation, and SAR studies. J Nat Prods 2001;64:847-856. (Pubitemid 32729891)
-
(2001)
Journal of Natural Products
, vol.64
, Issue.7
, pp. 847-856
-
-
Hardt, I.H.1
Steinmetz, H.2
Gerth, K.3
Sasse, F.4
Reichenbach, H.5
Hofle, G.6
-
39
-
-
30744456748
-
Genomic mining for Aspergillus natural products
-
DOI 10.1016/j.chembiol.2005.10.008, PII S1074552105003455
-
Bok JW, Hoffmeister D, Maggio-Hall LA, Murillo R, Glasner JD, Keller NP. Genomic mining for Aspergillus natural products. Chem Biol 2006;13:31-37. (Pubitemid 43099922)
-
(2006)
Chemistry and Biology
, vol.13
, Issue.1
, pp. 31-37
-
-
Bok, J.W.1
Hoffmeister, D.2
Maggio-Hall, L.A.3
Murillo, R.4
Glasner, J.D.5
Keller, N.P.6
-
40
-
-
33645105253
-
Antibiotic-producing ability by representatives of a newly discovered lineage of actinomycetes
-
Busti E, Monciardini P, Cavaletti L, Bamonte R, Lazzarini A, Sosio M, Donadio S. Antibiotic-producing ability by representatives of a newly discovered lineage of actinomycetes. Microbiology 2006;152:675-683.
-
(2006)
Microbiology
, vol.152
, pp. 675-683
-
-
Busti, E.1
Monciardini, P.2
Cavaletti, L.3
Bamonte, R.4
Lazzarini, A.5
Sosio, M.6
Donadio, S.7
-
41
-
-
0032086275
-
Combinatorial biosynthesis of erythromycin and complex polyketides
-
Staunton J. Combinitorial biosynthesis of erythromycin and complex polyketides. Curr Opin Chem Biol 1998;2:339-345. (Pubitemid 128423237)
-
(1998)
Current Opinion in Chemical Biology
, vol.2
, Issue.3
, pp. 339-345
-
-
Staunton, J.1
-
42
-
-
0029739680
-
Natural products as a resource for new drugs
-
DOI 10.1023/A:1016091631721
-
Clark AM. Natural products as a resource for new drugs. Pharmaceut Res 1996;13:1133-1141. (Pubitemid 26279315)
-
(1996)
Pharmaceutical Research
, vol.13
, Issue.8
, pp. 1133-1141
-
-
Clark, A.M.1
-
43
-
-
0002085116
-
Antibiotics from genetically engineered microorganisms
-
Strohl W, editor. 2nd edition. New York: Marcel Dekker
-
Hutchinson CR. Antibiotics from genetically engineered microorganisms. In: Strohl W, editor. Biotechnology of antibiotics, 2nd edition. New York: Marcel Dekker; 1997. pp 683-702.
-
(1997)
Biotechnology of Antibiotics
, pp. 683-702
-
-
Hutchinson, C.R.1
-
44
-
-
0009465938
-
Unnatural natural products by genetic manipulation
-
Sapienza DM, Savage LM, editors. Southborough MA: Internat Bus Comm
-
McAlpine J. Unnatural natural products by genetic manipulation. In: Sapienza DM, Savage LM, editors. Natural products II: New technologies to increase efficiency and speed. Southborough MA: Internat Bus Comm; 1998. pp 251-278.
-
(1998)
Natural Products II: New Technologies to Increase Efficiency and Speed
, pp. 251-278
-
-
McAlpine, J.1
-
45
-
-
0033011422
-
Bacterial transcription factors involved in global regulation
-
DOI 10.1046/j.1365-2958.1999.01445.x
-
Vicente M, Chater K, de Lorenzo V. Bacterial transcription factors involved in global regulation. Molec Microbiol 1999;33:8-17. (Pubitemid 29304184)
-
(1999)
Molecular Microbiology
, vol.33
, Issue.1
, pp. 8-17
-
-
Vicente, M.1
Chater, K.F.2
De Lorenzo, V.3
-
46
-
-
0031981808
-
Santa Rosalia revisited: Why are there so many species of bacteria?
-
Dykhuizen DE. Santa Rosalia revisited: Why are there so many species of bacteria? Ant v Leeuwenhoek 1998;73:25-33.
-
(1998)
Ant V Leeuwenhoek
, vol.73
, pp. 25-33
-
-
Dykhuizen, D.E.1
-
47
-
-
0030497690
-
Total bacterial diversity in soil and sediment communities - A review
-
Torsvik V, Sorheim R, Goksoyr J. Total bacterial diversity in soil and sediment communities - A review. J Indust Microbiol 1996;17:170-178. (Pubitemid 27061875)
-
(1996)
Journal of Industrial Microbiology
, vol.17
, Issue.3-4
, pp. 170-178
-
-
Torsvik, V.1
Sorheim, R.2
Goksoyr, J.3
-
48
-
-
0000238575
-
The success of the hypha and mycelium
-
Gow NAR, Gadd GM, editors. London: Chapman & Hall
-
Carlisle MJ. The success of the hypha and mycelium. In: Gow NAR, Gadd GM, editors. The growing fungus. London: Chapman & Hall;1995. pp 1-18.
-
(1995)
The Growing Fungus
, pp. 1-18
-
-
Carlisle, M.J.1
-
49
-
-
0004152299
-
The fungal dimension of biodiversity: Magnitude, significance, and conservation
-
Hawksworth DL. The fungal dimension of biodiversity: Magnitude, significance, and conservation. Mycol Res 1991;95:641-655.
-
(1991)
Mycol Res
, vol.95
, pp. 641-655
-
-
Hawksworth, D.L.1
-
51
-
-
0030484467
-
Intraspecific diversity in the fungal species Chaunopycnis alba: Implications for microbial screening programs
-
Möller C, Weber G, Dreyfuss MM. Intraspecific diversity in the fungal species Chaunopycnis alba: Implications for microbial screening programs. J Ind Microbiol 1996;17:359-372. (Pubitemid 27064581)
-
(1996)
Journal of Industrial Microbiology
, vol.17
, Issue.5-6
, pp. 359-372
-
-
Moller, C.1
Weber, G.2
Dreyfuss, N.M.3
-
53
-
-
34249811180
-
New aspects of natural products in drug discovery
-
DOI 10.1016/j.tim.2007.04.001, PII S0966842X07000686
-
Lam KS. New aspects of natural products in drug discovery. Trends Microbiol 2007;15:279-289. (Pubitemid 46856162)
-
(2007)
Trends in Microbiology
, vol.15
, Issue.6
, pp. 279-289
-
-
Lam, K.S.1
-
54
-
-
33646818699
-
Antibiotic resistance in bacteria and its future for novel antibiotic development
-
DOI 10.1271/bbb.70.1060
-
Yoneyama H, Katsumata R. Antibiotic resistance in bacteria and its future for novel antibiotic development. Biosci Biotechnol Biochem 2006;70:1060-1075. (Pubitemid 43765235)
-
(2006)
Bioscience, Biotechnology and Biochemistry
, vol.70
, Issue.5
, pp. 1060-1075
-
-
Yoneyama, H.1
Katsumata, R.2
-
55
-
-
7244245763
-
Antibiotics at the crossroads
-
Nathan C. Antibiotics at the crossroads. Nature 2004;431:899-902.
-
(2004)
Nature
, vol.431
, pp. 899-902
-
-
Nathan, C.1
-
56
-
-
0034646538
-
Pathways of discovery: Infectious history
-
Lederberg J. Pathways of discovery: Infectious history. Science 2000;288:287-293.
-
(2000)
Science
, vol.288
, pp. 287-293
-
-
Lederberg, J.1
-
57
-
-
0001899377
-
Industrial antibiotics: Today and the future
-
Strohl W, editor. 2nd edition. NewYork: Marcel Dekker
-
Strohl W. Industrial antibiotics: Today and the future. In: Strohl W, editor. Biotechnology of antibiotics, 2nd edition. NewYork: Marcel Dekker; 1997. pp 1-47.
-
(1997)
Biotechnology of Antibiotics
, pp. 1-47
-
-
Strohl, W.1
-
58
-
-
0035181354
-
Quinolone, everninomycin, glycylcycline, carbapenem, lipopeptide and cephem antibiotics in clinical development
-
Bronson JJ, Barrett JF. Quinolone, everninomycin, glycylcycline, carbapenem, lipopeptide and cephem antibiotics in clinical development. Curr Med Chem 2001;8:1775-1793.
-
(2001)
Curr Med Chem
, vol.8
, pp. 1775-1793
-
-
Bronson, J.J.1
Barrett, J.F.2
-
59
-
-
0343068727
-
Bacteria resistant to drugs draw scrutiny of biofirms
-
19,50,58
-
Erdmann J. Bacteria resistant to drugs draw scrutiny of biofirms. Gen Eng News 1999;19:1,19,50,58.
-
(1999)
Gen Eng News
, vol.19
, pp. 1
-
-
Erdmann, J.1
-
60
-
-
0036792157
-
Antimicrobials: New solutions badly needed
-
Projan SJ, Youngman PJ. Antimicrobials: New solutions badly needed. Curr Opin Microbiol 2002;5:463-465.
-
(2002)
Curr Opin Microbiol
, vol.5
, pp. 463-465
-
-
Projan, S.J.1
Youngman, P.J.2
-
61
-
-
21244462769
-
Plasticity of the Streptomyces genome-evolution and engineering of new antibiotics
-
DOI 10.2174/0929867054367176
-
Hranueli D, Cullum J, Basrak B, Goldstein P, Long PF. Plasticity of the Streptomyces genome-evolution and engineering of new antibiotics. Curr Med Chem 2005;12:1697-1704. (Pubitemid 40895009)
-
(2005)
Current Medicinal Chemistry
, vol.12
, Issue.14
, pp. 1697-1704
-
-
Hranueli, D.1
Cullum, J.2
Basrak, B.3
Goldstein, P.4
Long, P.F.5
-
62
-
-
34047211977
-
Pneumocandin B0 production by fermentation of the fungus Glarea lozoyensis: Physiological and engineering factors affecting titer and structural analogue formation
-
An Z, editor. New York: Marcel Dekker
-
Connors N, Pollard D. Pneumocandin B0 production by fermentation of the fungus Glarea lozoyensis: Physiological and engineering factors affecting titer and structural analogue formation. In: An Z, editor. Handbook of industrial mycology. New York: Marcel Dekker; 2004. pp 515-538.
-
(2004)
Handbook of Industrial Mycology
, pp. 515-538
-
-
Connors, N.1
Pollard, D.2
-
63
-
-
0032173607
-
Antifungals: Mechanism of action and resistance, established and novel drugs
-
Georgopapadakou NH. Antifungals: Mechanism of action and resistance, established and novel drugs. Curr Opin Microbiol 1998;1:547-557.
-
(1998)
Curr Opin Microbiol
, vol.1
, pp. 547-557
-
-
Georgopapadakou, N.H.1
-
64
-
-
0037018165
-
Renewing the fight against bacteria
-
Wilson JF. Renewing the fight against bacteria. Scientist 2002;16:22-23.
-
(2002)
Scientist
, vol.16
, pp. 22-23
-
-
Wilson, J.F.1
-
65
-
-
14744287642
-
Antimicrobials
-
Bull AT, editor. Washington, DC: ASM Press
-
Strohl WR. Antimicrobials. In: Bull AT, editor. Microbial diversity and bioprospecting. Washington, DC: ASM Press; 2004. pp 336-355.
-
(2004)
Microbial Diversity and Bioprospecting
, pp. 336-355
-
-
Strohl, W.R.1
-
66
-
-
0038236925
-
Industrial production of β-lactam antibiotics
-
Elander RP. Industrial production of β-lactam antibiotics. Appl Microbiol Biotechnol 2003;61:385-392.
-
(2003)
Appl Microbiol Biotechnol
, vol.61
, pp. 385-392
-
-
Elander, R.P.1
-
67
-
-
1242322491
-
Winged Helix Transcription Factor CPCR1 Is Involved in Regulation of β-Lactam Biosynthesis in the Fungus Acremonium chrysogenum
-
DOI 10.1128/EC.3.1.121-134.2004
-
Schmitt EK, Bunse A, Janus D, Hoff B, Friedlin E, Kürnsteiner H, Kück U. Winged Helix Transcription factor CPCR1 is involved in regulation of β-lactam biosynthesis in the fungus Acremonium chrysogenum. Eukaryotic Cell 2004;3:121-134. (Pubitemid 38237304)
-
(2004)
Eukaryotic Cell
, vol.3
, Issue.1
, pp. 121-134
-
-
Schmitt, E.K.1
Bunse, A.2
Janus, D.3
Hoff, B.4
Friedlin, E.5
Kurnsteiner, H.6
Kuck, U.7
-
68
-
-
0038449118
-
Continuous cultivations of a Penicillium chrysogenum strain expressing the expandase gene from Streptomyces clavuligerus: Kinetics of adipoyl-7-aminodeacetoxycephalosporanic acid and byproduct formations
-
DOI 10.1002/bit.10678
-
Robin J, Lettier G, McIntyre M, Noorman H, Nielsen J. Continuous cultivations of Penicillium chrysogenum strain expressing the expandase gene from Streptomyces clavuligerus: Growth yields and morphological characterisation. Biotechnol Bioeng 2003;83:353-360. (Pubitemid 36818436)
-
(2003)
Biotechnology and Bioengineering
, vol.83
, Issue.3
, pp. 353-360
-
-
Robin, J.1
Bruheim, P.2
Nielsen, M.L.3
Noorman, H.4
Nielsen, J.5
-
70
-
-
0018343188
-
Thienamycin, a new β-lactam antibiotic. I. Discovery, taxonomy, isolation, and physical properties
-
Kahan FS, Kahan FM, Goegelman RT, Currie SA, Jackson M, Stapley EO, Miller TW, Miller AK, Hendlin D, Mochales S, Hernandez S, Woodruff HB, Birnbaum J. Thienamycin, a new β-lactam antibiotic. I. Discovery, taxonomy, isolation, and physical properties. J Antibiot 3 1979;2:1-12.
-
(1979)
J Antibiot 3
, vol.2
, pp. 1-12
-
-
Kahan, F.S.1
Kahan, F.M.2
Goegelman, R.T.3
Currie, S.A.4
Jackson, M.5
Stapley, E.O.6
Miller, T.W.7
Miller, A.K.8
Hendlin, D.9
Mochales, S.10
Hernandez, S.11
Woodruff, H.B.12
Birnbaum, J.13
-
71
-
-
0027365548
-
Antibiotic-supersusceptible mutants of Escherichia coli and Salmonella typhimurium
-
Vaara M. Antibiotic-supersusceptible mutants of Escherichia coli and Salmonella typhimurium. Antimicrob Agents Chemother 1993;37:2255-2260. (Pubitemid 23324440)
-
(1993)
Antimicrobial Agents and Chemotherapy
, vol.37
, Issue.11
, pp. 2255-2260
-
-
Vaara, M.1
-
72
-
-
0029845913
-
Multidrug efflux pumps of gram-negative bacteria
-
Nikaido H. Multidrug efflux pumps of Gram-negative bacteria. J Bacteriol 1996;178:5819-5853. (Pubitemid 26337766)
-
(1996)
Journal of Bacteriology
, vol.178
, Issue.20
, pp. 5853-5859
-
-
Nikaido, H.1
-
73
-
-
0028314541
-
Multidrug resistance pumps in bacteria: Variations on a theme
-
DOI 10.1016/0968-0004(94)90204-6
-
Lewis K. Multidrug resistance pumps in bacteria: Variations on a theme. TIBS 1994;19:119-123. (Pubitemid 24082789)
-
(1994)
Trends in Biochemical Sciences
, vol.19
, Issue.3
, pp. 119-123
-
-
Lewis, K.1
-
74
-
-
33749260145
-
Genetics of Streptomyces rimosus, the oxytetracycline producer
-
DOI 10.1128/MMBR.00004-06
-
Petkovic H, Cullum J, Hranueli D, Hunter IS, Peric-Concha N, Pigac J, Thamchaipenet A, Vujaklija D, Long PF. Genetics of Streptomyces rimosus, the oxytetracycline producer. Microbiol Mol Biol Rev 2006;70:704-728. (Pubitemid 44484690)
-
(2006)
Microbiology and Molecular Biology Reviews
, vol.70
, Issue.3
, pp. 704-728
-
-
Petkovic, H.1
Cullum, J.2
Hranueli, D.3
Hunter, I.S.4
Peric-Concha, N.5
Pigac, J.6
Thamchaipenet, A.7
Vujaklija, D.8
Long, P.F.9
-
75
-
-
52049126700
-
Production of erythromycin with Saccharopolyspora erythraea
-
Barredo JL, editor. Totowa, NJ: Humana Press
-
Minas W. Production of erythromycin with Saccharopolyspora erythraea. In: Barredo JL, editor. Microbial processes and products. Totowa, NJ: Humana Press; 2004. pp 65-89.
-
(2004)
Microbial Processes and Products
, pp. 65-89
-
-
Minas, W.1
-
76
-
-
4244094004
-
Target directed antimicrobial screens
-
Bu'lock JD, Nisbet LJ, Winstanley DJ, editors. London, UK: Academic Press
-
Fleming ID, Nisbet LJ, Brewer SJ. Target directed antimicrobial screens. In: Bu'lock JD, Nisbet LJ, Winstanley DJ, editors. Bioactive microbial products: Search and discovery. London, UK: Academic Press; 1982. pp 107-130.
-
(1982)
Bioactive Microbial Products: Search and Discovery
, pp. 107-130
-
-
Fleming, I.D.1
Nisbet, L.J.2
Brewer, S.J.3
-
79
-
-
70350443161
-
Applications of fungal ecology in the search for new bioactive natural products
-
Kubicek CP, Druzhinina IS, editors. 2nd edition. New York: Springer
-
Gloer G. Applications of fungal ecology in the search for new bioactive natural products. In: Kubicek CP, Druzhinina IS, editors. The mycota IV environmental and microbial relationships, 2nd edition. New York: Springer; 2007. pp 257-283.
-
(2007)
The Mycota IV Environmental and Microbial Relationships
, pp. 257-283
-
-
Gloer, G.1
-
80
-
-
77956109866
-
Drug discovery: Filtering out failures early in the game
-
Brennan MB. Drug discovery: Filtering out failures early in the game. Chem Eng News 2000;78:63-74.
-
(2000)
Chem Eng News
, vol.78
, pp. 63-74
-
-
Brennan, M.B.1
-
81
-
-
0026380997
-
On the evolution of plant secondary chemical diversity
-
Jones CG, Firn RD. On the evolution of plant secondary chemical diversity. Phil Trans R Soc 1991;333:273-280.
-
(1991)
Phil Trans R Soc
, vol.333
, pp. 273-280
-
-
Jones, C.G.1
Firn, R.D.2
-
82
-
-
0028455313
-
New drug development in the United States from 1963 to 1992
-
DiMasi J, Seibring M, Lasagna L. New drug development in the United States from 1963 to 1992. Clin Pharmacol Ther 1994;55:609-622.
-
(1994)
Clin Pharmacol Ther
, vol.55
, pp. 609-622
-
-
Dimasi, J.1
Seibring, M.2
Lasagna, L.3
-
83
-
-
0035019853
-
Emerging strategies in infectious diseases: New carbapenem and trinem antibacterial agents
-
Sader HS, Gales A. Emerging strategies in infectious diseases: New carbapenem and trinem antibacterial agents. Drugs 2001;61:553-564. (Pubitemid 32453367)
-
(2001)
Drugs
, vol.61
, Issue.5
, pp. 553-564
-
-
Sader, H.S.1
Gales, A.C.2
-
84
-
-
0037526539
-
Getting in tune with the enemy-microbes
-
Lederberg J. Getting in tune with the enemy-microbes. Scientist 2003;17:20-21.
-
(2003)
Scientist
, vol.17
, pp. 20-21
-
-
Lederberg, J.1
-
85
-
-
33644544089
-
Empirical antibacterial drug discovery - Foundation in natural products
-
DOI 10.1016/j.bcp.2005.12.016, PII S0006295205008452, Antibacterials
-
Singh SB, Barrett JF. Empirical antibacterial drug discovery-foundation in natural products. Biochem Pharmacol 2006;71:1006-1015. (Pubitemid 43306793)
-
(2006)
Biochemical Pharmacology
, vol.71
, Issue.7
, pp. 1006-1015
-
-
Singh, S.B.1
Barrett, J.F.2
-
86
-
-
0033399032
-
Emerging diseases: A global threat
-
DaSilva E, Iaccarino M. Emerging diseases: A global threat. Biotech Adv 1999;17:363-384.
-
(1999)
Biotech Adv
, vol.17
, pp. 363-384
-
-
Dasilva, E.1
Iaccarino, M.2
-
87
-
-
0030071463
-
The challenges of emerging infectious diseases
-
Tenover FC, Hughes JM. The challenges of emerging infectious diseases. J Amer Med Assoc 1996;275:300-304.
-
(1996)
J Amer Med Assoc
, vol.275
, pp. 300-304
-
-
Tenover, F.C.1
Hughes, J.M.2
-
88
-
-
4444317005
-
Cycling antibiotics may not be good for your health
-
Levin BR, Bonten MJM. Cycling antibiotics may not be good for your health. Proc Natl Acad Sci USA 2004;101:13101-13102.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 13101-13102
-
-
Levin, B.R.1
Bonten, M.J.M.2
-
89
-
-
25844528216
-
Barriers on the road to new antibiotics
-
Balaban N, Dell'Acqua G. Barriers on the road to new antibiotics. Scientist 2005;19:42-43.
-
(2005)
Scientist
, vol.19
, pp. 42-43
-
-
Balaban, N.1
Dell'Acqua, G.2
-
90
-
-
4344632132
-
Debaffling biofilms
-
Johnston N. Debaffling biofilms. Scientist 2004;18:34-35.
-
(2004)
Scientist
, vol.18
, pp. 34-35
-
-
Johnston, N.1
-
91
-
-
0036157549
-
Pseudomonas aeruginosa displays multiple phenotypes during development as a biofilm
-
DOI 10.1128/jb.184.4.1140-1154.2002
-
Sauer K, Camper AK, Garth D, Ehrlich D, Costerton JW, Davies DG. Pseudomonas aeruginosa displays multiple phenotypes during development as a biofilm. J Bacteriol 2002;184:1140-1154. (Pubitemid 34113383)
-
(2002)
Journal of Bacteriology
, vol.184
, Issue.4
, pp. 1140-1154
-
-
Sauer, K.1
Camper, A.K.2
Ehrlich, G.D.3
Costerton, J.W.4
Davies, D.G.5
-
92
-
-
0030848819
-
Bacterial protein secretion - A target for new antibiotics?
-
Stephens C, Shapiro L. Bacterial protein secretion - A target for new antibiotics? Chem Biol 1997;4:637-641.
-
(1997)
Chem Biol
, vol.4
, pp. 637-641
-
-
Stephens, C.1
Shapiro, L.2
-
93
-
-
0029796373
-
New directions in antibacterial research
-
Chu DT, Plattner JJ, Katz L. New directions in antibacterial research. J Med Chem 1996;39:3853-3874.
-
(1996)
J Med Chem
, vol.39
, pp. 3853-3874
-
-
Chu, D.T.1
Plattner, J.J.2
Katz, L.3
-
95
-
-
84944656315
-
Emergence of drug-resistant pneumococcal infections in the United States
-
DOI 10.1001/jama.271.23.1831
-
Breiman R, Butler J, Tenover F, Elliot J, Facklam R. Emergence of drug-resistant pneumococcal infections in the United States. J Amer Med Assoc 1994;271:1831-1835. (Pubitemid 24169696)
-
(1994)
Journal of the American Medical Association
, vol.271
, Issue.23
, pp. 1831-1835
-
-
Breiman, R.F.1
Butler, J.C.2
Tenover, F.C.3
Elliott, J.A.4
Facklam, R.R.5
-
96
-
-
0030031423
-
Strategies to prevent and control the emergence and spread of antimicrobial-resistant microorganisms in hospitals
-
Goldman DA, Weinstein RA, Wenzel RP, Tablan OC, Duma RJ, Gaynes RP, Schlosser J, Martone WJ. Strategies to prevent and control the emergence and spread of antimicrobial-resistant microorganisms in hospitals. J Amer Med Assoc 1996;275:234-240.
-
(1996)
J Amer Med Assoc
, vol.275
, pp. 234-240
-
-
Goldman, D.A.1
Weinstein, R.A.2
Wenzel, R.P.3
Tablan, O.C.4
Duma, R.J.5
Gaynes, R.P.6
Schlosser, J.7
Martone, W.J.8
-
98
-
-
0030903151
-
Resistance to glycopeptides in enterococci
-
Leclercq R, Courvalin P. Resistance to glycopeptides in enterococci. Clin Inf Dis 1997;24:545-555.
-
(1997)
Clin Inf Dis
, vol.24
, pp. 545-555
-
-
Leclercq, R.1
Courvalin, P.2
-
100
-
-
0026517065
-
Pharmakinetics of teicoplanin upon multiple dose administration to normal healthy male volunteers
-
Thompson GA, Smith JA, Kenny MT, Dulwoeth JK, Kulmala HK, Yuh L. Pharmakinetics of teicoplanin upon multiple dose administration to normal healthy male volunteers. Biopharm Drug Dispos 1992;33:213-220.
-
(1992)
Biopharm Drug Dispos
, vol.33
, pp. 213-220
-
-
Thompson, G.A.1
Smith, J.A.2
Kenny, M.T.3
Dulwoeth, J.K.4
Kulmala, H.K.5
Yuh, L.6
-
101
-
-
0029947613
-
The comparative efficacy and safety of teicoplanin and vancomycin
-
DOI 10.1093/jac/37.2.209
-
Wood MJ. The comparative efficacy and safety of teicoplanin and vancomycin. J Antimicrob Chemother 1996;37:209-222. (Pubitemid 26123160)
-
(1996)
Journal of Antimicrobial Chemotherapy
, vol.37
, Issue.2
, pp. 209-222
-
-
Wood, M.J.1
-
102
-
-
10944272743
-
Antibacterial resistance worldwide: Causes, challenges and responses
-
DOI 10.1038/nm1145
-
Levy SB, Marshall B. Antibacterial resistance worldwide: Causes, challenges and responses. Nat Med Suppl 2004;10:S122-S129. (Pubitemid 40018235)
-
(2004)
Nature Medicine
, vol.10
, Issue.12 SUPPL.
-
-
Levy, S.B.1
Marshall, B.2
-
103
-
-
3042658714
-
Hydrophobic vancomycin derivatives with improved ADME properties: Discovery of telavancin (TD-6424)
-
Leadbetter MR, et al. Hydrophobic vancomycin derivatives with improved ADME properties: Discovery of telavancin (TD-6424). J Antibiot 2004;57:326-336.
-
(2004)
J Antibiot
, vol.57
, pp. 326-336
-
-
Leadbetter, M.R.1
-
104
-
-
0038041952
-
Vancomycin resistance: Occurrence, mechanisms and strategies to combat it
-
DOI 10.1517/14728222.7.3.311
-
Boneca IG, Chios G. Vancomycin resistance: Occurrence, mechanisms and strategies to combat it. Expert Opin Ther Targets 2003;7:311-328. (Pubitemid 36722218)
-
(2003)
Expert Opinion on Therapeutic Targets
, vol.7
, Issue.3
, pp. 311-328
-
-
Boneca, I.G.1
Chiosis, G.2
-
105
-
-
34248207301
-
Review of dalbavancin, a novel semisynthetic lipoglycopeptide
-
DOI 10.1517/13543784.16.5.717
-
Kim A, Kuti JL, Nicolau DP. Review of dalbavancin, a novel semisynthetic lipoglycopeptide. Expert Opin Invest Drugs 2007;16:717-733. (Pubitemid 46723274)
-
(2007)
Expert Opinion on Investigational Drugs
, vol.16
, Issue.5
, pp. 717-733
-
-
Kim, A.1
Kuti, J.L.2
Nicolau, D.P.3
-
106
-
-
0034123845
-
Resisting resistance: New chemical strategies for battling superbugs
-
Wright GD. Resisting resistance: New chemical strategies for battling superbugs. Chem Biol 2000;7:R127-R132.
-
(2000)
Chem Biol
, vol.7
-
-
Wright, G.D.1
-
107
-
-
0034652383
-
Synergy in a medicinal plant: Antimicrobial action of berberine potentiated by 5'-methoxyhydnocarpin, a multidrug pump inhibitor
-
DOI 10.1073/pnas.030540597
-
Stermitz FR, Lorenz P, Tawara JN, Zenewicz LA, Lewis K. Synergy in a medicinal plant: Antimicrobial action of berberine potentiated by 50-methoxyhydrocarpin, a multidrug pump inhibitor. Proc Natl Acad Sci USA 2000;97:1433-1437. (Pubitemid 30118458)
-
(2000)
Proceedings of the National Academy of Sciences of the United States of America
, vol.97
, Issue.4
, pp. 1433-1437
-
-
Stermitz, F.R.1
Lorenz, P.2
Tawara, J.N.3
Zenewicz, L.A.4
Lewis, K.5
-
108
-
-
33845894155
-
Multi-targeting by monotherapeutic antibacterials
-
Silver LL. Multi-targeting by monotherapeutic antibacterials. Nature Revs Drug Disc 2007;6:41-55.
-
(2007)
Nature Revs Drug Disc
, vol.6
, pp. 41-55
-
-
Silver, L.L.1
-
109
-
-
0016378451
-
Recent developments of antibiotic research and classification of antibiotics according to chemical structure
-
Berdy J. Recent developments of antibiotic research and classification of antibiotics according to chemical structure. Adv Appl Microbiol 1974;18:309-406.
-
(1974)
Adv Appl Microbiol
, vol.18
, pp. 309-406
-
-
Berdy, J.1
-
110
-
-
0031946077
-
Recent developments in streptogramin research
-
Barriere JC, Berthaud N, Beyer D, Dutka-Malen S, Paris JM, Desnottes JF. Recent developments in streptogramin research. Curr Pharm Des 1998;4:155-180.
-
(1998)
Curr Pharm des
, vol.4
, pp. 155-180
-
-
Barriere, J.C.1
Berthaud, N.2
Beyer, D.3
Dutka-Malen, S.4
Paris, J.M.5
Desnottes, J.F.6
-
111
-
-
0029871331
-
RP 59500, a streptogramin derivative, is effective in murine listeriosis
-
Nichterlein T, Kretschmar M, Hof H. RP 59500, a streptogramin derivative, is effective in murine listerosis. J Chemother 1996;8:107-112. (Pubitemid 26127819)
-
(1996)
Journal of Chemotherapy
, vol.8
, Issue.2
, pp. 107-112
-
-
Nichterlein, T.1
Kretschmar, M.2
Hof, H.3
-
112
-
-
0032861705
-
Quinupristin/dalfopristin: Therapeutic potential for vancomycin-resistant enterococcal infections
-
Moellering RC. Quinupristin/dalfopristin: Therapeutic potential for vancomycin-resistant enterococcal infections. J Antimicrob Chemother 1999;44:25-30.
-
(1999)
J Antimicrob Chemother
, vol.44
, pp. 25-30
-
-
Moellering, R.C.1
-
113
-
-
0032795631
-
The efficacy and safety of quinupristin/dalfopristin for the treatment of infections caused by vancomycin-resistant Enterococcus faecium
-
DOI 10.1093/jac/44.2.251
-
Moellering RC, Linden PK, Reinhardt J, Blumberg EA, Bompart F, Talbot GH. The efficacy and safety of quinupristin/dalfopristin for the treatment of infections caused by vancomycin-resistant Enterococcus faecium. J Antimicrob Chemother 1999;44:251-261. (Pubitemid 29389289)
-
(1999)
Journal of Antimicrobial Chemotherapy
, vol.44
, Issue.2
, pp. 251-261
-
-
Moellering, R.C.1
Linden, P.K.2
Reinhardt, J.3
Blumberg, E.A.4
Bompart, F.5
Talbot, G.H.6
-
114
-
-
33751156911
-
Drug firms restock antibacterial arsenal
-
Stinson SC. Drug firms restock antibacterial arsenal. Chem & Eng News 1996;74:75-100.
-
(1996)
Chem & Eng News
, vol.74
, pp. 75-100
-
-
Stinson, S.C.1
-
115
-
-
0033833040
-
Quinopristin/dalfopristin and linezolid: Where, when, which and whether to use?
-
Livermore DM. Quinopristin/dalfopristin and linezolid: Where, when, which and whether to use? J Antimicrob Chemother 2000;46:347-350.
-
(2000)
J Antimicrob Chemother
, vol.46
, pp. 347-350
-
-
Livermore, D.M.1
-
116
-
-
2042510935
-
FDA approves the antibiotic Synercid for limited clinical uses
-
Cimons M. FDA approves the antibiotic Synercid for limited clinical uses. ASM News 1999;65:800-801.
-
(1999)
ASM News
, vol.65
, pp. 800-801
-
-
Cimons, M.1
-
117
-
-
0031954469
-
Recent developments in tetracycline antibiotics
-
Sum P-E, Sum F-W, Projan SJ. Recent developments in tetracycline antibiotics. Curr Pharm Des 1998;4:119-132.
-
(1998)
Curr Pharm des
, vol.4
, pp. 119-132
-
-
Sum, P.-E.1
Sum, F.-W.2
Projan, S.J.3
-
118
-
-
0032918653
-
In vitro and in vivo antibacterial activities of a novel glycylcycline, the 9-t-butylglycylamido derivative of minocycline (GAR-936)
-
Petersen PJ, Jacobus NV, Weiss WJ, Sum PE, Testa RT. In vitro and in vivo antibacterial activities of a novel glycylcycline, the 9-t-butylglycylamido derivative of minocycline (GAR-936). Antimicrob Agents Chemother 1999;43:738-744.
-
(1999)
Antimicrob Agents Chemother
, vol.43
, pp. 738-744
-
-
Petersen, P.J.1
Jacobus, N.V.2
Weiss, W.J.3
Sum, P.E.4
Testa, R.T.5
-
119
-
-
27144457701
-
Tigecycline: What is it, and where should it be used?
-
Livermore DM. Tigecycline: What is it, and where should it be used? J Antimicrob Chemother 2005;56:611-614.
-
(2005)
J Antimicrob Chemother
, vol.56
, pp. 611-614
-
-
Livermore, D.M.1
-
121
-
-
0038647766
-
Recent progress in the field of macrolide antibiotics
-
DOI 10.1517/13543776.13.6.787
-
Henninger TC. Recent progress in the field of macrolide antibiotics. Expert Opin Ther Patents 2003;13:787-805. (Pubitemid 36748944)
-
(2003)
Expert Opinion on Therapeutic Patents
, vol.13
, Issue.6
, pp. 787-805
-
-
Henninger, T.C.1
-
122
-
-
15644366975
-
Synthesis and antibacterial activity of ketolides (6-O-methyl-3- Oxoerythromycin derivatives): A new class of antibacterials highly potent against macrolide-resistant and -susceptible respiratory pathogens
-
DOI 10.1021/jm980240d
-
Agouridas C, Denis A, Auger J-M, Benedetti Y, Bonnefoy A, Bretin F, Chantot J-F, Dussarat A, Fromentin C, Gouin D'Ambrieres S, Lachaud S, Laurin P, Le Martret O, Loyau V, Tessit N. Synthesis and antibacterial activity of ketolides (6-O-methyl-3-oxoerythromycin derivatives): A new class of antibacterials highly potent against macrolide-resistant and -susceptible respiratory pathogens. J Med Chem 1998;41:4080-4100. (Pubitemid 28483484)
-
(1998)
Journal of Medicinal Chemistry
, vol.41
, Issue.21
, pp. 4080-4100
-
-
Agouridas, C.1
Denis, A.2
Auger, J.-M.3
Benedetti, Y.4
Bonnefoy, A.5
Bretin, F.6
Chantot, J.-F.7
Dussarat, A.8
Fromentin, C.9
D'Ambrieres, S.G.10
Lachaud, S.11
Laurin, P.12
Martret, O.L.13
Loyau, V.14
Tessot, N.15
-
124
-
-
0035150376
-
Telithromycin: A new ketolide antimicrobial for treatment of respiratory tract infections
-
DOI 10.1517/13543784.10.2.353
-
Yassin HM, Dever LL. Telithromycin: A new ketolide antimicrobial for treatment of respiratory tract infections. Expert Opin Invest Drugs 2001;10:353-367. (Pubitemid 32117943)
-
(2001)
Expert Opinion on Investigational Drugs
, vol.10
, Issue.2
, pp. 353-367
-
-
Yassin, H.M.1
Dever, L.L.2
-
125
-
-
0033229837
-
Synthesis and antibacterial activity of HMR 3647 a new ketolide highly potent against erythromycin-resistant and susceptible pathogens
-
DOI 10.1016/S0960-894X(99)00534-X, PII S0960894X9900534X
-
Denis A, Agouridas C, Auger J-M, Benedetti Y, Bonnefoy A, Bretin F, Chantot J-F, Dussarat A, Fromentin C, Gouin D'Ambrieres S, Lachaud S, Laurin P, Le Martret O, Loyau V, Tessit N, Pejac J-M, Perron S. Synthesis and antibacterial activity of HMR 3647, a new ketolide highly potent against erythromycin-resistant and susceptible pathogens. Bioorg Med Chem Lett 1999;9:3075-3080. (Pubitemid 29515385)
-
(1999)
Bioorganic and Medicinal Chemistry Letters
, vol.9
, Issue.21
, pp. 3075-3080
-
-
Denis, A.1
Agouridas, C.2
Auger, J.-M.3
Benedetti, Y.4
Bonnefoy, A.5
Bretin, F.6
Chantot, J.-F.7
Dussarat, A.8
Fromentin, C.9
Gouin D'Ambrieres, S.10
Lachaud, S.11
Laurin, P.12
Le Martret, O.13
Loyau, V.14
Tessot, N.15
Pejac, J.-M.16
Perron, S.17
-
126
-
-
0034752380
-
Overcoming antimicrobial resistance: Profile of a new ketolide antibacterial, telithromycin
-
Leclercq R. Overcoming antimicrobial resistance: Profile of a new ketolide antibacterial, telithromycin. J Antimicrob Chemother 2001;48:9-23. (Pubitemid 33040683)
-
(2001)
Journal of Antimicrobial Chemotherapy
, vol.48
, Issue.TOPIC T1
, pp. 9-23
-
-
Leclercq, R.1
-
127
-
-
0033847734
-
The millennium bugs - The need for and development of new antibacterials
-
DOI 10.1016/S0924-8579(00)00189-8, PII S0924857900001898
-
Bax R, Mullan N, Verhoef J. The millennium bugs - the need for and development of new antibacterials. J Antimicrob Agents 2000;16:51-59. (Pubitemid 30665425)
-
(2000)
International Journal of Antimicrobial Agents
, vol.16
, Issue.1
, pp. 51-59
-
-
Bax, R.1
Mullan, N.2
Verhoef, J.3
-
128
-
-
0009528292
-
Polyketide system cloned, characterized
-
Borman S. Polyketide system cloned, characterized. Chem Eng News 1998;76:27-28.
-
(1998)
Chem Eng News
, vol.76
, pp. 27-28
-
-
Borman, S.1
-
129
-
-
33644552115
-
Efflux systems in bacterial pathogens: An opportunity for therapeutic intervention? An industry view
-
Lynch AS. Efflux systems in bacterial pathogens: An opportunity for therapeutic intervention? An industry view. Biochem Pharamacol 2006;71:949-956.
-
(2006)
Biochem Pharamacol
, vol.71
, pp. 949-956
-
-
Lynch, A.S.1
-
130
-
-
0032846315
-
Daptomycin: A novel agent for Gram-positive infections
-
DOI 10.1517/13543784.8.8.1223
-
Tally FP, Zeckel M, Wasilewski MM, Carini C, Berman CL, Drusano GL, Oleson Jr FB. Daptomycin: A novel agent for gram-positive infections. Expert Opin Invest Drugs 1999;8:1223-1238. (Pubitemid 29410579)
-
(1999)
Expert Opinion on Investigational Drugs
, vol.8
, Issue.8
, pp. 1223-1238
-
-
Tally, F.P.1
Zeckel, M.2
Wasilewski, M.M.3
Carini, C.4
Berman, C.L.5
Drusano, G.L.6
Oleson Jr., F.B.7
-
131
-
-
29244459093
-
Natural products to drugs: Daptomycin and related lipopeptide antibiotics
-
DOI 10.1039/b416648p
-
Baltz RH, Miao V, Wrigley SK. Natural products to drugs: Daptomycin and related lipopeptide antibiotics. Nat Prod Rep 2005;22:717-741. (Pubitemid 41830839)
-
(2005)
Natural Product Reports
, vol.22
, Issue.6
, pp. 717-741
-
-
Baltz, R.H.1
Miao, V.2
Wrigley, S.K.3
-
132
-
-
4544230403
-
Lipopeptides, focusing on daptomycin, for the treatment of Gram-positive infections
-
DOI 10.1517/13543784.13.9.1159
-
Eisenstein BI. Lipopeptides, focusing on daptomycin, for the treatment of Gram-positive infections. Expert Opin Invest Drugs 2004;13:1159-1169. (Pubitemid 39242739)
-
(2004)
Expert Opinion on Investigational Drugs
, vol.13
, Issue.9
, pp. 1159-1169
-
-
Eisenstein, B.I.1
-
134
-
-
70350452327
-
Amphomycin and its production and recovery
-
US Patent 3,126,317. Filed November 20, 1958. Published March 24, 1964
-
Heinemann B, Kaplan MA, Hooper IR. Amphomycin and its production and recovery. US Patent 3,126,317. Filed November 20, 1958. Published March 24, 1964.
-
-
-
Heinemann, B.1
Kaplan, M.A.2
Hooper, I.R.3
-
136
-
-
0033574743
-
Vancomycin derivatives that inhibit peptidoglycan biosynthesis without binding D-Ala-D-Ala
-
DOI 10.1126/science.284.5413.507
-
Ge M, Chen Z, Russell HO, Kohler J, Silver LL, Kerns R, Fukuzawa S, Thompson C, Kahne D. Vancomycin derivatives that inhibit peptidoglycan biosynthesis without binding D-Ala-D-Ala. Science 1999;284:507-511. (Pubitemid 29289628)
-
(1999)
Science
, vol.284
, Issue.5413
, pp. 507-511
-
-
Ge, M.1
Chen, Z.2
Onishi, H.R.3
Kohler, J.4
Silver, L.L.5
Kerns, R.6
Fukuzawa, S.7
Thompson, C.8
Kahne, D.9
-
137
-
-
0033574766
-
Deconstructing vancomycin
-
Walsh C. Deconstructing vancomycin. Science 1999;284:442-443.
-
(1999)
Science
, vol.284
, pp. 442-443
-
-
Walsh, C.1
-
138
-
-
0024596334
-
Ramoplanin (A-16686), a new glycolipodepsipeptide antibiotic. III. Structure elucidation
-
Ciabatti R, Kettenring JK, Winters G, Tuan G, Zerilli L, Cavalleri B. Ramoplanin (A-16686), a new glycolipodepsipeptide antibiotic. III. Structure elucidation. J Antibiot 1989;41:254-267. (Pubitemid 19068323)
-
(1989)
Journal of Antibiotics
, vol.42
, Issue.2
, pp. 254-267
-
-
Ciabatti, R.1
Kettenring, J.K.2
Winters, G.3
Tuan, G.4
Zerilli, L.5
Cavalleri, B.6
-
139
-
-
0021233768
-
A-16686, a new antibiotic from Actinoplanes. I. Fermentation, isolation and preliminary physiochemical characteristics
-
Cavalleri B, Pagani H, Volpe G, Selva E, Parenti F. A-16686, a new antibiotic from Actinoplanes. I. Fermentation, isolation and preliminary physiochemical characteristics. J Antibiot 1984;37:309-317.
-
(1984)
J Antibiot
, vol.37
, pp. 309-317
-
-
Cavalleri, B.1
Pagani, H.2
Volpe, G.3
Selva, E.4
Parenti, F.5
-
140
-
-
0037093942
-
Total synthesis of the ramoplanin A2 and ramoplanose aglycon
-
DOI 10.1021/ja020237q
-
Jiang W, Wanner J, Lee RJ, Bounaud P-Y, Boger DL. Total synthesis of the ramoplanin A2 and ramoplanose aglycon. J Amer Chem Soc 2002;124:5288-5290. (Pubitemid 34506924)
-
(2002)
Journal of the American Chemical Society
, vol.124
, Issue.19
, pp. 5288-5290
-
-
Jiang, W.1
Wanner, J.2
Lee, R.J.3
Bounaud, P.-Y.4
Boger, D.L.5
-
141
-
-
0036669208
-
Functional Analysis of the Lipoglycodepsipeptide Antibiotic Ramoplanin
-
DOI 10.1016/S1074-5521(02)00191-6, PII S1074552102001916
-
Cudic P, Behenna DC, Kranz JK, Kruger RG, Wand AJ, Veklich YI, Weisel JW, McCafferty DG. Functional analysis of lipoglycodepsipeptide antibiotic ramoplanin. Chem Biol 2002;9:897-906. (Pubitemid 35240909)
-
(2002)
Chemistry and Biology
, vol.9
, Issue.8
, pp. 897-906
-
-
Cudic, P.1
Behenna, D.C.2
Kranz, J.K.3
Kruger, R.G.4
Wand, A.J.5
Veklich, Y.I.6
Weisel, J.W.7
McCafferty, D.G.8
-
142
-
-
0037115316
-
Linezolid: An oxazolidinone antibacterial agent
-
Paladino JA. Linezolid: An oxazolidinone antibacterial agent. Amer J Health Syst Pharm 2002;59:2413-2425.
-
(2002)
Amer J Health Syst Pharm
, vol.59
, pp. 2413-2425
-
-
Paladino, J.A.1
-
143
-
-
70350464668
-
New directions in drug discovery
-
36,56,66,80
-
Fox S, Farr-Jones S, Yund MA. New directions in drug discovery. Gen Eng News 1999;19:10,36,56,66,80.
-
(1999)
Gen Eng News
, vol.19
, pp. 10
-
-
Fox, S.1
Farr-Jones, S.2
Yund, M.A.3
-
145
-
-
0034058145
-
Oxazolidinones: A review
-
Diekema DJ, Jones RN. Oxazolidinones: A review. Drugs 2000;59:7-16.
-
(2000)
Drugs
, vol.59
, pp. 7-16
-
-
Diekema, D.J.1
Jones, R.N.2
-
147
-
-
0000334044
-
Antifungal drug resistance in Candida albicans
-
White TC. Antifungal drug resistance in Candida albicans. ASM News 1997;63:427-433.
-
(1997)
ASM News
, vol.63
, pp. 427-433
-
-
White, T.C.1
-
148
-
-
0030722130
-
Antifungal resistance trends towards the year 2000. Implications for therapy and new approaches
-
Alexander BP, Perfect JR. Antifungal resistance trends towards the year 2000. Implications for therapy and new approaches. Drugs 1997;54:657-678.
-
(1997)
Drugs
, vol.54
, pp. 657-678
-
-
Alexander, B.P.1
Perfect, J.R.2
-
149
-
-
0032832199
-
Novel antifungal drugs
-
DiDomenico B. Novel antifungal drugs. Curr Opin Microbiol 1999;2:509-515.
-
(1999)
Curr Opin Microbiol
, vol.2
, pp. 509-515
-
-
Didomenico, B.1
-
150
-
-
0027067809
-
Pneumocandins from Zalerion arboricola I. Discovery and isolation
-
Schwartz RE, Sesin DF, Joshua H, Wilson KE, Kempf AJ, Goklen KA, Kuehner D, Gailliot P, Gleason C, White R, Inamine E, Bills G, Salmon P, Zitano L. Pneumocandins from Zalerion arboricola I. Discovery and isolation. J Antibiot 1992;45:1853-1866. (Pubitemid 23059697)
-
(1992)
Journal of Antibiotics
, vol.45
, Issue.12
, pp. 1853-1866
-
-
Schwartz, R.E.1
Sesin, D.F.2
Joshua, H.3
Wilson, K.E.4
Kempf, A.J.5
Goklen, K.A.6
Kuehner, D.7
Gailliot, P.8
Gleason, C.9
White, R.10
Inamine, E.11
Bills, G.12
Salmon, P.13
Zitano, L.14
-
151
-
-
0002711804
-
New antifungal drug targets: A vision for the future
-
Kurtz MB. New antifungal drug targets: A vision for the future. ASM News 1998;64:31-39.
-
(1998)
ASM News
, vol.64
, pp. 31-39
-
-
Kurtz, M.B.1
-
152
-
-
0035397313
-
Caspofungin acetate: An antifungal agent
-
Hoang AT. Caspofungin acetate: An antifungal agent. Amer J Health-Syst Pharm 2001;58:1206-1214.
-
(2001)
Amer J Health-Syst Pharm
, vol.58
, pp. 1206-1214
-
-
Hoang, A.T.1
-
153
-
-
0035147071
-
Update on antifungals targeted to the cell wall: Focus on β-1,3-glucan synthase inhibitors
-
Georgopapadakou NH. Update on antifungals targeted to the cell wall: Focus on β-1,3-glucan synthase inhibitors. Expert Opin Invest Drugs 2001;10:269-280.
-
(2001)
Expert Opin Invest Drugs
, vol.10
, pp. 269-280
-
-
Georgopapadakou, N.H.1
-
154
-
-
0028000948
-
The echinocandins: Antifungals targeted to the fungal cell wall
-
Debono M. The echinocandins: Antifungals targeted to the fungal cell wall. Expert Opin Invest Drugs 1994;3:821-829. (Pubitemid 24247049)
-
(1994)
Expert Opinion on Investigational Drugs
, vol.3
, Issue.8
, pp. 821-829
-
-
Debono, M.1
|