Monoclonal antibodies against the connexin43-interacting protein CIP85

Hybridoma

Volumn 28, Issue 5, 2009, Pages 355-361

  Cochrane, Kimberly ^a,b   Berestecky, John M ^c   Kitamura, Carolynn ^a   Lau, Alan F ^a,b  

^a UNIVERSITY OF HAWAII CANCER CENTER   (United States)

^b UNIVERSITY OF HAWAII   (United States)

^c Kapiolani Community College   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CONNEXIN 43; CONNEXIN 43 INTERACTING PROTEIN; MONOCLONAL ANTIBODY; PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ARTICLE; CELL MEMBRANE; CELL STRAIN; CELL STRAIN COS7; CELL STRAIN HEK293; CONTROLLED STUDY; ENDOCYTOSIS; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GAP JUNCTION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; HYBRIDOMA; IMMUNOBLOTTING; IMMUNOFLUORESCENCE MICROSCOPY; IMMUNOPRECIPITATION; LYSOSOME; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SPLEEN CELL;

ANIMALS; ANTIBODIES, MONOCLONAL; BLOTTING, WESTERN; ENZYME-LINKED IMMUNOSORBENT ASSAY; HELA CELLS; HUMANS; IMMUNOPRECIPITATION; MICE; MICE, INBRED BALB C; MICROSCOPY, CONFOCAL; MICROSCOPY, FLUORESCENCE; RAB GTP-BINDING PROTEINS;

EID: 70350436111     PISSN: 15540014     EISSN: None     Source Type: Journal    
DOI: 10.1089/hyb.2009.0033     Document Type: Article

References (25)

1. Vinken M, Vanhaecke T, Papeleu P, Snykers S, Henkens T, and Rogiers V: Connexins and their channels in cell growth and cell death. Cell Signal 2006;18:592-600.
2. Wei CJ, Xu X, and Lo CW: Connexins and cell signaling in development and disease. Annu Rev Cell Dev Biol 2004;20: 811-838.
3. Goodenough DA, Goliger JA, and Paul DL: Connexins, connexons, and intercellular communication. Annu Rev Biochem 1996;65:475-502.
4. Iacobas DA, Scemes E, and Spray DC: Gene expression alterations in connexin null mice extend beyond the gap junction. Neurochem Int 2004;45:243-250.
5. Jin C, and Lau AF: Characterization of a Novel SH3- containing Protein that May Interact with Connexin43. IOS Press, Amsterdam, 1998.
6. Jin C, Lau AF, and Martyn KD: Identification of connexininteracting proteins: application of the yeast two-hybrid screen. Methods 2000;20:219-231.
7. Yang H, Sasaki T, Minoshima S, and Shimizu N: Identifi- cation of three novel proteins (SGSM1, 2, 3) which modulate small G protein (RAP and RAB)-mediated signaling pathway. Genomics 2007;90:249-260.
8. Lupas A: Prediction and analysis of coiled-coil structures. Methods Enzymol 1996;266:513-525.
9. Cohen GB, Ren R, and Baltimore D: Modular binding domains in signal transduction proteins. Cell 1995;80:237-248.
10. Yu H, Chen JK, Feng S, Dalgarno DC, Brauer AW, and Schreiber SL: Structural basis for the binding of proline-rich peptides to SH3 domains. Cell 1994;76:933-945.
11. Lan Z, Kurata WE, Martyn KD, Jin C, and Lau AF: Novel rab GAP-like protein, CIP85, interacts with connexin43 and induces its degradation. Biochemistry 2005;44:2385-2396.
12. Callebaut I, de Gunzburg J, Goud B, and Mornon JP: RUN domains: a new family of domains involved in Ras-like GTPase signaling. Trends Biochem Sci 2001;26:79-83.
13. Itoh T, Satoh M, Kanno E, and Fukuda M: Screening for target Rabs of TBC (Tre-2=Bub2=Cdc16) domain-containing proteins based on their Rab-binding activity. Genes Cells 2006;11:1023-1037.
14. Bernards A: GAPs galore! A survey of putative Ras superfamily GTPase activating proteins in man and Drosophila. Biochim Biophys Acta 2003;1603:47-82.
15. Neuwald AF: A shared domain between a spindle assembly checkpoint protein and Ypt=Rab-specific GTPase-activators. Trends Biochem Sci 1997;22:243-244.
16. Pan X, Eathiraj S, Munson M, and Lambright DG: TBCdomain GAPs for Rab GTPases accelerate GTP hydrolysis by a dual-finger mechanism. Nature 2006;442:303-306.
17. Haas AK, Fuchs E, Kopajtich R, and Barr FA: A GTPaseactivating protein controls Rab5 function in endocytic traf- ficking. Nat Cell Biol 2005;7:887-893.
18. Fuchs E, Haas AK, Spooner RA, Yoshimura S, Lord JM, and Barr FA: Specific Rab GTPase-activating proteins define the Shiga toxin and epidermal growth factor uptake pathways. J Cell Biol 2007;177:1133-1143.
19. Laing JG, Tadros PN, Westphale EM, and Beyer EC: Degradation of connexin43 gap junctions involves both the proteasome and the lysosome. Exp Cell Res 1997;236:482-492.
20. Qin H, Shao Q, Igdoura SA, Alaoui-Jamali MA, and Laird DW: Lysosomal and proteasomal degradation play distinct roles in the life cycle of Cx43 in gap junctional intercellular communication-deficient and -competent breast tumor cells. J Biol Chem 2003;278:30005-30014.
21. Laird DW: Life cycle of connexins in health and disease. Biochem J 2006;394:527-543.
22. Leithe E, Brech A, and Rivedal E: Endocytic processing of connexin43 gap junctions: a morphological study. Biochem J 2006;393:59-67.
23. Gooding J: Monoclonal Antibodies: Principles and Practice, 2e. Academic Press, London, 1986.
24. Loo LW, Berestecky JM, Kanemitsu MY, and Lau AF: pp60src-mediated phosphorylation of connexin 43, a gap junction protein. J Biol Chem 1995;270:12751-12761.
25. Stenmark H, and Olkkonen VM: The Rab GTPase family [review]. Genome Biol 2001;2:3007.