Pentoxifylline prevents loss of PP2A phosphatase activity and recruitment of histone acetyltransferases to proinflammatory genes in acute pancreatitis

Journal of Pharmacology and Experimental Therapeutics

Volumn 331, Issue 2, 2009, Pages 609-617

  Sandoval, Juan ^a   Escobar, Javier ^a   Pereda, Javier ^a   Sacilotto, Natalia ^a   Rodriguez, José Luis ^a   Sabater, Luis ^b   Aparisi, Luis ^b   Franco, Luis ^a   López Rodas, Gerardo ^a   Sastre, Juan ^a  

^a UNIVERSITY OF VALENCIA   (Spain)

^b HOSPITAL CLÍNICO UNIVERSITARIO   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 3; CALCINEURIN; CCAAT ENHANCER BINDING PROTEIN BETA; CYCLIC AMP; EARLY GROWTH RESPONSE FACTOR 1; HISTONE ACETYLTRANSFERASE; HISTONE DEACETYLASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE KINASE 2; PENTOXIFYLLINE; PHOSPHODIESTERASE INHIBITOR; PHOSPHOPROTEIN PHOSPHATASE 2A; PROTEIN SERINE THREONINE KINASE; TAUROCHOLIC ACID; TRANSCRIPTION FACTOR; TUMOR NECROSIS FACTOR ALPHA;

ACINAR CELL; ACUTE HEMORRHAGIC PANCREATITIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; GENE EXPRESSION REGULATION; GENE INDUCTION; MALE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION;

ACUTE DISEASE; ANIMALS; ANTI-INFLAMMATORY AGENTS; BLOTTING, WESTERN; CELL LINE; CHROMATIN IMMUNOPRECIPITATION; CYCLIC AMP; CYCLIC NUCLEOTIDE PHOSPHODIESTERASES, TYPE 2; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HISTONE ACETYLTRANSFERASES; INFLAMMATION; MALE; MITOGEN-ACTIVATED PROTEIN KINASES; PANCREATITIS; PENTOXIFYLLINE; PHOSPHODIESTERASE INHIBITORS; PHOSPHOPROTEIN PHOSPHATASES; RATS; RATS, WISTAR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA; TUMOR NECROSIS FACTOR-ALPHA;

EID: 70350445533     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.109.157537     Document Type: Article

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